Published in J Biol Chem on February 08, 2007
The mechanism of double-strand DNA break repair by the nonhomologous DNA end-joining pathway. Annu Rev Biochem (2010) 9.80
Human HDAC1 and HDAC2 function in the DNA-damage response to promote DNA nonhomologous end-joining. Nat Struct Mol Biol (2010) 3.27
Repair of double-strand breaks by end joining. Cold Spring Harb Perspect Biol (2013) 1.58
XRCC4 protein interactions with XRCC4-like factor (XLF) create an extended grooved scaffold for DNA ligation and double strand break repair. J Biol Chem (2011) 1.48
A new method for high-resolution imaging of Ku foci to decipher mechanisms of DNA double-strand break repair. J Cell Biol (2013) 1.29
The miR-99 family regulates the DNA damage response through its target SNF2H. Oncogene (2012) 1.24
Histone H1 functions as a stimulatory factor in backup pathways of NHEJ. Nucleic Acids Res (2008) 1.10
Mutually exclusive binding of telomerase RNA and DNA by Ku alters telomerase recruitment model. Cell (2012) 1.08
Coordination of DNA-PK activation and nuclease processing of DNA termini in NHEJ. Antioxid Redox Signal (2010) 0.90
The tumor marker human placental protein 11 is an endoribonuclease. J Biol Chem (2008) 0.87
Evidence for an inositol hexakisphosphate-dependent role for Ku in mammalian nonhomologous end joining that is independent of its role in the DNA-dependent protein kinase. Nucleic Acids Res (2008) 0.83
Resolution of complex ends by Nonhomologous end joining - better to be lucky than good? Genome Integr (2012) 0.76
C-terminal region of bacterial Ku controls DNA bridging, DNA threading and recruitment of DNA ligase D for double strand breaks repair. Nucleic Acids Res (2016) 0.76
The structure of ends determines the pathway choice and Mre11 nuclease dependency of DNA double-strand break repair. Nucleic Acids Res (2016) 0.75
Yeast HMO1: Linker Histone Reinvented. Microbiol Mol Biol Rev (2016) 0.75
Protection of Arabidopsis blunt-ended telomeres is mediated by a physical association with the Ku heterodimer. Plant Cell (2017) 0.75
A gradient of template dependence defines distinct biological roles for family X polymerases in nonhomologous end joining. Mol Cell (2005) 3.68
Autophosphorylation of the catalytic subunit of the DNA-dependent protein kinase is required for efficient end processing during DNA double-strand break repair. Mol Cell Biol (2003) 2.74
Polymerase mu is a DNA-directed DNA/RNA polymerase. Mol Cell Biol (2003) 2.26
Association of DNA polymerase mu (pol mu) with Ku and ligase IV: role for pol mu in end-joining double-strand break repair. Mol Cell Biol (2002) 2.25
The DNA-dependent protein kinase: the director at the end. Immunol Rev (2004) 2.20
Non-homologous end joining requires that the DNA-PK complex undergo an autophosphorylation-dependent rearrangement at DNA ends. J Biol Chem (2004) 1.76
Ku is a 5'-dRP/AP lyase that excises nucleotide damage near broken ends. Nature (2010) 1.74
Structural insight into the substrate specificity of DNA Polymerase mu. Nat Struct Mol Biol (2006) 1.64
Werner protein is a target of DNA-dependent protein kinase in vivo and in vitro, and its catalytic activities are regulated by phosphorylation. J Biol Chem (2002) 1.56
Sensing of intermediates in V(D)J recombination by ATM. Genes Dev (2002) 1.42
Genomic instability due to V(D)J recombination-associated transposition. Genes Dev (2006) 1.29
End-bridging is required for pol mu to efficiently promote repair of noncomplementary ends by nonhomologous end joining. Nucleic Acids Res (2008) 1.24
Ku heterodimer binds to both ends of the Werner protein and functional interaction occurs at the Werner N-terminus. Nucleic Acids Res (2002) 1.22
Mechanism of repair of 5'-topoisomerase II-DNA adducts by mammalian tyrosyl-DNA phosphodiesterase 2. Nat Struct Mol Biol (2012) 1.21
Template strand scrunching during DNA gap repair synthesis by human polymerase lambda. Nat Struct Mol Biol (2009) 1.19
Dual modes of interaction between XRCC4 and polynucleotide kinase/phosphatase: implications for nonhomologous end joining. J Biol Chem (2010) 1.14
Tyrosyl-DNA phosphodiesterase and the repair of 3'-phosphoglycolate-terminated DNA double-strand breaks. DNA Repair (Amst) (2009) 1.13
Histone 3 lysine 4 methylation during the pre-B to immature B-cell transition. Nucleic Acids Res (2004) 1.11
Sibling rivalry: competition between Pol X family members in V(D)J recombination and general double strand break repair. Immunol Rev (2004) 1.10
Phosphorylation in the serine/threonine 2609-2647 cluster promotes but is not essential for DNA-dependent protein kinase-mediated nonhomologous end joining in human whole-cell extracts. Nucleic Acids Res (2007) 1.04
Specificity of the dRP/AP lyase of Ku promotes nonhomologous end joining (NHEJ) fidelity at damaged ends. J Biol Chem (2012) 0.97
WRN Exonuclease activity is blocked by specific oxidatively induced base lesions positioned in either DNA strand. Nucleic Acids Res (2008) 0.91
A comparison of BRCT domains involved in nonhomologous end-joining: introducing the solution structure of the BRCT domain of polymerase lambda. DNA Repair (Amst) (2008) 0.91
Translesion synthesis past platinum DNA adducts by human DNA polymerase mu. Biochemistry (2003) 0.88
Solution structure of polymerase mu's BRCT Domain reveals an element essential for its role in nonhomologous end joining. Biochemistry (2007) 0.87
Activity of ribonucleotide reductase helps determine how cells repair DNA double strand breaks. DNA Repair (Amst) (2009) 0.87
Trimming of damaged 3' overhangs of DNA double-strand breaks by the Metnase and Artemis endonucleases. DNA Repair (Amst) (2013) 0.82
Resolution of complex ends by Nonhomologous end joining - better to be lucky than good? Genome Integr (2012) 0.76