Published in Biophys J on February 16, 2007
An oxygen scavenging system for improvement of dye stability in single-molecule fluorescence experiments. Biophys J (2007) 4.49
Do-it-yourself guide: how to use the modern single-molecule toolkit. Nat Methods (2008) 2.52
RNA dynamics: it is about time. Curr Opin Struct Biol (2008) 2.31
Experimental determination of upper bound for transition path times in protein folding from single-molecule photon-by-photon trajectories. Proc Natl Acad Sci U S A (2009) 2.29
RNA folding: conformational statistics, folding kinetics, and ion electrostatics. Annu Rev Biophys (2008) 2.00
Design principles for riboswitch function. PLoS Comput Biol (2009) 1.44
Single-molecule observations of ribosome function. Curr Opin Struct Biol (2009) 1.38
Removal of covalent heterogeneity reveals simple folding behavior for P4-P6 RNA. J Biol Chem (2011) 0.95
Microsecond folding experiments and simulations: a match is made. Phys Chem Chem Phys (2013) 0.91
Single-Molecule Fluorescence Studies of RNA: A Decade's Progress. Chem Phys Lett (2009) 0.81
Understanding the kinetic mechanism of RNA single base pair formation. Proc Natl Acad Sci U S A (2015) 0.79
BOBA FRET: bootstrap-based analysis of single-molecule FRET data. PLoS One (2013) 0.78
Structure-function relationship of substituted bromomethylcoumarins in nucleoside specificity of RNA alkylation. PLoS One (2013) 0.78
Codon-dependent tRNA fluctuations monitored with fluorescence polarization. Biophys J (2010) 0.78
Kinetic and thermodynamic framework for P4-P6 RNA reveals tertiary motif modularity and modulation of the folding preferred pathway. Proc Natl Acad Sci U S A (2016) 0.76
Single-molecule Förster resonance energy transfer studies of RNA structure, dynamics and function. Biophys Rev (2009) 0.75
First passage, looping, and direct transition in expanding and narrowing tubes: Effects of the entropy potential. J Chem Phys (2017) 0.75
Self-splicing RNA: autoexcision and autocyclization of the ribosomal RNA intervening sequence of Tetrahymena. Cell (1982) 12.12
A single-molecule study of RNA catalysis and folding. Science (2000) 7.06
Site-specific modification of pre-mRNA: the 2'-hydroxyl groups at the splice sites. Science (1992) 5.87
Kinetics of conformational fluctuations in DNA hairpin-loops. Proc Natl Acad Sci U S A (1998) 5.34
Initiation and re-initiation of DNA unwinding by the Escherichia coli Rep helicase. Nature (2002) 5.13
Dynamics of fluorescence fluctuations in green fluorescent protein observed by fluorescence correlation spectroscopy. Proc Natl Acad Sci U S A (1998) 4.72
Measuring conformational dynamics of biomolecules by single molecule fluorescence spectroscopy. Nat Struct Biol (2000) 4.34
New loop-loop tertiary interactions in self-splicing introns of subgroup IC and ID: a complete 3D model of the Tetrahymena thermophila ribozyme. Chem Biol (1996) 2.81
Biotechnology at low Reynolds numbers. Biophys J (1996) 2.72
A specific monovalent metal ion integral to the AA platform of the RNA tetraloop receptor. Nat Struct Biol (1998) 2.71
A four-way junction accelerates hairpin ribozyme folding via a discrete intermediate. Proc Natl Acad Sci U S A (2003) 2.65
Mg2+-dependent conformational change of RNA studied by fluorescence correlation and FRET on immobilized single molecules. Proc Natl Acad Sci U S A (2002) 2.47
Small angle X-ray scattering reveals a compact intermediate in RNA folding. Nat Struct Biol (2000) 2.27
Single-molecule fluorescence resonance energy transfer reveals a dynamic equilibrium between closed and open conformations of syntaxin 1. Proc Natl Acad Sci U S A (2003) 2.18
Assembly of core helices and rapid tertiary folding of a small bacterial group I ribozyme. Proc Natl Acad Sci U S A (2003) 1.75
Folding mechanism of the Tetrahymena ribozyme P4-P6 domain. Biochemistry (2000) 1.56
Multiple folding pathways for the P4-P6 RNA domain. Biochemistry (2000) 1.51
A three-state mechanism for DNA hairpin folding characterized by multiparameter fluorescence fluctuation spectroscopy. J Am Chem Soc (2006) 1.38
Femtomole mixer for microsecond kinetic studies of protein folding. Anal Chem (2004) 1.35
Secondary structure and secondary structure dynamics of DNA hairpins complexed with HIV-1 NC protein. Biophys J (2004) 1.26
DNA cleavage catalysed by the ribozyme from Tetrahymena. Nature (1990) 1.24
The P4-P6 domain directs higher order folding of the Tetrahymena ribozyme core. Biochemistry (1997) 1.12
RNA tertiary folding monitored by fluorescence of covalently attached pyrene. Biochemistry (1999) 1.07
Conformational changes of the H+-ATPase from Escherichia coli upon nucleotide binding detected by single molecule fluorescence. FEBS Lett (1998) 1.03
Single molecule detection of DNA looping by NgoMIV restriction endonuclease. Biophys J (2003) 0.92
SLC24A5, a putative cation exchanger, affects pigmentation in zebrafish and humans. Science (2005) 12.02
Direct detection of DNA methylation during single-molecule, real-time sequencing. Nat Methods (2010) 9.75
Precision and functional specificity in mRNA decay. Proc Natl Acad Sci U S A (2002) 8.20
Genome-wide analysis of mRNA translation profiles in Saccharomyces cerevisiae. Proc Natl Acad Sci U S A (2003) 7.45
Extensive association of functionally and cytotopically related mRNAs with Puf family RNA-binding proteins in yeast. PLoS Biol (2004) 6.38
Acetylation of metabolic enzymes coordinates carbon source utilization and metabolic flux. Science (2010) 6.04
Clinical findings in 111 cases of influenza A (H7N9) virus infection. N Engl J Med (2013) 5.38
tRNA dynamics on the ribosome during translation. Proc Natl Acad Sci U S A (2004) 5.38
Correlating structural dynamics and function in single ribozyme molecules. Science (2002) 5.16
Initiation and re-initiation of DNA unwinding by the Escherichia coli Rep helicase. Nature (2002) 5.13
Complications of colonoscopy in an integrated health care delivery system. Ann Intern Med (2006) 5.10
Integrated molecular genetic profiling of pediatric high-grade gliomas reveals key differences with the adult disease. J Clin Oncol (2010) 4.94
Large-scale association analyses identify new loci influencing glycemic traits and provide insight into the underlying biological pathways. Nat Genet (2012) 4.73
GWAS of 126,559 individuals identifies genetic variants associated with educational attainment. Science (2013) 4.71
Proton pump inhibitor and histamine 2 receptor antagonist use and vitamin B12 deficiency. JAMA (2013) 4.67
tRNA selection and kinetic proofreading in translation. Nat Struct Mol Biol (2004) 4.54
Impact of endoscopic surveillance on mortality from Barrett's esophagus-associated esophageal adenocarcinomas. Gastroenterology (2013) 4.43
Diverse RNA-binding proteins interact with functionally related sets of RNAs, suggesting an extensive regulatory system. PLoS Biol (2008) 4.34
Concordant regulation of translation and mRNA abundance for hundreds of targets of a human microRNA. PLoS Biol (2009) 4.32
Probable limited person-to-person transmission of highly pathogenic avian influenza A (H5N1) virus in China. Lancet (2008) 4.17
Validation of ITD mutations in FLT3 as a therapeutic target in human acute myeloid leukaemia. Nature (2012) 4.01
SAFA: semi-automated footprinting analysis software for high-throughput quantification of nucleic acid footprinting experiments. RNA (2005) 3.95
Abdominal obesity and body mass index as risk factors for Barrett's esophagus. Gastroenterology (2007) 3.94
Gramene: a resource for comparative grass genomics. Nucleic Acids Res (2002) 3.72
Nanomechanical measurements of the sequence-dependent folding landscapes of single nucleic acid hairpins. Proc Natl Acad Sci U S A (2006) 3.56
Direct measurement of the full, sequence-dependent folding landscape of a nucleic acid. Science (2006) 3.49
Gramene: a bird's eye view of cereal genomes. Nucleic Acids Res (2006) 3.47
Neuronal SIRT1 activation as a novel mechanism underlying the prevention of Alzheimer disease amyloid neuropathology by calorie restriction. J Biol Chem (2006) 3.40
Systematic identification of mRNAs recruited to argonaute 2 by specific microRNAs and corresponding changes in transcript abundance. PLoS One (2008) 3.38
Exploring the temperature-stress metabolome of Arabidopsis. Plant Physiol (2004) 3.30
Genome-wide identification of mRNAs associated with the translational regulator PUMILIO in Drosophila melanogaster. Proc Natl Acad Sci U S A (2006) 3.27
Genome sequencing reveals insights into physiology and longevity of the naked mole rat. Nature (2011) 3.19
Gramene, a tool for grass genomics. Plant Physiol (2002) 3.14
Accessory proteins stabilize the acceptor complex for synaptobrevin, the 1:1 syntaxin/SNAP-25 complex. Structure (2008) 3.01
Phosphatase SHP-1 promotes TLR- and RIG-I-activated production of type I interferon by inhibiting the kinase IRAK1. Nat Immunol (2008) 2.89
Exploring the folding landscape of a structured RNA. Proc Natl Acad Sci U S A (2001) 2.78
A prospective and open-label study for the efficacy and safety of telbivudine in pregnancy for the prevention of perinatal transmission of hepatitis B virus infection. J Hepatol (2011) 2.75
Single molecule observation of liposome-bilayer fusion thermally induced by soluble N-ethyl maleimide sensitive-factor attachment protein receptors (SNAREs). Biophys J (2004) 2.75
One at a time, live tracking of NGF axonal transport using quantum dots. Proc Natl Acad Sci U S A (2007) 2.74
Coarse-grained modeling of large RNA molecules with knowledge-based potentials and structural filters. RNA (2009) 2.63
Dissecting eukaryotic translation and its control by ribosome density mapping. Nucleic Acids Res (2005) 2.52
Mg2+-dependent conformational change of RNA studied by fluorescence correlation and FRET on immobilized single molecules. Proc Natl Acad Sci U S A (2002) 2.47
Testing electrostatic complementarity in enzyme catalysis: hydrogen bonding in the ketosteroid isomerase oxyanion hole. PLoS Biol (2006) 2.41
Molecular architecture and assembly principles of Vibrio cholerae biofilms. Science (2012) 2.36
Comparative analysis of bat genomes provides insight into the evolution of flight and immunity. Science (2012) 2.29
Abdominal obesity, ethnicity and gastro-oesophageal reflux symptoms. Gut (2006) 2.28
In vitro system capable of differentiating fast Ca2+-triggered content mixing from lipid exchange for mechanistic studies of neurotransmitter release. Proc Natl Acad Sci U S A (2011) 2.27
Rapid compaction during RNA folding. Proc Natl Acad Sci U S A (2002) 2.27
BRAF and KRAS mutations in colorectal hyperplastic polyps and serrated adenomas. Cancer Res (2003) 2.27
Quantitative and comprehensive decomposition of the ion atmosphere around nucleic acids. J Am Chem Soc (2007) 2.20
Structural transitions and thermodynamics of a glycine-dependent riboswitch from Vibrio cholerae. J Mol Biol (2006) 2.19
Gramene: development and integration of trait and gene ontologies for rice. Comp Funct Genomics (2002) 2.16
Exome sequencing of extreme phenotypes identifies DCTN4 as a modifier of chronic Pseudomonas aeruginosa infection in cystic fibrosis. Nat Genet (2012) 2.14
Single-molecule FRET-derived model of the synaptotagmin 1-SNARE fusion complex. Nat Struct Mol Biol (2010) 2.10
Meta-analysis of effectiveness of first-generation drug-eluting stents versus coronary artery bypass grafting for unprotected left main coronary disease. Am J Cardiol (2012) 2.07
Mutations of PIK3CA in gastric adenocarcinoma. BMC Cancer (2005) 2.06
Synaptic proteins promote calcium-triggered fast transition from point contact to full fusion. Elife (2012) 2.04
Definition of disease-risk stratification groups in childhood medulloblastoma using combined clinical, pathologic, and molecular variables. J Clin Oncol (2010) 2.04
How fast is protein hydrophobic collapse? Proc Natl Acad Sci U S A (2003) 2.01
Comparative oncogenomics identifies breast tumors enriched in functional tumor-initiating cells. Proc Natl Acad Sci U S A (2011) 2.01
Challenges in enzyme mechanism and energetics. Annu Rev Biochem (2003) 2.00
Subnanometre single-molecule localization, registration and distance measurements. Nature (2010) 1.98
Site-specific labeling of the ribosome for single-molecule spectroscopy. Nucleic Acids Res (2005) 1.97
Orally bioavailable small-molecule inhibitor of transcription factor Stat3 regresses human breast and lung cancer xenografts. Proc Natl Acad Sci U S A (2012) 1.94
Biological phosphoryl-transfer reactions: understanding mechanism and catalysis. Annu Rev Biochem (2011) 1.94
Single-molecule studies of SNARE complex assembly reveal parallel and antiparallel configurations. Proc Natl Acad Sci U S A (2003) 1.94
Principles of RNA compaction: insights from the equilibrium folding pathway of the P4-P6 RNA domain in monovalent cations. J Mol Biol (2004) 1.90
Characterizing the initial encounter complex in cadherin adhesion. Structure (2009) 1.90
Abdominal obesity and the risk of esophageal and gastric cardia carcinomas. Cancer Epidemiol Biomarkers Prev (2008) 1.89
Human FcγRIIA induces anaphylactic and allergic reactions. Blood (2011) 1.86
Telbivudine prevents vertical transmission from HBeAg-positive women with chronic hepatitis B. Clin Gastroenterol Hepatol (2012) 1.84
Fluctuations of transfer RNAs between classical and hybrid states. Biophys J (2007) 1.82
A meta-analysis identifies new loci associated with body mass index in individuals of African ancestry. Nat Genet (2013) 1.82
Computational aeroacoustics of phonation, part II: Effects of flow parameters and ventricular folds. J Acoust Soc Am (2002) 1.82
Resolving cadherin interactions and binding cooperativity at the single-molecule level. Proc Natl Acad Sci U S A (2008) 1.81
Regulation of insulin-like growth factor-mammalian target of rapamycin signaling by microRNA in childhood adrenocortical tumors. Cancer Res (2010) 1.80
The fastest global events in RNA folding: electrostatic relaxation and tertiary collapse of the Tetrahymena ribozyme. J Mol Biol (2003) 1.80
Microbial biodegradation of polyaromatic hydrocarbons. FEMS Microbiol Rev (2008) 1.80
SHP-2 phosphatase negatively regulates the TRIF adaptor protein-dependent type I interferon and proinflammatory cytokine production. Immunity (2006) 1.79
Grape-derived polyphenolics prevent Abeta oligomerization and attenuate cognitive deterioration in a mouse model of Alzheimer's disease. J Neurosci (2008) 1.75
Valsartan lowers brain beta-amyloid protein levels and improves spatial learning in a mouse model of Alzheimer disease. J Clin Invest (2007) 1.74
Colonization of the Tibetan Plateau by the homoploid hybrid pine Pinus densata. Mol Ecol (2011) 1.74
Berberine lowers blood glucose in type 2 diabetes mellitus patients through increasing insulin receptor expression. Metabolism (2009) 1.73
The role of fluctuations in tRNA selection by the ribosome. Proc Natl Acad Sci U S A (2007) 1.69
Multiple native states reveal persistent ruggedness of an RNA folding landscape. Nature (2010) 1.69
A novel glucose ENFET based on the special reactivity of MnO2 nanoparticles. Biosens Bioelectron (2004) 1.68
DNA methylation increases nucleosome compaction and rigidity. J Am Chem Soc (2010) 1.67
Exploration of the transition state for tertiary structure formation between an RNA helix and a large structured RNA. J Mol Biol (2003) 1.67
MicroRNA-137, an HMGA1 target, suppresses colorectal cancer cell invasion and metastasis in mice by directly targeting FMNL2. Gastroenterology (2012) 1.64
Molecular mechanism of the synaptotagmin-SNARE interaction in Ca2+-triggered vesicle fusion. Nat Struct Mol Biol (2010) 1.64
Three-dimensional linear system analysis for breast tomosynthesis. Med Phys (2008) 1.63
Alkaline phosphatase revisited: hydrolysis of alkyl phosphates. Biochemistry (2002) 1.61
A multipath routing protocol based on clustering and ant colony optimization for wireless sensor networks. Sensors (Basel) (2010) 1.61
The paradoxical behavior of a highly structured misfolded intermediate in RNA folding. J Mol Biol (2006) 1.61