Look who's talking: communication and quorum sensing in the bacterial world.

PubWeight™: 4.24‹?› | Rank: Top 1%

🔗 View Article (PMC 2435577)

Published in Philos Trans R Soc Lond B Biol Sci on July 29, 2007

Authors

Paul Williams1, Klaus Winzer, Weng C Chan, Miguel Cámara

Author Affiliations

1: Institute of Infection, Immunity and Inflammation, Centre for Biomolecular Sciences, School of Molecular Medical Sciences, University of Nottingham, Nottingham NG7 2RD, UK. paul.williams@nottingham.ac.uk

Articles citing this

(truncated to the top 100)

Bacterial quorum-sensing network architectures. Annu Rev Genet (2009) 6.14

Antibiotics as signalling molecules. Philos Trans R Soc Lond B Biol Sci (2007) 2.74

Cooperation and virulence of clinical Pseudomonas aeruginosa populations. Proc Natl Acad Sci U S A (2009) 2.07

Siderophores from neighboring organisms promote the growth of uncultured bacteria. Chem Biol (2010) 2.04

Quorum-quenching microbial infections: mechanisms and implications. Philos Trans R Soc Lond B Biol Sci (2007) 1.85

Density-dependent fitness benefits in quorum-sensing bacterial populations. Proc Natl Acad Sci U S A (2012) 1.83

Characterization of N-acylhomoserine lactone-degrading bacteria associated with the Zingiber officinale (ginger) rhizosphere: co-existence of quorum quenching and quorum sensing in Acinetobacter and Burkholderia. BMC Microbiol (2011) 1.82

Quorum sensing and social networking in the microbial world. J R Soc Interface (2009) 1.76

Quinolones: from antibiotics to autoinducers. FEMS Microbiol Rev (2011) 1.75

Quorum quenching revisited--from signal decays to signalling confusion. Sensors (Basel) (2012) 1.71

Quorum-sensing blockade as a strategy for enhancing host defences against bacterial pathogens. Philos Trans R Soc Lond B Biol Sci (2007) 1.70

Bacterial conversations: talking, listening and eavesdropping. An introduction. Philos Trans R Soc Lond B Biol Sci (2007) 1.64

Expanding dialogues: from natural autoinducers to non-natural analogues that modulate quorum sensing in Gram-negative bacteria. Chem Soc Rev (2008) 1.62

Social evolution in micro-organisms and a Trojan horse approach to medical intervention strategies. Philos Trans R Soc Lond B Biol Sci (2009) 1.53

Characterization of quorum sensing and quorum quenching soil bacteria isolated from Malaysian tropical montane forest. Sensors (Basel) (2012) 1.49

Genomic analysis reveals versatile organisms for quorum quenching enzymes: acyl-homoserine lactone-acylase and -lactonase. Open Microbiol J (2011) 1.49

Quorum-sensing and cheating in bacterial biofilms. Proc Biol Sci (2012) 1.47

Combinatorial discovery of polymers resistant to bacterial attachment. Nat Biotechnol (2012) 1.46

Evolution of virulence in opportunistic pathogens: generalism, plasticity, and control. Trends Microbiol (2012) 1.44

Structural Insights into Streptococcal Competence Regulation by the Cell-to-Cell Communication System ComRS. PLoS Pathog (2016) 1.42

The oligopeptide transport system is essential for the development of natural competence in Streptococcus thermophilus strain LMD-9. J Bacteriol (2009) 1.40

Transcriptome analysis of the Vibrio fischeri LuxR-LuxI regulon. J Bacteriol (2007) 1.34

Identification of catechin as one of the flavonoids from Combretum albiflorum bark extract that reduces the production of quorum-sensing-controlled virulence factors in Pseudomonas aeruginosa PAO1. Appl Environ Microbiol (2009) 1.33

Regulation of neurotoxin production and sporulation by a Putative agrBD signaling system in proteolytic Clostridium botulinum. Appl Environ Microbiol (2010) 1.30

The novel two-component regulatory system BfiSR regulates biofilm development by controlling the small RNA rsmZ through CafA. J Bacteriol (2010) 1.29

N-acyl homoserine lactone production by Klebsiella pneumoniae isolated from human tongue surface. Sensors (Basel) (2012) 1.28

Burkholderia pseudomallei, B. thailandensis, and B. ambifaria produce 4-hydroxy-2-alkylquinoline analogues with a methyl group at the 3 position that is required for quorum-sensing regulation. J Bacteriol (2008) 1.27

Cooperation and cheating in Pseudomonas aeruginosa: the roles of the las, rhl and pqs quorum-sensing systems. ISME J (2011) 1.27

Brominated furanones inhibit biofilm formation by Salmonella enterica serovar Typhimurium. Appl Environ Microbiol (2008) 1.22

Complete genome sequence of the sugarcane nitrogen-fixing endophyte Gluconacetobacter diazotrophicus Pal5. BMC Genomics (2009) 1.22

Bacterial quorum sensing, cooperativity, and anticipation of stationary-phase stress. Proc Natl Acad Sci U S A (2012) 1.22

Quorum-sensing regulation in rhizobia and its role in symbiotic interactions with legumes. Philos Trans R Soc Lond B Biol Sci (2007) 1.21

Quorum sensing in fungi--a review. Med Mycol (2012) 1.21

Microbial communication, cooperation and cheating: quorum sensing drives the evolution of cooperation in bacteria. PLoS One (2009) 1.20

Combinatorial quorum sensing allows bacteria to resolve their social and physical environment. Proc Natl Acad Sci U S A (2014) 1.20

Culturing marine bacteria - an essential prerequisite for biodiscovery. Microb Biotechnol (2010) 1.20

Cross-kingdom signalling: exploitation of bacterial quorum sensing molecules by the green seaweed Ulva. Philos Trans R Soc Lond B Biol Sci (2007) 1.19

Social interactions and distribution of Bacillus subtilis pherotypes at microscale. J Bacteriol (2008) 1.18

Identification of sesquiterpene synthases from Nostoc punctiforme PCC 73102 and Nostoc sp. strain PCC 7120. J Bacteriol (2008) 1.14

Functional analysis of the group A streptococcal luxS/AI-2 system in metabolism, adaptation to stress and interaction with host cells. BMC Microbiol (2008) 1.13

Optimal tuning of bacterial sensing potential. Mol Syst Biol (2009) 1.12

Pantoea sp. isolated from tropical fresh water exhibiting N-acyl homoserine lactone production. ScientificWorldJournal (2014) 1.10

An agr quorum sensing system that regulates granulose formation and sporulation in Clostridium acetobutylicum. Appl Environ Microbiol (2011) 1.10

Interactions of the algicidal bacterium Kordia algicida with diatoms: regulated protease excretion for specific algal lysis. PLoS One (2011) 1.09

A mutational analysis defines Vibrio fischeri LuxR binding sites. J Bacteriol (2007) 1.09

What's in a name? The semantics of quorum sensing. Trends Microbiol (2010) 1.08

Complete Genome Sequence of Pseudomonas aeruginosa Strain YL84, a Quorum-Sensing Strain Isolated from Compost. Genome Announc (2014) 1.07

The cognitive cell: bacterial behavior reconsidered. Front Microbiol (2015) 1.05

Plasmodium falciparum gametocyte development 1 (Pfgdv1) and gametocytogenesis early gene identification and commitment to sexual development. PLoS Pathog (2012) 1.05

Pseudomonas aeruginosa adapts its iron uptake strategies in function of the type of infections. Front Cell Infect Microbiol (2013) 1.04

Switching between apparently redundant iron-uptake mechanisms benefits bacteria in changeable environments. Proc Biol Sci (2013) 1.04

Detection of quorum sensing signal molecules and identification of an autoinducer synthase gene among biofilm forming clinical isolates of Acinetobacter spp. PLoS One (2012) 1.03

Microbial telesensing: probing the environment for friends, foes, and food. Cell Host Microbe (2009) 1.03

Quorum-quenching acylase reduces the virulence of Pseudomonas aeruginosa in a Caenorhabditis elegans infection model. Antimicrob Agents Chemother (2009) 1.03

Microbial activities and intestinal homeostasis: A delicate balance between health and disease. Cell Mol Gastroenterol Hepatol (2015) 1.00

Polyamines are required for the expression of key Hms proteins important for Yersinia pestis biofilm formation. Environ Microbiol (2010) 0.99

Cooperation, quorum sensing, and evolution of virulence in Staphylococcus aureus. Infect Immun (2013) 0.99

The chemical ecology of cyanobacteria. Nat Prod Rep (2012) 0.98

Physiological framework for the regulation of quorum sensing-dependent public goods in Pseudomonas aeruginosa. J Bacteriol (2013) 0.96

Distinct growth strategies of soil bacteria as revealed by large-scale colony tracking. Appl Environ Microbiol (2011) 0.96

Discovery of Pantoea rodasii strain ND03 that produces N-(3-Oxo-hexanoyl)-L-homoserine lactone. Sensors (Basel) (2014) 0.96

Can the natural diversity of quorum-sensing advance synthetic biology? Front Bioeng Biotechnol (2015) 0.96

Bacterial attraction and quorum sensing inhibition in Caenorhabditis elegans exudates. J Chem Ecol (2009) 0.95

Structural basis for native agonist and synthetic inhibitor recognition by the Pseudomonas aeruginosa quorum sensing regulator PqsR (MvfR). PLoS Pathog (2013) 0.95

Biomolecular Mechanisms of Pseudomonas aeruginosa and Escherichia coli Biofilm Formation. Pathogens (2014) 0.95

Discovery of novel materials with broad resistance to bacterial attachment using combinatorial polymer microarrays. Adv Mater (2013) 0.94

4-Quinolones: smart phones of the microbial world. Chem Rev (2010) 0.94

Kin selection, quorum sensing and virulence in pathogenic bacteria. Proc Biol Sci (2012) 0.94

Horizontal gene transfer in osmotrophs: playing with public goods. Nat Rev Microbiol (2013) 0.94

Quadruple quorum-sensing inputs control Vibrio cholerae virulence and maintain system robustness. PLoS Pathog (2015) 0.93

Unusual long-chain N-acyl homoserine lactone production by and presence of quorum quenching activity in bacterial isolates from diseased tilapia fish. PLoS One (2012) 0.93

Engineering multicellular systems by cell-cell communication. Curr Opin Biotechnol (2009) 0.92

Pseudomonas cremoricolorata strain ND07 produces N-acyl homoserine lactones as quorum sensing molecules. Sensors (Basel) (2014) 0.92

Insights into the Quorum-Sensing Activity in Aeromonas hydrophila Strain M013 as Revealed by Whole-Genome Sequencing. Genome Announc (2015) 0.92

Selective and tunable gradient device for cell culture and chemotaxis study. Lab Chip (2009) 0.92

Freshwater-borne bacteria isolated from a Malaysian rainforest waterfall exhibiting quorum sensing properties. Sensors (Basel) (2014) 0.92

Bacteria clustering by polymers induces the expression of quorum-sensing-controlled phenotypes. Nat Chem (2013) 0.91

Insights of biosurfactant producing Serratia marcescens strain W2.3 isolated from diseased tilapia fish: a draft genome analysis. Gut Pathog (2013) 0.91

Targeting Staphylococcus aureus quorum sensing with nonpeptidic small molecule inhibitors. J Med Chem (2014) 0.91

Conversation game: talking bacteria. J Cell Commun Signal (2016) 0.91

Exploring the metabolic network of the epidemic pathogen Burkholderia cenocepacia J2315 via genome-scale reconstruction. BMC Syst Biol (2011) 0.91

Degradation of bacterial quorum sensing signaling molecules by the microscopic yeast Trichosporon loubieri isolated from tropical wetland waters. Sensors (Basel) (2013) 0.90

Complete Genome Sequence of Pandoraea pnomenusa 3kgm, a Quorum-Sensing Strain Isolated from a Former Landfill Site. Genome Announc (2014) 0.90

The Evolution of Quorum Sensing as a Mechanism to Infer Kinship. PLoS Comput Biol (2016) 0.90

Novel approaches to the treatment of Pseudomonas aeruginosa infections in cystic fibrosis. Eur Respir J (2012) 0.89

Collective sensing and collective responses in quorum-sensing bacteria. J R Soc Interface (2015) 0.89

War and peace: social interactions in infections. Philos Trans R Soc Lond B Biol Sci (2014) 0.88

Spite versus cheats: competition among social strategies shapes virulence in Pseudomonas aeruginosa. Evolution (2012) 0.88

Phylogenetically novel LuxI/LuxR-type quorum sensing systems isolated using a metagenomic approach. Appl Environ Microbiol (2012) 0.87

Combinatorial communication in bacteria: implications for the origins of linguistic generativity. PLoS One (2014) 0.86

Sub-MICs of Mentha piperita essential oil and menthol inhibits AHL mediated quorum sensing and biofilm of Gram-negative bacteria. Front Microbiol (2015) 0.86

Directed evolution of the quorum-sensing regulator EsaR for increased signal sensitivity. ACS Chem Biol (2013) 0.85

Disruption of bacterial cell-to-cell communication by marine organisms and its relevance to aquaculture. Mar Biotechnol (NY) (2011) 0.85

Quorum sensing triggers the stochastic escape of individual cells from Pseudomonas putida biofilms. Nat Commun (2015) 0.85

Metagenomic approaches to understanding phylogenetic diversity in quorum sensing. Virulence (2014) 0.85

Biofilm development on Caenorhabditis elegans by Yersinia is facilitated by quorum sensing-dependent repression of type III secretion. PLoS Pathog (2011) 0.85

Long chain N-acyl homoserine lactone production by Enterobacter sp. isolated from human tongue surfaces. Sensors (Basel) (2012) 0.85

Nitrite-Oxidizing Bacterium Nitrobacter winogradskyi Produces N-Acyl-Homoserine Lactone Autoinducers. Appl Environ Microbiol (2015) 0.85

The role of quorum sensing signalling in EPS production and the assembly of a sludge community into aerobic granules. ISME J (2014) 0.84

Characterisation of a marine bacterium Vibrio brasiliensis T33 producing N-acyl homoserine lactone quorum sensing molecules. Sensors (Basel) (2014) 0.84

Articles cited by this

(truncated to the top 100)

Quorum sensing in bacteria: the LuxR-LuxI family of cell density-responsive transcriptional regulators. J Bacteriol (1994) 17.55

Structural identification of autoinducer of Photobacterium fischeri luciferase. Biochemistry (1981) 11.48

Structure of the autoinducer required for expression of Pseudomonas aeruginosa virulence genes. Proc Natl Acad Sci U S A (1994) 11.44

Expression of Pseudomonas aeruginosa virulence genes requires cell-to-cell communication. Science (1993) 10.85

Cellular control of the synthesis and activity of the bacterial luminescent system. J Bacteriol (1970) 10.35

Cloning and characterization of the Pseudomonas aeruginosa lasR gene, a transcriptional activator of elastase expression. J Bacteriol (1991) 9.89

The small RNA chaperone Hfq and multiple small RNAs control quorum sensing in Vibrio harveyi and Vibrio cholerae. Cell (2004) 8.89

Identification, timing, and signal specificity of Pseudomonas aeruginosa quorum-controlled genes: a transcriptome analysis. J Bacteriol (2003) 8.11

Bacterial interference caused by autoinducing peptide variants. Science (1997) 7.96

Quorum sensing and Chromobacterium violaceum: exploitation of violacein production and inhibition for the detection of N-acylhomoserine lactones. Microbiology (1997) 7.83

Regulation of gene expression by cell-to-cell communication: acyl-homoserine lactone quorum sensing. Annu Rev Genet (2001) 7.63

Intercellular signalling in Vibrio harveyi: sequence and function of genes regulating expression of luminescence. Mol Microbiol (1993) 7.03

Agrobacterium conjugation and gene regulation by N-acyl-L-homoserine lactones. Nature (1993) 6.55

The LuxS family of bacterial autoinducers: biosynthesis of a novel quorum-sensing signal molecule. Mol Microbiol (2001) 6.27

Cell density control of staphylococcal virulence mediated by an octapeptide pheromone. Proc Natl Acad Sci U S A (1995) 6.13

A hierarchical quorum-sensing cascade in Pseudomonas aeruginosa links the transcriptional activators LasR and RhIR (VsmR) to expression of the stationary-phase sigma factor RpoS. Mol Microbiol (1996) 6.07

Bacterial quorum sensing in pathogenic relationships. Infect Immun (2000) 5.92

Attenuation of Pseudomonas aeruginosa virulence by quorum sensing inhibitors. EMBO J (2003) 5.78

Quinolone signaling in the cell-to-cell communication system of Pseudomonas aeruginosa. Proc Natl Acad Sci U S A (1999) 5.58

Transcription profiling-based identification of Staphylococcus aureus genes regulated by the agr and/or sarA loci. J Bacteriol (2001) 5.57

Purification and structural identification of an autoinducer for the luminescence system of Vibrio harveyi. J Biol Chem (1989) 5.55

Detecting and characterizing N-acyl-homoserine lactone signal molecules by thin-layer chromatography. Proc Natl Acad Sci U S A (1997) 5.39

The lux autoinducer regulates the production of exoenzyme virulence determinants in Erwinia carotovora and Pseudomonas aeruginosa. EMBO J (1993) 5.35

Multiple homologues of LuxR and LuxI control expression of virulence determinants and secondary metabolites through quorum sensing in Pseudomonas aeruginosa PAO1. Mol Microbiol (1995) 5.12

Parallel quorum sensing systems converge to regulate virulence in Vibrio cholerae. Cell (2002) 5.12

Enzymatic synthesis of a quorum-sensing autoinducer through use of defined substrates. Science (1996) 4.86

Pheromones': a new term for a class of biologically active substances. Nature (1959) 4.84

Multiple N-acyl-L-homoserine lactone signal molecules regulate production of virulence determinants and secondary metabolites in Pseudomonas aeruginosa. Proc Natl Acad Sci U S A (1995) 4.77

A general role for the lux autoinducer in bacterial cell signalling: control of antibiotic biosynthesis in Erwinia. Gene (1992) 4.56

How bacteria talk to each other: regulation of gene expression by quorum sensing. Curr Opin Microbiol (1999) 4.54

Communication in bacteria: an ecological and evolutionary perspective. Nat Rev Microbiol (2006) 4.44

Quorum sensing controls expression of the type III secretion gene transcription and protein secretion in enterohemorrhagic and enteropathogenic Escherichia coli. Proc Natl Acad Sci U S A (1999) 4.42

Bacteria-host communication: the language of hormones. Proc Natl Acad Sci U S A (2003) 4.38

Construction and analysis of luxCDABE-based plasmid sensors for investigating N-acyl homoserine lactone-mediated quorum sensing. FEMS Microbiol Lett (1998) 4.36

The global activator GacA of Pseudomonas aeruginosa PAO positively controls the production of the autoinducer N-butyryl-homoserine lactone and the formation of the virulence factors pyocyanin, cyanide, and lipase. Mol Microbiol (1997) 4.33

QscR, a modulator of quorum-sensing signal synthesis and virulence in Pseudomonas aeruginosa. Proc Natl Acad Sci U S A (2001) 3.96

Structure-activity analysis of synthetic autoinducing thiolactone peptides from Staphylococcus aureus responsible for virulence. Proc Natl Acad Sci U S A (1999) 3.79

LuxS quorum sensing: more than just a numbers game. Curr Opin Microbiol (2003) 3.76

Quorum sensing Escherichia coli regulators B and C (QseBC): a novel two-component regulatory system involved in the regulation of flagella and motility by quorum sensing in E. coli. Mol Microbiol (2002) 3.48

Autoregulation of nisin biosynthesis in Lactococcus lactis by signal transduction. J Biol Chem (1995) 3.46

Quorum sensing is a global regulatory mechanism in enterohemorrhagic Escherichia coli O157:H7. J Bacteriol (2001) 3.43

N-(3-oxohexanoyl)-L-homoserine lactone regulates carbapenem antibiotic production in Erwinia carotovora. Biochem J (1992) 3.40

Salmonella typhimurium recognizes a chemically distinct form of the bacterial quorum-sensing signal AI-2. Mol Cell (2004) 3.36

Three parallel quorum-sensing systems regulate gene expression in Vibrio harveyi. J Bacteriol (2004) 3.30

A network of networks: quorum-sensing gene regulation in Pseudomonas aeruginosa. Int J Med Microbiol (2006) 3.26

Making 'sense' of metabolism: autoinducer-2, LuxS and pathogenic bacteria. Nat Rev Microbiol (2005) 3.20

Is quorum sensing a side effect of diffusion sensing? Trends Microbiol (2002) 3.18

The Pseudomonas aeruginosa quorum-sensing signal molecule N-(3-oxododecanoyl)-L-homoserine lactone has immunomodulatory activity. Infect Immun (1998) 3.16

The LuxS-dependent autoinducer AI-2 controls the expression of an ABC transporter that functions in AI-2 uptake in Salmonella typhimurium. Mol Microbiol (2001) 3.15

Autoinducer 2 controls biofilm formation in Escherichia coli through a novel motility quorum-sensing regulator (MqsR, B3022). J Bacteriol (2006) 3.14

Vfr controls quorum sensing in Pseudomonas aeruginosa. J Bacteriol (1997) 3.10

A novel strategy for the isolation of luxI homologues: evidence for the widespread distribution of a LuxR:LuxI superfamily in enteric bacteria. Mol Microbiol (1993) 3.09

Acyl homoserine-lactone quorum-sensing signal generation. Proc Natl Acad Sci U S A (1999) 3.07

A Pseudomonas aeruginosa quorum-sensing molecule influences Candida albicans morphology. Mol Microbiol (2004) 3.05

N-acylhomoserine lactones undergo lactonolysis in a pH-, temperature-, and acyl chain length-dependent manner during growth of Yersinia pseudotuberculosis and Pseudomonas aeruginosa. Infect Immun (2002) 3.00

Characterization of the Lactococcus lactis nisin A operon genes nisP, encoding a subtilisin-like serine protease involved in precursor processing, and nisR, encoding a regulatory protein involved in nisin biosynthesis. J Bacteriol (1993) 2.84

Control of the competent state in Pneumococcus by a hormone-like cell product: an example for a new type of regulatory mechanism in bacteria. Nature (1965) 2.84

Recognition of host immune activation by Pseudomonas aeruginosa. Science (2005) 2.84

The global posttranscriptional regulator RsmA modulates production of virulence determinants and N-acylhomoserine lactones in Pseudomonas aeruginosa. J Bacteriol (2001) 2.76

The Pseudomonas aeruginosa quinolone signal molecule overcomes the cell density-dependency of the quorum sensing hierarchy, regulates rhl-dependent genes at the onset of stationary phase and can be produced in the absence of LasR. Mol Microbiol (2003) 2.74

Quorum-sensing inhibitors as anti-pathogenic drugs. Int J Med Microbiol (2006) 2.68

Regulation of uptake and processing of the quorum-sensing autoinducer AI-2 in Escherichia coli. J Bacteriol (2005) 2.64

The Pseudomonas aeruginosa RpoS regulon and its relationship to quorum sensing. Mol Microbiol (2004) 2.63

LuxS: its role in central metabolism and the in vitro synthesis of 4-hydroxy-5-methyl-3(2H)-furanone. Microbiology (2002) 2.61

Quorum sensing regulates type III secretion in Vibrio harveyi and Vibrio parahaemolyticus. J Bacteriol (2004) 2.55

Interspecies communication in bacteria. J Clin Invest (2003) 2.55

gfp-based N-acyl homoserine-lactone sensor systems for detection of bacterial communication. Appl Environ Microbiol (2001) 2.50

Transcriptional control of the hydrogen cyanide biosynthetic genes hcnABC by the anaerobic regulator ANR and the quorum-sensing regulators LasR and RhlR in Pseudomonas aeruginosa. J Bacteriol (2000) 2.48

Lsr-mediated transport and processing of AI-2 in Salmonella typhimurium. Mol Microbiol (2003) 2.47

Developmental biology of Myxococcus. J Bacteriol (1962) 2.46

Pseudomonas aeruginosa cell-to-cell signaling is required for virulence in a model of acute pulmonary infection. Infect Immun (2000) 2.40

Activity of purified QscR, a Pseudomonas aeruginosa orphan quorum-sensing transcription factor. Mol Microbiol (2006) 2.38

Stringent response activates quorum sensing and modulates cell density-dependent gene expression in Pseudomonas aeruginosa. J Bacteriol (2001) 2.37

Advancing the quorum in Pseudomonas aeruginosa: MvaT and the regulation of N-acylhomoserine lactone production and virulence gene expression. J Bacteriol (2002) 2.34

Bacterial cell-to-cell communication: sorry, can't talk now - gone to lunch! Curr Opin Microbiol (2002) 2.31

Positive control of swarming, rhamnolipid synthesis, and lipase production by the posttranscriptional RsmA/RsmZ system in Pseudomonas aeruginosa PAO1. J Bacteriol (2004) 2.25

Regulation of quorum sensing in Pseudomonas. FEMS Microbiol Rev (2006) 2.24

Pseudomonas aeruginosa tolerance to tobramycin, hydrogen peroxide and polymorphonuclear leukocytes is quorum-sensing dependent. Microbiology (2005) 2.24

SdiA of Salmonella enterica is a LuxR homolog that detects mixed microbial communities. J Bacteriol (2001) 2.23

Gelatinase biosynthesis-activating pheromone: a peptide lactone that mediates a quorum sensing in Enterococcus faecalis. Mol Microbiol (2001) 2.22

The Pseudomonas aeruginosa lectins PA-IL and PA-IIL are controlled by quorum sensing and by RpoS. J Bacteriol (2000) 2.22

Bacterial social engagements. Trends Cell Biol (2004) 2.17

Cell-to-cell signalling in Escherichia coli and Salmonella enterica. Mol Microbiol (2004) 2.15

RsaL, a novel repressor of virulence gene expression in Pseudomonas aeruginosa. J Bacteriol (1999) 2.14

agr expression precedes escape of internalized Staphylococcus aureus from the host endosome. Infect Immun (2001) 2.11

Quorum sensing as a population-density-dependent determinant of bacterial physiology. Adv Microb Physiol (2001) 1.99

Structure of the pheromone peptide of the Staphylococcus epidermidis agr system. FEBS Lett (1998) 1.96

Regulation of LuxPQ receptor activity by the quorum-sensing signal autoinducer-2. Mol Cell (2005) 1.94

Synthetic analogues of the bacterial signal (quorum sensing) molecule N-(3-oxododecanoyl)-L-homoserine lactone as immune modulators. J Med Chem (2003) 1.94

Structural basis and specificity of acyl-homoserine lactone signal production in bacterial quorum sensing. Mol Cell (2002) 1.92

Quorum sensing as an integral component of gene regulatory networks in Gram-negative bacteria. Curr Opin Microbiol (2001) 1.90

Structure of the Bacillus subtilis quorum-sensing peptide pheromone ComX. Nat Chem Biol (2005) 1.86

Key determinants of receptor activation in the agr autoinducing peptides of Staphylococcus aureus. Biochemistry (2002) 1.84

Differential regulation of twitching motility and elastase production by Vfr in Pseudomonas aeruginosa. J Bacteriol (2002) 1.82

Bacteriocin small of Rhizobium leguminosarum belongs to the class of N-acyl-L-homoserine lactone molecules, known as autoinducers and as quorum sensing co-transcription factors. J Bacteriol (1996) 1.79

Regulation of Vibrio vulnificus virulence by the LuxS quorum-sensing system. Mol Microbiol (2003) 1.76

pfs-dependent regulation of autoinducer 2 production in Salmonella enterica serovar Typhimurium. J Bacteriol (2002) 1.76

Small molecule-mediated density-dependent control of gene expression in prokaryotes: bioluminescence and the biosynthesis of carbapenem antibiotics. FEMS Microbiol Lett (1992) 1.76

Acyl-homoserine lactone production is more common among plant-associated Pseudomonas spp. than among soilborne Pseudomonas spp. Appl Environ Microbiol (2001) 1.74

Structure of the Escherichia coli quorum sensing protein SdiA: activation of the folding switch by acyl homoserine lactones. J Mol Biol (2005) 1.74

Articles by these authors

Retracted Cell-cell signaling in Xanthomonas campestris involves an HD-GYP domain protein that functions in cyclic di-GMP turnover. Proc Natl Acad Sci U S A (2006) 4.92

Making 'sense' of metabolism: autoinducer-2, LuxS and pathogenic bacteria. Nat Rev Microbiol (2005) 3.20

N-acylhomoserine lactones undergo lactonolysis in a pH-, temperature-, and acyl chain length-dependent manner during growth of Yersinia pseudotuberculosis and Pseudomonas aeruginosa. Infect Immun (2002) 3.00

The Pseudomonas aeruginosa quinolone signal molecule overcomes the cell density-dependency of the quorum sensing hierarchy, regulates rhl-dependent genes at the onset of stationary phase and can be produced in the absence of LasR. Mol Microbiol (2003) 2.74

Quorum sensing and environmental adaptation in Pseudomonas aeruginosa: a tale of regulatory networks and multifunctional signal molecules. Curr Opin Microbiol (2009) 2.64

Advancing the quorum in Pseudomonas aeruginosa: MvaT and the regulation of N-acylhomoserine lactone production and virulence gene expression. J Bacteriol (2002) 2.34

Positive control of swarming, rhamnolipid synthesis, and lipase production by the posttranscriptional RsmA/RsmZ system in Pseudomonas aeruginosa PAO1. J Bacteriol (2004) 2.25

The Pseudomonas aeruginosa 4-quinolone signal molecules HHQ and PQS play multifunctional roles in quorum sensing and iron entrapment. Chem Biol (2007) 2.05

Functional genetic analysis reveals a 2-Alkyl-4-quinolone signaling system in the human pathogen Burkholderia pseudomallei and related bacteria. Chem Biol (2006) 2.03

Density-dependent fitness benefits in quorum-sensing bacterial populations. Proc Natl Acad Sci U S A (2012) 1.83

Characterization of N-acylhomoserine lactone-degrading bacteria associated with the Zingiber officinale (ginger) rhizosphere: co-existence of quorum quenching and quorum sensing in Acinetobacter and Burkholderia. BMC Microbiol (2011) 1.82

Quorum quenching by an N-acyl-homoserine lactone acylase from Pseudomonas aeruginosa PAO1. Infect Immun (2006) 1.77

Quinolones: from antibiotics to autoinducers. FEMS Microbiol Rev (2011) 1.75

4-quinolone signalling in Pseudomonas aeruginosa: old molecules, new perspectives. Int J Med Microbiol (2006) 1.65

Direct detection of N-acylhomoserine lactones in cystic fibrosis sputum. FEMS Microbiol Lett (2002) 1.65

The galactophilic lectin, LecA, contributes to biofilm development in Pseudomonas aeruginosa. Environ Microbiol (2006) 1.56

Integration of DNA into bacterial chromosomes from plasmids without a counter-selection marker. Nucleic Acids Res (2012) 1.47

Sugar synthesis in a protocellular model leads to a cell signalling response in bacteria. Nat Chem (2009) 1.46

Simultaneous quantitative profiling of N-acyl-L-homoserine lactone and 2-alkyl-4(1H)-quinolone families of quorum-sensing signaling molecules using LC-MS/MS. Anal Bioanal Chem (2010) 1.45

Cell-to-cell communication across the prokaryote-eukaryote boundary. Science (2002) 1.45

The MexGHI-OpmD multidrug efflux pump controls growth, antibiotic susceptibility and virulence in Pseudomonas aeruginosa via 4-quinolone-dependent cell-to-cell communication. Microbiology (2005) 1.43

LuxS-dependent quorum sensing in Porphyromonas gingivalis modulates protease and haemagglutinin activities but is not essential for virulence. Microbiology (2002) 1.43

VanT, a homologue of Vibrio harveyi LuxR, regulates serine, metalloprotease, pigment, and biofilm production in Vibrio anguillarum. J Bacteriol (2002) 1.43

N-Acylhomoserine lactone quorum-sensing molecules are modified and degraded by Rhodococcus erythropolis W2 by both amidolytic and novel oxidoreductase activities. Microbiology (2005) 1.35

N-acylhomoserine lactones antagonize virulence gene expression and quorum sensing in Staphylococcus aureus. Infect Immun (2006) 1.35

Inhibition and dispersion of Pseudomonas aeruginosa biofilms by glycopeptide dendrimers targeting the fucose-specific lectin LecB. Chem Biol (2008) 1.34

Biofilm formation in Pseudomonas aeruginosa: fimbrial cup gene clusters are controlled by the transcriptional regulator MvaT. J Bacteriol (2004) 1.32

Methicillin resistance reduces the virulence of healthcare-associated methicillin-resistant Staphylococcus aureus by interfering with the agr quorum sensing system. J Infect Dis (2012) 1.32

Regulation of neurotoxin production and sporulation by a Putative agrBD signaling system in proteolytic Clostridium botulinum. Appl Environ Microbiol (2010) 1.30

Functional analysis of luxS in Staphylococcus aureus reveals a role in metabolism but not quorum sensing. J Bacteriol (2006) 1.27

Differential recognition of Staphylococcus aureus quorum-sensing signals depends on both extracellular loops 1 and 2 of the transmembrane sensor AgrC. J Mol Biol (2008) 1.23

Attenuating Staphylococcus aureus virulence gene regulation: a medicinal chemistry perspective. J Med Chem (2013) 1.20

Quorum sensing and the confusion about diffusion. Trends Microbiol (2012) 1.19

Comprehensive profiling of N-acylhomoserine lactones produced by Yersinia pseudotuberculosis using liquid chromatography coupled to hybrid quadrupole-linear ion trap mass spectrometry. Anal Bioanal Chem (2006) 1.18

Quorum sensing in Yersinia enterocolitica controls swimming and swarming motility. J Bacteriol (2006) 1.16

Transcriptomic analysis reveals a global alkyl-quinolone-independent regulatory role for PqsE in facilitating the environmental adaptation of Pseudomonas aeruginosa to plant and animal hosts. Environ Microbiol (2010) 1.14

A distinctive dual-channel quorum-sensing system operates in Vibrio anguillarum. Mol Microbiol (2004) 1.10

An agr quorum sensing system that regulates granulose formation and sporulation in Clostridium acetobutylicum. Appl Environ Microbiol (2011) 1.10

Disruption of quorum sensing in seawater abolishes attraction of zoospores of the green alga Ulva to bacterial biofilms. Environ Microbiol (2005) 1.08

Quorum quenching activity in Anabaena sp. PCC 7120: identification of AiiC, a novel AHL-acylase. FEMS Microbiol Lett (2008) 1.07

Quorum sensing regulates dpsA and the oxidative stress response in Burkholderia pseudomallei. Microbiology (2006) 1.07

A dual biosensor for 2-alkyl-4-quinolone quorum-sensing signal molecules. Environ Microbiol (2007) 1.05

Acylhomoserine lactone production and degradation by the fish pathogen Tenacibaculum maritimum, a member of the Cytophaga-Flavobacterium-Bacteroides (CFB) group. FEMS Microbiol Lett (2010) 1.03

Functional analysis of the post-transcriptional regulator RsmA reveals a novel RNA-binding site. J Mol Biol (2005) 1.03

Phenotypic and genome-wide analysis of an antibiotic-resistant small colony variant (SCV) of Pseudomonas aeruginosa. PLoS One (2011) 1.03

Quorum sensing in Vibrio cholerae. Nat Genet (2002) 1.03

Biosensor-based assays for PQS, HHQ and related 2-alkyl-4-quinolone quorum sensing signal molecules. Nat Protoc (2007) 1.02

Molecular mechanism of target recognition by subtilin, a class I lanthionine antibiotic. Antimicrob Agents Chemother (2007) 1.02

Autoinducer 2 activity in Escherichia coli culture supernatants can be actively reduced despite maintenance of an active synthase, LuxS. Microbiology (2003) 1.02

Garlic as an inhibitor of Pseudomonas aeruginosa quorum sensing in cystic fibrosis--a pilot randomized controlled trial. Pediatr Pulmonol (2010) 1.00

Turnover of quorum sensing signal molecules modulates cross-kingdom signalling. Environ Microbiol (2009) 1.00

Modulation of pRB/E2F functions in the regulation of cell cycle and in cancer. Curr Cancer Drug Targets (2005) 1.00

Growth deficiencies of Neisseria meningitidis pfs and luxS mutants are not due to inactivation of quorum sensing. J Bacteriol (2008) 0.98

Significant immunomodulatory effects of Pseudomonas aeruginosa quorum-sensing signal molecules: possible link in human sepsis. Clin Sci (Lond) (2008) 0.98

AI-2 does not function as a quorum sensing molecule in Campylobacter jejuni during exponential growth in vitro. BMC Microbiol (2009) 0.96

Pathogen espionage: multiple bacterial adrenergic sensors eavesdrop on host communication systems. Mol Microbiol (2012) 0.95

Structural basis for native agonist and synthetic inhibitor recognition by the Pseudomonas aeruginosa quorum sensing regulator PqsR (MvfR). PLoS Pathog (2013) 0.95

Bursting the bubble on bacterial biofilms: a flow cell methodology. Biofouling (2012) 0.95

The Gac/Rsm and cyclic-di-GMP signalling networks coordinately regulate iron uptake in Pseudomonas aeruginosa. Environ Microbiol (2013) 0.94

Quorum sensing. Curr Biol (2007) 0.93

Evolving cell models for systems and synthetic biology. Syst Synth Biol (2010) 0.93

A glycopeptide dendrimer inhibitor of the galactose-specific lectin LecA and of Pseudomonas aeruginosa biofilms. Angew Chem Int Ed Engl (2011) 0.93

Functional interplay between the Yersinia pseudotuberculosis YpsRI and YtbRI quorum sensing systems modulates swimming motility by controlling expression of flhDC and fliA. Mol Microbiol (2008) 0.93

Targeted mutagenesis of the Clostridium acetobutylicum acetone-butanol-ethanol fermentation pathway. Metab Eng (2012) 0.92

Transgenic tomato plants alter quorum sensing in plant growth-promoting rhizobacteria. Plant Biotechnol J (2008) 0.92

The Pseudomonas aeruginosa global regulator MvaT specifically binds to the ptxS upstream region and enhances ptxS expression. Microbiology (2004) 0.92

Bacteria clustering by polymers induces the expression of quorum-sensing-controlled phenotypes. Nat Chem (2013) 0.91

Structural rearrangement in an RsmA/CsrA ortholog of Pseudomonas aeruginosa creates a dimeric RNA-binding protein, RsmN. Structure (2013) 0.91

Targeting Staphylococcus aureus quorum sensing with nonpeptidic small molecule inhibitors. J Med Chem (2014) 0.91

Novel approaches to the treatment of Pseudomonas aeruginosa infections in cystic fibrosis. Eur Respir J (2012) 0.89

Salmonella Typhi sense host neuroendocrine stress hormones and release the toxin haemolysin E. EMBO Rep (2011) 0.89

N-acyl homoserine lactones are degraded via an amidolytic activity in Comamonas sp. strain D1. Arch Microbiol (2006) 0.89

Synthetic polymers for simultaneous bacterial sequestration and quorum sense interference. Angew Chem Int Ed Engl (2011) 0.89

Thermoresponsive polymer colloids for drug delivery and cancer therapy. Macromol Biosci (2011) 0.88

Dioxygenase-mediated quenching of quinolone-dependent quorum sensing in Pseudomonas aeruginosa. Chem Biol (2009) 0.88

In Helicobacter pylori, LuxS is a key enzyme in cysteine provision through a reverse transsulfuration pathway. J Bacteriol (2010) 0.87

LuxS-independent formation of AI-2 from ribulose-5-phosphate. BMC Microbiol (2008) 0.87

Characterisation of two quorum sensing systems in the endophytic Serratia plymuthica strain G3: differential control of motility and biofilm formation according to life-style. BMC Microbiol (2011) 0.86

Side-chain-to-tail thiolactone peptide inhibitors of the staphylococcal quorum-sensing system. Bioorg Med Chem Lett (2003) 0.85

Biofilm development on Caenorhabditis elegans by Yersinia is facilitated by quorum sensing-dependent repression of type III secretion. PLoS Pathog (2011) 0.85

Helicobacter pylori FlhB function: the FlhB C-terminal homologue HP1575 acts as a "spare part" to permit flagellar export when the HP0770 FlhBCC domain is deleted. J Bacteriol (2006) 0.85

The PA4204 gene encodes a periplasmic gluconolactonase (PpgL) which is important for fitness of Pseudomonas aeruginosa. Microbiology (2008) 0.85

Nasal immunization with homogenate and peptide antigens induces protective immunity against Trichinella spiralis. Infect Immun (2002) 0.84

Quorum sensing and the lifestyle of Yersinia. Curr Issues Mol Biol (2006) 0.84

LuxS-based quorum sensing does not affect the ability of Salmonella enterica serovar Typhimurium to express the SPI-1 type 3 secretion system, induce membrane ruffles, or invade epithelial cells. J Bacteriol (2009) 0.83

Escherichia coli gets the message. Nat Med (2003) 0.83

The putative influence of the agr operon upon survival mechanisms used by Clostridium acetobutylicum. Math Biosci (2013) 0.83

Coenzyme A-transferase-independent butyrate re-assimilation in Clostridium acetobutylicum-evidence from a mathematical model. Appl Microbiol Biotechnol (2014) 0.83

Liposome entrapment and immunogenic studies of a synthetic lipophilic multiple antigenic peptide bearing VP1 and VP3 domains of the hepatitis A virus: a robust method for vaccine design. FEBS Lett (2003) 0.83

Homochiral 4-azalysine building blocks: syntheses and applications in solid-phase chemistry. J Org Chem (2002) 0.82

The Pseudomonas aeruginosa quinolone quorum sensing signal alters the multicellular behaviour of Pseudomonas putida KT2440. Res Microbiol (2011) 0.82

End-stapled homo and hetero collagen triple helices: a click chemistry approach. Chem Commun (Camb) (2010) 0.81

Interference with the germination and growth of Ulva zoospores by quorum-sensing molecules from Ulva-associated epiphytic bacteria. Environ Microbiol (2013) 0.81