PubRank

John M Shelton

Author PubWeight™ 117.27‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 Histone deacetylase 4 controls chondrocyte hypertrophy during skeletogenesis. Cell 2004 5.80
2 Cardiac autophagy is a maladaptive response to hemodynamic stress. J Clin Invest 2007 5.17
3 Transcriptional coactivator PGC-1 alpha controls the energy state and contractile function of cardiac muscle. Cell Metab 2005 4.65
4 Multiple organ pathology, metabolic abnormalities and impaired homeostasis of reactive oxygen species in Epas1-/- mice. Nat Genet 2003 3.78
5 Activated glycogen synthase-3 beta suppresses cardiac hypertrophy in vivo. Proc Natl Acad Sci U S A 2002 3.27
6 Histone deacetylase degradation and MEF2 activation promote the formation of slow-twitch myofibers. J Clin Invest 2007 3.19
7 Regulation of antibacterial defense in the small intestine by the nuclear bile acid receptor. Proc Natl Acad Sci U S A 2006 3.05
8 MEF2C transcription factor controls chondrocyte hypertrophy and bone development. Dev Cell 2007 2.96
9 Hippo pathway effector Yap promotes cardiac regeneration. Proc Natl Acad Sci U S A 2013 2.76
10 A role for the apoptosis inhibitory factor AIM/Spalpha/Api6 in atherosclerosis development. Cell Metab 2005 2.42
11 Myogenin and class II HDACs control neurogenic muscle atrophy by inducing E3 ubiquitin ligases. Cell 2010 2.22
12 Requirement of protein kinase D1 for pathological cardiac remodeling. Proc Natl Acad Sci U S A 2008 2.12
13 Loss of NFAT5 results in renal atrophy and lack of tonicity-responsive gene expression. Proc Natl Acad Sci U S A 2004 2.12
14 Mice lacking calsarcin-1 are sensitized to calcineurin signaling and show accelerated cardiomyopathy in response to pathological biomechanical stress. Nat Med 2004 2.11
15 Autoimmune epididymoorchitis is essential to the pathogenesis of male-specific spondylarthritis in HLA-B27-transgenic rats. Arthritis Rheum 2012 2.10
16 Autophagy is an adaptive response in desmin-related cardiomyopathy. Proc Natl Acad Sci U S A 2008 2.07
17 Maladaptive role of IL-6 in ischemic acute renal failure. J Am Soc Nephrol 2005 2.07
18 HIF-2alpha regulates murine hematopoietic development in an erythropoietin-dependent manner. Blood 2004 1.99
19 Intracellular protein aggregation is a proximal trigger of cardiomyocyte autophagy. Circulation 2008 1.95
20 Thymosin beta4 mediated PKC activation is essential to initiate the embryonic coronary developmental program and epicardial progenitor cell activation in adult mice in vivo. J Mol Cell Cardiol 2009 1.88
21 microRNA-206 promotes skeletal muscle regeneration and delays progression of Duchenne muscular dystrophy in mice. J Clin Invest 2012 1.84
22 Reactive oxygen species impair sympathetic vasoregulation in skeletal muscle in angiotensin II-dependent hypertension. Hypertension 2006 1.82
23 Essential role of STAT3 in body weight and glucose homeostasis. Mol Cell Biol 2004 1.74
24 Myosin accumulation and striated muscle myopathy result from the loss of muscle RING finger 1 and 3. J Clin Invest 2007 1.70
25 Myomaker is a membrane activator of myoblast fusion and muscle formation. Nature 2013 1.69
26 Metabolic stress-induced activation of FoxO1 triggers diabetic cardiomyopathy in mice. J Clin Invest 2012 1.63
27 Critical roles of the guanylyl cyclase B receptor in endochondral ossification and development of female reproductive organs. Proc Natl Acad Sci U S A 2004 1.55
28 Elevated TCA cycle function in the pathology of diet-induced hepatic insulin resistance and fatty liver. J Lipid Res 2012 1.53
29 Control of facial muscle development by MyoR and capsulin. Science 2002 1.48
30 Calcineurin is necessary for the maintenance but not embryonic development of slow muscle fibers. Mol Cell Biol 2005 1.47
31 Mice lacking microRNA 133a develop dynamin 2–dependent centronuclear myopathy. J Clin Invest 2011 1.43
32 Estrogen-related receptor γ serves a role in blood pressure homeostasis during pregnancy. Mol Endocrinol 2014 1.41
33 TRPC3 channels confer cellular memory of recent neuromuscular activity. Proc Natl Acad Sci U S A 2004 1.32
34 Expression of LRH-1 and SF-1 in the mouse ovary: localization in different cell types correlates with differing function. Mol Cell Endocrinol 2003 1.28
35 Protein kinase D1 stimulates MEF2 activity in skeletal muscle and enhances muscle performance. Mol Cell Biol 2008 1.27
36 The Down syndrome critical region protein RCAN1 regulates long-term potentiation and memory via inhibition of phosphatase signaling. J Neurosci 2007 1.26
37 Characterization of mouse short-chain aldehyde reductase (SCALD), an enzyme regulated by sterol regulatory element-binding proteins. J Biol Chem 2003 1.26
38 Myosin regulatory light chain phosphorylation attenuates cardiac hypertrophy. J Biol Chem 2008 1.23
39 Toll-like receptor 4 regulates early endothelial activation during ischemic acute kidney injury. Kidney Int 2010 1.22
40 Requirement of MEF2A, C, and D for skeletal muscle regeneration. Proc Natl Acad Sci U S A 2014 1.21
41 Neuroglobin, a novel member of the globin family, is expressed in focal regions of the brain. J Histochem Cytochem 2002 1.21
42 Regulation of hyaluronan expression during cervical ripening. Glycobiology 2004 1.21
43 Mitochondrial metabolism mediates oxidative stress and inflammation in fatty liver. J Clin Invest 2015 1.19
44 Deletion of hexose-6-phosphate dehydrogenase activates the unfolded protein response pathway and induces skeletal myopathy. J Biol Chem 2008 1.18
45 Centronuclear myopathy in mice lacking a novel muscle-specific protein kinase transcriptionally regulated by MEF2. Genes Dev 2005 1.13
46 Hand2 controls osteoblast differentiation in the branchial arch by inhibiting DNA binding of Runx2. Development 2009 1.10
47 Loss of muscle-specific RING-finger 3 predisposes the heart to cardiac rupture after myocardial infarction. Proc Natl Acad Sci U S A 2007 1.10
48 Histone deacetylases 1 and 2 regulate autophagy flux and skeletal muscle homeostasis in mice. Proc Natl Acad Sci U S A 2012 1.08
49 Severe myopathy in mice lacking the MEF2/SRF-dependent gene leiomodin-3. J Clin Invest 2015 1.06
50 Normal development and fertility of knockout mice lacking the tumor suppressor gene LRP1b suggest functional compensation by LRP1. Mol Cell Biol 2004 1.05
51 Overexpression of pyruvate dehydrogenase kinase 4 in heart perturbs metabolism and exacerbates calcineurin-induced cardiomyopathy. Am J Physiol Heart Circ Physiol 2007 1.05
52 Functional characterization of mouse RDH11 as a retinol dehydrogenase involved in dark adaptation in vivo. J Biol Chem 2005 1.00
53 Hair growth defects in Insig-deficient mice caused by cholesterol precursor accumulation and reversed by simvastatin. J Invest Dermatol 2010 0.99
54 Ischemia-reperfusion induces G-CSF gene expression by renal medullary thick ascending limb cells in vivo and in vitro. Am J Physiol Renal Physiol 2004 0.98
55 Amino acid substitution in NPC1 that abolishes cholesterol binding reproduces phenotype of complete NPC1 deficiency in mice. Proc Natl Acad Sci U S A 2011 0.97
56 IRF-1 promotes inflammation early after ischemic acute kidney injury. J Am Soc Nephrol 2009 0.96
57 Identification of acyloxyacyl hydrolase, a lipopolysaccharide-detoxifying enzyme, in the murine urinary tract. Infect Immun 2004 0.96
58 Cytoglobin is a stress-responsive hemoprotein expressed in the developing and adult brain. J Histochem Cytochem 2006 0.95
59 Transcriptional regulation of aromatase in placenta and ovary. J Steroid Biochem Mol Biol 2005 0.94
60 Mechanical unloading activates FoxO3 to trigger Bnip3-dependent cardiomyocyte atrophy. J Am Heart Assoc 2013 0.94
61 Diminished cardiac fibrosis in heart failure is associated with altered ventricular arrhythmia phenotype. J Cardiovasc Electrophysiol 2010 0.92
62 Genomic regions that mediate placental cell-specific and developmental regulation of human Cyp19 (aromatase) gene expression in transgenic mice. Endocrinology 2005 0.90
63 Temporal and spatial expression of liver receptor homologue-1 (LRH-1) during embryogenesis suggests a potential role in gonadal development. Dev Dyn 2005 0.89
64 Sustained hemodynamic stress disrupts normal circadian rhythms in calcineurin-dependent signaling and protein phosphorylation in the heart. Circ Res 2011 0.89
65 Disruption of PPT2 in mice causes an unusual lysosomal storage disorder with neurovisceral features. Proc Natl Acad Sci U S A 2003 0.87
66 Cytoglobin modulates myogenic progenitor cell viability and muscle regeneration. Proc Natl Acad Sci U S A 2013 0.87
67 Reactive oxygen species and IRF1 stimulate IFNα production by proximal tubules during ischemic AKI. Am J Physiol Renal Physiol 2013 0.82
68 Laryngeal aging and acoustic changes in male rat ultrasonic vocalizations. Dev Psychobiol 2012 0.79
69 Hypercalcemia of malignancy with simultaneous elevation in serum parathyroid hormone--related peptide and 1,25-dihydroxyvitamin D in a patient with metastatic renal cell carcinoma. Endocr Pract 2009 0.78
70 Mitochondrial metabolism mediates oxidative stress and inflammation in fatty liver. J Clin Invest 2016 0.76
71 Linking spermatid ribonucleic acid (RNA) binding protein and retrogene diversity to reproductive success. Mol Cell Proteomics 2013 0.76
72 Vaginal estrogen: a dual-edged sword in postoperative healing of the vaginal wall. Menopause 2017 0.75
73 Corrigendum: Hypoxia fate mapping identifies cycling cardiomyocytes in the adult heart. Nature 2015 0.75
74 A reevaluation of CD22 expression in human lung cancer. Cancer Res 2014 0.75