Published in Clin Infect Dis on March 01, 2007
Rapid Empiric Treatment With Oseltamivir Study (RETOS) (RETOS) | NCT01248715
PCR to Guide Antibiotic Therapy for Pneumonia | NCT02660554
Procalcitonin Use in Pneumonia Patients in the Critical Care Setting | NCT01788488
Duration of Antibiotic Therapy in Community - Acquired Pneumonia (DURATION) | NCT01492387
Failure and Cardiovascular Events in Community-acquired Pneumonia (FAILCAP) | NCT01143155
Bolus Versus Continuous Infusion of Meropenem (MERCY) | NCT03452839
Multi-Drug Resistant Organism Network (MDRO Network) | NCT03646227
Shortened Antibiotic Treatment of 5 Days in Community-Acquired Pneumonia (CAP5) | NCT04089787
Hospital-acquired infections due to gram-negative bacteria. N Engl J Med (2010) 6.61
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Antibiotic prescription rates for acute respiratory tract infections in US ambulatory settings. JAMA (2009) 4.61
Intensive care adult patients with severe respiratory failure caused by Influenza A (H1N1)v in Spain. Crit Care (2009) 4.45
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New perspectives on community-acquired pneumonia in 388 406 patients. Results from a nationwide mandatory performance measurement programme in healthcare quality. Thorax (2009) 3.21
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Effectiveness of manual therapies: the UK evidence report. Chiropr Osteopat (2010) 2.93
Bundled care for septic shock: an analysis of clinical trials. Crit Care Med (2010) 2.57
Validation of the Infectious Disease Society of America/American Thoracic Society 2007 guidelines for severe community-acquired pneumonia. Crit Care Med (2009) 2.32
Mechanisms of action and clinical application of macrolides as immunomodulatory medications. Clin Microbiol Rev (2010) 2.32
Observational study of inhaled corticosteroids on outcomes for COPD patients with pneumonia. Am J Respir Crit Care Med (2011) 2.30
Fluoroquinolone resistance in Mycobacterium tuberculosis: the effect of duration and timing of fluoroquinolone exposure. Am J Respir Crit Care Med (2009) 2.18
Therapeutic strategies for severe acute lung injury. Crit Care Med (2010) 2.12
Septic shock and adequacy of early empiric antibiotics in the emergency department. J Emerg Med (2014) 2.09
A guide to utilization of the microbiology laboratory for diagnosis of infectious diseases: 2013 recommendations by the Infectious Diseases Society of America (IDSA) and the American Society for Microbiology (ASM)(a). Clin Infect Dis (2013) 2.08
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Population-based study of statins, angiotensin II receptor blockers, and angiotensin-converting enzyme inhibitors on pneumonia-related outcomes. Clin Infect Dis (2012) 1.75
Critically ill children during the 2009-2010 influenza pandemic in the United States. Pediatrics (2011) 1.74
Differences in immune response may explain lower survival among older men with pneumonia. Crit Care Med (2009) 1.71
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Tropheryma whipplei in patients with pneumonia. Emerg Infect Dis (2010) 1.59
Increase in pneumococcus macrolide resistance, United States. Emerg Infect Dis (2009) 1.54
Hospitals with the highest intensive care utilization provide lower quality pneumonia care to the elderly. Crit Care Med (2015) 1.53
Detection of 11 common viral and bacterial pathogens causing community-acquired pneumonia or sepsis in asymptomatic patients by using a multiplex reverse transcription-PCR assay with manual (enzyme hybridization) or automated (electronic microarray) detection. J Clin Microbiol (2008) 1.51
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Lung ultrasound for the diagnosis of pneumonia in adults: a systematic review and meta-analysis. Respir Res (2014) 1.44
Trends in Antibiotic Use and Nosocomial Pathogens in Hospitalized Veterans With Pneumonia at 128 Medical Centers, 2006-2010. Clin Infect Dis (2015) 1.44
General principles of antimicrobial therapy. Mayo Clin Proc (2011) 1.42
Current and emerging Legionella diagnostics for laboratory and outbreak investigations. Clin Microbiol Rev (2015) 1.41
Clinical pharmacodynamics of cefepime in patients infected with Pseudomonas aeruginosa. Antimicrob Agents Chemother (2009) 1.40
Generation and Improvement of Effector Function of a Novel Broadly Reactive and Protective Monoclonal Antibody against Pneumococcal Surface Protein A of Streptococcus pneumoniae. PLoS One (2016) 1.40
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Multiplex identification of gram-positive bacteria and resistance determinants directly from positive blood culture broths: evaluation of an automated microarray-based nucleic acid test. PLoS Med (2013) 1.40
Pneumococcal lower respiratory tract infections in adults: an observational case-control study in primary care in Belgium. BMC Fam Pract (2015) 1.39
Haemophilus influenzae infections in the H. influenzae type b conjugate vaccine era. J Clin Microbiol (2011) 1.38
Risk factors for mortality in patients admitted to intensive care units with pneumonia. Respir Res (2016) 1.37
Lower respiratory tract virus findings in mechanically ventilated patients with severe community-acquired pneumonia. Clin Infect Dis (2014) 1.36
Marked reduction in 30-day mortality among elderly patients with community-acquired pneumonia. Am J Med (2011) 1.36
Brazilian recommendations of mechanical ventilation 2013. Part I. Rev Bras Ter Intensiva (2014) 1.35
Current concepts in antimicrobial therapy against select gram-positive organisms: methicillin-resistant Staphylococcus aureus, penicillin-resistant pneumococci, and vancomycin-resistant enterococci. Mayo Clin Proc (2011) 1.33
Variability in processes of care and outcomes among children hospitalized with community-acquired pneumonia. Pediatr Infect Dis J (2012) 1.33
Clinical use of anti-TNF therapy and increased risk of infections. Drug Healthc Patient Saf (2013) 1.31
Effect of corticosteroids on the clinical course of community-acquired pneumonia: a randomized controlled trial. Crit Care (2011) 1.30
Comprehensive quality of discharge summaries at an academic medical center. J Hosp Med (2013) 1.30
Trends in antibacterial resistance among Streptococcus pneumoniae isolated in the USA: update from PROTEKT US Years 1-4. Ann Clin Microbiol Antimicrob (2008) 1.29
Pharmacodynamic characterization of ceftobiprole in experimental pneumonia caused by phenotypically diverse Staphylococcus aureus strains. Antimicrob Agents Chemother (2008) 1.29
Risk stratification of early admission to the intensive care unit of patients with no major criteria of severe community-acquired pneumonia: development of an international prediction rule. Crit Care (2009) 1.27
Critical role of IL-1 receptor-associated kinase-M in regulating chemokine-dependent deleterious inflammation in murine influenza pneumonia. J Immunol (2009) 1.27
Systematic review and meta-analysis of a urine-based pneumococcal antigen test for diagnosis of community-acquired pneumonia caused by Streptococcus pneumoniae. J Clin Microbiol (2013) 1.25
Investigations of Mycoplasma pneumoniae infections in the United States: trends in molecular typing and macrolide resistance from 2006 to 2013. J Clin Microbiol (2014) 1.24
The neutrophil-lymphocyte count ratio in patients with community-acquired pneumonia. PLoS One (2012) 1.24
Pneumonia identification using statistical feature selection. J Am Med Inform Assoc (2012) 1.23
The aetiology and antibiotic management of community-acquired pneumonia in adults in Europe: a literature review. Eur J Clin Microbiol Infect Dis (2014) 1.22
Cigarette smoke exposure impairs pulmonary bacterial clearance and alveolar macrophage complement-mediated phagocytosis of Streptococcus pneumoniae. Infect Immun (2009) 1.22
Outcomes of early switching from intravenous to oral antibiotics on medical wards. J Antimicrob Chemother (2009) 1.22
Clinical and temporal patterns of severe pneumonia causing critical illness during Hajj. BMC Infect Dis (2012) 1.22
The influence of macrophage migration inhibitory factor gene polymorphisms on outcome from community-acquired pneumonia. FASEB J (2009) 1.22
Role of C-reactive protein and procalcitonin in differentiation of tuberculosis from bacterial community acquired pneumonia. Korean J Intern Med (2009) 1.21
High discordance of chest x-ray and computed tomography for detection of pulmonary opacities in ED patients: implications for diagnosing pneumonia. Am J Emerg Med (2012) 1.21
Changes in fluoroquinolone-resistant Streptococcus pneumoniae after 7-valent conjugate vaccination, Spain. Emerg Infect Dis (2009) 1.19
Efficacy of osteopathic manipulation as an adjunctive treatment for hospitalized patients with pneumonia: a randomized controlled trial. Osteopath Med Prim Care (2010) 1.19
Human antibody responses to avian influenza A(H7N9) virus, 2013. Emerg Infect Dis (2014) 1.19
Interpreting assays for the detection of Streptococcus pneumoniae. Clin Infect Dis (2011) 1.19
Variability in pediatric infectious disease consultants' recommendations for management of community-acquired pneumonia. PLoS One (2011) 1.18
Bench-to-bedside review: bacterial pneumonia with influenza - pathogenesis and clinical implications. Crit Care (2010) 1.18
Respiratory Viral Detection in Children and Adults: Comparing Asymptomatic Controls and Patients With Community-Acquired Pneumonia. J Infect Dis (2015) 1.17
Risk of community-acquired pneumonia with outpatient proton-pump inhibitor therapy: a systematic review and meta-analysis. PLoS One (2015) 1.17
Prohormones for prediction of adverse medical outcome in community-acquired pneumonia and lower respiratory tract infections. Crit Care (2010) 1.17
Enhancement of CURB65 score with proadrenomedullin (CURB65-A) for outcome prediction in lower respiratory tract infections: derivation of a clinical algorithm. BMC Infect Dis (2011) 1.15
Should lower respiratory tract secretions from intensive care patients be systematically screened for influenza virus during the influenza season? Crit Care (2012) 1.14
Changing needs of community-acquired pneumonia. J Antimicrob Chemother (2011) 1.14
Serious invasive Saffold virus infections in children, 2009. Emerg Infect Dis (2012) 1.13
Position paper: recommended design features of future clinical trials of antibacterial agents for community-acquired pneumonia. Clin Infect Dis (2008) 1.11
Control of fluoroquinolone resistance through successful regulation, Australia. Emerg Infect Dis (2012) 1.11
Blood cultures in the emergency department evaluation of childhood pneumonia. Pediatr Infect Dis J (2011) 1.11
Hospital admission decision for patients with community-acquired pneumonia: variability among physicians in an emergency department. Ann Emerg Med (2011) 1.10
Recent exposure to antimicrobials and carbapenem-resistant Enterobacteriaceae: the role of antimicrobial stewardship. Infect Control Hosp Epidemiol (2012) 1.10
Demographics, guidelines, and clinical experience in severe community-acquired pneumonia. Crit Care (2008) 1.10
Viral and Mycoplasma pneumoniae community-acquired pneumonia and novel clinical outcome evaluation in ambulatory adult patients in China. Eur J Clin Microbiol Infect Dis (2010) 1.10
E-prostanoid 3 receptor deletion improves pulmonary host defense and protects mice from death in severe Streptococcus pneumoniae infection. J Immunol (2009) 1.10
Repertoire of intensive care unit pneumonia microbiota. PLoS One (2012) 1.10
Duration of antibiotic therapy for bacteremia: a systematic review and meta-analysis. Crit Care (2011) 1.10
Epidemiology and outcome of severe pneumococcal pneumonia admitted to intensive care unit: a multicenter study. Crit Care (2012) 1.09
Corticosteroids in the treatment of community-acquired pneumonia in adults: a meta-analysis. PLoS One (2012) 1.09
Community-acquired polymicrobial pneumonia in the intensive care unit: aetiology and prognosis. Crit Care (2011) 1.09
Global strategy for the diagnosis, management, and prevention of chronic obstructive pulmonary disease: GOLD executive summary. Am J Respir Crit Care Med (2007) 47.86
An official ATS/IDSA statement: diagnosis, treatment, and prevention of nontuberculous mycobacterial diseases. Am J Respir Crit Care Med (2007) 33.18
A novel coronavirus associated with severe acute respiratory syndrome. N Engl J Med (2003) 29.55
Guidelines for the management of adults with hospital-acquired, ventilator-associated, and healthcare-associated pneumonia. Am J Respir Crit Care Med (2005) 23.85
Global strategy for the diagnosis, management, and prevention of chronic obstructive pulmonary disease: GOLD executive summary. Am J Respir Crit Care Med (2012) 22.96
Clinical practice guidelines for the management of candidiasis: 2009 update by the Infectious Diseases Society of America. Clin Infect Dis (2009) 18.19
Clinical practice guidelines for Clostridium difficile infection in adults: 2010 update by the society for healthcare epidemiology of America (SHEA) and the infectious diseases society of America (IDSA). Infect Control Hosp Epidemiol (2010) 17.99
Treatment of aspergillosis: clinical practice guidelines of the Infectious Diseases Society of America. Clin Infect Dis (2008) 16.51
Susceptibility to exacerbation in chronic obstructive pulmonary disease. N Engl J Med (2010) 15.07
Infectious Diseases Society of America and the Society for Healthcare Epidemiology of America guidelines for developing an institutional program to enhance antimicrobial stewardship. Clin Infect Dis (2006) 14.63
Probable person-to-person transmission of avian influenza A (H5N1). N Engl J Med (2005) 14.59
International clinical practice guidelines for the treatment of acute uncomplicated cystitis and pyelonephritis in women: A 2010 update by the Infectious Diseases Society of America and the European Society for Microbiology and Infectious Diseases. Clin Infect Dis (2011) 12.29
International study of the prevalence and outcomes of infection in intensive care units. JAMA (2009) 11.57
Clinical practice guidelines by the infectious diseases society of america for the treatment of methicillin-resistant Staphylococcus aureus infections in adults and children. Clin Infect Dis (2011) 11.49
ATS/ERS recommendations for standardized procedures for the online and offline measurement of exhaled lower respiratory nitric oxide and nasal nitric oxide, 2005. Am J Respir Crit Care Med (2005) 11.34
Anthrax as a biological weapon, 2002: updated recommendations for management. JAMA (2002) 10.40
The epidemic of antibiotic-resistant infections: a call to action for the medical community from the Infectious Diseases Society of America. Clin Infect Dis (2008) 9.57
Clinical practice guideline for the use of antimicrobial agents in neutropenic patients with cancer: 2010 update by the infectious diseases society of america. Clin Infect Dis (2011) 9.37
Practice guidelines for the diagnosis and management of skin and soft-tissue infections. Clin Infect Dis (2005) 9.23
Guidelines for the management of adults with community-acquired pneumonia. Diagnosis, assessment of severity, antimicrobial therapy, and prevention. Am J Respir Crit Care Med (2001) 9.08
Idiopathic pulmonary fibrosis: prevailing and evolving hypotheses about its pathogenesis and implications for therapy. Ann Intern Med (2001) 8.95
ATS/ACCP Statement on cardiopulmonary exercise testing. Am J Respir Crit Care Med (2003) 8.83
Bad bugs need drugs: an update on the development pipeline from the Antimicrobial Availability Task Force of the Infectious Diseases Society of America. Clin Infect Dis (2005) 8.77
Diagnosis and management of prosthetic joint infection: clinical practice guidelines by the Infectious Diseases Society of America. Clin Infect Dis (2012) 8.56
Sustained reductions in invasive pneumococcal disease in the era of conjugate vaccine. J Infect Dis (2010) 8.37
Linezolid in methicillin-resistant Staphylococcus aureus nosocomial pneumonia: a randomized, controlled study. Clin Infect Dis (2012) 7.97
Effect of introduction of the pneumococcal conjugate vaccine on drug-resistant Streptococcus pneumoniae. N Engl J Med (2006) 7.68
Guidelines for improving entry into and retention in care and antiretroviral adherence for persons with HIV: evidence-based recommendations from an International Association of Physicians in AIDS Care panel. Ann Intern Med (2012) 7.04
Noninvasive positive-pressure ventilation for respiratory failure after extubation. N Engl J Med (2004) 7.03
Infectious Diseases Society of America guidelines for the diagnosis and treatment of asymptomatic bacteriuria in adults. Clin Infect Dis (2005) 6.85
Diagnosis, prevention, and treatment of catheter-associated urinary tract infection in adults: 2009 International Clinical Practice Guidelines from the Infectious Diseases Society of America. Clin Infect Dis (2010) 6.70
U.S. hospitalizations for pneumonia after a decade of pneumococcal vaccination. N Engl J Med (2013) 6.60
Diagnosis and management of complicated intra-abdominal infection in adults and children: guidelines by the Surgical Infection Society and the Infectious Diseases Society of America. Clin Infect Dis (2010) 6.59
Seasonal influenza in adults and children--diagnosis, treatment, chemoprophylaxis, and institutional outbreak management: clinical practice guidelines of the Infectious Diseases Society of America. Clin Infect Dis (2009) 6.52
Assessment of the risk of Ebola virus transmission from bodily fluids and fomites. J Infect Dis (2007) 6.46
Incidence of pneumococcal disease due to non-pneumococcal conjugate vaccine (PCV7) serotypes in the United States during the era of widespread PCV7 vaccination, 1998-2004. J Infect Dis (2007) 6.45
Tiotropium Respimat inhaler and the risk of death in COPD. N Engl J Med (2013) 6.36
Severe community-onset pneumonia in healthy adults caused by methicillin-resistant Staphylococcus aureus carrying the Panton-Valentine leukocidin genes. Clin Infect Dis (2004) 6.13
Community-Acquired Pneumonia Requiring Hospitalization among U.S. Adults. N Engl J Med (2015) 6.04
An Official ATS/ERS/JRS/ALAT Clinical Practice Guideline: Treatment of Idiopathic Pulmonary Fibrosis. An Update of the 2011 Clinical Practice Guideline. Am J Respir Crit Care Med (2015) 6.03
Characteristics and outcomes in adult patients receiving mechanical ventilation: a 28-day international study. JAMA (2002) 6.00
Diagnosis and initial management of nonmalignant diseases related to asbestos. Am J Respir Crit Care Med (2004) 5.56
Guidelines for treatment of candidiasis. Clin Infect Dis (2003) 5.55
Clinical practice guidelines for the management of patients with histoplasmosis: 2007 update by the Infectious Diseases Society of America. Clin Infect Dis (2007) 5.51
Treatment of tuberculosis. MMWR Recomm Rep (2003) 5.41
Outcomes for COPD pharmacological trials: from lung function to biomarkers. Eur Respir J (2008) 5.38
Changing epidemiology of invasive pneumococcal disease among older adults in the era of pediatric pneumococcal conjugate vaccine. JAMA (2005) 5.29
Update of practice guidelines for the management of community-acquired pneumonia in immunocompetent adults. Clin Infect Dis (2003) 5.21
Guidelines for preventing infectious complications among hematopoietic cell transplantation recipients: a global perspective. Biol Blood Marrow Transplant (2009) 5.10
Guidelines for the management of intravascular catheter-related infections. Clin Infect Dis (2001) 4.94
Population snapshot of emergent Streptococcus pneumoniae serotype 19A in the United States, 2005. J Infect Dis (2008) 4.91
Community-acquired pneumonia requiring hospitalization among U.S. children. N Engl J Med (2015) 4.90
Practice guidelines for the management of infectious diarrhea. Clin Infect Dis (2001) 4.49
Practice guidelines for the diagnosis and management of group A streptococcal pharyngitis. Infectious Diseases Society of America. Clin Infect Dis (2002) 4.43
Antimicrobial prophylaxis for surgery: an advisory statement from the National Surgical Infection Prevention Project. Clin Infect Dis (2004) 4.40
Effect of pneumococcal conjugate vaccine on pneumococcal meningitis. N Engl J Med (2009) 4.38
Human disease from influenza A (H5N1), Thailand, 2004. Emerg Infect Dis (2005) 4.27
Multiple-center, randomized, placebo-controlled, double-blind study of the nitric oxide synthase inhibitor 546C88: effect on survival in patients with septic shock. Crit Care Med (2004) 4.24
Clinical practice. Community-acquired pneumonia. N Engl J Med (2014) 4.14
Transmission of the severe acute respiratory syndrome on aircraft. N Engl J Med (2003) 4.09
10 x '20 Progress--development of new drugs active against gram-negative bacilli: an update from the Infectious Diseases Society of America. Clin Infect Dis (2013) 4.07
GOLD 2011 disease severity classification in COPDGene: a prospective cohort study. Lancet Respir Med (2012) 3.98
Coccidioidomycosis. Clin Infect Dis (2005) 3.88
American Thoracic Society/Centers for Disease Control and Prevention/Infectious Diseases Society of America: controlling tuberculosis in the United States. Am J Respir Crit Care Med (2005) 3.82
The management of encephalitis: clinical practice guidelines by the Infectious Diseases Society of America. Clin Infect Dis (2008) 3.79
Postvaccine genetic structure of Streptococcus pneumoniae serotype 19A from children in the United States. J Infect Dis (2005) 3.76
Policy statement on antimicrobial stewardship by the Society for Healthcare Epidemiology of America (SHEA), the Infectious Diseases Society of America (IDSA), and the Pediatric Infectious Diseases Society (PIDS). Infect Control Hosp Epidemiol (2012) 3.76
Risk of bacterial meningitis in children with cochlear implants. N Engl J Med (2003) 3.75
Clinical findings and demographic factors associated with ICU admission in Utah due to novel 2009 influenza A(H1N1) infection. Chest (2009) 3.70
Guidelines for evaluation of new fever in critically ill adult patients: 2008 update from the American College of Critical Care Medicine and the Infectious Diseases Society of America. Crit Care Med (2008) 3.67
Practice guidelines for the diagnosis and management of skin and soft tissue infections: 2014 update by the Infectious Diseases Society of America. Clin Infect Dis (2014) 3.67
Staphylococcus aureus bacteremia: recurrence and the impact of antibiotic treatment in a prospective multicenter study. Medicine (Baltimore) (2003) 3.66
American Thoracic Society/European Respiratory Society statement: standards for the diagnosis and management of individuals with alpha-1 antitrypsin deficiency. Am J Respir Crit Care Med (2003) 3.59
Controlling tuberculosis in the United States. Recommendations from the American Thoracic Society, CDC, and the Infectious Diseases Society of America. MMWR Recomm Rep (2005) 3.54
Geographic diversity and temporal trends of antimicrobial resistance in Streptococcus pneumoniae in the United States. Nat Med (2003) 3.54
The future of antibiotics and resistance. N Engl J Med (2013) 3.47
Evolution of mechanical ventilation in response to clinical research. Am J Respir Crit Care Med (2007) 3.45
Accuracy of administrative data for identifying patients with pneumonia. Am J Med Qual (2005) 3.43
Clinical practice guideline for the diagnosis and management of group A streptococcal pharyngitis: 2012 update by the Infectious Diseases Society of America. Clin Infect Dis (2012) 3.41
Ventilator settings as a risk factor for acute respiratory distress syndrome in mechanically ventilated patients. Intensive Care Med (2005) 3.32
An outbreak of conjunctivitis due to atypical Streptococcus pneumoniae. N Engl J Med (2003) 3.32
Timing of antibiotic administration and outcomes for Medicare patients hospitalized with community-acquired pneumonia. Arch Intern Med (2004) 3.30
2012 Infectious Diseases Society of America clinical practice guideline for the diagnosis and treatment of diabetic foot infections. Clin Infect Dis (2012) 3.22
Telavancin versus vancomycin for hospital-acquired pneumonia due to gram-positive pathogens. Clin Infect Dis (2011) 3.20
The Berlin definition of ARDS: an expanded rationale, justification, and supplementary material. Intensive Care Med (2012) 3.18
Principles of appropriate antibiotic use for acute rhinosinusitis in adults: background. Ann Intern Med (2001) 3.15