Published in PLoS Genet on December 18, 2006
Genomic imprinting: the emergence of an epigenetic paradigm. Nat Rev Genet (2011) 3.10
RNA-based gene duplication: mechanistic and evolutionary insights. Nat Rev Genet (2009) 2.91
Transcription is required for establishment of germline methylation marks at imprinted genes. Genes Dev (2009) 2.76
Alternative cleavage and polyadenylation: extent, regulation and function. Nat Rev Genet (2013) 2.37
The function of non-coding RNAs in genomic imprinting. Development (2009) 2.21
Regulation of alternative polyadenylation by genomic imprinting. Genes Dev (2008) 1.89
A tripartite paternally methylated region within the Gpr1-Zdbf2 imprinted domain on mouse chromosome 1 identified by meDIP-on-chip. Nucleic Acids Res (2010) 1.83
The human retinoblastoma gene is imprinted. PLoS Genet (2009) 1.63
New insights into establishment and maintenance of DNA methylation imprints in mammals. Philos Trans R Soc Lond B Biol Sci (2013) 1.49
A novel approach identifies new differentially methylated regions (DMRs) associated with imprinted genes. Genome Res (2011) 1.45
The parental non-equivalence of imprinting control regions during mammalian development and evolution. PLoS Genet (2010) 1.41
The origin and evolution of genomic imprinting and viviparity in mammals. Philos Trans R Soc Lond B Biol Sci (2013) 1.27
A survey for novel imprinted genes in the mouse placenta by mRNA-seq. Genetics (2011) 1.24
A survey of tissue-specific genomic imprinting in mammals. Mol Genet Genomics (2012) 1.19
Chromosome-wide analysis of parental allele-specific chromatin and DNA methylation. Mol Cell Biol (2011) 1.11
ATP-dependent chromatin remodeling by Cockayne syndrome protein B and NAP1-like histone chaperones is required for efficient transcription-coupled DNA repair. PLoS Genet (2013) 1.05
Evaluation of allelic expression of imprinted genes in adult human blood. PLoS One (2010) 1.05
Epigenetic control of alternative mRNA processing at the imprinted Herc3/Nap1l5 locus. Nucleic Acids Res (2012) 1.04
Successful computational prediction of novel imprinted genes from epigenomic features. Mol Cell Biol (2010) 1.00
Characterization of conserved and nonconserved imprinted genes in swine. Biol Reprod (2009) 0.98
Allele-specific demethylation at an imprinted mammalian promoter. Nucleic Acids Res (2007) 0.96
Retrotransposition and genomic imprinting. Brief Funct Genomics (2010) 0.95
The specification of imprints in mammals. Heredity (Edinb) (2014) 0.93
Novel retrotransposed imprinted locus identified at human 6p25. Nucleic Acids Res (2011) 0.90
Discovery of a novel imprinted gene by transcriptional analysis of parthenogenetic embryonic stem cells. Hum Reprod (2010) 0.90
Recent acquisition of imprinting at the rodent Sfmbt2 locus correlates with insertion of a large block of miRNAs. BMC Genomics (2011) 0.90
Divergence of imprinted genes during mammalian evolution. BMC Evol Biol (2010) 0.89
Comparative analysis of sequence characteristics of imprinted genes in human, mouse, and cattle. Mamm Genome (2007) 0.89
Human imprinted retrogenes exhibit non-canonical imprint chromatin signatures and reside in non-imprinted host genes. Nucleic Acids Res (2011) 0.89
The evolution of mammalian genomic imprinting was accompanied by the acquisition of novel CpG islands. Genome Biol Evol (2011) 0.88
Unwitting hosts fall victim to imprinting. Epigenetics (2008) 0.87
Epigenetics and ncRNAs in brain function and disease: mechanisms and prospects for therapy. Neurotherapeutics (2013) 0.85
Genome-wide and parental allele-specific analysis of CTCF and cohesin DNA binding in mouse brain reveals a tissue-specific binding pattern and an association with imprinted differentially methylated regions. Genome Res (2013) 0.84
Human PPP1R26P1 functions as cis-repressive element in mouse Rb1. PLoS One (2013) 0.83
A case-by-case evolutionary analysis of four imprinted retrogenes. Evolution (2011) 0.83
An extended domain of Kcnq1ot1 silencing revealed by an imprinted fluorescent reporter. Mol Cell Biol (2011) 0.82
An imprinted GFP insertion reveals long-range epigenetic regulation in embryonic lineages. Dev Biol (2009) 0.82
Evolutionary origin and methylation status of human intronic CpG islands that are not present in mouse. Genome Biol Evol (2014) 0.81
Germline and somatic imprinting in the nonhuman primate highlights species differences in oocyte methylation. Genome Res (2015) 0.79
Short interspersed element (SINE) depletion and long interspersed element (LINE) abundance are not features universally required for imprinting. PLoS One (2011) 0.79
Allelome.PRO, a pipeline to define allele-specific genomic features from high-throughput sequencing data. Nucleic Acids Res (2015) 0.77
Mammalian-specific genomic functions: Newly acquired traits generated by genomic imprinting and LTR retrotransposon-derived genes in mammals. Proc Jpn Acad Ser B Phys Biol Sci (2015) 0.77
Imprinted chromatin around DIRAS3 regulates alternative splicing of GNG12-AS1, a long noncoding RNA. Am J Hum Genet (2013) 0.77
Known unknowns for allele-specific expression and genomic imprinting effects. F1000Prime Rep (2014) 0.76
Genome-wide methylation analysis of retrocopy-associated CpG islands and their genomic environment. Epigenetics (2016) 0.75
Protein-Coding Genes' Retrocopies and Their Functions. Viruses (2017) 0.75
A Mouse Model for Imprinting of the Human Retinoblastoma Gene. PLoS One (2015) 0.75
The human genome browser at UCSC. Genome Res (2002) 168.23
BLAT--the BLAST-like alignment tool. Genome Res (2002) 126.78
Human-mouse alignments with BLASTZ. Genome Res (2003) 35.49
Cytosine methylation and the ecology of intragenomic parasites. Trends Genet (1997) 13.66
Role for DNA methylation in genomic imprinting. Nature (1993) 12.65
Mobile elements: drivers of genome evolution. Science (2004) 11.78
Meiotic catastrophe and retrotransposon reactivation in male germ cells lacking Dnmt3L. Nature (2004) 7.57
Transcription of IAP endogenous retroviruses is constrained by cytosine methylation. Nat Genet (1998) 7.49
Dnmt3L and the establishment of maternal genomic imprints. Science (2001) 7.42
Double-stranded RNA-mediated silencing of genomic tandem repeats and transposable elements in the D. melanogaster germline. Curr Biol (2001) 7.06
Human LINE retrotransposons generate processed pseudogenes. Nat Genet (2000) 6.64
High-resolution genomic profiles of human lung cancer. Proc Natl Acad Sci U S A (2005) 6.52
The origin of new genes: glimpses from the young and old. Nat Rev Genet (2003) 6.14
A census of mammalian imprinting. Trends Genet (2005) 4.84
Identification of signal peptide peptidase, a presenilin-type aspartic protease. Science (2002) 4.39
Asymmetric regulation of imprinting on the maternal and paternal chromosomes at the Dlk1-Gtl2 imprinted cluster on mouse chromosome 12. Nat Genet (2003) 4.25
A modified and improved method for bisulphite based cytosine methylation analysis. Nucleic Acids Res (1996) 4.16
Evolutionary fate of retroposed gene copies in the human genome. Proc Natl Acad Sci U S A (2006) 4.03
Extensive gene traffic on the mammalian X chromosome. Science (2004) 3.89
Retroposed elements as archives for the evolutionary history of placental mammals. PLoS Biol (2006) 3.42
Methylation dynamics of imprinted genes in mouse germ cells. Genomics (2002) 3.19
RIP: the evolutionary cost of genome defense. Trends Genet (2004) 3.13
Human testis-specific PGK gene lacks introns and possesses characteristics of a processed gene. Nature (1987) 3.04
Maternally transmitted histocompatibility antigen of mice: a hydrophobic peptide of a mitochondrially encoded protein. Cell (1990) 2.64
Epigenetic analysis of the Dlk1-Gtl2 imprinted domain on mouse chromosome 12: implications for imprinting control from comparison with Igf2-H19. Hum Mol Genet (2002) 2.33
Genomic imprinting: intricacies of epigenetic regulation in clusters. Annu Rev Cell Dev Biol (2003) 2.26
Methylation and imprinting: from host defense to gene regulation? Science (1993) 2.18
A mouse model for Prader-Willi syndrome imprinting-centre mutations. Nat Genet (1998) 2.16
Short interspersed transposable elements (SINEs) are excluded from imprinted regions in the human genome. Proc Natl Acad Sci U S A (2001) 2.14
Increased gene copy numbers at chromosome 20q are frequent in both squamous cell carcinomas and adenocarcinomas of the cervix. J Pathol (2006) 2.02
Intralocus sexual conflict can drive the evolution of genomic imprinting. Genetics (2004) 1.83
Identification of novel imprinted genes in a genome-wide screen for maternal methylation. Genome Res (2003) 1.67
An X-to-autosome retrogene is required for spermatogenesis in mice. Nat Genet (2004) 1.63
Identification of a large novel imprinted gene cluster on mouse proximal chromosome 6. Genome Res (2003) 1.61
Alu repeated DNAs are differentially methylated in primate germ cells. Nucleic Acids Res (1994) 1.58
X chromosomes, retrogenes and their role in male reproduction. Trends Endocrinol Metab (2004) 1.52
The mouse Murr1 gene is imprinted in the adult brain, presumably due to transcriptional interference by the antisense-oriented U2af1-rs1 gene. Mol Cell Biol (2004) 1.40
A novel variant of Inpp5f is imprinted in brain, and its expression is correlated with differential methylation of an internal CpG island. Mol Cell Biol (2005) 1.32
Tandem repeats in the CpG islands of imprinted genes. Genomics (2006) 1.31
Mouse U2af1-rs1 is a neomorphic imprinted gene. Mol Cell Biol (1997) 1.27
Homology-dependent gene silencing and host defense in plants. Adv Genet (2002) 1.18
A small family of sushi-class retrotransposon-derived genes in mammals and their relation to genomic imprinting. J Mol Evol (2005) 1.14
Homology-dependent methylation in primate repetitive DNA. Proc Natl Acad Sci U S A (2005) 1.13
Retrotransposed genes such as Frat3 in the mouse Chromosome 7C Prader-Willi syndrome region acquire the imprinted status of their insertion site. Mamm Genome (2001) 1.10
Host defenses to transposable elements and the evolution of genomic imprinting. Cytogenet Genome Res (2005) 1.09
Minors held by majors: the H13 minor histocompatibility locus defined as a peptide/MHC class I complex. Immunity (1997) 1.08
Two functional X chromosomes in human fetal oocytes. Exp Cell Res (1973) 1.06
The potential role of gene duplications in the evolution of imprinting mechanisms. Hum Mol Genet (2003) 1.06
A novel candidate oncogene, MCT-1, is involved in cell cycle progression. Cancer Res (1998) 1.06
Increased G1 cyclin/cdk activity in cells overexpressing the candidate oncogene, MCT-1. J Cell Biochem (1999) 0.92
Aberrant methylation of an imprinted gene U2af1-rs1(SP2) caused by its own transgene. J Biol Chem (1997) 0.91
Expression of the candidate MCT-1 oncogene in B- and T-cell lymphoid malignancies. Blood (2003) 0.89
Identification of the rat maternally transmitted minor histocompatibility antigen. J Immunol (1997) 0.85
Histocompatibility genes of mice. VII. H-13, a new histocompatibility locus in the fifth linkage group. Transplantation (1967) 0.82
Sequence variants in the autophagy gene IRGM and multiple other replicating loci contribute to Crohn's disease susceptibility. Nat Genet (2007) 13.74
Mutation of the RAD51C gene in a Fanconi anemia-like disorder. Nat Genet (2010) 3.57
Nesprin-1 and -2 are involved in the pathogenesis of Emery Dreifuss muscular dystrophy and are critical for nuclear envelope integrity. Hum Mol Genet (2007) 3.26
Human chromosome 7: DNA sequence and biology. Science (2003) 3.02
Human MX2 is an interferon-induced post-entry inhibitor of HIV-1 infection. Nature (2013) 2.79
Multiple congenital melanocytic nevi and neurocutaneous melanosis are caused by postzygotic mutations in codon 61 of NRAS. J Invest Dermatol (2013) 2.74
Nesprin-2 is a multi-isomeric protein that binds lamin and emerin at the nuclear envelope and forms a subcellular network in skeletal muscle. J Cell Sci (2005) 2.47
Maternal activating KIRs protect against human reproductive failure mediated by fetal HLA-C2. J Clin Invest (2010) 2.19
Genetics of cleft lip and palate: syndromic genes contribute to the incidence of non-syndromic clefts. Hum Mol Genet (2004) 2.18
A DNA methylation fingerprint of 1628 human samples. Genome Res (2011) 2.16
Multiplex ligation-dependent probe amplification using a completely synthetic probe set. Biotechniques (2004) 2.04
Genomic imprinting in mammals: emerging themes and established theories. PLoS Genet (2006) 1.99
The nesprins are giant actin-binding proteins, orthologous to Drosophila melanogaster muscle protein MSP-300. Genomics (2002) 1.95
Regulation of alternative polyadenylation by genomic imprinting. Genes Dev (2008) 1.89
Bax/Bak-dependent release of DDP/TIMM8a promotes Drp1-mediated mitochondrial fission and mitoptosis during programmed cell death. Curr Biol (2005) 1.87
An association between variants in the IGF2 gene and Beckwith-Wiedemann syndrome: interaction between genotype and epigenotype. Hum Mol Genet (2003) 1.85
Conserved methylation imprints in the human and mouse GRB10 genes with divergent allelic expression suggests differential reading of the same mark. Hum Mol Genet (2003) 1.80
Identification of the imprinted KLF14 transcription factor undergoing human-specific accelerated evolution. PLoS Genet (2007) 1.79
Bile duct proliferation in liver-specific Jag1 conditional knockout mice: effects of gene dosage. Hepatology (2007) 1.78
The importance of imprinting in the human placenta. PLoS Genet (2010) 1.74
The primate-specific microRNA gene cluster (C19MC) is imprinted in the placenta. Hum Mol Genet (2010) 1.73
Facial features in Alagille syndrome: specific or cholestasis facies? Am J Med Genet (2002) 1.73
Transposable elements re-wire and fine-tune the transcriptome. PLoS Genet (2013) 1.70
Genome-wide parent-of-origin DNA methylation analysis reveals the intricacies of human imprinting and suggests a germline methylation-independent mechanism of establishment. Genome Res (2014) 1.64
Germline melanocortin-1-receptor genotype is associated with severity of cutaneous phenotype in congenital melanocytic nevi: a role for MC1R in human fetal development. J Invest Dermatol (2012) 1.56
Common variants at the MHC locus and at chromosome 16q24.1 predispose to Barrett's esophagus. Nat Genet (2012) 1.52
G9a histone methyltransferase contributes to imprinting in the mouse placenta. Mol Cell Biol (2007) 1.51
WAMIDEX: a web atlas of murine genomic imprinting and differential expression. Epigenetics (2008) 1.46
Functional variants of the central bile acid sensor FXR identified in intrahepatic cholestasis of pregnancy. Gastroenterology (2007) 1.46
Supernumerary digital flexion creases: an additional clinical manifestation of Alagille syndrome. Am J Med Genet (2002) 1.42
The parental non-equivalence of imprinting control regions during mammalian development and evolution. PLoS Genet (2010) 1.41
MATERNALLY EXPRESSED PAB C-TERMINAL, a novel imprinted gene in Arabidopsis, encodes the conserved C-terminal domain of polyadenylate binding proteins. Plant Cell (2008) 1.39
Chromosome-wide identification of novel imprinted genes using microarrays and uniparental disomies. Nucleic Acids Res (2006) 1.37
Protection against de novo methylation is instrumental in maintaining parent-of-origin methylation inherited from the gametes. Mol Cell (2012) 1.36
A novel variant of Inpp5f is imprinted in brain, and its expression is correlated with differential methylation of an internal CpG island. Mol Cell Biol (2005) 1.32
Characterization of Notch receptor expression in the developing mammalian heart and liver. Am J Med Genet (2002) 1.32
Comparative analysis of human chromosome 7q21 and mouse proximal chromosome 6 reveals a placental-specific imprinted gene, TFPI2/Tfpi2, which requires EHMT2 and EED for allelic-silencing. Genome Res (2008) 1.28
Patterns of evolutionary conservation in the nesprin genes highlight probable functionally important protein domains and isoforms. Biochem Soc Trans (2008) 1.26
TBX22 missense mutations found in patients with X-linked cleft palate affect DNA binding, sumoylation, and transcriptional repression. Am J Hum Genet (2007) 1.23
Resources for methylome analysis suitable for gene knockout studies of potential epigenome modifiers. Gigascience (2012) 1.22
Independent and population-specific association of risk variants at the IRGM locus with Crohn's disease. Hum Mol Genet (2010) 1.21
Craniofacial expression of human and murine TBX22 correlates with the cleft palate and ankyloglossia phenotype observed in CPX patients. Hum Mol Genet (2002) 1.20
The role of imprinted genes in humans. Mol Aspects Med (2012) 1.19
A survey of tissue-specific genomic imprinting in mammals. Mol Genet Genomics (2012) 1.19
High-throughput analysis of candidate imprinted genes and allele-specific gene expression in the human term placenta. BMC Genet (2010) 1.18
Familial basaloid follicular hamartoma: lesional characterization and review of the literature. Am J Dermatopathol (2003) 1.14
Transcript- and tissue-specific imprinting of a tumour suppressor gene. Hum Mol Genet (2008) 1.13
Reciprocal imprinting of human GRB10 in placental trophoblast and brain: evolutionary conservation of reversed allelic expression. Hum Mol Genet (2009) 1.12
Methylation screening of reciprocal genome-wide UPDs identifies novel human-specific imprinted genes. Hum Mol Genet (2011) 1.09
Genome-wide allelic methylation analysis reveals disease-specific susceptibility to multiple methylation defects in imprinting syndromes. Hum Mutat (2013) 1.09
The emerging role of epigenetic mechanisms in the etiology of neural tube defects. Epigenetics (2011) 1.08
Exploring the spectrum of 3-M syndrome, a primordial short stature disorder of disrupted ubiquitination. Clin Endocrinol (Oxf) (2012) 1.08
Epigenetic allele silencing unveils recessive RYR1 mutations in core myopathies. Am J Hum Genet (2006) 1.07
Evaluation of allelic expression of imprinted genes in adult human blood. PLoS One (2010) 1.05
Epigenetic control of alternative mRNA processing at the imprinted Herc3/Nap1l5 locus. Nucleic Acids Res (2012) 1.04
Transcriptional profiles underlying parent-of-origin effects in seeds of Arabidopsis thaliana. BMC Plant Biol (2010) 1.03
Tbx22null mice have a submucous cleft palate due to reduced palatal bone formation and also display ankyloglossia and choanal atresia phenotypes. Hum Mol Genet (2009) 1.02
The effects of culture on genomic imprinting profiles in human embryonic and fetal mesenchymal stem cells. Epigenetics (2011) 0.98
Maternal inheritance of a promoter variant in the imprinted PHLDA2 gene significantly increases birth weight. Am J Hum Genet (2012) 0.98
The consequences of uniparental disomy and copy number neutral loss-of-heterozygosity during human development and cancer. Biol Cell (2011) 0.98
Intergenerational obesity involves both the father and the mother. Am J Clin Nutr (2008) 0.97
Chromosome 7p disruptions in Silver Russell syndrome: delineating an imprinted candidate gene region. Hum Genet (2002) 0.97
Allele-specific demethylation at an imprinted mammalian promoter. Nucleic Acids Res (2007) 0.96
Large-scale modelling of the divergent spectrin repeats in nesprins: giant modular proteins. PLoS One (2013) 0.95
The dystrotelin, dystrophin and dystrobrevin superfamily: new paralogues and old isoforms. BMC Genomics (2007) 0.95
Novel isoforms of the CARD8 (TUCAN) gene evade a nonsense mutation. Eur J Hum Genet (2008) 0.95
Retrotransposition and genomic imprinting. Brief Funct Genomics (2010) 0.95
Structural evolution of the BRCA1 genomic region in primates. Genomics (2004) 0.94
Genomic imprinting of Dopa decarboxylase in heart and reciprocal allelic expression with neighboring Grb10. Mol Cell Biol (2007) 0.94
The β-globin locus control region in combination with the EF1α short promoter allows enhanced lentiviral vector-mediated erythroid gene expression with conserved multilineage activity. Mol Ther (2012) 0.93
Stability of genomic imprinting and gestational-age dynamic methylation in complicated pregnancies conceived following assisted reproductive technologies. Biol Reprod (2013) 0.93
Functional characterization of two novel 5' untranslated exons reveals a complex regulation of NOD2 protein expression. BMC Genomics (2007) 0.93
Identification and characterization of an imprinted antisense RNA (MESTIT1) in the human MEST locus on chromosome 7q32. Hum Mol Genet (2002) 0.92
STOX1 is not imprinted and is not likely to be involved in preeclampsia. Nat Genet (2007) 0.90
Segmental paternal uniparental disomy (patUPD) of 14q32 with abnormal methylation elicits the characteristic features of complete patUPD14. Am J Med Genet A (2010) 0.90
Next generation sequencing in epigenetics: insights and challenges. Semin Cell Dev Biol (2011) 0.89
Interaction of the deafness-dystonia protein DDP/TIMM8a with the signal transduction adaptor molecule STAM1. Biochem Biophys Res Commun (2003) 0.89
Constitutional mosaic genome-wide uniparental disomy due to diploidisation: an unusual cancer-predisposing mechanism. J Med Genet (2010) 0.89
Loss of a single amino acid from dystrophin resulting in Duchenne muscular dystrophy with retention of dystrophin protein. Hum Mutat (2003) 0.89
Human imprinted retrogenes exhibit non-canonical imprint chromatin signatures and reside in non-imprinted host genes. Nucleic Acids Res (2011) 0.89
Genomic imprinting in fetal growth and development. Expert Rev Mol Med (2002) 0.88
Mutation, selection, and evolution of the Crohn disease susceptibility gene CARD15. Hum Mutat (2006) 0.88
Separation of the PROX1 gene from upstream conserved elements in a complex inversion/translocation patient with hypoplastic left heart. Eur J Hum Genet (2009) 0.88