Published in Nucleic Acids Res on January 23, 2007
Selective stabilization of mammalian microRNAs by 3' adenylation mediated by the cytoplasmic poly(A) polymerase GLD-2. Genes Dev (2009) 3.62
Mechanistic characterization of the sulfur-relay system for eukaryotic 2-thiouridine biogenesis at tRNA wobble positions. Nucleic Acids Res (2009) 1.91
Deficit of tRNA(Lys) modification by Cdkal1 causes the development of type 2 diabetes in mice. J Clin Invest (2011) 1.80
Methods for kinetic and thermodynamic analysis of aminoacyl-tRNA synthetases. Methods (2008) 1.46
A cyclic form of N6-threonylcarbamoyladenosine as a widely distributed tRNA hypermodification. Nat Chem Biol (2012) 1.37
Tuning the affinity of aminoacyl-tRNA to elongation factor Tu for optimal decoding. Proc Natl Acad Sci U S A (2011) 1.16
Expanding role of the jumonji C domain as an RNA hydroxylase. J Biol Chem (2010) 1.10
Optimization of the hybridization-based method for purification of thermostable tRNAs in the presence of tetraalkylammonium salts. Nucleic Acids Res (2009) 1.09
Retrograde nuclear import of tRNA precursors is required for modified base biogenesis in yeast. Proc Natl Acad Sci U S A (2011) 1.01
NSUN3 methylase initiates 5-formylcytidine biogenesis in human mitochondrial tRNA(Met). Nat Chem Biol (2016) 0.99
Crystal structure of a novel JmjC-domain-containing protein, TYW5, involved in tRNA modification. Nucleic Acids Res (2010) 0.97
Decoding system for the AUA codon by tRNAIle with the UAU anticodon in Mycoplasma mobile. Nucleic Acids Res (2013) 0.95
The yfiC gene of E. coli encodes an adenine-N6 methyltransferase that specifically modifies A37 of tRNA1Val(cmo5UAC). RNA (2009) 0.94
Actin-binding protein ABP140 is a methyltransferase for 3-methylcytidine at position 32 of tRNAs in Saccharomyces cerevisiae. RNA (2011) 0.91
Rectifier of aberrant mRNA splicing recovers tRNA modification in familial dysautonomia. Proc Natl Acad Sci U S A (2015) 0.91
A multidimensional platform for the purification of non-coding RNA species. Nucleic Acids Res (2013) 0.88
A single acetylation of 18 S rRNA is essential for biogenesis of the small ribosomal subunit in Saccharomyces cerevisiae. J Biol Chem (2014) 0.87
Discovery of the β-barrel-type RNA methyltransferase responsible for N6-methylation of N6-threonylcarbamoyladenosine in tRNAs. Nucleic Acids Res (2014) 0.86
Destabilization of microRNAs in human cells by 3' deadenylation mediated by PARN and CUGBP1. Nucleic Acids Res (2015) 0.85
Taurine-containing uridine modifications in tRNA anticodons are required to decipher non-universal genetic codes in ascidian mitochondria. J Biol Chem (2011) 0.84
Identification of highly-disrupted tRNA genes in nuclear genome of the red alga, Cyanidioschyzon merolae 10D. Sci Rep (2013) 0.81
Biogenesis and growth phase-dependent alteration of 5-methoxycarbonylmethoxyuridine in tRNA anticodons. Nucleic Acids Res (2015) 0.78
Sequence mapping of transfer RNA chemical modifications by liquid chromatography tandem mass spectrometry. Methods (2016) 0.76
Identification of 2-methylthio cyclic N6-threonylcarbamoyladenosine (ms2ct6A) as a novel RNA modification at position 37 of tRNAs. Nucleic Acids Res (2016) 0.76
Decoding mechanism of non-universal genetic codes in Loligo bleekeri mitochondria. J Biol Chem (2013) 0.76
Nonorthogonal tRNA(cys)(Amber) for protein and nascent chain labeling. RNA (2015) 0.75
ALKBH1 is an RNA dioxygenase responsible for cytoplasmic and mitochondrial tRNA modifications. Nucleic Acids Res (2017) 0.75
MicroRNAs: genomics, biogenesis, mechanism, and function. Cell (2004) 198.59
The functions of animal microRNAs. Nature (2004) 64.85
MicroRNAs: small RNAs with a big role in gene regulation. Nat Rev Genet (2004) 37.83
The transcriptional landscape of the mammalian genome. Science (2005) 37.63
Rfam: annotating non-coding RNAs in complete genomes. Nucleic Acids Res (2005) 25.49
Global identification of human transcribed sequences with genome tiling arrays. Science (2004) 17.85
A distinct small RNA pathway silences selfish genetic elements in the germline. Science (2006) 11.63
Non-coding RNA. Hum Mol Genet (2006) 10.57
A germline-specific class of small RNAs binds mammalian Piwi proteins. Nature (2006) 9.88
Non-coding RNA genes and the modern RNA world. Nat Rev Genet (2001) 9.06
A novel class of small RNAs bind to MILI protein in mouse testes. Nature (2006) 8.80
Novel small RNA-encoding genes in the intergenic regions of Escherichia coli. Curr Biol (2001) 7.56
Modulation of microRNA processing and expression through RNA editing by ADAR deaminases. Nat Struct Mol Biol (2005) 7.49
Methylation as a crucial step in plant microRNA biogenesis. Science (2005) 7.16
Methylation protects miRNAs and siRNAs from a 3'-end uridylation activity in Arabidopsis. Curr Biol (2005) 5.99
The RNA Modification Database: 1999 update. Nucleic Acids Res (1999) 4.97
RNA editing of a miRNA precursor. RNA (2004) 4.43
RNA editing of human microRNAs. Genome Biol (2006) 4.16
HEN1 recognizes 21-24 nt small RNA duplexes and deposits a methyl group onto the 2' OH of the 3' terminal nucleotide. Nucleic Acids Res (2006) 3.14
Bacterial small RNA regulators. Crit Rev Biochem Mol Biol (2005) 2.68
Determining the influence of structure on hybridization using oligonucleotide arrays. Nat Biotechnol (1999) 2.46
Small RNAs just got bigger: Piwi-interacting RNAs (piRNAs) in mammalian testes. Genes Dev (2006) 2.17
Taurine as a constituent of mitochondrial tRNAs: new insights into the functions of taurine and human mitochondrial diseases. EMBO J (2002) 1.82
Promising nucleic acid analogs and mimics: characteristic features and applications of PNA, LNA, and morpholino. Appl Microbiol Biotechnol (2006) 1.61
Codon-specific translational defect caused by a wobble modification deficiency in mutant tRNA from a human mitochondrial disease. Proc Natl Acad Sci U S A (2004) 1.47
Riboregulation by DsrA RNA: trans-actions for global economy. Mol Microbiol (2000) 1.42
Wobble modification differences and subcellular localization of tRNAs in Leishmania tarentolae: implication for tRNA sorting mechanism. EMBO J (2003) 1.37
Batchwise purification of specific tRNAs by a solid-phase DNA probe. Anal Biochem (1994) 1.30
Purification and characterization of two serine isoacceptor tRNAs from bovine mitochondria by using a hybridization assay method. Nucleic Acids Res (1989) 1.29
Effect of the higher-order structure of tRNAs on the stability of hybrids with oligodeoxyribonucleotides: separation of tRNA by an efficient solution hybridization. Nucleic Acids Res (1992) 1.19
Modification at position 9 with 1-methyladenosine is crucial for structure and function of nematode mitochondrial tRNAs lacking the entire T-arm. Nucleic Acids Res (2005) 1.05
Pimet, the Drosophila homolog of HEN1, mediates 2'-O-methylation of Piwi- interacting RNAs at their 3' ends. Genes Dev (2007) 4.68
Selective stabilization of mammalian microRNAs by 3' adenylation mediated by the cytoplasmic poly(A) polymerase GLD-2. Genes Dev (2009) 3.62
The TDRD9-MIWI2 complex is essential for piRNA-mediated retrotransposon silencing in the mouse male germline. Dev Cell (2009) 2.96
Hsc70/Hsp90 chaperone machinery mediates ATP-dependent RISC loading of small RNA duplexes. Mol Cell (2010) 2.91
Direct involvement of orexinergic systems in the activation of the mesolimbic dopamine pathway and related behaviors induced by morphine. J Neurosci (2006) 2.84
The 3' termini of mouse Piwi-interacting RNAs are 2'-O-methylated. Nat Struct Mol Biol (2007) 2.71
Mechanistic insights into sulfur relay by multiple sulfur mediators involved in thiouridine biosynthesis at tRNA wobble positions. Mol Cell (2006) 2.71
Recurrence pattern of squamous cell carcinoma of the thoracic esophagus after extended radical esophagectomy with three-field lymphadenectomy. J Am Coll Surg (2004) 2.47
Human mitochondrial mRNAs are stabilized with polyadenylation regulated by mitochondria-specific poly(A) polymerase and polynucleotide phosphorylase. J Biol Chem (2005) 2.02
Mitochondria-specific RNA-modifying enzymes responsible for the biosynthesis of the wobble base in mitochondrial tRNAs. Implications for the molecular pathogenesis of human mitochondrial diseases. J Biol Chem (2004) 1.97
Biosynthesis of wybutosine, a hyper-modified nucleoside in eukaryotic phenylalanine tRNA. EMBO J (2006) 1.95
Mechanistic characterization of the sulfur-relay system for eukaryotic 2-thiouridine biogenesis at tRNA wobble positions. Nucleic Acids Res (2009) 1.91
An RNA-modifying enzyme that governs both the codon and amino acid specificities of isoleucine tRNA. Mol Cell (2003) 1.90
Taurine as a constituent of mitochondrial tRNAs: new insights into the functions of taurine and human mitochondrial diseases. EMBO J (2002) 1.82
Deficit of tRNA(Lys) modification by Cdkal1 causes the development of type 2 diabetes in mice. J Clin Invest (2011) 1.80
Mutation in TRMU related to transfer RNA modification modulates the phenotypic expression of the deafness-associated mitochondrial 12S ribosomal RNA mutations. Am J Hum Genet (2006) 1.79
Agmatine-conjugated cytidine in a tRNA anticodon is essential for AUA decoding in archaea. Nat Chem Biol (2010) 1.68
Mechanism of mRNA deadenylation: evidence for a molecular interplay between translation termination factor eRF3 and mRNA deadenylases. Genes Dev (2007) 1.68
Inhaled Rho kinase inhibitors are potent and selective vasodilators in rat pulmonary hypertension. Am J Respir Crit Care Med (2004) 1.60
Fine-tuning of the ribosomal decoding center by conserved methyl-modifications in the Escherichia coli 16S rRNA. Nucleic Acids Res (2009) 1.52
Snapshots of tRNA sulphuration via an adenylated intermediate. Nature (2006) 1.51
Specific correlation between the wobble modification deficiency in mutant tRNAs and the clinical features of a human mitochondrial disease. Proc Natl Acad Sci U S A (2005) 1.50
Specific residues at every third position of siRNA shape its efficient RNAi activity. Nucleic Acids Res (2007) 1.49
Inosine cyanoethylation identifies A-to-I RNA editing sites in the human transcriptome. Nat Chem Biol (2010) 1.49
Yeast Nfs1p is involved in thio-modification of both mitochondrial and cytoplasmic tRNAs. J Biol Chem (2004) 1.49
Codon-specific translational defect caused by a wobble modification deficiency in mutant tRNA from a human mitochondrial disease. Proc Natl Acad Sci U S A (2004) 1.47
molecular mechanism of lysidine synthesis that determines tRNA identity and codon recognition. Mol Cell (2005) 1.41
The A-site finger in 23 S rRNA acts as a functional attenuator for translocation. J Biol Chem (2006) 1.41
Direct evidence of astrocytic modulation in the development of rewarding effects induced by drugs of abuse. Neuropsychopharmacology (2006) 1.39
A cyclic form of N6-threonylcarbamoyladenosine as a widely distributed tRNA hypermodification. Nat Chem Biol (2012) 1.37
Wobble modification differences and subcellular localization of tRNAs in Leishmania tarentolae: implication for tRNA sorting mechanism. EMBO J (2003) 1.37
Conserved loop sequence of helix 69 in Escherichia coli 23 S rRNA is involved in A-site tRNA binding and translational fidelity. J Biol Chem (2006) 1.32
Outcomes of simultaneous resection of synchronous esophageal and extraesophageal carcinomas. J Am Coll Surg (2002) 1.31
Chronic pain induces anxiety with concomitant changes in opioidergic function in the amygdala. Neuropsychopharmacology (2006) 1.30
Modified uridines with C5-methylene substituents at the first position of the tRNA anticodon stabilize U.G wobble pairing during decoding. J Biol Chem (2008) 1.30
LRPPRC/SLIRP suppresses PNPase-mediated mRNA decay and promotes polyadenylation in human mitochondria. Nucleic Acids Res (2012) 1.29
Poly(A)-specific ribonuclease mediates 3'-end trimming of Argonaute2-cleaved precursor microRNAs. Cell Rep (2013) 1.28
Dual-mode recognition of noncanonical tRNAs(Ser) by seryl-tRNA synthetase in mammalian mitochondria. EMBO J (2005) 1.26
Crystal structure of the radical SAM enzyme catalyzing tricyclic modified base formation in tRNA. J Mol Biol (2007) 1.25
Role of delta-opioid receptor function in neurogenesis and neuroprotection. J Neurochem (2006) 1.23
Direct evidence for the involvement of brain-derived neurotrophic factor in the development of a neuropathic pain-like state in mice. J Neurochem (2005) 1.21
Hippocampal epigenetic modification at the brain-derived neurotrophic factor gene induced by an enriched environment. Hippocampus (2011) 1.20
Direct evidence for spinal cord microglia in the development of a neuropathic pain-like state in mice. J Neurochem (2006) 1.20
Chitosan capsules for colon-specific drug delivery: enhanced localization of 5-aminosalicylic acid in the large intestine accelerates healing of TNBS-induced colitis in rats. J Control Release (2002) 1.18
Direct evidence for the involvement of endogenous beta-endorphin in the suppression of the morphine-induced rewarding effect under a neuropathic pain-like state. Neurosci Lett (2008) 1.17
Identification of two tRNA thiolation genes required for cell growth at extremely high temperatures. J Biol Chem (2006) 1.16
Chaplet column chromatography: isolation of a large set of individual RNAs in a single step. Methods Enzymol (2007) 1.15
Structural basis for translational fidelity ensured by transfer RNA lysidine synthetase. Nature (2009) 1.15
Neuropathic and chronic pain stimuli downregulate central mu-opioid and dopaminergic transmission. Trends Pharmacol Sci (2010) 1.13
Involvement of the Escherichia coli folate-binding protein YgfZ in RNA modification and regulation of chromosomal replication initiation. Mol Microbiol (2006) 1.11
Implication of activated astrocytes in the development of drug dependence: differences between methamphetamine and morphine. Ann N Y Acad Sci (2008) 1.10
Usefulness of antidepressants for improving the neuropathic pain-like state and pain-induced anxiety through actions at different brain sites. Neuropsychopharmacology (2007) 1.10
Expanding role of the jumonji C domain as an RNA hydroxylase. J Biol Chem (2010) 1.10
Identification and characterization of tRNA (Gm18) methyltransferase from Thermus thermophilus HB8: domain structure and conserved amino acid sequence motifs. Genes Cells (2002) 1.10
Suppression of the morphine-induced rewarding effect in the rat with neuropathic pain: implication of the reduction in mu-opioid receptor functions in the ventral tegmental area. J Neurochem (2002) 1.10
A biochemical landscape of A-to-I RNA editing in the human brain transcriptome. Genome Res (2014) 1.09
Common thiolation mechanism in the biosynthesis of tRNA thiouridine and sulphur-containing cofactors. EMBO J (2008) 1.09
Thio modification of yeast cytosolic tRNA is an iron-sulfur protein-dependent pathway. Mol Cell Biol (2007) 1.08
Structural basis for sulfur relay to RNA mediated by heterohexameric TusBCD complex. Structure (2006) 1.08
Comprehensive genetic selection revealed essential bases in the peptidyl-transferase center. Proc Natl Acad Sci U S A (2006) 1.07
Enhanced IL-1beta production in response to the activation of hippocampal glial cells impairs neurogenesis in aged mice. Synapse (2010) 1.07
Biogenesis of glutaminyl-mt tRNAGln in human mitochondria. Proc Natl Acad Sci U S A (2009) 1.06
Conserved bases in the TPsi C loop of tRNA are determinants for thermophile-specific 2-thiouridylation at position 54. J Biol Chem (2002) 1.06
The RNA acetyltransferase driven by ATP hydrolysis synthesizes N4-acetylcytidine of tRNA anticodon. EMBO J (2008) 1.06
The ordered transcription of RNA domains is not essential for ribosome biogenesis in Escherichia coli. Mol Cell (2009) 1.06
Human mitochondrial diseases associated with tRNA wobble modification deficiency. RNA Biol (2005) 1.05
Role of extracellular signal-regulated kinase in the ventral tegmental area in the suppression of the morphine-induced rewarding effect in mice with sciatic nerve ligation. J Neurochem (2004) 1.05
Structural basis for lysidine formation by ATP pyrophosphatase accompanied by a lysine-specific loop and a tRNA-recognition domain. Proc Natl Acad Sci U S A (2005) 1.04
Structural basis of tRNA modification with CO2 fixation and methylation by wybutosine synthesizing enzyme TYW4. Nucleic Acids Res (2009) 1.03
Loss of ribosomal RNA modification causes developmental defects in zebrafish. Nucleic Acids Res (2011) 1.02
Polyadenylation in mammalian mitochondria: insights from recent studies. Biochim Biophys Acta (2008) 1.02
Peritoneovenous shunting for intractable chylous ascites complicated with lymphangioleiomyomatosis. Intern Med (2008) 1.01
Epigenetic transcriptional activation of monocyte chemotactic protein 3 contributes to long-lasting neuropathic pain. Brain (2013) 1.01
Retrograde nuclear import of tRNA precursors is required for modified base biogenesis in yeast. Proc Natl Acad Sci U S A (2011) 1.01
Protease-activated receptor-1 and platelet-derived growth factor in spinal cord neurons are implicated in neuropathic pain after nerve injury. J Neurosci (2005) 1.01
Aquifex aeolicus tRNA (N2,N2-guanine)-dimethyltransferase (Trm1) catalyzes transfer of methyl groups not only to guanine 26 but also to guanine 27 in tRNA. J Biol Chem (2009) 1.01
Structures of tRNAs with an expanded anticodon loop in the decoding center of the 30S ribosomal subunit. RNA (2007) 1.00
The 7472insC mitochondrial DNA mutation impairs the synthesis and extent of aminoacylation of tRNASer(UCN) but not its structure or rate of turnover. J Biol Chem (2002) 1.00
Morphine, oxycodone, and fentanyl exhibit different analgesic profiles in mouse pain models. J Pharmacol Sci (2009) 0.99
RNA helicase module in an acetyltransferase that modifies a specific tRNA anticodon. EMBO J (2009) 0.99
Involvement of a spinal brain-derived neurotrophic factor/full-length TrkB pathway in the development of nerve injury-induced thermal hyperalgesia in mice. Brain Res (2002) 0.99
Antibiotic susceptibility of mammalian mitochondrial translation. FEBS Lett (2005) 0.99
A gene involved in modifying transfer RNA is required for fungal pathogenicity and stress tolerance of Colletotrichum lagenarium. Mol Microbiol (2006) 0.99
Structural basis for nonribosomal peptide synthesis by an aminoacyl-tRNA synthetase paralog. Proc Natl Acad Sci U S A (2011) 0.99
Structural basis of AdoMet-dependent aminocarboxypropyl transfer reaction catalyzed by tRNA-wybutosine synthesizing enzyme, TYW2. Proc Natl Acad Sci U S A (2009) 0.99
Possible pharmacotherapy of the opioid kappa receptor agonist for drug dependence. Ann N Y Acad Sci (2004) 0.98
Prognostic factors and causes of death in patients cured of esophageal cancer. Ann Surg Oncol (2014) 0.98
Memory impairment associated with a dysfunction of the hippocampal cholinergic system induced by prenatal and neonatal exposures to bisphenol-A. Neurosci Lett (2007) 0.98
Crystal structure of a novel JmjC-domain-containing protein, TYW5, involved in tRNA modification. Nucleic Acids Res (2010) 0.97
Molecular basis of dihydrouridine formation on tRNA. Proc Natl Acad Sci U S A (2011) 0.97
Ribosomal RNAs are tolerant toward genetic insertions: evolutionary origin of the expansion segments. Nucleic Acids Res (2008) 0.97
Temperature-dependent biosynthesis of 2-thioribothymidine of Thermus thermophilus tRNA. J Biol Chem (2005) 0.96
The substrate specificity of tRNA (m1G37) methyltransferase (TrmD) from Aquifex aeolicus. Genes Cells (2006) 0.96
Direct evidence for the involvement of the mesolimbic kappa-opioid system in the morphine-induced rewarding effect under an inflammatory pain-like state. Neuropsychopharmacology (2005) 0.96
Chronic pain-induced emotional dysfunction is associated with astrogliosis due to cortical delta-opioid receptor dysfunction. J Neurochem (2006) 0.96
Reversible infantile respiratory chain deficiency: a clinical and molecular study. Ann Neurol (2010) 0.95
Comparative pharmacological profiles of morphine and oxycodone under a neuropathic pain-like state in mice: evidence for less sensitivity to morphine. Neuropsychopharmacology (2007) 0.95
Wobble modification deficiency in mutant tRNAs in patients with mitochondrial diseases. FEBS Lett (2005) 0.95
Decoding system for the AUA codon by tRNAIle with the UAU anticodon in Mycoplasma mobile. Nucleic Acids Res (2013) 0.95
Change in microRNAs associated with neuronal adaptive responses in the nucleus accumbens under neuropathic pain. J Neurosci (2011) 0.94