Published in Med Image Comput Comput Assist Interv on January 01, 2006
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Genome sequencing of pediatric medulloblastoma links catastrophic DNA rearrangements with TP53 mutations. Cell (2012) 6.07
Mouse polycomb proteins bind differentially to methylated histone H3 and RNA and are enriched in facultative heterochromatin. Mol Cell Biol (2006) 5.99
Epigenetic dynamics of imprinted X inactivation during early mouse development. Science (2003) 5.80
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Dissecting the genomic complexity underlying medulloblastoma. Nature (2012) 4.77
Customized oligonucleotide microarray gene expression-based classification of neuroblastoma patients outperforms current clinical risk stratification. J Clin Oncol (2006) 4.35
Three-dimensional maps of all chromosomes in human male fibroblast nuclei and prometaphase rosettes. PLoS Biol (2005) 4.33
Nuclear architecture of rod photoreceptor cells adapts to vision in mammalian evolution. Cell (2009) 4.23
LINE-1 activity in facultative heterochromatin formation during X chromosome inactivation. Cell (2010) 3.70
Transient colocalization of X-inactivation centres accompanies the initiation of X inactivation. Nat Cell Biol (2006) 3.66
Nuclear envelope breakdown proceeds by microtubule-induced tearing of the lamina. Cell (2002) 3.64
Differentially methylated forms of histone H3 show unique association patterns with inactive human X chromosomes. Nat Genet (2001) 3.63
A novel role for Xist RNA in the formation of a repressive nuclear compartment into which genes are recruited when silenced. Genes Dev (2006) 3.41
Global chromosome positions are transmitted through mitosis in mammalian cells. Cell (2003) 3.27
Automatic identification of subcellular phenotypes on human cell arrays. Genome Res (2004) 3.25
The A- and B-type nuclear lamin networks: microdomains involved in chromatin organization and transcription. Genes Dev (2008) 3.23
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Evidence for de novo imprinted X-chromosome inactivation independent of meiotic inactivation in mice. Nature (2005) 2.46
A contractile nuclear actin network drives chromosome congression in oocytes. Nature (2005) 2.45
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Omic data from evolved E. coli are consistent with computed optimal growth from genome-scale models. Mol Syst Biol (2010) 2.41
Group testing for pathway analysis improves comparability of different microarray datasets. Bioinformatics (2006) 2.37
Cross-platform analysis of cancer microarray data improves gene expression based classification of phenotypes. BMC Bioinformatics (2005) 2.36
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Role of histone methyltransferase G9a in CpG methylation of the Prader-Willi syndrome imprinting center. J Biol Chem (2003) 2.25
Non-random radial arrangements of interphase chromosome territories: evolutionary considerations and functional implications. Mutat Res (2002) 2.24
Inheritance of gene density-related higher order chromatin arrangements in normal and tumor cell nuclei. J Cell Biol (2003) 2.12
X inactivation and the complexities of silencing a sex chromosome. Curr Opin Cell Biol (2009) 2.09
Recurrent mutation of the ID3 gene in Burkitt lymphoma identified by integrated genome, exome and transcriptome sequencing. Nat Genet (2012) 2.07
Chromatin domains and the interchromatin compartment form structurally defined and functionally interacting nuclear networks. Chromosome Res (2006) 2.07
Cohesin-based chromatin interactions enable regulated gene expression within preexisting architectural compartments. Genome Res (2013) 2.05
Genomic analysis of single cytokeratin-positive cells from bone marrow reveals early mutational events in breast cancer. Cancer Cell (2005) 2.03
High-resolution analysis of epigenetic changes associated with X inactivation. Genome Res (2009) 2.02
Visualizing telomere dynamics in living mammalian cells using PNA probes. EMBO J (2003) 1.99
Highly dynamic and sex-specific expression of microRNAs during early ES cell differentiation. PLoS Genet (2009) 1.96
Three-dimensional arrangements of centromeres and telomeres in nuclei of human and murine lymphocytes. Chromosome Res (2003) 1.94
Methyl CpG-binding proteins induce large-scale chromatin reorganization during terminal differentiation. J Cell Biol (2005) 1.91
Large-scale in silico modeling of metabolic interactions between cell types in the human brain. Nat Biotechnol (2010) 1.85
The pluripotent genome in three dimensions is shaped around pluripotency factors. Nature (2013) 1.82
Deterministic and stochastic allele specific gene expression in single mouse blastomeres. PLoS One (2011) 1.82
CCM2 mediates death signaling by the TrkA receptor tyrosine kinase. Neuron (2009) 1.79
GOPET: a tool for automated predictions of Gene Ontology terms. BMC Bioinformatics (2006) 1.75
Common themes and cell type specific variations of higher order chromatin arrangements in the mouse. BMC Cell Biol (2005) 1.75
MicroRNA regulation of Cbx7 mediates a switch of Polycomb orthologs during ESC differentiation. Cell Stem Cell (2012) 1.72
Initial genomics of the human nucleolus. PLoS Genet (2010) 1.71
Dynamics of HIV-1 assembly and release. PLoS Pathog (2009) 1.67
Microarray-based copy number and expression profiling in dedifferentiated and pleomorphic liposarcoma. Cancer Res (2002) 1.64
Prediction of clinical outcome and biological characterization of neuroblastoma by expression profiling. Oncogene (2005) 1.62
Etiology-dependent molecular mechanisms in human hepatocarcinogenesis. Hepatology (2008) 1.62
Metabolic-energy-dependent movement of PML bodies within the mammalian cell nucleus. Nat Cell Biol (2002) 1.60
Dynamics within the CD95 death-inducing signaling complex decide life and death of cells. Mol Syst Biol (2010) 1.57
Integration of activating and inhibitory receptor signaling by regulated phosphorylation of Vav1 in immune cells. Sci Signal (2011) 1.57
Antisense RNA in imprinting: spreading silence through Air. Trends Genet (2002) 1.57
Dynamic changes in paternal X-chromosome activity during imprinted X-chromosome inactivation in mice. Proc Natl Acad Sci U S A (2009) 1.56
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Genome-wide transcriptional analysis of the human cell cycle identifies genes differentially regulated in normal and cancer cells. Proc Natl Acad Sci U S A (2008) 1.53
Multicolor 3D fluorescence in situ hybridization for imaging interphase chromosomes. Methods Mol Biol (2008) 1.52
Concurrent detection of autolysosome formation and lysosomal degradation by flow cytometry in a high-content screen for inducers of autophagy. BMC Biol (2011) 1.51
A highly standardized, robust, and cost-effective method for genome-wide transcriptome analysis of peripheral blood applicable to large-scale clinical trials. Genomics (2006) 1.51
Comparison of normalization methods for Illumina BeadChip HumanHT-12 v3. BMC Genomics (2010) 1.50
Optimal experimental design for parameter estimation of a cell signaling model. PLoS Comput Biol (2009) 1.47
Smchd1-dependent and -independent pathways determine developmental dynamics of CpG island methylation on the inactive X chromosome. Dev Cell (2012) 1.47
Applying Support Vector Machines for Gene Ontology based gene function prediction. BMC Bioinformatics (2004) 1.47
Segmental folding of chromosomes: a basis for structural and regulatory chromosomal neighborhoods? Bioessays (2013) 1.45
Radial chromatin positioning is shaped by local gene density, not by gene expression. Chromosoma (2007) 1.45
Automatic analysis of dividing cells in live cell movies to detect mitotic delays and correlate phenotypes in time. Genome Res (2009) 1.44
RNAither, an automated pipeline for the statistical analysis of high-throughput RNAi screens. Bioinformatics (2009) 1.44
Prognostic impact of gene expression-based classification for neuroblastoma. J Clin Oncol (2010) 1.43
Artesunate activates mitochondrial apoptosis in breast cancer cells via iron-catalyzed lysosomal reactive oxygen species production. J Biol Chem (2010) 1.41