Published in Thorax on January 20, 2011
Differences between asthmatics and nonasthmatics hospitalised with influenza A infection. Eur Respir J (2012) 1.44
A distinct influenza infection signature in the blood transcriptome of patients with severe community-acquired pneumonia. Crit Care (2012) 1.27
H1N1-infected Patients in ICU and Their Clinical Outcome. N Am J Med Sci (2012) 1.02
Pre-admission statin use and in-hospital severity of 2009 pandemic influenza A(H1N1) disease. PLoS One (2011) 0.91
Sociodemographic factors and clinical conditions associated to hospitalization in influenza A (H1N1) 2009 virus infected patients in Spain, 2009-2010. PLoS One (2012) 0.89
General Characteristics and Prognostic Factors of Pneumonia Cases Developed During Pandemic (H1N1) Influenza-A Virus Infection in Turkey. Balkan Med J (2013) 0.88
Impact of neuraminidase inhibitors on influenza A(H1N1)pdm09-related pneumonia: an individual participant data meta-analysis. Influenza Other Respir Viruses (2016) 0.84
Predicting the unpredictable: is it possible clinically to separate H1N1 from non-H1N1 community-acquired pneumonia? Thorax (2011) 0.79
Influenza infection screening tools fail to accurately predict influenza status for patients during pandemic H1N1 influenza season. Can Respir J (2013) 0.79
H1N1 influenza pneumonia and bacterial coinfection. Thorax (2011) 0.76
Emergence of a novel swine-origin influenza A (H1N1) virus in humans. N Engl J Med (2009) 42.75
Infectious Diseases Society of America/American Thoracic Society consensus guidelines on the management of community-acquired pneumonia in adults. Clin Infect Dis (2007) 24.91
A prediction rule to identify low-risk patients with community-acquired pneumonia. N Engl J Med (1997) 24.87
Hospitalized patients with 2009 H1N1 influenza in the United States, April-June 2009. N Engl J Med (2009) 16.13
Cross-reactive antibody responses to the 2009 pandemic H1N1 influenza virus. N Engl J Med (2009) 15.02
Pneumonia and respiratory failure from swine-origin influenza A (H1N1) in Mexico. N Engl J Med (2009) 14.48
Critically ill patients with 2009 influenza A(H1N1) infection in Canada. JAMA (2009) 13.00
Incidence of 2009 pandemic influenza A H1N1 infection in England: a cross-sectional serological study. Lancet (2010) 12.43
Predominant role of bacterial pneumonia as a cause of death in pandemic influenza: implications for pandemic influenza preparedness. J Infect Dis (2008) 11.01
Critical care services and 2009 H1N1 influenza in Australia and New Zealand. N Engl J Med (2009) 10.60
Factors associated with death or hospitalization due to pandemic 2009 influenza A(H1N1) infection in California. JAMA (2009) 10.13
Clinical aspects of pandemic 2009 influenza A (H1N1) virus infection. N Engl J Med (2010) 9.90
Defining community acquired pneumonia severity on presentation to hospital: an international derivation and validation study. Thorax (2003) 9.54
Surviving Sepsis Campaign: international guidelines for management of severe sepsis and septic shock: 2008. Intensive Care Med (2007) 8.33
Outbreak of swine-origin influenza A (H1N1) virus infection - Mexico, March-April 2009. MMWR Morb Mortal Wkly Rep (2009) 8.03
Clinical features of the initial cases of 2009 pandemic influenza A (H1N1) virus infection in China. N Engl J Med (2009) 6.45
Infection and death from influenza A H1N1 virus in Mexico: a retrospective analysis. Lancet (2009) 6.05
Bacterial coinfections in lung tissue specimens from fatal cases of 2009 pandemic influenza A (H1N1) - United States, May-August 2009. MMWR Morb Mortal Wkly Rep (2009) 5.25
BTS guidelines for the management of community acquired pneumonia in adults: update 2009. Thorax (2009) 5.23
Prospective study of the aetiology and outcome of pneumonia in the community. Lancet (1987) 4.53
Hospital study of adult community-acquired pneumonia. Lancet (1982) 4.52
Intensive care adult patients with severe respiratory failure caused by Influenza A (H1N1)v in Spain. Crit Care (2009) 4.45
Pulmonary pathologic findings of fatal 2009 pandemic influenza A/H1N1 viral infections. Arch Pathol Lab Med (2010) 3.91
Study of community acquired pneumonia aetiology (SCAPA) in adults admitted to hospital: implications for management guidelines. Thorax (2001) 3.38
Incidence and characteristics of viral community-acquired pneumonia in adults. Thorax (2007) 3.34
2009 pandemic influenza A (H1N1): pathology and pathogenesis of 100 fatal cases in the United States. Am J Pathol (2010) 3.32
Complications of viral influenza. Am J Med (2008) 3.28
Australia's winter with the 2009 pandemic influenza A (H1N1) virus. N Engl J Med (2009) 2.60
Improved diagnosis of the etiology of community-acquired pneumonia with real-time polymerase chain reaction. Clin Infect Dis (2005) 2.54
Risk factors for hospitalisation and poor outcome with pandemic A/H1N1 influenza: United Kingdom first wave (May-September 2009). Thorax (2010) 2.36
Viral infection in adults hospitalized with community-acquired pneumonia: prevalence, pathogens, and presentation. Chest (2008) 2.26
Severe human influenza infections in Thailand: oseltamivir treatment and risk factors for fatal outcome. PLoS One (2009) 2.20
Cytokine profiles induced by the novel swine-origin influenza A/H1N1 virus: implications for treatment strategies. J Infect Dis (2010) 1.82
Outcomes of adults hospitalised with severe influenza. Thorax (2010) 1.80
Pneumococcal pneumonia and influenza: a deadly combination. Vaccine (2009) 1.78
Immunity to pre-1950 H1N1 influenza viruses confers cross-protection against the pandemic swine-origin 2009 A (H1N1) influenza virus. J Immunol (2010) 1.74
Influenza A(H1N1)v in Germany: the first 10,000 cases. Euro Surveill (2009) 1.68
Clinical practice guideline for the evaluation of fever and infection in older adult residents of long-term care facilities: 2008 update by the Infectious Diseases Society of America. Clin Infect Dis (2009) 1.67
Hypercytokinemia and hyperactivation of phospho-p38 mitogen-activated protein kinase in severe human influenza A virus infection. Clin Infect Dis (2007) 1.57
Effect of the novel influenza A (H1N1) virus in the human immune system. PLoS One (2009) 1.45
Imaging of pneumonia: trends and algorithms. Eur Respir J (2001) 1.41
The role of viruses in the aetiology of community-acquired pneumonia in adults. Antivir Ther (2006) 1.28
Autopsy findings in eight patients with fatal H1N1 influenza. Am J Clin Pathol (2010) 1.25
A trivalent virus-like particle vaccine elicits protective immune responses against seasonal influenza strains in mice and ferrets. PLoS One (2009) 1.13
Responding to pandemic (H1N1) 2009 influenza: the role of oseltamivir. J Antimicrob Chemother (2010) 1.05
Does early review by a respiratory physician lead to a shorter length of stay for patients with non-severe community-acquired pneumonia? Thorax (2009) 1.00
Characteristics of hospitalised patients with 2009 H1N1 influenza in Chile. Eur Respir J (2010) 0.98
Clinical features, treatments and prognosis of the initial cases of pandemic influenza H1N1 2009 virus infection in Shanghai China. QJM (2010) 0.96
Pandemic influenza A (H1N1) 2009: chest radiographic findings from 147 proven cases in the Montreal area. Can Assoc Radiol J (2010) 0.79
Cytokine storm in a phase 1 trial of the anti-CD28 monoclonal antibody TGN1412. N Engl J Med (2006) 15.04
Clinical aspects of pandemic 2009 influenza A (H1N1) virus infection. N Engl J Med (2010) 9.90
Evaluation of Convalescent Plasma for Ebola Virus Disease in Guinea. N Engl J Med (2016) 6.22
Trial of 2009 influenza A (H1N1) monovalent MF59-adjuvanted vaccine. N Engl J Med (2009) 5.73
IFITM3 restricts the morbidity and mortality associated with influenza. Nature (2012) 4.66
Referral to an extracorporeal membrane oxygenation center and mortality among patients with severe 2009 influenza A(H1N1). JAMA (2011) 4.24
Pneumonia: update on diagnosis and management. BMJ (2006) 3.69
Cross-reactivity to highly pathogenic avian influenza H5N1 viruses after vaccination with nonadjuvanted and MF59-adjuvanted influenza A/Duck/Singapore/97 (H5N3) vaccine: a potential priming strategy. J Infect Dis (2005) 3.20
Stockpiling prepandemic influenza vaccines: a new cornerstone of pandemic preparedness plans. Lancet Infect Dis (2008) 2.93
Single versus combination antibiotic therapy in adults hospitalised with community acquired pneumonia. Thorax (2012) 2.81
Cochrane re-arranged: support for policies to vaccinate elderly people against influenza. Vaccine (2013) 2.69
Sudden acute respiratory syndrome. BMJ (2003) 2.68
Immunogenicity and safety of a two-dose schedule of whole-virion and AS03A-adjuvanted 2009 influenza A (H1N1) vaccines: a randomised, multicentre, age-stratified, head-to-head trial. Lancet Infect Dis (2010) 2.67
Impact of neuraminidase inhibitor treatment on outcomes of public health importance during the 2009-2010 influenza A(H1N1) pandemic: a systematic review and meta-analysis in hospitalized patients. J Infect Dis (2012) 2.67
Randomised trials of 6% tetrastarch (hydroxyethyl starch 130/0.4 or 0.42) for severe sepsis reporting mortality: systematic review and meta-analysis. Intensive Care Med (2013) 2.42
Antigenically distinct MF59-adjuvanted vaccine to boost immunity to H5N1. N Engl J Med (2008) 2.21
Low serum mannose-binding lectin level increases the risk of death due to pneumococcal infection. Clin Infect Dis (2008) 2.20
Diagnostic and prognostic implications of endotoxemia in critical illness: results of the MEDIC study. J Infect Dis (2004) 2.17
Serotype prevalence in adults hospitalised with pneumococcal non-invasive community-acquired pneumonia. Thorax (2012) 2.17
Evolution of epitope-specific memory CD4(+) T cells after clearance of hepatitis C virus. J Immunol (2002) 2.13
Moxifloxacin monotherapy is effective in hospitalized patients with community-acquired pneumonia: the MOTIV study--a randomized clinical trial. Clin Infect Dis (2008) 2.09
Boosting immunity to influenza H5N1 with MF59-adjuvanted H5N3 A/Duck/Singapore/97 vaccine in a primed human population. Vaccine (2003) 2.04
Identification of in vivo-expressed antigens of Staphylococcus aureus and their use in vaccinations for protection against nasal carriage. J Infect Dis (2006) 1.99
Severity of meningococcal disease associated with genomic bacterial load. Clin Infect Dis (2009) 1.92
The effectiveness of convalescent plasma and hyperimmune immunoglobulin for the treatment of severe acute respiratory infections of viral etiology: a systematic review and exploratory meta-analysis. J Infect Dis (2014) 1.88
The Early Transmission Dynamics of H1N1pdm Influenza in the United Kingdom. PLoS Curr (2009) 1.87
Spread of hepatitis C virus among European injection drug users infected with HIV: a phylogenetic analysis. J Infect Dis (2004) 1.85
Pneumococcal disease in HIV-infected Malawian adults: acute mortality and long-term survival. AIDS (2002) 1.79
An exploration of social and economic outcome and associated health-related quality of life after critical illness in general intensive care unit survivors: a 12-month follow-up study. Crit Care (2013) 1.78
Community-acquired pneumonia mortality: a potential link to antibiotic prescribing trends in general practice. Respir Med (2004) 1.76
Safety and antigenicity of whole virus and subunit influenza A/Hong Kong/1073/99 (H9N2) vaccine in healthy adults: phase I randomised trial. Lancet (2003) 1.75
Methylation status of a single CpG site in the IL6 promoter is related to IL6 messenger RNA levels and rheumatoid arthritis. Arthritis Rheum (2008) 1.73
The interaction of vasopressin and corticosteroids in septic shock: a pilot randomized controlled trial. Crit Care Med (2014) 1.69
Confronting the avian influenza threat: vaccine development for a potential pandemic. Lancet Infect Dis (2004) 1.66
Age-related loss of CpG methylation in the tumour necrosis factor promoter. Cytokine (2011) 1.58
Toll-like receptors in health and disease: complex questions remain. J Immunol (2003) 1.57
Attenuated Bordetella pertussis vaccine protects against respiratory syncytial virus disease via an IL-17-dependent mechanism. Am J Respir Crit Care Med (2014) 1.56
Effectiveness of H1N1 vaccine for the prevention of pandemic influenza in Scotland, UK: a retrospective observational cohort study. Lancet Infect Dis (2012) 1.53
Flavohemoglobin Hmp protects Salmonella enterica serovar typhimurium from nitric oxide-related killing by human macrophages. Infect Immun (2002) 1.53
Genetic polymorphism of the binding domain of surfactant protein-A2 increases susceptibility to meningococcal disease. Clin Infect Dis (2006) 1.51
Purified protein derivative-activated type 1 cytokine-producing CD4+ T lymphocytes in the lung: a characteristic feature of active pulmonary and nonpulmonary tuberculosis. J Infect Dis (2002) 1.51
Nitric oxide metabolism in Neisseria meningitidis. J Bacteriol (2002) 1.49
Open source clinical science for emerging infections. Lancet Infect Dis (2014) 1.47
Effectiveness of seasonal influenza vaccine for adults and children in preventing laboratory-confirmed influenza in primary care in the United Kingdom: 2015/16 end-of-season results. Euro Surveill (2016) 1.46
What is the role of pulse oximetry in the assessment of patients with community-acquired pneumonia in primary care? Prim Care Respir J (2010) 1.46
Differences between asthmatics and nonasthmatics hospitalised with influenza A infection. Eur Respir J (2012) 1.44
Management of meningitis. Clin Med (2005) 1.43
Dynamic changes in Mcl-1 expression regulate macrophage viability or commitment to apoptosis during bacterial clearance. J Clin Invest (2005) 1.42
Nitric oxide in chemostat-cultured Escherichia coli is sensed by Fnr and other global regulators: unaltered methionine biosynthesis indicates lack of S nitrosation. J Bacteriol (2006) 1.42
Bird flu and pandemic flu. BMJ (2005) 1.41
Predictors of clinical outcome in a national hospitalised cohort across both waves of the influenza A/H1N1 pandemic 2009-2010 in the UK. Thorax (2012) 1.40
Pharmacological Therapy for the Prevention and Treatment of Weakness After Critical Illness: A Systematic Review. Crit Care Med (2016) 1.38
Nitric oxide detoxification systems enhance survival of Neisseria meningitidis in human macrophages and in nasopharyngeal mucosa. Infect Immun (2005) 1.37
The "Resus:Station": the use of clinical simulations in a randomised crossover study to evaluate a novel resuscitation trolley. Resuscitation (2012) 1.37
Strategies to increase influenza vaccination rates: outcomes of a nationwide cross-sectional survey of UK general practice. BMJ Open (2012) 1.37
Primary care summary of the British Thoracic Society Guidelines for the management of community acquired pneumonia in adults: 2009 update. Endorsed by the Royal College of General Practitioners and the Primary Care Respiratory Society UK. Prim Care Respir J (2010) 1.36
Nitric oxide levels regulate macrophage commitment to apoptosis or necrosis during pneumococcal infection. FASEB J (2004) 1.33
Interaction of the Salmonella typhimurium transcription and virulence factor SlyA with target DNA and identification of members of the SlyA regulon. J Biol Chem (2002) 1.32
Bacterial pneumonia and pandemic influenza planning. Emerg Infect Dis (2008) 1.30
Streptococcus pneumoniae-associated human macrophage apoptosis after bacterial internalization via complement and Fcgamma receptors correlates with intracellular bacterial load. J Infect Dis (2003) 1.28
Mannose-binding lectin polymorphisms in severe sepsis: relationship to levels, incidence, and outcome. Shock (2006) 1.26
CD8+ T cell responses in bronchoalveolar lavage fluid and peripheral blood mononuclear cells of infants with severe primary respiratory syncytial virus infections. J Immunol (2007) 1.26
Rehabilitation after critical illness: summary of NICE guidance. BMJ (2009) 1.25
Clinical review: Intensive care follow-up--what has it told us? Crit Care (2002) 1.25
IL-10 regulates viral lung immunopathology during acute respiratory syncytial virus infection in mice. PLoS One (2012) 1.23
Microbes and mucosal immune responses in asthma. Lancet (2013) 1.20
Use of a human influenza challenge model to assess person-to-person transmission: proof-of-concept study. J Infect Dis (2011) 1.20
Influenza vaccination coverage rates in the UK: a comparison of two monitoring methods during the 2002-2003 and 2003-2004 seasons. Public Health (2006) 1.20
Pulmonary vascular and right ventricular dysfunction in adult critical care: current and emerging options for management: a systematic literature review. Crit Care (2010) 1.18
Invasion by Neisseria meningitidis varies widely between clones and among nasopharyngeal mucosae derived from adult human hosts. Microbiology (2002) 1.17
Effectiveness of seasonal influenza vaccine in preventing laboratory-confirmed influenza in primary care in the United Kingdom: 2014/15 end of season results. Euro Surveill (2015) 1.17
Regulation of denitrification genes in Neisseria meningitidis by nitric oxide and the repressor NsrR. J Bacteriol (2006) 1.14
Global assessment of resistance to neuraminidase inhibitors, 2008-2011: the Influenza Resistance Information Study (IRIS). Clin Infect Dis (2013) 1.12
Neisseria meningitidis lactate permease is required for nasopharyngeal colonization. Infect Immun (2005) 1.11