Published in FEBS Lett on February 02, 2007
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Membrane translocation of t-SNARE protein syntaxin-4 abrogates ground-state pluripotency in mouse embryonic stem cells. Sci Rep (2017) 0.75
A human protein-protein interaction network: a resource for annotating the proteome. Cell (2005) 18.97
Snail, Zeb and bHLH factors in tumour progression: an alliance against the epithelial phenotype? Nat Rev Cancer (2007) 18.69
Met, metastasis, motility and more. Nat Rev Mol Cell Biol (2003) 14.30
Negative feedback loop of Wnt signaling through upregulation of conductin/axin2 in colorectal and liver tumors. Mol Cell Biol (2002) 8.60
Loss of acetylation at Lys16 and trimethylation at Lys20 of histone H4 is a common hallmark of human cancer. Nat Genet (2005) 8.45
Wnt signalling and its impact on development and cancer. Nat Rev Cancer (2008) 8.37
Epithelial-mesenchymal transition in breast cancer relates to the basal-like phenotype. Cancer Res (2008) 6.95
Interactions between cancer stem cells and their niche govern metastatic colonization. Nature (2011) 6.94
Canonical Wnt/beta-catenin signaling prevents osteoblasts from differentiating into chondrocytes. Dev Cell (2005) 6.90
Targeting MET in cancer: rationale and progress. Nat Rev Cancer (2012) 6.43
The transcription factor Slug represses E-cadherin expression and induces epithelial to mesenchymal transitions: a comparison with Snail and E47 repressors. J Cell Sci (2003) 6.24
DeltaEF1 is a transcriptional repressor of E-cadherin and regulates epithelial plasticity in breast cancer cells. Oncogene (2005) 5.74
Metastatic colonization requires the repression of the epithelial-mesenchymal transition inducer Prrx1. Cancer Cell (2012) 5.53
Hakai, a c-Cbl-like protein, ubiquitinates and induces endocytosis of the E-cadherin complex. Nat Cell Biol (2002) 5.02
Cutaneous cancer stem cell maintenance is dependent on beta-catenin signalling. Nature (2008) 4.60
Transforming growth factor beta-1 induces snail transcription factor in epithelial cell lines: mechanisms for epithelial mesenchymal transitions. J Biol Chem (2003) 4.55
Deciphering the function of canonical Wnt signals in development and disease: conditional loss- and gain-of-function mutations of beta-catenin in mice. Genes Dev (2008) 4.38
Correlation of Snail expression with histological grade and lymph node status in breast carcinomas. Oncogene (2002) 4.20
Snail mediates E-cadherin repression by the recruitment of the Sin3A/histone deacetylase 1 (HDAC1)/HDAC2 complex. Mol Cell Biol (2004) 4.15
Hematopoietic stem cell and multilineage defects generated by constitutive beta-catenin activation. Nat Immunol (2006) 3.98
Mutations in the desmosomal protein plakophilin-2 are common in arrhythmogenic right ventricular cardiomyopathy. Nat Genet (2004) 3.88
Balancing cell adhesion and Wnt signaling, the key role of beta-catenin. Curr Opin Genet Dev (2005) 3.79
Transcriptional regulation of cadherins during development and carcinogenesis. Int J Dev Biol (2004) 3.64
beta-Catenin is required for specification of proximal/distal cell fate during lung morphogenesis. J Biol Chem (2003) 3.37
Force measurements in E-cadherin-mediated cell doublets reveal rapid adhesion strengthened by actin cytoskeleton remodeling through Rac and Cdc42. J Cell Biol (2004) 3.06
Wnt/beta-catenin is essential for intestinal homeostasis and maintenance of intestinal stem cells. Mol Cell Biol (2007) 3.06
Interplay of cadherin-mediated cell adhesion and canonical Wnt signaling. Cold Spring Harb Perspect Biol (2010) 3.02
MACC1, a newly identified key regulator of HGF-MET signaling, predicts colon cancer metastasis. Nat Med (2008) 3.00
Essential role of BCL9-2 in the switch between beta-catenin's adhesive and transcriptional functions. Genes Dev (2004) 2.99
beta-Catenin signals regulate cell growth and the balance between progenitor cell expansion and differentiation in the nervous system. Dev Biol (2003) 2.85
SNAI1 is required for tumor growth and lymph node metastasis of human breast carcinoma MDA-MB-231 cells. Cancer Res (2007) 2.80
Expression of DeltaNLef1 in mouse epidermis results in differentiation of hair follicles into squamous epidermal cysts and formation of skin tumours. Development (2002) 2.79
Long-term, multilineage hematopoiesis occurs in the combined absence of beta-catenin and gamma-catenin. Blood (2007) 2.78
Wnt/beta-catenin signaling acts upstream of N-myc, BMP4, and FGF signaling to regulate proximal-distal patterning in the lung. Dev Biol (2005) 2.73
Genetic profiling of epithelial cells expressing E-cadherin repressors reveals a distinct role for Snail, Slug, and E47 factors in epithelial-mesenchymal transition. Cancer Res (2006) 2.73
A molecular role for lysyl oxidase-like 2 enzyme in snail regulation and tumor progression. EMBO J (2005) 2.71
The role of Axin2 in calvarial morphogenesis and craniosynostosis. Development (2005) 2.63
Epithelial-mesenchymal transitions: insights from development. Development (2012) 2.58
Beta1 integrin deletion from the basal compartment of the mammary epithelium affects stem cells. Nat Cell Biol (2008) 2.46
Pre-EMTing metastasis? Recapitulation of morphogenetic processes in cancer. Clin Exp Metastasis (2007) 2.41
Role of beta-catenin in synaptic vesicle localization and presynaptic assembly. Neuron (2003) 2.37
Helicobacter pylori CagA protein targets the c-Met receptor and enhances the motogenic response. J Cell Biol (2003) 2.37
Wnt signaling in stem and cancer stem cells. Curr Opin Cell Biol (2013) 2.35
Regional copy number-independent deregulation of transcription in cancer. Nat Genet (2006) 2.33
Neural crest-derived cells with stem cell features can be traced back to multiple lineages in the adult skin. J Cell Biol (2006) 2.32
Rap1 regulates the formation of E-cadherin-based cell-cell contacts. Mol Cell Biol (2004) 2.31
Host microenvironment in breast cancer development: epithelial-mesenchymal transition in breast cancer development. Breast Cancer Res (2003) 2.30
Continuous tooth generation in mouse is induced by activated epithelial Wnt/beta-catenin signaling. Proc Natl Acad Sci U S A (2006) 2.25
HMGA2 and Smads co-regulate SNAIL1 expression during induction of epithelial-to-mesenchymal transition. J Biol Chem (2008) 2.22
SOX2 is an oncogene activated by recurrent 3q26.3 amplifications in human lung squamous cell carcinomas. PLoS One (2010) 2.21
Reciprocal requirements for EDA/EDAR/NF-kappaB and Wnt/beta-catenin signaling pathways in hair follicle induction. Dev Cell (2009) 2.17
Johnson-Kendall-Roberts theory applied to living cells. Phys Rev Lett (2005) 2.13
Epithelial to mesenchymal transition and breast cancer. Breast Cancer Res (2009) 2.05
Essential role of the Wnt pathway effector Tcf-1 for the establishment of functional CD8 T cell memory. Proc Natl Acad Sci U S A (2010) 2.05
The transcription factors Slug and Snail act as repressors of Claudin-1 expression in epithelial cells. Biochem J (2006) 2.03
The ankyrin repeat protein Diversin recruits Casein kinase Iepsilon to the beta-catenin degradation complex and acts in both canonical Wnt and Wnt/JNK signaling. Genes Dev (2002) 2.02
Deletion of beta-catenin impairs T cell development. Nat Immunol (2003) 2.01
Role of FGF10/FGFR2b signaling during mammary gland development in the mouse embryo. Development (2002) 1.99
c-Met is essential for wound healing in the skin. J Cell Biol (2007) 1.98
E-cadherin is crucial for embryonic stem cell pluripotency and can replace OCT4 during somatic cell reprogramming. EMBO Rep (2011) 1.93
Requirement of plakophilin 2 for heart morphogenesis and cardiac junction formation. J Cell Biol (2004) 1.92
Fgf10 expression identifies parabronchial smooth muscle cell progenitors and is required for their entry into the smooth muscle cell lineage. Development (2005) 1.88
Pancreas-specific deletion of beta-catenin reveals Wnt-dependent and Wnt-independent functions during development. Curr Biol (2005) 1.87
Upregulation of MMP-9 in MDCK epithelial cell line in response to expression of the Snail transcription factor. J Cell Sci (2005) 1.87
Mouse embryonic mammogenesis as a model for the molecular regulation of pattern formation. Differentiation (2003) 1.85
Wnt signaling in stem and cancer stem cells. Semin Cell Dev Biol (2010) 1.79
How to make tubes: signaling by the Met receptor tyrosine kinase. Trends Cell Biol (2003) 1.77
Activating mutations of the tyrosine kinase receptor FGFR3 are associated with benign skin tumors in mice and humans. Hum Mol Genet (2005) 1.74
The metastasis-associated gene S100A4 is a novel target of beta-catenin/T-cell factor signaling in colon cancer. Gastroenterology (2006) 1.73
Beta-catenin regulates Cripto- and Wnt3-dependent gene expression programs in mouse axis and mesoderm formation. Development (2003) 1.73
The epithelial-mesenchymal transition under control: global programs to regulate epithelial plasticity. Semin Cancer Biol (2012) 1.65
Aberrant Wnt/beta-catenin signaling can induce chromosomal instability in colon cancer. Proc Natl Acad Sci U S A (2006) 1.64
Micro-RNA signature of the epithelial-mesenchymal transition in endometrial carcinosarcoma. J Pathol (2010) 1.63
Beta-catenin regulation during the cell cycle: implications in G2/M and apoptosis. Mol Biol Cell (2003) 1.62
The morphological and molecular features of the epithelial-to-mesenchymal transition. Nat Protoc (2009) 1.60
Distinct roles of Wnt/beta-catenin and Bmp signaling during early cardiogenesis. Proc Natl Acad Sci U S A (2007) 1.60
Isolation of mouse mammary epithelial progenitor cells with basal characteristics from the Comma-Dbeta cell line. Dev Biol (2006) 1.59
Targeted activation of beta-catenin signaling in basal mammary epithelial cells affects mammary development and leads to hyperplasia. Development (2004) 1.58
The tyrosine phosphatase Shp2 in development and cancer. Adv Cancer Res (2010) 1.58
The human tissue plasminogen activator-Cre mouse: a new tool for targeting specifically neural crest cells and their derivatives in vivo. Dev Biol (2003) 1.56
Selection of multipotent stem cells during morphogenesis of small intestinal crypts of Lieberkuhn is perturbed by stimulation of Lef-1/beta-catenin signaling. J Biol Chem (2002) 1.56
Genetic interaction between Wnt/beta-catenin and BMP receptor signaling during formation of the AER and the dorsal-ventral axis in the limb. Genes Dev (2003) 1.55