Published in Biophys J on February 02, 2007
A role for neuronal piRNAs in the epigenetic control of memory-related synaptic plasticity. Cell (2012) 2.72
RGS17, an overexpressed gene in human lung and prostate cancer, induces tumor cell proliferation through the cyclic AMP-PKA-CREB pathway. Cancer Res (2009) 1.07
Signaling logic of activity-triggered dendritic protein synthesis: an mTOR gate but not a feedback switch. PLoS Comput Biol (2009) 0.90
Integrating extrinsic and intrinsic cues into a minimal model of lineage commitment for hematopoietic progenitors. PLoS Comput Biol (2009) 0.89
The sensitivity of memory consolidation and reconsolidation to inhibitors of protein synthesis and kinases: computational analysis. Learn Mem (2010) 0.88
Enhancing E. coli tolerance towards oxidative stress via engineering its global regulator cAMP receptor protein (CRP). PLoS One (2012) 0.87
On the functional diversity of dynamical behaviour in genetic and metabolic feedback systems. BMC Syst Biol (2009) 0.85
Simple molecular networks that respond optimally to time-periodic stimulation. BMC Syst Biol (2009) 0.84
Computational analyses of synergism in small molecular network motifs. PLoS Comput Biol (2014) 0.84
Interlinked dual-time feedback loops can enhance robustness to stochasticity and persistence of memory. Phys Rev E Stat Nonlin Soft Matter Phys (2009) 0.84
Learning-Dependent Gene Expression of CREB1 Isoforms in the Molluscan Brain. Front Behav Neurosci (2010) 0.83
Coupling between feedback loops in autoregulatory networks affects bistability range, open-loop gain and switching times. Phys Biol (2012) 0.83
Noise induced oscillations and coherence resonance in a generic model of the nonisothermal chemical oscillator. Sci Rep (2013) 0.78
Coupled positive and negative feedbacks produce diverse gene expression patterns in colonies. MBio (2015) 0.77
Differences in long-term memory stability and AmCREB level between forward and backward conditioned honeybees (Apis mellifera). Front Behav Neurosci (2015) 0.76
The role of mRNA and protein stability in the function of coupled positive and negative feedback systems in eukaryotic cells. Sci Rep (2015) 0.75
Rescue of impaired long-term facilitation at sensorimotor synapses of Aplysia following siRNA knockdown of CREB1. J Neurosci (2015) 0.75
Bifurcation-based approach reveals synergism and optimal combinatorial perturbation. J Biol Phys (2016) 0.75
Molecular level dynamics of genetic oscillator--the effect of protein-protein interaction. Eur Phys J E Soft Matter (2011) 0.75
Stochasticity in gene expression: from theories to phenotypes. Nat Rev Genet (2005) 14.39
The molecular biology of memory storage: a dialogue between genes and synapses. Science (2001) 11.85
Summing up the noise in gene networks. Nature (2004) 9.62
Self-perpetuating states in signal transduction: positive feedback, double-negative feedback and bistability. Curr Opin Cell Biol (2002) 9.17
Sniffers, buzzers, toggles and blinkers: dynamics of regulatory and signaling pathways in the cell. Curr Opin Cell Biol (2003) 8.91
Function and regulation of CREB family transcription factors in the nervous system. Neuron (2002) 7.99
CREB: a stimulus-induced transcription factor activated by a diverse array of extracellular signals. Annu Rev Biochem (1999) 7.94
Multistability in the lactose utilization network of Escherichia coli. Nature (2004) 7.71
Interlinked fast and slow positive feedback loops drive reliable cell decisions. Science (2005) 6.88
Control, exploitation and tolerance of intracellular noise. Nature (2002) 6.81
Deficient long-term memory in mice with a targeted mutation of the cAMP-responsive element-binding protein. Cell (1994) 6.67
Enhancement of cellular memory by reducing stochastic transitions. Nature (2005) 6.01
Building a cell cycle oscillator: hysteresis and bistability in the activation of Cdc2. Nat Cell Biol (2003) 5.86
The many faces of CREB. Trends Neurosci (2005) 5.58
CREB and memory. Annu Rev Neurosci (1998) 4.76
Programmable cells: interfacing natural and engineered gene networks. Proc Natl Acad Sci U S A (2004) 4.72
Oscillations and variability in the p53 system. Mol Syst Biol (2006) 4.59
Mechanisms of noise-resistance in genetic oscillators. Proc Natl Acad Sci U S A (2002) 3.78
Network motifs in integrated cellular networks of transcription-regulation and protein-protein interaction. Proc Natl Acad Sci U S A (2004) 3.60
Autoinhibition with transcriptional delay: a simple mechanism for the zebrafish somitogenesis oscillator. Curr Biol (2003) 3.56
Regulation of phosphoenolpyruvate carboxykinase (GTP) gene expression. Annu Rev Biochem (1997) 3.45
Bimodal regulation of mPeriod promoters by CREB-dependent signaling and CLOCK/BMAL1 activity. Proc Natl Acad Sci U S A (2002) 3.03
Reversible inhibition of CREB/ATF transcription factors in region CA1 of the dorsal hippocampus disrupts hippocampus-dependent spatial memory. Neuron (2002) 2.87
Inducibility and negative autoregulation of CREM: an alternative promoter directs the expression of ICER, an early response repressor. Cell (1993) 2.84
Aplysia CREB2 represses long-term facilitation: relief of repression converts transient facilitation into long-term functional and structural change. Cell (1995) 2.75
A minimal cascade model for the mitotic oscillator involving cyclin and cdc2 kinase. Proc Natl Acad Sci U S A (1991) 2.68
Motifs, modules and games in bacteria. Curr Opin Microbiol (2003) 2.58
Induction of CRE-mediated gene expression by stimuli that generate long-lasting LTP in area CA1 of the hippocampus. Neuron (1996) 2.47
A plausible model for the digital response of p53 to DNA damage. Proc Natl Acad Sci U S A (2005) 2.32
CREB1 encodes a nuclear activator, a repressor, and a cytoplasmic modulator that form a regulatory unit critical for long-term facilitation. Cell (1998) 2.27
Frequency selectivity, multistability, and oscillations emerge from models of genetic regulatory systems. Am J Physiol (1998) 2.19
Apoptosis, axonal growth defects, and degeneration of peripheral neurons in mice lacking CREB. Neuron (2002) 2.17
CREB: a mediator of long-term memory from mollusks to mammals. Cell (1994) 1.96
Ca2+/cAMP response element-binding protein (CREB)-dependent activation of Per1 is required for light-induced signaling in the suprachiasmatic nucleus circadian clock. J Biol Chem (2002) 1.87
Inducible enhancement of memory storage and synaptic plasticity in transgenic mice expressing an inhibitor of ATF4 (CREB-2) and C/EBP proteins. Neuron (2003) 1.80
Memory suppressor genes: inhibitory constraints on the storage of long-term memory. Science (1998) 1.76
Targeting the CREB pathway for memory enhancers. Nat Rev Drug Discov (2003) 1.72
Sensitivity analysis of discrete stochastic systems. Biophys J (2005) 1.70
The stability of a stochastic CaMKII switch: dependence on the number of enzyme molecules and protein turnover. PLoS Biol (2005) 1.70
Nonlinear protein degradation and the function of genetic circuits. Proc Natl Acad Sci U S A (2005) 1.65
The sonic hedgehog signaling system as a bistable genetic switch. Biophys J (2004) 1.61
A reduced model clarifies the role of feedback loops and time delays in the Drosophila circadian oscillator. Biophys J (2002) 1.39
Repeated pulses of serotonin required for long-term facilitation activate mitogen-activated protein kinase in sensory neurons of Aplysia. Proc Natl Acad Sci U S A (1998) 1.37
Stochastic models for circadian rhythms: effect of molecular noise on periodic and chaotic behaviour. C R Biol (2003) 1.34
Deterministic versus stochastic models for circadian rhythms. J Biol Phys (2002) 1.27
Circadian rhythms and molecular noise. Chaos (2006) 1.22
Gene regulatory networks: a coarse-grained, equation-free approach to multiscale computation. J Chem Phys (2006) 1.18
Determination of the exact copy numbers of particular mRNAs in a single cell by quantitative real-time RT-PCR. J Exp Biol (2005) 1.14
cAMP-response elements in Aplysia creb1, creb2, and Ap-uch promoters: implications for feedback loops modulating long term memory. J Biol Chem (2005) 1.14
Dynamics of induction and expression of long-term synaptic facilitation in Aplysia. J Neurosci (1996) 1.13
CREB in the mouse SCN: a molecular interface coding the phase-adjusting stimuli light, glutamate, PACAP, and melatonin for clockwork access. J Neurosci (1998) 1.10
Effects of macromolecular transport and stochastic fluctuations on dynamics of genetic regulatory systems. Am J Physiol (1999) 1.08
Design principles for regulator gene expression in a repressible gene circuit. J Mol Biol (2003) 1.07
Transition from stochastic to deterministic behavior in calcium oscillations. Biophys J (2005) 1.07
The promoter of the gene encoding 3',5'-cyclic adenosine monophosphate (cAMP) response element binding protein contains cAMP response elements: evidence for positive autoregulation of gene transcription. Endocrinology (1993) 1.04
Expression of the gene encoding transcription factor cyclic adenosine 3',5'-monophosphate (cAMP) response element-binding protein (CREB): regulation by follicle-stimulating hormone-induced cAMP signaling in primary rat Sertoli cells. Endocrinology (1995) 0.99
Dynamic properties of regulatory motifs associated with induction of three temporal domains of memory in aplysia. J Comput Neurosci (2005) 0.90
Bifurcation and singularity analysis of a molecular network for the induction of long-term memory. Biophys J (2006) 0.84
Operant reward learning in Aplysia: neuronal correlates and mechanisms. Science (2002) 2.29
Calcium and glycolysis mediate multiple bursting modes in pancreatic islets. Biophys J (2004) 1.68
Teaching basic principles of neuroscience with computer simulations. J Undergrad Neurosci Educ (2006) 1.52
A reduced model clarifies the role of feedback loops and time delays in the Drosophila circadian oscillator. Biophys J (2002) 1.39
Simulation of Drosophila circadian oscillations, mutations, and light responses by a model with VRI, PDP-1, and CLK. Biophys J (2004) 1.38
More than synaptic plasticity: role of nonsynaptic plasticity in learning and memory. Trends Neurosci (2009) 1.33
Feeding behavior of Aplysia: a model system for comparing cellular mechanisms of classical and operant conditioning. Learn Mem (2006) 1.26
cAMP response element-binding protein 1 feedback loop is necessary for consolidation of long-term synaptic facilitation in Aplysia. J Neurosci (2008) 1.24
cAMP-response elements in Aplysia creb1, creb2, and Ap-uch promoters: implications for feedback loops modulating long term memory. J Biol Chem (2005) 1.14
Classical and operant conditioning differentially modify the intrinsic properties of an identified neuron. Nat Neurosci (2005) 1.12
Localized neuronal outgrowth induced by long-term sensitization training in aplysia. J Neurosci (2002) 1.09
Computational design of enhanced learning protocols. Nat Neurosci (2011) 1.07
Serotonin stimulates phosphorylation of Aplysia synapsin and alters its subcellular distribution in sensory neurons. J Neurosci (2002) 1.04
Molecular mechanisms underlying a cellular analog of operant reward learning. Neuron (2008) 1.03
The requirement for enhanced CREB1 expression in consolidation of long-term synaptic facilitation and long-term excitability in sensory neurons of Aplysia. J Neurosci (2011) 1.03
A model of the roles of essential kinases in the induction and expression of late long-term potentiation. Biophys J (2006) 1.00
Changes in neuronal excitability serve as a mechanism of long-term memory for operant conditioning. Nat Neurosci (2008) 0.99
Learning insights transmitted by glutamate. Trends Neurosci (2004) 0.99
The ubiquitin-proteasome system is necessary for long-term synaptic depression in Aplysia. J Neurosci (2008) 0.98
Current- and voltage-clamp recordings and computer simulations of Kenyon cells in the honeybee. J Neurophysiol (2004) 0.98
Multimodal behavior in a four neuron ring circuit: mode switching. IEEE Trans Biomed Eng (2004) 0.96
Protein degradation and memory formation. Brain Res Bull (2010) 0.96
TGF-beta1-induced long-term changes in neuronal excitability in aplysia sensory neurons depend on MAPK. J Neurophysiol (2006) 0.95
Bistable MAP kinase activity: a plausible mechanism contributing to maintenance of late long-term potentiation. Am J Physiol Cell Physiol (2007) 0.93
Transforming growth factor-beta2 modulates synaptic efficacy and plasticity and induces phosphorylation of CREB in hippocampal neurons. Hippocampus (2007) 0.92
Coregulation of glutamate uptake and long-term sensitization in Aplysia. J Neurosci (2004) 0.92
Dynamic properties of regulatory motifs associated with induction of three temporal domains of memory in aplysia. J Comput Neurosci (2005) 0.90
Long-term sensitization training primes Aplysia for further learning. Learn Mem (2006) 0.89
Computational model of touch sensory cells (T Cells) of the leech: role of the afterhyperpolarization (AHP) in activity-dependent conduction failure. J Comput Neurosci (2005) 0.88
Mechanisms underlying fictive feeding in aplysia: coupling between a large neuron with plateau potentials activity and a spiking neuron. J Neurophysiol (2002) 0.88
Serotonin- and training-induced dynamic regulation of CREB2 in Aplysia. Learn Mem (2011) 0.88
The sensitivity of memory consolidation and reconsolidation to inhibitors of protein synthesis and kinases: computational analysis. Learn Mem (2010) 0.88
In vitro analog of classical conditioning of feeding behavior in aplysia. Learn Mem (2003) 0.86
Dissociation of morphological and physiological changes associated with long-term memory in aplysia. J Neurophysiol (2004) 0.86
Quantitation of contacts among sensory, motor, and serotonergic neurons in the pedal ganglion of aplysia. Learn Mem (2003) 0.86
Molecular constraints on synaptic tagging and maintenance of long-term potentiation: a predictive model. PLoS Comput Biol (2012) 0.85
Modeling interactions between electrical activity and second-messenger cascades in Aplysia neuron R15. J Neurophysiol (2003) 0.85
Deficit in long-term synaptic plasticity is rescued by a computationally predicted stimulus protocol. J Neurosci (2013) 0.85
Long-term sensitization training produces spike narrowing in Aplysia sensory neurons. J Neurosci (2007) 0.84
Serotonin-mediated synapsin expression is necessary for long-term facilitation of the Aplysia sensorimotor synapse. J Neurosci (2011) 0.84
Bifurcation and singularity analysis of a molecular network for the induction of long-term memory. Biophys J (2006) 0.84
Interlinked dual-time feedback loops can enhance robustness to stochasticity and persistence of memory. Phys Rev E Stat Nonlin Soft Matter Phys (2009) 0.84
Burst-induced synaptic depression and its modulation contribute to information transfer at Aplysia sensorimotor synapses: empirical and computational analyses. J Neurosci (2003) 0.83
Desensitization of postsynaptic glutamate receptors contributes to high-frequency homosynaptic depression of aplysia sensorimotor connections. Learn Mem (2003) 0.82
The 5-HT- and FMRFa-activated signaling pathways interact at the level of the Erk MAPK cascade: potential inhibitory constraints on memory formation. Neurosci Lett (2005) 0.82
An aplysia dopamine1-like receptor: molecular and functional characterization. J Neurochem (2005) 0.82
Synapsin regulates Basal synaptic strength, synaptic depression, and serotonin-induced facilitation of sensorimotor synapses in Aplysia. J Neurophysiol (2007) 0.81
Spontaneous activity of dopaminergic retinal neurons. Biophys J (2003) 0.81
Computational study of enhanced excitability in Hermissenda: membrane conductances modulated by 5-HT. J Comput Neurosci (2003) 0.80
Reinforcement in an in vitro analog of appetitive classical conditioning of feeding behavior in Aplysia: blockade by a dopamine antagonist. Learn Mem (2005) 0.80
Extending in vitro conditioning in Aplysia to analyze operant and classical processes in the same preparation. Learn Mem (2004) 0.80
Voltage-clamp analysis and computational model of dopaminergic neurons from mouse retina. Vis Neurosci (2005) 0.80
Reduced models of the circadian oscillators in Neurospora crassa and Drosophila melanogaster illustrate mechanistic similarities. OMICS (2003) 0.80
A computational study of the role of spike broadening in synaptic facilitation of Hermissenda. J Comput Neurosci (2003) 0.79
Analysis of 5-HT-induced short-term facilitation at Aplysia sensorimotor synapse during bursts: increased synaptic gain that does not require ERK activation. J Neurophysiol (2005) 0.78
Short-Term Plasticity in a Computational Model of the Tail-Withdrawal Circuit in Aplysia. Neurocomputing (2007) 0.77
Inhibitor of glutamate transport alters synaptic transmission at sensorimotor synapses in Aplysia. J Neurophysiol (2002) 0.77
Classical conditioning analog enhanced acetylcholine responses but reduced excitability of an identified neuron. J Neurosci (2011) 0.76
Simulator for neural networks and action potentials. Methods Mol Biol (2007) 0.76
Correlation between activity in neuron B52 and two features of fictive feeding in Aplysia. Neurosci Lett (2002) 0.76
Post-translational regulation of an Aplysia glutamate transporter during long-term facilitation. J Neurochem (2008) 0.75
Special issue on the effect of fear and stress on memory. Learn Mem (2017) 0.75
Special issue on molecular and cellular cognition. Learn Mem (2017) 0.75
Special issue on molecular and cellular cognition. Learn Mem (2015) 0.75