Cis1/Atg31 is required for autophagosome formation in Saccharomyces cerevisiae.

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Nutrient-dependent mTORC1 association with the ULK1-Atg13-FIP200 complex required for autophagy. Mol Biol Cell (2009) 9.14

Beclin 1 forms two distinct phosphatidylinositol 3-kinase complexes with mammalian Atg14 and UVRAG. Mol Biol Cell (2008) 7.32

FIP200, a ULK-interacting protein, is required for autophagosome formation in mammalian cells. J Cell Biol (2008) 7.16

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Kinase-inactivated ULK proteins inhibit autophagy via their conserved C-terminal domains using an Atg13-independent mechanism. Mol Cell Biol (2008) 4.47

The machinery of macroautophagy. Cell Res (2013) 3.13

Tor directly controls the Atg1 kinase complex to regulate autophagy. Mol Cell Biol (2009) 2.86

Mitophagy in yeast occurs through a selective mechanism. J Biol Chem (2008) 2.80

Organization of the pre-autophagosomal structure responsible for autophagosome formation. Mol Biol Cell (2008) 2.49

Architecture of the Atg17 complex as a scaffold for autophagosome biogenesis. Cell (2012) 2.30

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Genome-wide functional analysis reveals that infection-associated fungal autophagy is necessary for rice blast disease. Proc Natl Acad Sci U S A (2009) 1.53

In vivo reconstitution of autophagy in Saccharomyces cerevisiae. J Cell Biol (2008) 1.48

Bif-1/endophilin B1: a candidate for crescent driving force in autophagy. Cell Death Differ (2009) 1.46

Piecemeal microautophagy of the nucleus requires the core macroautophagy genes. Mol Biol Cell (2008) 1.45

Increased levels of reduced cytochrome b and mitophagy components are required to trigger nonspecific autophagy following induced mitochondrial dysfunction. J Cell Sci (2012) 1.45

Autophagy in neurodegeneration and development. Biochim Biophys Acta (2008) 1.38

Autophagy-physiology and pathophysiology. Histochem Cell Biol (2008) 1.31

Molecular mechanism and physiological role of pexophagy. FEBS Lett (2010) 1.31

Crohn disease: a current perspective on genetics, autophagy and immunity. Autophagy (2011) 1.26

Peroxisome size provides insights into the function of autophagy-related proteins. Mol Biol Cell (2009) 1.21

The incredible ULKs. Cell Commun Signal (2012) 1.12

Autophagy as an important process in gut homeostasis and Crohn's disease pathogenesis. Gut (2008) 1.10

Atg29 phosphorylation regulates coordination of the Atg17-Atg31-Atg29 complex with the Atg11 scaffold during autophagy initiation. Proc Natl Acad Sci U S A (2013) 1.10

Mitochondria autophagy in yeast. Antioxid Redox Signal (2011) 1.10

Drosophila as a model system to study autophagy. Semin Immunopathol (2010) 0.99

ATG13: just a companion, or an executor of the autophagic program? Autophagy (2014) 0.87

Atg1 family kinases in autophagy initiation. Cell Mol Life Sci (2015) 0.87

Atg35, a micropexophagy-specific protein that regulates micropexophagic apparatus formation in Pichia pastoris. Autophagy (2011) 0.86

A multiple ATG gene knockout strain for yeast two-hybrid analysis. Autophagy (2009) 0.86

Autophagy signal transduction by ATG proteins: from hierarchies to networks. Cell Mol Life Sci (2015) 0.83

New insights into autophagy using a multiple knockout strain. Autophagy (2008) 0.82

The Cytoplasm-to-Vacuole Targeting Pathway: A Historical Perspective. Int J Cell Biol (2012) 0.81

Intergenic transcriptional interference is blocked by RNA polymerase III transcription factor TFIIIB in Saccharomyces cerevisiae. Genetics (2013) 0.80

Regulation of protein homeostasis in neurodegenerative diseases: the role of coding and non-coding genes. Cell Mol Life Sci (2015) 0.77

Phosphorylation of Atg31 is required for autophagy. Protein Cell (2015) 0.76

Autophagy: New Questions from Recent Answers. ISRN Mol Biol (2012) 0.75

The role of autophagy during the early neonatal starvation period. Nature (2004) 22.40

Guidelines for the use and interpretation of assays for monitoring autophagy. Autophagy (2012) 20.08

Impairment of starvation-induced and constitutive autophagy in Atg7-deficient mice. J Cell Biol (2005) 18.60

In vivo analysis of autophagy in response to nutrient starvation using transgenic mice expressing a fluorescent autophagosome marker. Mol Biol Cell (2003) 17.55

Promotion of tumorigenesis by heterozygous disruption of the beclin 1 autophagy gene. J Clin Invest (2003) 16.67

Dynamics and diversity in autophagy mechanisms: lessons from yeast. Nat Rev Mol Cell Biol (2009) 9.32

LC3, GABARAP and GATE16 localize to autophagosomal membrane depending on form-II formation. J Cell Sci (2004) 9.20

A unified nomenclature for yeast autophagy-related genes. Dev Cell (2003) 9.18

The role of Atg proteins in autophagosome formation. Annu Rev Cell Dev Biol (2011) 8.18

Atg8, a ubiquitin-like protein required for autophagosome formation, mediates membrane tethering and hemifusion. Cell (2007) 7.11

Mouse Apg16L, a novel WD-repeat protein, targets to the autophagic isolation membrane with the Apg12-Apg5 conjugate. J Cell Sci (2003) 6.50

The Atg12-Atg5 conjugate has a novel E3-like activity for protein lipidation in autophagy. J Biol Chem (2007) 6.28

Hierarchy of Atg proteins in pre-autophagosomal structure organization. Genes Cells (2007) 6.14

Mitochondria-anchored receptor Atg32 mediates degradation of mitochondria via selective autophagy. Dev Cell (2009) 5.85

Autophagosome formation in mammalian cells. Cell Struct Funct (2002) 5.58

Formation of the approximately 350-kDa Apg12-Apg5.Apg16 multimeric complex, mediated by Apg16 oligomerization, is essential for autophagy in yeast. J Biol Chem (2002) 4.27

Atg17 functions in cooperation with Atg1 and Atg13 in yeast autophagy. Mol Biol Cell (2005) 4.02

Molecular machinery of autophagosome formation in yeast, Saccharomyces cerevisiae. FEBS Lett (2007) 3.65

Leaf senescence and starvation-induced chlorosis are accelerated by the disruption of an Arabidopsis autophagy gene. Plant Physiol (2002) 3.47

Structural basis of target recognition by Atg8/LC3 during selective autophagy. Genes Cells (2008) 3.23

Processing of ATG8s, ubiquitin-like proteins, and their deconjugation by ATG4s are essential for plant autophagy. Plant Cell (2004) 3.17

Tor directly controls the Atg1 kinase complex to regulate autophagy. Mol Cell Biol (2009) 2.86

Atg8-family interacting motif crucial for selective autophagy. FEBS Lett (2010) 2.83

Drosophila argonaute1 and argonaute2 employ distinct mechanisms for translational repression. Mol Cell (2009) 2.69

Yeast autophagosomes: de novo formation of a membrane structure. Trends Cell Biol (2002) 2.69

Autophagy is required for maintenance of amino acid levels and protein synthesis under nitrogen starvation. J Biol Chem (2005) 2.64

Assortment of phosphatidylinositol 3-kinase complexes--Atg14p directs association of complex I to the pre-autophagosomal structure in Saccharomyces cerevisiae. Mol Biol Cell (2006) 2.63

Organization of the pre-autophagosomal structure responsible for autophagosome formation. Mol Biol Cell (2008) 2.49

Tor2 directly phosphorylates the AGC kinase Ypk2 to regulate actin polarization. Mol Cell Biol (2005) 2.44

Autophagy negatively regulates cell death by controlling NPR1-dependent salicylic acid signaling during senescence and the innate immune response in Arabidopsis. Plant Cell (2009) 2.32

The structure of Atg4B-LC3 complex reveals the mechanism of LC3 processing and delipidation during autophagy. EMBO J (2009) 2.25

In vivo and in vitro reconstitution of Atg8 conjugation essential for autophagy. J Biol Chem (2004) 2.21

Structure of Atg5.Atg16, a complex essential for autophagy. J Biol Chem (2006) 2.18

Atg9 vesicles are an important membrane source during early steps of autophagosome formation. J Cell Biol (2012) 2.12

AtATG genes, homologs of yeast autophagy genes, are involved in constitutive autophagy in Arabidopsis root tip cells. Plant Cell Physiol (2006) 2.06

ATP-dependent human RISC assembly pathways. Nat Struct Mol Biol (2009) 2.04

The crystal structure of microtubule-associated protein light chain 3, a mammalian homologue of Saccharomyces cerevisiae Atg8. Genes Cells (2004) 1.98

Autophagy in development and stress responses of plants. Autophagy (2006) 1.93

Mobilization of rubisco and stroma-localized fluorescent proteins of chloroplasts to the vacuole by an ATG gene-dependent autophagic process. Plant Physiol (2008) 1.91

The Atg18-Atg2 complex is recruited to autophagic membranes via phosphatidylinositol 3-phosphate and exerts an essential function. J Biol Chem (2008) 1.89

The early secretory pathway contributes to autophagy in yeast. Cell Struct Funct (2003) 1.83

Transport of phosphatidylinositol 3-phosphate into the vacuole via autophagic membranes in Saccharomyces cerevisiae. Genes Cells (2008) 1.74

Organelle degradation during the lens and erythroid differentiation is independent of autophagy. Biochem Biophys Res Commun (2005) 1.73

Autophagy plays a role in chloroplast degradation during senescence in individually darkened leaves. Plant Physiol (2008) 1.72

Current knowledge of the pre-autophagosomal structure (PAS). FEBS Lett (2010) 1.72

Two newly identified sites in the ubiquitin-like protein Atg8 are essential for autophagy. EMBO Rep (2006) 1.72

Structural basis for the specificity and catalysis of human Atg4B responsible for mammalian autophagy. J Biol Chem (2005) 1.70

Studies of cargo delivery to the vacuole mediated by autophagosomes in Saccharomyces cerevisiae. Dev Cell (2002) 1.68

The crystal structure of plant ATG12 and its biological implication in autophagy. Autophagy (2005) 1.63

Starvation triggers the delivery of the endoplasmic reticulum to the vacuole via autophagy in yeast. Traffic (2005) 1.62

Recognition of the pre-miRNA structure by Drosophila Dicer-1. Nat Struct Mol Biol (2011) 1.61

Ald6p is a preferred target for autophagy in yeast, Saccharomyces cerevisiae. J Biol Chem (2004) 1.60

SKD1 AAA ATPase-dependent endosomal transport is involved in autolysosome formation. Cell Struct Funct (2002) 1.58

The crystal structure of Atg3, an autophagy-related ubiquitin carrier protein (E2) enzyme that mediates Atg8 lipidation. J Biol Chem (2007) 1.55

Characterization of a novel autophagy-specific gene, ATG29. Biochem Biophys Res Commun (2005) 1.54

Atg4 recycles inappropriately lipidated Atg8 to promote autophagosome biogenesis. Autophagy (2012) 1.52

Starvation induced cell death in autophagy-defective yeast mutants is caused by mitochondria dysfunction. PLoS One (2011) 1.51

Atg17 recruits Atg9 to organize the pre-autophagosomal structure. Genes Cells (2009) 1.50

PI3K signaling of autophagy is required for starvation tolerance and virulenceof Cryptococcus neoformans. J Clin Invest (2008) 1.45

An Arabidopsis homolog of yeast ATG6/VPS30 is essential for pollen germination. Plant Physiol (2007) 1.44

Characterization of the Atg17-Atg29-Atg31 complex specifically required for starvation-induced autophagy in Saccharomyces cerevisiae. Biochem Biophys Res Commun (2009) 1.44

In vitro reconstitution of plant Atg8 and Atg12 conjugation systems essential for autophagy. J Biol Chem (2007) 1.43

Fine mapping of autophagy-related proteins during autophagosome formation in Saccharomyces cerevisiae. J Cell Sci (2013) 1.42

Structural basis of Atg8 activation by a homodimeric E1, Atg7. Mol Cell (2011) 1.38

Selective transport of alpha-mannosidase by autophagic pathways: identification of a novel receptor, Atg34p. J Biol Chem (2010) 1.34

Structure-function relationship of Atg12, a ubiquitin-like modifier essential for autophagy. Autophagy (2005) 1.32

Interrelationships among Atg proteins during autophagy in Saccharomyces cerevisiae. Yeast (2004) 1.28

A sorting nexin PpAtg24 regulates vacuolar membrane dynamics during pexophagy via binding to phosphatidylinositol-3-phosphate. Mol Biol Cell (2004) 1.26

The first molecular evidence that autophagy relates rimmed vacuole formation in chloroquine myopathy. J Biochem (2002) 1.24

Mouse Apg10 as an Apg12-conjugating enzyme: analysis by the conjugation-mediated yeast two-hybrid method. FEBS Lett (2002) 1.22

Modification of a ubiquitin-like protein Paz2 conducted micropexophagy through formation of a novel membrane structure. Mol Biol Cell (2003) 1.20

Autophagy-related protein 8 (Atg8) family interacting motif in Atg3 mediates the Atg3-Atg8 interaction and is crucial for the cytoplasm-to-vacuole targeting pathway. J Biol Chem (2010) 1.20

Highly oxidized peroxisomes are selectively degraded via autophagy in Arabidopsis. Plant Cell (2013) 1.18

Dimeric coiled-coil structure of Saccharomyces cerevisiae Atg16 and its functional significance in autophagy. J Biol Chem (2009) 1.17

Role of the Apg12 conjugation system in mammalian autophagy. Int J Biochem Cell Biol (2003) 1.15

Structure-based analyses reveal distinct binding sites for Atg2 and phosphoinositides in Atg18. J Biol Chem (2012) 1.13

PtdIns 3-Kinase Orchestrates Autophagosome Formation in Yeast. J Lipids (2011) 1.11

Atg12-Atg5 conjugate enhances E2 activity of Atg3 by rearranging its catalytic site. Nat Struct Mol Biol (2013) 1.11

Lap3 is a selective target of autophagy in yeast, Saccharomyces cerevisiae. Biochem Biophys Res Commun (2008) 1.10

ATG systems from the protein structural point of view. Chem Rev (2009) 1.09

Autophagy-related protein 32 acts as autophagic degron and directly initiates mitophagy. J Biol Chem (2012) 1.09

Structure of the Atg12-Atg5 conjugate reveals a platform for stimulating Atg8-PE conjugation. EMBO Rep (2012) 1.07

Atg9 vesicles recruit vesicle-tethering proteins Trs85 and Ypt1 to the autophagosome formation site. J Biol Chem (2012) 1.07

The yeast Tor signaling pathway is involved in G2/M transition via polo-kinase. PLoS One (2008) 1.06

Atg14: a key player in orchestrating autophagy. Int J Cell Biol (2011) 1.05

Atg38 is required for autophagy-specific phosphatidylinositol 3-kinase complex integrity. J Cell Biol (2013) 1.04

A family of basic amino acid transporters of the vacuolar membrane from Saccharomyces cerevisiae. J Biol Chem (2004) 1.02

Organ-specific quality control of plant peroxisomes is mediated by autophagy. J Cell Sci (2014) 1.01

Selective transport of alpha-mannosidase by autophagic pathways: structural basis for cargo recognition by Atg19 and Atg34. J Biol Chem (2010) 1.01

Structure of the novel C-terminal domain of vacuolar protein sorting 30/autophagy-related protein 6 and its specific role in autophagy. J Biol Chem (2012) 1.00