Published in Front Genet on November 28, 2013
The immunogenetics of Psoriasis: A comprehensive review. J Autoimmun (2015) 0.95
In vivo gene delivery and stable transduction of nondividing cells by a lentiviral vector. Science (1996) 28.95
Epigenetic regulation of gene expression: how the genome integrates intrinsic and environmental signals. Nat Genet (2003) 25.57
MLL translocations specify a distinct gene expression profile that distinguishes a unique leukemia. Nat Genet (2001) 13.79
Linking DNA methylation and histone modification: patterns and paradigms. Nat Rev Genet (2009) 12.08
MLL translocations, histone modifications and leukaemia stem-cell development. Nat Rev Cancer (2007) 8.17
Loss of genomic methylation causes p53-dependent apoptosis and epigenetic deregulation. Nat Genet (2001) 6.92
Versatile retroviral vectors for potential use in gene therapy. Gene Ther (1994) 5.33
MLL-rearranged leukemia is dependent on aberrant H3K79 methylation by DOT1L. Cancer Cell (2011) 4.56
Microenvironment determines lineage fate in a human model of MLL-AF9 leukemia. Cancer Cell (2008) 3.79
Enhanced self-renewal of hematopoietic stem cells mediated by the polycomb gene product Bmi-1. Immunity (2004) 3.25
Modeling the initiation and progression of human acute leukemia in mice. Science (2007) 2.90
Angiopoietin-like 5 and IGFBP2 stimulate ex vivo expansion of human cord blood hematopoietic stem cells as assayed by NOD/SCID transplantation. Blood (2008) 2.79
Colocalization of retrovirus and target cells on specific fibronectin fragments increases genetic transduction of mammalian cells. Nat Med (1996) 2.73
Epigenetic silencing of the myelopoiesis regulator microRNA-223 by the AML1/ETO oncoprotein. Cancer Cell (2007) 2.55
Epigenetics in cancer: targeting chromatin modifications. Mol Cancer Ther (2009) 2.50
Akt-mediated phosphorylation of Bmi1 modulates its oncogenic potential, E3 ligase activity, and DNA damage repair activity in mouse prostate cancer. J Clin Invest (2012) 2.03
A functional comparison of CD34 + CD38- cells in cord blood and bone marrow. Blood (1995) 1.96
Functional antagonism of the Polycomb-Group genes eed and Bmi1 in hemopoietic cell proliferation. Genes Dev (1999) 1.95
Recent advances in lentiviral vector development and applications. Mol Ther (2010) 1.89
The AML1-ETO fusion protein promotes the expansion of human hematopoietic stem cells. Blood (2002) 1.84
Interplay of RUNX1/MTG8 and DNA methyltransferase 1 in acute myeloid leukemia. Cancer Res (2005) 1.69
Maintaining the self-renewal and differentiation potential of human CD34+ hematopoietic cells using a single genetic element. Blood (2003) 1.59
The leukemogenicity of AML1-ETO is dependent on site-specific lysine acetylation. Science (2011) 1.49
Hematopoietic defects in mice lacking the sialomucin CD34. Blood (1996) 1.46
Genome-wide DNA methylation profiles in hematopoietic stem and progenitor cells reveal overrepresentation of ETS transcription factor binding sites. Genome Res (2012) 1.37
The CD34-related molecule podocalyxin is a potent inducer of microvillus formation. PLoS One (2007) 1.25
Repression of BMI1 in normal and leukemic human CD34(+) cells impairs self-renewal and induces apoptosis. Blood (2009) 1.24
Transcriptional activity of core binding factor-alpha (AML1) and beta subunits on murine leukemia virus enhancer cores. J Virol (1995) 1.22
The stem cell antigen CD34 functions as a regulator of hemopoietic cell adhesion. Proc Natl Acad Sci U S A (1995) 1.14
Epigenetic consequences of AML1-ETO action at the human c-FMS locus. EMBO J (2003) 1.14
ERG and FLI1 binding sites demarcate targets for aberrant epigenetic regulation by AML1-ETO in acute myeloid leukemia. Blood (2012) 1.12
Polycomb-group complex 1 acts as an E3 ubiquitin ligase for Geminin to sustain hematopoietic stem cell activity. Proc Natl Acad Sci U S A (2008) 1.10
Targeting epigenetic programs in MLL-rearranged leukemias. Hematology Am Soc Hematol Educ Program (2011) 1.08
Recent progress toward epigenetic therapies: the example of mixed lineage leukemia. Blood (2013) 1.08
BMI1 collaborates with BCR-ABL in leukemic transformation of human CD34+ cells. Blood (2010) 1.06
p53 binds to and is required for the repression of Arf tumor suppressor by HDAC and polycomb. Cancer Res (2011) 1.04
Role of the polycomb group gene BMI1 in normal and leukemic hematopoietic stem and progenitor cells. Curr Opin Hematol (2010) 1.02
AML1 is functionally regulated through p300-mediated acetylation on specific lysine residues. J Biol Chem (2004) 1.00
Characterization of human amniotic fluid stem cells and their pluripotential capability. Methods Cell Biol (2008) 0.97
Full-length but not truncated CD34 inhibits hematopoietic cell differentiation of M1 cells. Blood (1995) 0.96
Epigenetic regulation of hematopoiesis. Int J Hematol (2012) 0.94
Epigenetic mechanisms in AML - a target for therapy. Cancer Treat Res (2010) 0.92
A simple and quick method to concentrate MSCV retrovirus. Blood Cells Mol Dis (2004) 0.92
Bmi1 confers resistance to oxidative stress on hematopoietic stem cells. PLoS One (2012) 0.91
Retroviral-mediated gene transfer into mammalian cells. Blood Cells (1987) 0.91
N-Ras(G12D) induces features of stepwise transformation in preleukemic human umbilical cord blood cultures expressing the AML1-ETO fusion gene. Blood (2011) 0.91
Role of CD34 antigen in myeloid differentiation of human hematopoietic progenitor cells. Stem Cells (2008) 0.88
Bmi1 reprograms CML B-lymphoid progenitors to become B-ALL-initiating cells. Blood (2011) 0.87
RUNX1/AML1 mutant collaborates with BMI1 overexpression in the development of human and murine myelodysplastic syndromes. Blood (2013) 0.85
Molecular and Epigenetic Mechanisms of MLL in Human Leukemogenesis. Cancers (Basel) (2012) 0.83
Extended in vitro expansion of adult, mobilized CD34+ cells without significant cell senescence using a stromal cell coculture system with single cytokine support. Stem Cells Dev (2009) 0.82
When speed matters: leukemogenic transformation by MLL fusion proteins. Cell Cycle (2010) 0.77
Trithorax and polycomb cooperation in MLL fusion acute leukemia. Haematologica (2013) 0.76
Immunomagnetic cell separation. Methods Mol Med (2001) 0.76