Published in Differentiation on July 02, 2007
Regulation of miR-200 family microRNAs and ZEB transcription factors in ovarian cancer: evidence supporting a mesothelial-to-epithelial transition. Gynecol Oncol (2009) 1.84
Phenotypic plasticity of neoplastic ovarian epithelium: unique cadherin profiles in tumor progression. Clin Exp Metastasis (2008) 1.65
Fibroblast growth factor 2 induces E-cadherin down-regulation via PI3K/Akt/mTOR and MAPK/ERK signaling in ovarian cancer cells. PLoS One (2013) 1.07
Primary peritoneal serous carcinoma: a clinicopathological and immunohistochemical study of six cases. Int J Clin Exp Pathol (2012) 0.99
Integrin beta3 down-regulates invasive features of ovarian cancer cells in SKOV3 cell subclones. J Cancer Res Clin Oncol (2008) 0.94
The cadherin switch in ovarian high-grade serous carcinoma is associated with disease progression. Virchows Arch (2011) 0.93
Downregulation of cell surface CA125/MUC16 induces epithelial-to-mesenchymal transition and restores EGFR signalling in NIH:OVCAR3 ovarian carcinoma cells. Br J Cancer (2011) 0.89
Regulation of cell-cell contact molecules and the metastatic phenotype of medullary thyroid carcinoma by the Raf-1/MEK/ERK pathway. Surgery (2008) 0.84
Hedgehog signaling pathway and ovarian cancer. Chin J Cancer Res (2013) 0.83
MUC16 mucin (CA125) regulates the formation of multicellular aggregates by altering β-catenin signaling. Am J Cancer Res (2014) 0.82
Up-regulated FASN expression promotes transcoelomic metastasis of ovarian cancer cell through epithelial-mesenchymal transition. Int J Mol Sci (2014) 0.82
Dual Roles of METCAM in the Progression of Different Cancers. J Oncol (2012) 0.79
Inhibition of STAT3 signaling as critical molecular event in resveratrol-suppressed ovarian cancer cells. J Ovarian Res (2015) 0.78
Reduced expression of FILIP1L, a novel WNT pathway inhibitor, is associated with poor survival, progression and chemoresistance in ovarian cancer. Oncotarget (2016) 0.75
SUSD2 expression in high-grade serous ovarian cancer correlates with increased patient survival and defective mesothelial clearance. Oncogenesis (2016) 0.75
A Novel Role of E-Cadherin-Based Adherens Junctions in Neoplastic Cell Dissemination. PLoS One (2015) 0.75
Changes in organelle position and epithelial architecture associated with loss of CrebA. Biol Open (2015) 0.75
Genomic and epigenomic landscapes of adult de novo acute myeloid leukemia. N Engl J Med (2013) 19.87
Expression of the ETV6-NTRK3 gene fusion as a primary event in human secretory breast carcinoma. Cancer Cell (2002) 5.58
The RAB25 small GTPase determines aggressiveness of ovarian and breast cancers. Nat Med (2004) 4.69
Identification of miR-145 and miR-146a as mediators of the 5q- syndrome phenotype. Nat Med (2009) 4.03
Recent insights into the role of Notch signaling in tumorigenesis. Blood (2005) 3.37
Jagged1-mediated Notch activation induces epithelial-to-mesenchymal transition through Slug-induced repression of E-cadherin. J Exp Med (2007) 3.05
A genetically defined model for human ovarian cancer. Cancer Res (2004) 3.02
Lipopolysaccharide signaling in endothelial cells. Lab Invest (2006) 2.58
Concurrent CIC mutations, IDH mutations, and 1p/19q loss distinguish oligodendrogliomas from other cancers. J Pathol (2011) 2.27
Recurrent somatic DICER1 mutations in nonepithelial ovarian cancers. N Engl J Med (2011) 2.25
Slug is a direct Notch target required for initiation of cardiac cushion cellularization. J Cell Biol (2008) 2.21
Notch activation results in phenotypic and functional changes consistent with endothelial-to-mesenchymal transformation. Circ Res (2004) 2.10
Smooth Muscle alpha-actin is a direct target of Notch/CSL. Circ Res (2006) 1.90
Overexpression of the anti-adhesin podocalyxin is an independent predictor of breast cancer progression. Cancer Res (2004) 1.90
Notch signaling in cardiac development. Circ Res (2008) 1.69
Notch activation induces endothelial cell cycle arrest and participates in contact inhibition: role of p21Cip1 repression. Mol Cell Biol (2004) 1.61
Molecular pathways regulating EGF-induced epithelio-mesenchymal transition in human ovarian surface epithelium. Am J Physiol Cell Physiol (2006) 1.59
Canadian anaplastic lymphoma kinase study: a model for multicenter standardization and optimization of ALK testing in lung cancer. J Thorac Oncol (2014) 1.55
Activated Notch4 inhibits angiogenesis: role of beta 1-integrin activation. Mol Cell Biol (2002) 1.52
Induction of papillary carcinoma in human ovarian surface epithelial cells using combined genetic elements and peritoneal microenvironment. Cell Cycle (2010) 1.48
Comprehensive analysis of mammalian miRNA* species and their role in myeloid cells. Blood (2011) 1.44
TRAF6 is an amplified oncogene bridging the RAS and NF-κB pathways in human lung cancer. J Clin Invest (2011) 1.42
Identification of sokotrasterol sulfate as a novel proangiogenic steroid. Circ Res (2006) 1.41
Cyclooxygenase-2 functions as a downstream mediator of lysophosphatidic acid to promote aggressive behavior in ovarian carcinoma cells. Cancer Res (2005) 1.39
Genome-wide identification of human microRNAs located in leukemia-associated genomic alterations. Blood (2010) 1.36
Regulation of BRCA1 expression and its relationship to sporadic breast cancer. Breast Cancer Res (2002) 1.35
Minimal contribution of marrow-derived endothelial precursors to tumor vasculature. J Immunol (2005) 1.31
Notch4 inhibits endothelial apoptosis via RBP-Jkappa-dependent and -independent pathways. J Biol Chem (2003) 1.29
Collagen-IV and laminin-1 regulate estrogen receptor alpha expression and function in mouse mammary epithelial cells. J Cell Sci (2003) 1.27
The origin of ovarian carcinomas: a developmental view. Gynecol Oncol (2008) 1.26
MicroRNA-146a disrupts hematopoietic differentiation and survival. Exp Hematol (2010) 1.25
The CD34-related molecule podocalyxin is a potent inducer of microvillus formation. PLoS One (2007) 1.25
Overexpression of follicle-stimulating hormone receptor activates oncogenic pathways in preneoplastic ovarian surface epithelial cells. J Clin Endocrinol Metab (2004) 1.25
Notch initiates the endothelial-to-mesenchymal transition in the atrioventricular canal through autocrine activation of soluble guanylyl cyclase. Dev Cell (2011) 1.22
Roles of reactive oxygen species in angiopoietin-1/tie-2 receptor signaling. FASEB J (2005) 1.21
Cell motility and spreading are suppressed by HOXA4 in ovarian cancer cells: possible involvement of beta1 integrin. Mol Cancer Res (2009) 1.17
The anti-adhesive mucin podocalyxin may help initiate the transperitoneal metastasis of high grade serous ovarian carcinoma. Clin Exp Metastasis (2012) 1.13
Angiopoietin-1 activates both anti- and proapoptotic mitogen-activated protein kinases. FASEB J (2003) 1.12
Pigment epithelium-derived factor is estrogen sensitive and inhibits the growth of human ovarian cancer and ovarian surface epithelial cells. Endocrinology (2006) 1.12
Expression and function of HOXA genes in normal and neoplastic ovarian epithelial cells. Differentiation (2008) 1.10
Multiple roles of the candidate oncogene ZNF217 in ovarian epithelial neoplastic progression. Int J Cancer (2007) 1.10
Gonadotropins activate proteolysis and increase invasion through protein kinase A and phosphatidylinositol 3-kinase pathways in human epithelial ovarian cancer cells. Cancer Res (2006) 1.10
Mechanisms underlying p53 regulation of PIK3CA transcription in ovarian surface epithelium and in ovarian cancer. J Cell Sci (2008) 1.09
Differential regulation of transforming growth factor beta signaling pathways by Notch in human endothelial cells. J Biol Chem (2009) 1.07
The specificity of the FOXL2 c.402C>G somatic mutation: a survey of solid tumors. PLoS One (2009) 1.07
Involvement of endothelial progenitor cells in tumor vascularization. Microvasc Res (2010) 1.06
Podocalyxin: a marker of blasts in acute leukemia. Am J Clin Pathol (2005) 1.06
Role of PELP1/MNAR signaling in ovarian tumorigenesis. Cancer Res (2008) 1.05
Progressive changes in Met-dependent signaling in a human ovarian surface epithelial model of malignant transformation. Exp Cell Res (2004) 1.04
FADD negatively regulates lipopolysaccharide signaling by impairing interleukin-1 receptor-associated kinase 1-MyD88 interaction. Mol Cell Biol (2007) 1.04
Bacterial lipopolysaccharide directly induces angiogenesis through TRAF6-mediated activation of NF-kappaB and c-Jun N-terminal kinase. Blood (2003) 1.03
Lipopolysaccharide signals an endothelial apoptosis pathway through TNF receptor-associated factor 6-mediated activation of c-Jun NH2-terminal kinase. J Immunol (2002) 1.03
ETV6-NTRK3-mediated breast epithelial cell transformation is blocked by targeting the IGF1R signaling pathway. Cancer Res (2010) 1.02
Co-ordinating Notch, BMP, and TGF-β signaling during heart valve development. Cell Mol Life Sci (2012) 1.01
Cofilin-mediated F-actin severing is regulated by the Rap GTPase and controls the cytoskeletal dynamics that drive lymphocyte spreading and BCR microcluster formation. J Immunol (2011) 1.00
Notch-dependent cell cycle arrest is associated with downregulation of minichromosome maintenance proteins. Circ Res (2005) 0.99
Activation of vascular endothelial growth factor receptor-2 in bone marrow leads to accumulation of myeloid cells: role of granulocyte-macrophage colony-stimulating factor. J Immunol (2005) 0.99
Expression of activated M-Ras in a murine mammary epithelial cell line induces epithelial-mesenchymal transition and tumorigenesis. Oncogene (2004) 0.98
Gonadotropins regulate N-cadherin-mediated human ovarian surface epithelial cell survival at both post-translational and transcriptional levels through a cyclic AMP/protein kinase A pathway. J Biol Chem (2005) 0.98
Quantitative analysis of the low molecular weight serum proteome using 18O stable isotope labeling in a lung tumor xenograft mouse model. J Am Soc Mass Spectrom (2005) 0.98
TGF-beta induces serous borderline ovarian tumor cell invasion by activating EMT but triggers apoptosis in low-grade serous ovarian carcinoma cells. PLoS One (2012) 0.97
Notch4-induced inhibition of endothelial sprouting requires the ankyrin repeats and involves signaling through RBP-Jkappa. Blood (2004) 0.97
Microarray and proteomic analysis of breast cancer cell and osteoblast co-cultures: role of osteoblast matrix metalloproteinase (MMP)-13 in bone metastasis. J Biol Chem (2011) 0.97
Notch signaling in the developing cardiovascular system. Am J Physiol Cell Physiol (2007) 0.97
Vascular endothelial growth factor receptor-2 induces survival of hematopoietic progenitor cells. J Biol Chem (2003) 0.96
Modulation of angiogenic phenotype alters tumorigenicity in rat ovarian epithelial cells. Cancer Res (2007) 0.96
Gonadotropins upregulate the epidermal growth factor receptor through activation of mitogen-activated protein kinases and phosphatidyl-inositol-3-kinase in human ovarian surface epithelial cells. Endocr Relat Cancer (2005) 0.96
EGF-induced EMT and invasiveness in serous borderline ovarian tumor cells: a possible step in the transition to low-grade serous carcinoma cells? PLoS One (2012) 0.95
Differentiation of vascular smooth muscle cells from local precursors during embryonic and adult arteriogenesis requires Notch signaling. Proc Natl Acad Sci U S A (2012) 0.95
Preventing the activation or cycling of the Rap1 GTPase alters adhesion and cytoskeletal dynamics and blocks metastatic melanoma cell extravasation into the lungs. Cancer Res (2010) 0.95
Neopetrosiamides, peptides from the marine sponge Neopetrosia sp. that inhibit amoeboid invasion by human tumor cells. Org Lett (2005) 0.95
Activin receptor-like kinase 7 induces apoptosis through up-regulation of Bax and down-regulation of Xiap in normal and malignant ovarian epithelial cell lines. Mol Cancer Res (2006) 0.95
SASH1 is a scaffold molecule in endothelial TLR4 signaling. J Immunol (2013) 0.94
Immunolocalization of gonadotropin-releasing hormone (GnRH)-I, GnRH-II, and type I GnRH receptor during follicular development in the human ovary. J Clin Endocrinol Metab (2006) 0.94
Primary ovarian mucinous carcinoma of intestinal type: significance of pattern of invasion and immunohistochemical expression profile in a series of 31 cases. Int J Gynecol Pathol (2010) 0.93
CL100 expression is down-regulated in advanced epithelial ovarian cancer and its re-expression decreases its malignant potential. Oncogene (2002) 0.93
Normal ovarian surface epithelium. Cancer Treat Res (2002) 0.93
Innate immune signaling in the myelodysplastic syndromes. Hematol Oncol Clin North Am (2010) 0.92
An improved assay to quantitate the invasiveness of cells in modified Boyden chambers. In Vitro Cell Dev Biol Anim (2007) 0.92
Erythropoietin promotes survival of primary human endothelial cells through PI3K-dependent, NF-kappaB-independent upregulation of Bcl-xL. Am J Physiol Heart Circ Physiol (2007) 0.92
Ovarian surface epithelium: family history and early events in ovarian cancer. Reprod Biol Endocrinol (2003) 0.92
Follicle-stimulating hormone activates mitogen-activated protein kinase in preneoplastic and neoplastic ovarian surface epithelial cells. J Clin Endocrinol Metab (2002) 0.92
Ovarian cancer: linking genomics to new target discovery and molecular markers--the way ahead. Adv Exp Med Biol (2008) 0.92
Inhibition of the phosphatidylinositol 3'-kinase pathway promotes autocrine Fas-induced death of phosphatase and tensin homologue-deficient prostate cancer cells. Cancer Res (2006) 0.92
Role of the microenvironment in promoting angiogenesis in acute myeloid leukemia. Am J Hematol (2002) 0.90
Isolation and culture of primary endothelial cells. Methods Mol Biol (2005) 0.90
In vitro model of normal, immortalized ovarian surface epithelial and ovarian cancer cells for chemoprevention of ovarian cancer. Gynecol Oncol (2005) 0.90
Vascularization predicts overall survival and risk of transformation in follicular lymphoma. Haematologica (2010) 0.89
Proteome changes in ovarian epithelial cells derived from women with BRCA1 mutations and family histories of cancer. Mol Cell Proteomics (2004) 0.89
HOXA7 in epithelial ovarian cancer: interrelationships between differentiation and clinical features. Reprod Sci (2007) 0.88
The tumor invasion inhibitor dihydromotuporamine C activates RHO, remodels stress fibers and focal adhesions, and stimulates sodium-proton exchange. Cancer Res (2004) 0.88
A novel subcellular machine contributes to basal junction remodeling in the seminiferous epithelium. Biol Reprod (2013) 0.87
The role of the breast cancer susceptibility gene 1 (BRCA1) in sporadic epithelial ovarian cancer. Reprod Biol Endocrinol (2003) 0.86
Opposing roles for CD34 in B16 melanoma tumor growth alter early stage vasculature and late stage immune cell infiltration. PLoS One (2011) 0.86