Published in Am J Respir Crit Care Med on January 18, 2007
Adiposity and Airway Inflammation in HIV-Associated Airway Disease (SHOP) | NCT02975258
The incidence of co-morbidities related to obesity and overweight: a systematic review and meta-analysis. BMC Public Health (2009) 9.79
Identification of asthma phenotypes using cluster analysis in the Severe Asthma Research Program. Am J Respir Crit Care Med (2009) 7.17
The morbidity and mortality associated with overweight and obesity in adulthood: a systematic review. Dtsch Arztebl Int (2009) 2.61
Effects of obesity and bariatric surgery on airway hyperresponsiveness, asthma control, and inflammation. J Allergy Clin Immunol (2011) 2.53
Vitamin D levels, lung function, and steroid response in adult asthma. Am J Respir Crit Care Med (2010) 2.40
Retracted Alveolar macrophages from overweight/obese subjects with asthma demonstrate a proinflammatory phenotype. Am J Respir Crit Care Med (2012) 2.39
Does higher body mass index contribute to worse asthma control in an urban population? J Allergy Clin Immunol (2009) 1.79
Obesity and respiratory diseases. Int J Gen Med (2010) 1.68
Body mass and glucocorticoid response in asthma. Am J Respir Crit Care Med (2008) 1.68
Adiponectin deficiency increases allergic airway inflammation and pulmonary vascular remodeling. Am J Respir Cell Mol Biol (2009) 1.65
Asthma control, adiposity, and adipokines among inner-city adolescents. J Allergy Clin Immunol (2010) 1.63
Behavioral weight loss and physical activity intervention in obese adults with asthma. A randomized trial. Ann Am Thorac Soc (2015) 1.58
The nonallergic asthma of obesity. A matter of distal lung compliance. Am J Respir Crit Care Med (2014) 1.57
Cluster analysis of obesity and asthma phenotypes. PLoS One (2012) 1.56
Is chronic asthma associated with shorter leukocyte telomere length at midlife? Am J Respir Crit Care Med (2014) 1.55
Body mass index and asthma incidence in the Black Women's Health Study. J Allergy Clin Immunol (2008) 1.50
Body mass index and phenotype in subjects with mild-to-moderate persistent asthma. J Allergy Clin Immunol (2009) 1.43
Management of asthma in adults. CMAJ (2009) 1.43
Differential association of plasma monocyte chemoattractant protein-1 with systemic inflammatory and airway remodeling biomarkers in type-2 diabetic patients with and without asthma. J Diabetes Metab Disord (2016) 1.41
Obesity, airway hyperresponsiveness, and inflammation. J Appl Physiol (1985) (2009) 1.34
Obesity, adipokines, and lung disease. J Appl Physiol (1985) (2009) 1.30
Health behaviors and quality of life of cancer survivors in Massachusetts, 2006: data use for comprehensive cancer control. Prev Chronic Dis (2009) 1.29
Obesity and asthma: an inflammatory disease of adipose tissue not the airway. Am J Respir Crit Care Med (2012) 1.28
Vitamin D, the immune system and asthma. Expert Rev Clin Immunol (2009) 1.23
Does obesity produce a distinct asthma phenotype? J Appl Physiol (1985) (2009) 1.21
Risk-taking behaviors of adolescents with extreme obesity: normative or not? Pediatrics (2011) 1.21
Asthma in Hispanics. An 8-year update. Am J Respir Crit Care Med (2014) 1.17
Asthma diagnosis and airway bronchodilator response in HIV-infected patients. J Allergy Clin Immunol (2011) 1.13
Effects of liver X receptor agonist treatment on pulmonary inflammation and host defense. J Immunol (2008) 1.11
Gene-gene and gene-environmental interactions of childhood asthma: a multifactor dimension reduction approach. PLoS One (2012) 1.10
Obesity and asthma. Immunol Allergy Clin North Am (2008) 1.10
Challenges in the Management of Asthma in the Elderly. Allergy Asthma Immunol Res (2015) 1.08
Guidelines for diagnosis and management of bronchial asthma: Joint ICS/NCCP (I) recommendations. Lung India (2015) 1.07
Is there a link between obesity and asthma? Allergy Asthma Immunol Res (2014) 1.04
Obesity and airway responsiveness: role of TNFR2. Pulm Pharmacol Ther (2012) 1.03
Effects of BMI, fat mass, and lean mass on asthma in childhood: a Mendelian randomization study. PLoS Med (2014) 1.02
Length of stay and associated costs of obesity related hospital admissions in Ireland. BMC Health Serv Res (2008) 1.01
The Breathe Easier through Weight Loss Lifestyle (BE WELL) Intervention: a randomized controlled trial. BMC Pulm Med (2010) 1.00
Being overweight increases susceptibility to indoor pollutants among urban children with asthma. J Allergy Clin Immunol (2013) 1.00
Incidence of adult-onset asthma after hypothetical interventions on body mass index and physical activity: an application of the parametric g-formula. Am J Epidemiol (2013) 1.00
The impact of diet on asthma and allergic diseases. Nat Rev Immunol (2015) 1.00
Obesity and the lung: 3. Obesity, respiration and intensive care. Thorax (2008) 0.98
A common 16p11.2 inversion underlies the joint susceptibility to asthma and obesity. Am J Hum Genet (2014) 0.97
Airway and plasma leptin and adiponectin in lean and obese asthmatics and controls. J Asthma (2011) 0.96
Asthma disparities and within-group differences in a national, probability sample of same-sex partnered adults. Am J Public Health (2013) 0.96
Obesity, waist size and prevalence of current asthma in the California Teachers Study cohort. Thorax (2009) 0.95
Early childhood weight status in relation to asthma development in high-risk children. J Allergy Clin Immunol (2010) 0.95
Effects of obesity and weight loss on airway physiology and inflammation in asthma. Pulm Pharmacol Ther (2012) 0.94
Comparison of anthropometric measures of obesity in childhood allergic asthma: central obesity is most relevant. J Allergy Clin Immunol (2009) 0.93
A prospective study of weight gain associated with chronotype among college freshmen. Chronobiol Int (2013) 0.93
Innate and ozone-induced airway hyperresponsiveness in obese mice: role of TNF-α. Am J Physiol Lung Cell Mol Physiol (2015) 0.92
Is obesity a risk factor for wheezing among adolescents? A prospective study in southern Brazil. J Adolesc Health (2012) 0.91
Severe and uncontrolled adult asthma is associated with vitamin D insufficiency and deficiency. Respir Res (2013) 0.89
Insulin and the lung: connecting asthma and metabolic syndrome. J Allergy (Cairo) (2013) 0.89
Relationship between obesity and asthma symptoms among children in Ahvaz, Iran: a cross sectional study. Ital J Pediatr (2011) 0.88
Effects of obstructive sleep apnea and gastroesophageal reflux disease on asthma control in obesity. J Asthma (2011) 0.88
Induction of IL-17A Precedes Development of Airway Hyperresponsiveness during Diet-Induced Obesity and Correlates with Complement Factor D. Front Immunol (2014) 0.88
Childhood asthma and obesity--what is the true link? Ann Allergy Asthma Immunol (2014) 0.87
Sex differences: implications for the obesity-asthma association. Exerc Sport Sci Rev (2011) 0.87
Mast cell stabilization: novel medication for obesity and diabetes. Diabetes Metab Res Rev (2011) 0.87
Childhood body mass index and subsequent physician-diagnosed asthma: a systematic review and meta-analysis of prospective cohort studies. BMC Pediatr (2013) 0.87
Optimal management of severe/refractory asthma. Clin Med Insights Circ Respir Pulm Med (2011) 0.86
An unidentified monster in the bed--assessing nocturnal asthma in children. Mcgill J Med (2009) 0.86
Immunometabolism in obese asthmatics: are we there yet? Nutrients (2013) 0.86
Depressed, anxious and breathless missing out: Weight screening in general practice in a regional catchment of New South Wales. Aust J Rural Health (2015) 0.85
Body mass and fat mass in refractory asthma: an observational 1 year follow-up study. J Allergy (Cairo) (2010) 0.85
Monosodium glutamate intake, dietary patterns and asthma in Chinese adults. PLoS One (2012) 0.85
Phenotypes, Risk Factors, and Mechanisms of Adult-Onset Asthma. Mediators Inflamm (2015) 0.85
Impact of maternal obesity on inhaled corticosteroid use in childhood: a registry based analysis of first born children and a sibling pair analysis. PLoS One (2013) 0.84
Role of obesity in asthma control, the obesity-asthma phenotype. J Allergy (Cairo) (2013) 0.84
Role of TNFR1 in the innate airway hyperresponsiveness of obese mice. J Appl Physiol (1985) (2012) 0.84
Obesity in asthma: approaches to treatment. Curr Allergy Asthma Rep (2013) 0.84
Body mass index and comorbidities in adult severe asthmatics. Biomed Res Int (2014) 0.83
Prevalence of symptoms of severe asthma and allergies in Irish school children: an ISAAC protocol study, 1995-2007. Int J Environ Res Public Health (2011) 0.83
Sex differences in the relationship between asthma and overweight in Dutch children: a survey study. PLoS One (2013) 0.83
The asthma phenotype in the obese: distinct or otherwise? J Allergy (Cairo) (2013) 0.82
Effect of physical training on airway inflammation in bronchial asthma: a systematic review. BMC Pulm Med (2013) 0.82
"Causes of death in asthma, COPD and non-respiratory hospitalized patients: a multicentric study". BMC Pulm Med (2013) 0.82
Relationship of adipokines with immune response and lung function in obese asthmatic and non-asthmatic women. J Asthma (2011) 0.82
Obesity increases eosinophil activity in asthmatic children and adolescents. BMC Pulm Med (2013) 0.81
Obesity, metabolic dysregulation and oxidative stress in asthma. Biochim Biophys Acta (2011) 0.81
Obesity and asthma morbidity in a community-based adult cohort in a large urban area: the Chicago Initiative to Raise Asthma Health Equity (CHIRAH). J Asthma (2010) 0.81
Obesity in children with poorly controlled asthma: Sex differences. Pediatr Pulmonol (2012) 0.81
Candidates for bariatric surgery: morbidly obese patients with pulmonary dysfunction. J Obes (2012) 0.81
Obesity: changing asthma in the 21st century. Am J Respir Crit Care Med (2012) 0.81
Obesity and asthma in children: current and future therapeutic options. Paediatr Drugs (2014) 0.81
Obesity and asthma: location, location, location. Eur Respir J (2013) 0.81
Obesity and asthma: physiological perspective. J Allergy (Cairo) (2013) 0.80
Do mast cells link obesity and asthma? Allergy (2012) 0.80
Pulmonary and cardiac function in asymptomatic obese subjects and changes following a structured weight reduction program: a prospective observational study. PLoS One (2014) 0.80
Asthma and metabolic syndrome: Current knowledge and future perspectives. World J Clin Cases (2015) 0.80
Association of insulin resistance with bronchial hyperreactivity. Asia Pac Allergy (2014) 0.80
An elevated body mass index increases lung volume but reduces airflow in Italian schoolchildren. PLoS One (2015) 0.80
Association of Body Mass Index (BMI) with Lung Function Parameters in Non-asthmatics Identified by Spirometric Protocols. J Clin Diagn Res (2014) 0.79
Obesity induced by neonatal overfeeding worsens airway hyperresponsiveness and inflammation. PLoS One (2012) 0.79
Body composition in severe refractory asthma: comparison with COPD patients and healthy smokers. PLoS One (2010) 0.79
The longitudinal relationship of changes of adiposity to changes in pulmonary function and risk of asthma in a general adult population. BMC Pulm Med (2014) 0.79
The systemic inflammome of severe obesity before and after bariatric surgery. PLoS One (2014) 0.79
Understanding asthma and the metabolic syndrome - a Nigerian report. Int Arch Med (2012) 0.79
Exploring the origins of asthma: Lessons from twin studies. Eur Clin Respir J (2014) 0.78
Meta-analysis in clinical trials. Control Clin Trials (1986) 144.91
Bias in meta-analysis detected by a simple, graphical test. BMJ (1997) 122.24
Meta-analysis of observational studies in epidemiology: a proposal for reporting. Meta-analysis Of Observational Studies in Epidemiology (MOOSE) group. JAMA (2000) 55.37
Operating characteristics of a rank correlation test for publication bias. Biometrics (1994) 47.97
Prevalence of overweight and obesity among US children, adolescents, and adults, 1999-2002. JAMA (2004) 25.36
The disease burden associated with overweight and obesity. JAMA (1999) 19.39
Overweight and obesity in the United States: prevalence and trends, 1960-1994. Int J Obes Relat Metab Disord (1998) 11.96
Adiposity as compared with physical activity in predicting mortality among women. N Engl J Med (2004) 8.63
Prospective study of body mass index, weight change, and risk of adult-onset asthma in women. Arch Intern Med (1999) 6.21
Body-mass index and symptoms of gastroesophageal reflux in women. N Engl J Med (2006) 5.24
Overweight, obesity, and health risk. Arch Intern Med (2000) 5.22
Meta-analysis: obesity and the risk for gastroesophageal reflux disease and its complications. Ann Intern Med (2005) 4.52
Obesity and the risk of newly diagnosed asthma in school-age children. Am J Epidemiol (2003) 3.87
Obesity is a risk for asthma and wheeze but not airway hyperresponsiveness. Thorax (2001) 3.27
Obesity may increase the incidence of asthma in women but not in men: longitudinal observations from the Canadian National Population Health Surveys. Am J Epidemiol (2002) 3.01
The epidemiology of obesity and asthma. J Allergy Clin Immunol (2005) 2.87
Birth weight, body mass index and asthma in young adults. Thorax (1999) 2.66
Obesity and asthma. Am J Respir Crit Care Med (2006) 2.43
Influence of body mass index on the response to asthma controller agents. Eur Respir J (2006) 2.41
Obesity is a risk factor for dyspnea but not for airflow obstruction. Arch Intern Med (2002) 2.36
Effect of weight reduction on respiratory function and airway reactivity in obese women. Chest (2004) 2.35
Compliance of the respiratory system and its components in health and obesity. J Appl Physiol (1960) 2.23
Increased effects of smoking and obesity on asthma among female Canadians: the National Population Health Survey, 1994-1995. Am J Epidemiol (1999) 2.13
Asthma is associated with weight gain in females but not males, independent of physical activity. Am J Respir Crit Care Med (2001) 1.96
The relation of body mass index to asthma, chronic bronchitis, and emphysema. Chest (2002) 1.94
Body mass index in relation to adult asthma among 135,000 Norwegian men and women. Am J Epidemiol (2004) 1.88
Pulmonary function and abdominal adiposity in the general population. Chest (2006) 1.74
Pulmonary physiologic changes of morbid obesity. Am J Med Sci (1999) 1.57
The oxygen cost of breathing. Trans Assoc Am Physicians (1954) 1.55
Effects of weight loss on peak flow variability, airways obstruction, and lung volumes in obese patients with asthma. Chest (2000) 1.48
Body mass index, change in body silhouette, and risk of asthma in the E3N cohort study. Am J Epidemiol (2003) 1.38
Obesity and nocturnal gastro-oesophageal reflux are related to onset of asthma and respiratory symptoms. Eur Respir J (2004) 1.30
Body mass index and the risk of asthma in adults. Respir Med (2004) 1.27
Body mass index and asthma incidence among USA adults. Eur Respir J (2004) 1.22
Sex-race differences in the relationship between obesity and asthma: the behavioral risk factor surveillance system, 2000. Ann Epidemiol (2003) 1.21
Factors associated to lifestyle and risk of adult onset asthma. Respir Med (2003) 1.21
Optimized predictions of absolute and relative amounts of body fat from weight, height, other anthropometric predictors, and age 1. Am J Clin Nutr (2006) 1.18
A longitudinal study of adult-onset asthma incidence among HMO members. Environ Health (2003) 1.07
Summary health statistics for the U.S. population: National Health Interview Survey, 2002. Vital Health Stat 10 (2004) 1.05
Obesity and pulmonary function testing. J Allergy Clin Immunol (2005) 0.93
Tiotropium bromide step-up therapy for adults with uncontrolled asthma. N Engl J Med (2010) 6.19
Airway microbiota and bronchial hyperresponsiveness in patients with suboptimally controlled asthma. J Allergy Clin Immunol (2010) 4.38
Predictors of rehospitalization and death after a severe exacerbation of COPD. Chest (2007) 2.67
Obesity and asthma. Am J Respir Crit Care Med (2006) 2.43
A large subgroup of mild-to-moderate asthma is persistently noneosinophilic. Am J Respir Crit Care Med (2012) 1.75
CXCR2 Antagonist MK-7123. A Phase 2 Proof-of-Concept Trial for Chronic Obstructive Pulmonary Disease. Am J Respir Crit Care Med (2015) 1.70
Impact of race on asthma treatment failures in the asthma clinical research network. Am J Respir Crit Care Med (2011) 1.63
Lipoxin generation is related to soluble epoxide hydrolase activity in severe asthma. Am J Respir Crit Care Med (2014) 1.44
The effects of airway microbiome on corticosteroid responsiveness in asthma. Am J Respir Crit Care Med (2013) 1.36
Airway fibroblasts exhibit a synthetic phenotype in severe asthma. J Allergy Clin Immunol (2005) 1.10
Clinical phenotypes of chronic obstructive pulmonary disease and asthma: recent advances. J Allergy Clin Immunol (2013) 1.01
Obesity impairs apoptotic cell clearance in asthma. J Allergy Clin Immunol (2012) 0.98
Safety and efficacy of an inhaled epidermal growth factor receptor inhibitor (BIBW 2948 BS) in chronic obstructive pulmonary disease. Am J Respir Crit Care Med (2009) 0.96
Wildfire smoke and respiratory symptoms in patients with chronic obstructive pulmonary disease. J Allergy Clin Immunol (2005) 0.96
Body mass index and response to asthma therapy: fluticasone propionate/salmeterol versus montelukast. J Asthma (2010) 0.95
Obesity and asthma disease phenotypes. Curr Opin Allergy Clin Immunol (2012) 0.95
Asthma outcomes: symptoms. J Allergy Clin Immunol (2012) 0.93
Vitamin D in asthma: panacea or true promise? J Allergy Clin Immunol (2010) 0.93
Obesity and pulmonary function testing. J Allergy Clin Immunol (2005) 0.93
Effect of increased body mass index on asthma risk, impairment and response to asthma controller therapy in African Americans. Curr Med Res Opin (2010) 0.86
P2X7-regulated protection from exacerbations and loss of control is independent of asthma maintenance therapy. Am J Respir Crit Care Med (2012) 0.81
Predictors of response to tiotropium versus salmeterol in asthmatic adults. J Allergy Clin Immunol (2013) 0.80
Vitamin D and asthma: another dimension. Am J Respir Crit Care Med (2011) 0.80
Sputum induction in COPD--it's safe, so now what do we do? COPD (2006) 0.79
Increased expression of platelet-derived growth factor receptor-beta in airway fibroblasts of severe asthmatics. Chest (2003) 0.78
Modeling the impact of increased adherence to asthma therapy. PLoS One (2012) 0.76
Inhaled steroids and outcomes in COPD: progressing beyond FEV1. Chest (2007) 0.75
Inhaled corticosteroids in chronic obstructive pulmonary disease. Ann Intern Med (2003) 0.75
Interleukin-4 and interleukin-13 augment the proliferative effect of dexamethasone on distal lung fibroblasts. Chest (2003) 0.75
Clinical year in review I: quality improvement for pulmonary and critical care medicine, lung transplantation, rehabilitation for pulmonary and critically ill patients, and sleep medicine. Proc Am Thorac Soc (2012) 0.75