Published in Proteomics on April 01, 2007
c-Myc suppression of miR-23a/b enhances mitochondrial glutaminase expression and glutamine metabolism. Nature (2009) 13.28
The identification of disease-induced biomarkers in the urine of BSE infected cattle. Proteome Sci (2008) 0.85
Application of mass spectrometry-based proteomics for biomarker discovery in neurological disorders. Ann Indian Acad Neurol (2009) 0.82
Finding biomarkers is getting easier. Ecotoxicology (2012) 0.77
c-Myc-regulated microRNAs modulate E2F1 expression. Nature (2005) 31.81
Development of human protein reference database as an initial platform for approaching systems biology in humans. Genome Res (2003) 14.79
c-Myc suppression of miR-23a/b enhances mitochondrial glutaminase expression and glutamine metabolism. Nature (2009) 13.28
HIF-1-mediated expression of pyruvate dehydrogenase kinase: a metabolic switch required for cellular adaptation to hypoxia. Cell Metab (2006) 13.22
Tackling the widespread and critical impact of batch effects in high-throughput data. Nat Rev Genet (2010) 11.82
Widespread microRNA repression by Myc contributes to tumorigenesis. Nat Genet (2007) 10.78
Otto Warburg's contributions to current concepts of cancer metabolism. Nat Rev Cancer (2011) 9.68
Direct evidence that sulfhydryl groups of Keap1 are the sensors regulating induction of phase 2 enzymes that protect against carcinogens and oxidants. Proc Natl Acad Sci U S A (2002) 8.01
Pyruvate kinase M2 is a PHD3-stimulated coactivator for hypoxia-inducible factor 1. Cell (2011) 7.33
Cancer's molecular sweet tooth and the Warburg effect. Cancer Res (2006) 7.24
HIF-1 regulates cytochrome oxidase subunits to optimize efficiency of respiration in hypoxic cells. Cell (2007) 6.31
HIF-1 inhibits mitochondrial biogenesis and cellular respiration in VHL-deficient renal cell carcinoma by repression of C-MYC activity. Cancer Cell (2007) 6.06
Control of T(H)17/T(reg) balance by hypoxia-inducible factor 1. Cell (2011) 5.63
Global mapping of c-Myc binding sites and target gene networks in human B cells. Proc Natl Acad Sci U S A (2006) 5.27
Targeting mitochondrial glutaminase activity inhibits oncogenic transformation. Cancer Cell (2010) 5.02
Myc stimulates nuclearly encoded mitochondrial genes and mitochondrial biogenesis. Mol Cell Biol (2005) 4.99
Inhibition of lactate dehydrogenase A induces oxidative stress and inhibits tumor progression. Proc Natl Acad Sci U S A (2010) 4.97
HIF-dependent antitumorigenic effect of antioxidants in vivo. Cancer Cell (2007) 4.81
Glucose-independent glutamine metabolism via TCA cycling for proliferation and survival in B cells. Cell Metab (2012) 4.80
Digoxin and other cardiac glycosides inhibit HIF-1alpha synthesis and block tumor growth. Proc Natl Acad Sci U S A (2008) 4.79
An integrated database of genes responsive to the Myc oncogenic transcription factor: identification of direct genomic targets. Genome Biol (2003) 4.49
Human-induced pluripotent stem cells from blood cells of healthy donors and patients with acquired blood disorders. Blood (2009) 4.22
Candidate exome capture identifies mutation of SDCCAG8 as the cause of a retinal-renal ciliopathy. Nat Genet (2010) 3.99
Lin-28B transactivation is necessary for Myc-mediated let-7 repression and proliferation. Proc Natl Acad Sci U S A (2009) 3.76
Hypoxia-inducible factor 1 and dysregulated c-Myc cooperatively induce vascular endothelial growth factor and metabolic switches hexokinase 2 and pyruvate dehydrogenase kinase 1. Mol Cell Biol (2007) 3.51
Classifying gene expression profiles from pairwise mRNA comparisons. Stat Appl Genet Mol Biol (2004) 3.45
Inhibition of glutaminase preferentially slows growth of glioma cells with mutant IDH1. Cancer Res (2010) 3.30
Simple decision rules for classifying human cancers from gene expression profiles. Bioinformatics (2005) 3.24
RACK1 competes with HSP90 for binding to HIF-1alpha and is required for O(2)-independent and HSP90 inhibitor-induced degradation of HIF-1alpha. Mol Cell (2007) 3.09
Evidence of structural remodeling in the dyssynchronous failing heart. Circ Res (2005) 3.05
Multifaceted roles of glycolytic enzymes. Trends Biochem Sci (2005) 3.01
Mapping sites of O-GlcNAc modification using affinity tags for serine and threonine post-translational modifications. Mol Cell Proteomics (2002) 2.88
An integrated model of cardiac mitochondrial energy metabolism and calcium dynamics. Biophys J (2003) 2.52
Measuring and mapping cardiac fiber and laminar architecture using diffusion tensor MR imaging. Ann N Y Acad Sci (2005) 2.35
Evaluation of myc E-box phylogenetic footprints in glycolytic genes by chromatin immunoprecipitation assays. Mol Cell Biol (2004) 2.19
Global regulation of nucleotide biosynthetic genes by c-Myc. PLoS One (2008) 2.12
Large deformation diffeomorphic metric mapping of vector fields. IEEE Trans Med Imaging (2005) 2.09
From mitochondrial ion channels to arrhythmias in the heart: computational techniques to bridge the spatio-temporal scales. Philos Trans A Math Phys Eng Sci (2008) 2.05
Reprogramming of proline and glutamine metabolism contributes to the proliferative and metabolic responses regulated by oncogenic transcription factor c-MYC. Proc Natl Acad Sci U S A (2012) 2.02
Activation of transferrin receptor 1 by c-Myc enhances cellular proliferation and tumorigenesis. Mol Cell Biol (2006) 2.01
A mitochondrial oscillator dependent on reactive oxygen species. Biophys J (2004) 1.99
An integrative model of the cardiac ventricular myocyte incorporating local control of Ca2+ release. Biophys J (2002) 1.97
Robust prostate cancer marker genes emerge from direct integration of inter-study microarray data. Bioinformatics (2005) 1.91
A computational model of the human left-ventricular epicardial myocyte. Biophys J (2004) 1.88
The role of stochastic and modal gating of cardiac L-type Ca2+ channels on early after-depolarizations. Biophys J (2004) 1.78
Large-scale integration of cancer microarray data identifies a robust common cancer signature. BMC Bioinformatics (2007) 1.74
A computational model integrating electrophysiology, contraction, and mitochondrial bioenergetics in the ventricular myocyte. Biophys J (2006) 1.69
Ex vivo 3D diffusion tensor imaging and quantification of cardiac laminar structure. Magn Reson Med (2005) 1.68
Targeted inhibition of tumor-specific glutaminase diminishes cell-autonomous tumorigenesis. J Clin Invest (2015) 1.67
c-myc overexpression causes anaplasia in medulloblastoma. Cancer Res (2006) 1.66
MYC overexpression induces prostatic intraepithelial neoplasia and loss of Nkx3.1 in mouse luminal epithelial cells. PLoS One (2010) 1.65
Myosin binding protein C is differentially phosphorylated upon myocardial stunning in canine and rat hearts-- evidence for novel phosphorylation sites. Proteomics (2006) 1.65
Histopathological and molecular prognostic markers in medulloblastoma: c-myc, N-myc, TrkC, and anaplasia. J Neuropathol Exp Neurol (2004) 1.62
A strategy for identifying transcription factor binding sites reveals two classes of genomic c-Myc target sites. Proc Natl Acad Sci U S A (2003) 1.56
Transcriptomic profiling of the canine tachycardia-induced heart failure model: global comparison to human and murine heart failure. J Mol Cell Cardiol (2005) 1.54
MYC and Prostate Cancer. Genes Cancer (2010) 1.54
Cell-type independent MYC target genes reveal a primordial signature involved in biomass accumulation. PLoS One (2011) 1.53
Transport of Relational Structures in Groups of Diffeomorphisms. J Math Imaging Vis (2008) 1.51
Role of NADPH oxidase in arsenic-induced reactive oxygen species formation and cytotoxicity in myeloid leukemia cells. Proc Natl Acad Sci U S A (2004) 1.49
The c-Myc target gene PRDX3 is required for mitochondrial homeostasis and neoplastic transformation. Proc Natl Acad Sci U S A (2002) 1.49
Merging microarray data from separate breast cancer studies provides a robust prognostic test. BMC Bioinformatics (2008) 1.48
Expanding the subproteome of the inner mitochondria using protein separation technologies: one- and two-dimensional liquid chromatography and two-dimensional gel electrophoresis. Mol Cell Proteomics (2006) 1.48
Mutant huntingtin N-terminal fragments of specific size mediate aggregation and toxicity in neuronal cells. J Biol Chem (2009) 1.47
A reaction-diffusion model of ROS-induced ROS release in a mitochondrial network. PLoS Comput Biol (2010) 1.47
Blocking lactate export by inhibiting the Myc target MCT1 Disables glycolysis and glutathione synthesis. Cancer Res (2013) 1.46
Biology and treatment of Burkitt's lymphoma. Curr Opin Hematol (2007) 1.45
Mechanisms of excitation-contraction coupling in an integrative model of the cardiac ventricular myocyte. Biophys J (2005) 1.42
The opportunistic pathogen Toxoplasma gondii deploys a diverse legion of invasion and survival proteins. J Biol Chem (2005) 1.40
Identification and quantification of S-nitrosylation by cysteine reactive tandem mass tag switch assay. Mol Cell Proteomics (2011) 1.40
Autocitrullination of human peptidyl arginine deiminase type 4 regulates protein citrullination during cell activation. Arthritis Rheum (2010) 1.39
Identifying tightly regulated and variably expressed networks by Differential Rank Conservation (DIRAC). PLoS Comput Biol (2010) 1.38
Calcineurin promotes hypoxia-inducible factor 1alpha expression by dephosphorylating RACK1 and blocking RACK1 dimerization. J Biol Chem (2007) 1.38
Electrophilic tuning of the chemoprotective natural product sulforaphane. Proc Natl Acad Sci U S A (2010) 1.37
Role of sodium-calcium exchanger in modulating the action potential of ventricular myocytes from normal and failing hearts. Circ Res (2003) 1.35
A comprehensive map of the human urinary proteome. J Proteome Res (2011) 1.34
A quantitative proteomic approach for identification of potential biomarkers in hepatocellular carcinoma. J Proteome Res (2008) 1.27
Design, synthesis, and pharmacological evaluation of bis-2-(5-phenylacetamido-1,2,4-thiadiazol-2-yl)ethyl sulfide 3 (BPTES) analogs as glutaminase inhibitors. J Med Chem (2012) 1.27
MYC, microRNAs and glutamine addiction in cancers. Cell Cycle (2009) 1.26
Induction of ectopic Myc target gene JAG2 augments hypoxic growth and tumorigenesis in a human B-cell model. Proc Natl Acad Sci U S A (2010) 1.25
Computational medicine: translating models to clinical care. Sci Transl Med (2012) 1.25
Effects of hypoxia on tumor metabolism. Cancer Metastasis Rev (2007) 1.25
Computational cardiac anatomy using MRI. Magn Reson Med (2004) 1.23
Diffeomorphic Matching of Diffusion Tensor Images. Proc IEEE Comput Soc Conf Comput Vis Pattern Recognit (2006) 1.23
Gene expression profiles in end-stage human idiopathic dilated cardiomyopathy: altered expression of apoptotic and cytoskeletal genes. Genomics (2004) 1.22
Barrier-to-autointegration factor proteome reveals chromatin-regulatory partners. PLoS One (2009) 1.21
Control and regulation of mitochondrial energetics in an integrated model of cardiomyocyte function. Biophys J (2009) 1.20
Glyceraldehyde-3-phosphate dehydrogenase (GAPDH) is pyruvylated during 3-bromopyruvate mediated cancer cell death. Anticancer Res (2009) 1.19
Conditional deletion of c-myc does not impair liver regeneration. Cancer Res (2006) 1.19
Relative expression analysis for molecular cancer diagnosis and prognosis. Technol Cancer Res Treat (2010) 1.19
A nontranscriptional role for HIF-1α as a direct inhibitor of DNA replication. Sci Signal (2013) 1.17
iTRAQ analysis of complex proteome alterations in 3xTgAD Alzheimer's mice: understanding the interface between physiology and disease. PLoS One (2008) 1.16