Published in Cancer Res on February 15, 2007
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MicroRNAs, diet, and cancer: new mechanistic insights on the epigenetic actions of phytochemicals. Mol Carcinog (2011) 1.04
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Control of microRNA biogenesis by TGFbeta signaling pathway-A novel role of Smads in the nucleus. Cytokine Growth Factor Rev (2009) 1.02
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Persistent DNA damage caused by low levels of mitomycin C induces irreversible cell senescence. Cell Cycle (2012) 1.01
Differential processing of let-7a precursors influences RRM2 expression and chemosensitivity in pancreatic cancer: role of LIN-28 and SET oncoprotein. PLoS One (2013) 1.00
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The micro-RNA 199b-5p regulatory circuit involves Hes1, CD15, and epigenetic modifications in medulloblastoma. Neuro Oncol (2012) 0.94
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Epstein-Barr virus EBNA1 protein regulates viral latency through effects on let-7 microRNA and dicer. J Virol (2014) 0.83
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Regulation of IGF -1 signaling by microRNAs. Front Genet (2015) 0.81
The effects of microRNA on the absorption, distribution, metabolism and excretion of drugs. Br J Pharmacol (2014) 0.81
Novel insights into miRNA in lung and heart inflammatory diseases. Mediators Inflamm (2014) 0.81
Downregulation of microRNA-409-3p promotes aggressiveness and metastasis in colorectal cancer: an indication for personalized medicine. J Transl Med (2015) 0.80
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Ultraviolet radiation-induced tumor necrosis factor alpha, which is linked to the development of cutaneous SCC, modulates differential epidermal microRNAs expression. Oncotarget (2016) 0.78
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miRNAs and Melanoma: How Are They Connected? Dermatol Res Pract (2011) 0.77
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Gadd45a promotes epigenetic gene activation by repair-mediated DNA demethylation. Nature (2007) 5.54
The novel histologic International Association for the Study of Lung Cancer/American Thoracic Society/European Respiratory Society classification system of lung adenocarcinoma is a stage-independent predictor of survival. J Clin Oncol (2012) 4.30
Combined deficiency of Tet1 and Tet2 causes epigenetic abnormalities but is compatible with postnatal development. Dev Cell (2013) 3.31
Integrative genomic analyses reveal an androgen-driven somatic alteration landscape in early-onset prostate cancer. Cancer Cell (2013) 3.08
Circulating miRNAs are correlated with tumor progression in prostate cancer. Int J Cancer (2011) 3.02
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RNA methylation by Dnmt2 protects transfer RNAs against stress-induced cleavage. Genes Dev (2010) 2.90
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Identification of a common gene expression signature in dilated cardiomyopathy across independent microarray studies. J Am Coll Cardiol (2006) 2.73
Epigenetic reactivation of tumor suppressor genes by a novel small-molecule inhibitor of human DNA methyltransferases. Cancer Res (2005) 2.57
LUMA (LUminometric Methylation Assay)--a high throughput method to the analysis of genomic DNA methylation. Exp Cell Res (2006) 2.48
RNA cytosine methylation analysis by bisulfite sequencing. Nucleic Acids Res (2008) 2.42
Marked gene transcript level alterations occur early during radical prostatectomy. Eur Urol (2007) 2.41
Equivalence test in quantitative reverse transcription polymerase chain reaction: confirmation of reference genes suitable for normalization. Anal Biochem (2004) 2.28
Targeted high throughput sequencing in clinical cancer settings: formaldehyde fixed-paraffin embedded (FFPE) tumor tissues, input amount and tumor heterogeneity. BMC Med Genomics (2011) 2.24
Yes and PI3K bind CD95 to signal invasion of glioblastoma. Cancer Cell (2008) 2.21
Functional diversity of DNA methyltransferase inhibitors in human cancer cell lines. Cancer Res (2006) 2.07
Aging and chronic sun exposure cause distinct epigenetic changes in human skin. PLoS Genet (2010) 2.03
An immune response enriched 72-gene prognostic profile for early-stage non-small-cell lung cancer. Clin Cancer Res (2009) 2.03
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Genome-wide promoter DNA methylation dynamics of human hematopoietic progenitor cells during differentiation and aging. Blood (2011) 1.92
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Epigenetically deregulated microRNA-375 is involved in a positive feedback loop with estrogen receptor alpha in breast cancer cells. Cancer Res (2010) 1.82
RNA cytosine methylation by Dnmt2 and NSun2 promotes tRNA stability and protein synthesis. Nat Struct Mol Biol (2012) 1.75
Methylation of human microRNA genes in normal and neoplastic cells. Cell Cycle (2007) 1.71
Global gene expression analysis reveals specific patterns of cell junctions in non-small cell lung cancer subtypes. Lung Cancer (2008) 1.71
Silencing of retrotransposons in Dictyostelium by DNA methylation and RNAi. Nucleic Acids Res (2005) 1.63
A Dnmt2-like protein mediates DNA methylation in Drosophila. Development (2003) 1.61
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Molecular cancer phenotype in normal prostate tissue. Eur Urol (2008) 1.58
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Identification of aberrant chromosomal regions from gene expression microarray studies applied to human breast cancer. Bioinformatics (2007) 1.50
Estimating large-scale signaling networks through nested effect models with intervention effects from microarray data. Bioinformatics (2008) 1.46
Dnmt2-dependent methylomes lack defined DNA methylation patterns. Proc Natl Acad Sci U S A (2013) 1.43
Azacytidine causes complex DNA methylation responses in myeloid leukemia. Mol Cancer Ther (2008) 1.43
Effects of infiltrating lymphocytes and estrogen receptor on gene expression and prognosis in breast cancer. Breast Cancer Res Treat (2008) 1.42
ERBB2 and TOP2A in breast cancer: a comprehensive analysis of gene amplification, RNA levels, and protein expression and their influence on prognosis and prediction. Clin Cancer Res (2010) 1.41
Characterization of DNA demethylation effects induced by 5-Aza-2'-deoxycytidine in patients with myelodysplastic syndrome. Cancer Res (2005) 1.38
DNA methyltransferase inhibitors for cancer therapy. Cancer J (2007) 1.37
Loss of EpCAM expression in breast cancer derived serum exosomes: role of proteolytic cleavage. Gynecol Oncol (2011) 1.37
TMPRSS2-ERG -specific transcriptional modulation is associated with prostate cancer biomarkers and TGF-β signaling. BMC Cancer (2011) 1.26
Systematic analysis of T7 RNA polymerase based in vitro linear RNA amplification for use in microarray experiments. BMC Genomics (2004) 1.25
RNA-mediated epigenetic heredity requires the cytosine methyltransferase Dnmt2. PLoS Genet (2013) 1.25
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Azacytidine inhibits RNA methylation at DNMT2 target sites in human cancer cell lines. Cancer Res (2009) 1.24
Coordinated expression of stathmin family members by far upstream sequence element-binding protein-1 increases motility in non-small cell lung cancer. Cancer Res (2009) 1.23
The maternal embryonic leucine zipper kinase (MELK) is upregulated in high-grade prostate cancer. J Mol Med (Berl) (2012) 1.23
Genome-wide DNA methylation events in TMPRSS2-ERG fusion-negative prostate cancers implicate an EZH2-dependent mechanism with miR-26a hypermethylation. Cancer Discov (2012) 1.21
Combinatorial RNAi for quantitative protein network analysis. Proc Natl Acad Sci U S A (2007) 1.21
Hydroxylation of 5-methylcytosine by TET2 maintains the active state of the mammalian HOXA cluster. Nat Commun (2012) 1.21
Natural products as DNA methyltransferase inhibitors: a computer-aided discovery approach. Mol Divers (2010) 1.20
Effect of morphology on ultrafast free carrier generation in polythiophene:fullerene organic solar cells. J Am Chem Soc (2010) 1.19
Prognostic role of E2F1 and members of the CDKN2A network in gastrointestinal stromal tumors. Clin Cancer Res (2005) 1.19
Capillary electrophoretic analysis of genomic DNA methylation levels. Nucleic Acids Res (2003) 1.19
Azacytidine and decitabine induce gene-specific and non-random DNA demethylation in human cancer cell lines. PLoS One (2011) 1.19
Role of miR-34a as a suppressor of L1CAM in endometrial carcinoma. Oncotarget (2014) 1.18
DNA methylation with a sting: an active DNA methylation system in the honeybee. Bioessays (2007) 1.17
Nucleoside drugs induce cellular differentiation by caspase-dependent degradation of stem cell factors. PLoS One (2010) 1.17
Large-scale comparative analyses of immunomarkers for diagnostic subtyping of non-small-cell lung cancer biopsies. Histopathology (2012) 1.16
EZH2 depletion blocks the proliferation of colon cancer cells. PLoS One (2011) 1.15
Integration of pathway knowledge into a reweighted recursive feature elimination approach for risk stratification of cancer patients. Bioinformatics (2010) 1.15
Gene expression in kidney cancer is associated with cytogenetic abnormalities, metastasis formation, and patient survival. Clin Cancer Res (2005) 1.13
Use of DNAzymes for site-specific analysis of ribonucleotide modifications. RNA (2007) 1.12
Ultrafast exciton dissociation followed by nongeminate charge recombination in PCDTBT:PCBM photovoltaic blends. J Am Chem Soc (2011) 1.11
Efficient RNA virus control in Drosophila requires the RNA methyltransferase Dnmt2. EMBO Rep (2013) 1.11
The anterior gradient 2 (AGR2) gene is overexpressed in prostate cancer and may be useful as a urine sediment marker for prostate cancer detection. Prostate (2010) 1.10
Systematic identification and molecular characterization of genes differentially expressed in breast and ovarian cancer. J Pathol (2005) 1.10
A simple strand-specific RNA-Seq library preparation protocol combining the Illumina TruSeq RNA and the dUTP methods. Biochem Biophys Res Commun (2012) 1.10
Epigenetic cancer therapy: Proof of concept and remaining challenges. Bioessays (2010) 1.09
The mouse cytosine-5 RNA methyltransferase NSun2 is a component of the chromatoid body and required for testis differentiation. Mol Cell Biol (2013) 1.08
From ORFeome to biology: a functional genomics pipeline. Genome Res (2004) 1.08
The effect of solvent additives on morphology and excited-state dynamics in PCPDTBT:PCBM photovoltaic blends. J Am Chem Soc (2012) 1.08
Reactivation of epigenetically silenced genes by DNA methyltransferase inhibitors: basic concepts and clinical applications. Epigenetics (2005) 1.08
Identification and meta-analysis of a small gene expression signature for the diagnosis of estrogen receptor status in invasive ductal breast cancer. Int J Cancer (2006) 1.06
Extensive methylation of promoter sequences silences lentiviral transgene expression during stem cell differentiation in vivo. Mol Ther (2012) 1.05
Knockout targeting of the Drosophila nap1 gene and examination of DNA repair tracts in the recombination products. Genetics (2003) 1.05
Lack of evidence for DNA methylation of Invader4 retroelements in Drosophila and implications for Dnmt2-mediated epigenetic regulation. Nat Genet (2010) 1.03
Differential expression of apoptotic genes PDIA3 and MAP3K5 distinguishes between low- and high-risk prostate cancer. Mol Cancer (2009) 1.02
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Serum miR-142-3p is associated with early relapse in operable lung adenocarcinoma patients. Lung Cancer (2013) 1.00