Published in BMC Syst Biol on March 03, 2009
Decoding GnRH neurohormone pulse frequency by convergent signalling modules. J R Soc Interface (2011) 0.83
Trade-offs and noise tolerance in signal detection by genetic circuits. PLoS One (2010) 0.82
Processing Oscillatory Signals by Incoherent Feedforward Loops. PLoS Comput Biol (2016) 0.76
Differential gene expression regulated by oscillatory transcription factors. PLoS One (2012) 0.76
Genetic Deletion of the Transcriptional Repressor NFIL3 Enhances Axon Growth In Vitro but Not Axonal Repair In Vivo. PLoS One (2015) 0.75
A synthetic oscillatory network of transcriptional regulators. Nature (2000) 24.58
Construction of a genetic toggle switch in Escherichia coli. Nature (2000) 24.02
Gene regulation at the single-cell level. Science (2005) 11.52
An amplified sensitivity arising from covalent modification in biological systems. Proc Natl Acad Sci U S A (1981) 10.04
Calcium oscillations increase the efficiency and specificity of gene expression. Nature (1998) 9.19
Sensitivity of CaM kinase II to the frequency of Ca2+ oscillations. Science (1998) 7.29
Development of genetic circuitry exhibiting toggle switch or oscillatory behavior in Escherichia coli. Cell (2003) 6.03
The logical analysis of continuous, non-linear biochemical control networks. J Theor Biol (1973) 5.02
Negative feedback and ultrasensitivity can bring about oscillations in the mitogen-activated protein kinase cascades. Eur J Biochem (2000) 4.99
The frequency dependence of osmo-adaptation in Saccharomyces cerevisiae. Science (2008) 4.94
Oscillations and variability in the p53 system. Mol Syst Biol (2006) 4.59
Circadian clocks limited by noise. Nature (2000) 4.39
Mathematical models of protein kinase signal transduction. Mol Cell (2002) 4.08
The incoherent feed-forward loop accelerates the response-time of the gal system of Escherichia coli. J Mol Biol (2005) 3.13
Robustness of circadian rhythms with respect to molecular noise. Proc Natl Acad Sci U S A (2002) 3.13
CREB as a memory modulator: induced expression of a dCREB2 activator isoform enhances long-term memory in Drosophila. Cell (1995) 3.00
Minimal model for signal-induced Ca2+ oscillations and for their frequency encoding through protein phosphorylation. Proc Natl Acad Sci U S A (1990) 2.97
Deep brain stimulation. Annu Rev Neurosci (2006) 2.65
Motifs, modules and games in bacteria. Curr Opin Microbiol (2003) 2.58
Signal processing by the HOG MAP kinase pathway. Proc Natl Acad Sci U S A (2008) 2.56
Steady states and oscillations in the p53/Mdm2 network. Cell Cycle (2005) 2.45
The dynamics of cell cycle regulation. Bioessays (2002) 2.21
Frequency selectivity, multistability, and oscillations emerge from models of genetic regulatory systems. Am J Physiol (1998) 2.19
The neurospora circadian system. J Biol Rhythms (2004) 2.06
Long-term habituation of a defensive withdrawal reflex in aplysia. Science (1972) 1.89
A mechanism for exact sensory adaptation based on receptor modification. J Theor Biol (1986) 1.54
Operating regimes of signaling cycles: statics, dynamics, and noise filtering. PLoS Comput Biol (2007) 1.51
The use of oscillatory signals in the study of genetic networks. Proc Natl Acad Sci U S A (2005) 1.45
An evolutionary and functional assessment of regulatory network motifs. Genome Biol (2005) 1.45
A hidden feedback in signaling cascades is revealed. PLoS Comput Biol (2008) 1.41
Sensitivity of CaM kinase II to the frequency of Ca2+ oscillations: a simple model. Cell Calcium (2003) 1.25
Dynamical principles of two-component genetic oscillators. PLoS Comput Biol (2006) 1.24
Frequency specificity in intercellular communication. Influence of patterns of periodic signaling on target cell responsiveness. Biophys J (1989) 1.24
Cell surface receptors for signal transduction and ligand transport: a design principles study. PLoS Comput Biol (2007) 1.21
Frequency domain analysis of noise in simple gene circuits. Chaos (2006) 1.15
Dynamics of a minimal model of interlocked positive and negative feedback loops of transcriptional regulation by cAMP-response element binding proteins. Biophys J (2007) 1.10
The molecular biology of memory storage: a dialog between genes and synapses. Biosci Rep (2005) 1.09
Receptor downregulation and desensitization enhance the information processing ability of signalling receptors. BMC Syst Biol (2007) 0.92
Deep brain stimulation in a rat model modulates TH, CaMKIIa and Homer1 gene expression. Eur J Neurosci (2007) 0.90
Protein phosphorylation driven by intracellular calcium oscillations: a kinetic analysis. Biophys Chem (1992) 0.90
Signal duration and the time scale dependence of signal integration in biochemical pathways. BMC Syst Biol (2008) 0.81
Toward a quantitative modeling of the synthesis of the pectate lyases, essential virulence factors in Dickeya dadantii. J Biol Chem (2010) 0.80
Modelling the onset of virulence in pathogenic bacteria. Methods Mol Biol (2012) 0.76