Published in J Clin Invest on February 01, 1992
Protein measurement with the Folin phenol reagent. J Biol Chem (1951) 1743.91
Cleavage of structural proteins during the assembly of the head of bacteriophage T4. Nature (1970) 1528.65
DNA sequencing with chain-terminating inhibitors. Proc Natl Acad Sci U S A (1977) 790.54
Primer-directed enzymatic amplification of DNA with a thermostable DNA polymerase. Science (1988) 220.77
Specific synthesis of DNA in vitro via a polymerase-catalyzed chain reaction. Methods Enzymol (1987) 58.68
Number and evolutionary conservation of alpha- and beta-tubulin and cytoplasmic beta- and gamma-actin genes using specific cloned cDNA probes. Cell (1980) 17.55
Human lipoprotein lipase complementary DNA sequence. Science (1987) 9.50
Unstable beta-globin mRNA in mRNA-deficient beta o thalassemia. Cell (1981) 3.80
Lipolytic enzymes and plasma lipoprotein metabolism. Annu Rev Biochem (1980) 2.32
Detection and characterization of the heterozygote state for lipoprotein lipase deficiency. Arteriosclerosis (1989) 2.14
mRNA-deficient beta o-thalassemia results from a single nucleotide deletion. Nucleic Acids Res (1982) 1.78
Structure of the human lipoprotein lipase gene. Biochemistry (1989) 1.72
Missense mutation (Gly----Glu188) of human lipoprotein lipase imparting functional deficiency. J Biol Chem (1990) 1.57
A major insertion accounts for a significant proportion of mutations underlying human lipoprotein lipase deficiency. Proc Natl Acad Sci U S A (1989) 1.41
Tissue lipoprotein lipase activity and its action in lipoprotein metabolism. Int J Biochem (1981) 1.41
Organization of the human lipoprotein lipase gene and evolution of the lipase gene family. Proc Natl Acad Sci U S A (1989) 1.38
Molecular heterogeneity of variant isovaleryl-CoA dehydrogenase from cultured isovaleric acidemia fibroblasts. Proc Natl Acad Sci U S A (1985) 1.34
A missense mutation at codon 188 of the human lipoprotein lipase gene is a frequent cause of lipoprotein lipase deficiency in persons of different ancestries. J Clin Invest (1990) 1.32
Partial gene duplication involving exon-Alu interchange results in lipoprotein lipase deficiency. Am J Hum Genet (1990) 1.31
Lipoprotein lipase secretion by human monocyte-derived macrophages. J Clin Invest (1982) 1.26
Familial type I hyperlipoproteinemia caused by apolipoprotein C-II deficiency. Atherosclerosis (1979) 1.09
Structure and polymorphic map of human lipoprotein lipase gene. Biochim Biophys Acta (1990) 1.06
Amino acid substitution (Ile194----Thr) in exon 5 of the lipoprotein lipase gene causes lipoprotein lipase deficiency in three unrelated probands. Support for a multicentric origin. J Clin Invest (1991) 1.01
Lipoprotein lipaseBethesda: a single amino acid substitution (Ala-176----Thr) leads to abnormal heparin binding and loss of enzymic activity. Proc Natl Acad Sci U S A (1990) 0.99
Lipoprotein lipase deficiency resulting from a nonsense mutation in exon 3 of the lipoprotein lipase gene. Am J Hum Genet (1990) 0.97
Biosynthesis of electron transfer flavoprotein in a cell-free system and in cultured human fibroblasts. Defect in the alpha subunit synthesis is a primary lesion in glutaric aciduria type II. J Clin Invest (1986) 0.95
Purification and characterization of lipoprotein lipase and hepatic triglyceride lipase from human postheparin plasma: production of monospecific antibody to the individual lipase. Biochim Biophys Acta (1989) 0.92
Familial chylomicronemia (type I hyperlipoproteinemia) due to a single missense mutation in the lipoprotein lipase gene. J Clin Invest (1991) 0.90
Frameshift mutation in exon 3 of the lipoprotein lipase gene causes a premature stop codon and lipoprotein lipase deficiency. Mol Biol Med (1990) 0.89
Compound heterozygote for lipoprotein lipase deficiency: Ser----Thr244 and transition in 3' splice site of intron 2 (AG----AA) in the lipoprotein lipase gene. Am J Hum Genet (1990) 0.89
Identification of two separate allelic mutations in the lipoprotein lipase gene of a patient with the familial hyperchylomicronemia syndrome. J Biol Chem (1991) 0.88
Purification and characterization of human lipoprotein lipase and hepatic triglyceride lipase. Reactivity with monoclonal antibodies to hepatic triglyceride lipase. J Biol Chem (1985) 0.88
A sandwich-enzyme immunoassay for the quantification of lipoprotein lipase and hepatic triglyceride lipase in human postheparin plasma using monoclonal antibodies to the corresponding enzymes. J Lipid Res (1990) 0.80
DNA sequence of lipoprotein lipase cDNA cloned from human monocytic leukemia THP-1 cells. Nucleic Acids Res (1990) 0.78
LC3, a mammalian homologue of yeast Apg8p, is localized in autophagosome membranes after processing. EMBO J (2000) 41.48
XBP1 mRNA is induced by ATF6 and spliced by IRE1 in response to ER stress to produce a highly active transcription factor. Cell (2001) 18.68
Dissection of autophagosome formation using Apg5-deficient mouse embryonic stem cells. J Cell Biol (2001) 13.98
Two dimensional then layer chromatographic separation of polar lipids and determination of phospholipids by phosphorus analysis of spots. Lipids (1970) 11.81
Bafilomycin A1, a specific inhibitor of vacuolar-type H(+)-ATPase, inhibits acidification and protein degradation in lysosomes of cultured cells. J Biol Chem (1991) 7.04
Primary LAMP-2 deficiency causes X-linked vacuolar cardiomyopathy and myopathy (Danon disease). Nature (2000) 5.71
A cell-specific nuclear receptor is essential for adrenal and gonadal development and sexual differentiation. Cell (1994) 4.55
The mouse SKD1, a homologue of yeast Vps4p, is required for normal endosomal trafficking and morphology in mammalian cells. Mol Biol Cell (2000) 4.22
Characterization of Rose Bengal binding to sinusoidal and bile canalicular plasma membrane from rat liver. Biochim Biophys Acta (1989) 3.47
Tbx5 associates with Nkx2-5 and synergistically promotes cardiomyocyte differentiation. Nat Genet (2001) 3.14
A defect in the Kv channel-interacting protein 2 (KChIP2) gene leads to a complete loss of I(to) and confers susceptibility to ventricular tachycardia. Cell (2001) 3.13
The gene mutated in ataxia-ocular apraxia 1 encodes the new HIT/Zn-finger protein aprataxin. Nat Genet (2001) 3.01
Heterothallic Behavior of a Homothallic Strain in Saccharomyces Yeast. Genetics (1958) 2.81
Characterization of rec7, an early meiotic recombination gene in Schizosaccharomyces pombe. Genetics (2001) 2.74
Mutanolysin, bacteriolytic agent for cariogenic Streptococci: partial purification and properties. Antimicrob Agents Chemother (1974) 2.68
Involvement of receptor activator of nuclear factor kappaB ligand/osteoclast differentiation factor in osteoclastogenesis from synoviocytes in rheumatoid arthritis. Arthritis Rheum (2000) 2.61
Protein disulfide-isomerase in rat exocrine pancreatic cells is exported from the endoplasmic reticulum despite possessing the retention signal. J Biol Chem (1990) 2.44
PAI-1 deficiency attenuates the fibrogenic response to ureteral obstruction. Kidney Int (2001) 2.41
A mouse homolog of the Escherichia coli recA and Saccharomyces cerevisiae RAD51 genes. Proc Natl Acad Sci U S A (1993) 2.38
Therapeutic effects of ML-236B in primary hypercholesterolemia. Atherosclerosis (1980) 2.35
Longitudinal study of cerebrospinal fluid levels of tau, A beta1-40, and A beta1-42(43) in Alzheimer's disease: a study in Japan. Ann Neurol (1998) 2.25
Weight loss associated with an endotoxin-induced mediator from peritoneal macrophages: the role of cachectin (tumor necrosis factor). Immunol Lett (1985) 2.23
Template engineering of Co-doped BaFe2As2 single-crystal thin films. Nat Mater (2010) 2.22
Hrs, a tyrosine kinase substrate with a conserved double zinc finger domain, is localized to the cytoplasmic surface of early endosomes. J Biol Chem (1997) 2.20
In vitro and in vivo antibacterial activities of T-3761, a new quinolone derivative. Antimicrob Agents Chemother (1993) 2.18
Lipopolysaccharide-treated RAW 264.7 cells produce a mediator that inhibits lipoprotein lipase in 3T3-L1 cells. J Immunol (1985) 2.15
Large-scale screening of intracellular protein localization in living fission yeast cells by the use of a GFP-fusion genomic DNA library. Genes Cells (2000) 2.12
Mice with disrupted GM2/GD2 synthase gene lack complex gangliosides but exhibit only subtle defects in their nervous system. Proc Natl Acad Sci U S A (1996) 2.10
Body fat mass and lean mass as predictors of survival in hemodialysis patients. Kidney Int (2006) 2.04
Reciprocal role of ERK and NF-kappaB pathways in survival and activation of osteoclasts. J Cell Biol (2000) 2.04
Homeostasis model assessment as a clinical index of insulin resistance in type 2 diabetic patients treated with sulfonylureas. Diabetes Care (1999) 2.01
Clarithromycin suppresses bronchial hyperresponsiveness associated with eosinophilic inflammation in patients with asthma. Ann Allergy Asthma Immunol (2000) 1.99
The nuclear receptor steroidogenic factor 1 acts at multiple levels of the reproductive axis. Genes Dev (1994) 1.97
The genetics of alkaline phosphatase formation in Bacillus subtilis. Genetics (1965) 1.96
Malignant eccrine spiradenoma: a case report and review of the literature. Dermatol Surg (2001) 1.94
Separation and properties of five distinct acyl-CoA dehydrogenases from rat liver mitochondria. Identification of a new 2-methyl branched chain acyl-CoA dehydrogenase. J Biol Chem (1983) 1.94
Visualization, direct isolation, and transplantation of midbrain dopaminergic neurons. Proc Natl Acad Sci U S A (2001) 1.93
The mesenchymal factor, FGF10, initiates and maintains the outgrowth of the chick limb bud through interaction with FGF8, an apical ectodermal factor. Development (1997) 1.92
Role of elastic fiber degradation in emphysema-like lesions of pulmonary lymphangiomyomatosis. Hum Pathol (1990) 1.85
Purification and properties of hemagglutinin from culture supernatant of Bacteroides gingivalis. Infect Immun (1986) 1.85
The role of paraxial protocadherin in selective adhesion and cell movements of the mesoderm during Xenopus gastrulation. Development (1998) 1.84
Nuclear receptor steroidogenic factor 1 regulates the müllerian inhibiting substance gene: a link to the sex determination cascade. Cell (1994) 1.83
A new type of hepatitis C virus in patients in Thailand. Biochem Biophys Res Commun (1992) 1.82
Cloning and sequence of the human RecA-like gene cDNA. Nucleic Acids Res (1993) 1.81
Inhibition of RNA phage growth by phenetyl alcohol. Biochem Biophys Res Commun (1964) 1.76
Molecular basis of isovaleric acidemia and medium-chain acyl-CoA dehydrogenase deficiency. Enzyme (1987) 1.76
Evidence for autoregulation of cystathionine gamma-synthase mRNA stability in Arabidopsis. Science (1999) 1.72
Cross-cultural differences in rating hyperactive-disruptive behaviors in children. Am J Psychiatry (1992) 1.71
Vascular endothelial growth factor-C (VEGF-C) expression in human colorectal cancer tissues. Br J Cancer (2000) 1.67
Overexpression of Arabidopsis ESR1 induces initiation of shoot regeneration. Plant Cell (2001) 1.65
Postentry restriction to human immunodeficiency virus-based vector transduction in human monocytes. J Virol (2001) 1.60
Search for supersymmetry using final states with one lepton, jets, and missing transverse momentum with the ATLAS detector in √s=7 TeV pp collisions. Phys Rev Lett (2011) 1.60
Genetic analysis of the developmental processes during germination and outgrowth of Bacillus subtilis spores with temperature-sensitive mutants. Genetics (1969) 1.60
Zebrafish Mesp family genes, mesp-a and mesp-b are segmentally expressed in the presomitic mesoderm, and Mesp-b confers the anterior identity to the developing somites. Development (2000) 1.59
Spot urine uric acid to creatinine ratio used in the estimation of uric acid excretion in primary gout. J Rheumatol (2001) 1.59
Dextran sodium sulfate-induced colitis in germ-free IQI/Jic mice. Exp Anim (2001) 1.58
Splenic macrophages maintain the anti-platelet autoimmune response via uptake of opsonized platelets in patients with immune thrombocytopenic purpura. J Thromb Haemost (2008) 1.58
Chronic administration of ghrelin improves left ventricular dysfunction and attenuates development of cardiac cachexia in rats with heart failure. Circulation (2001) 1.58
Induction of gastric ulcer and intestinal metaplasia in mongolian gerbils infected with Helicobacter pylori. J Gastroenterol (1996) 1.58
Effect of a corticotropin releasing hormone receptor antagonist on colonic sensory and motor function in patients with irritable bowel syndrome. Gut (2004) 1.58
Generalized peritonitis with pneumoperitoneum caused by the spontaneous perforation of pyometra without malignancy: report of a case. Surg Today (1999) 1.56
Purification and characterization of isovaleryl coenzyme A dehydrogenase from rat liver mitochondria. J Biol Chem (1983) 1.56
Reactive oxygen in skeletal muscle. II. Extracellular release of free radicals. J Appl Physiol (1985) (1992) 1.56
Mutational spectrum of the CHAC gene in patients with chorea-acanthocytosis. Eur J Hum Genet (2002) 1.56
Autologous serum eye drops for the treatment of severe dry eye in patients with chronic graft-versus-host disease. Bone Marrow Transplant (2003) 1.55
Establishment of gastric Helicobacter pylori infection in Mongolian gerbils. J Gastroenterol (1996) 1.53
Afferent and efferent connections of the oculomotor region of the fastigial nucleus in the macaque monkey. J Comp Neurol (1990) 1.52
Updated statistical data for malignant melanoma in Japan. Int J Clin Oncol (2001) 1.52
Increased serum nitrate levels in infants with atopic dermatitis. Allergy (2001) 1.51
Clinicopathological features of genetically confirmed Danon disease. Neurology (2002) 1.51
Origin of spontaneous activity in neonatal and adult rat bladders and its enhancement by stretch and muscarinic agonists. Am J Physiol Renal Physiol (2006) 1.50
High shear stress can initiate both platelet aggregation and shedding of procoagulant containing microparticles. Blood (1996) 1.50
All-trans and 9-cis retinoic acid enhance 1,25-dihydroxyvitamin D3-induced monocytic differentiation of U937 cells. Leuk Res (1996) 1.50
Tumor antigens isolated from a patient with vitiligo and T-cell-infiltrated melanoma. Cancer Res (2001) 1.50
[A case of familial type IIa hyperlipoproteinemia with a huge intracranial xanthoma, hypertension, and periarticular bone lesions (author's transl)]. Nihon Naika Gakkai Zasshi (1980) 1.49
Effect of troglitazone on body fat distribution in type 2 diabetic patients. Diabetes Care (1999) 1.49
Structure-activity relationship of lipid A: comparison of biological activities of natural and synthetic lipid A's with different fatty acid compositions. J Biochem (1986) 1.47
Structural requirements of lipid A responsible for the functions: a study with chemically synthesized lipid A and its analogues. J Biochem (1985) 1.47
Cushing's syndrome due to primary adrenocortical nodular dysplasia, cardiac myxomas, and spotty pigmentation, complicated by sarcoidosis. Intern Med (1992) 1.46
Effect of cilostazol on soluble adhesion molecules and platelet-derived microparticles in patients with diabetes. Thromb Haemost (1998) 1.46
Molecular cloning and nucleotide sequence of complementary DNAs encoding human short chain acyl-coenzyme A dehydrogenase and the study of the molecular basis of human short chain acyl-coenzyme A dehydrogenase deficiency. J Clin Invest (1989) 1.44
Decreased albuminuria by pravastatin in hyperlipidemic diabetics. Nephron (1991) 1.44
A new ray-tracing program RIGTRACE for X-ray optical systems. J Synchrotron Radiat (2001) 1.44
Syntaxin 18, a SNAP receptor that functions in the endoplasmic reticulum, intermediate compartment, and cis-Golgi vesicle trafficking. J Biol Chem (2000) 1.44
Structure and function of chromosomes in mitosis of budding yeast. Cold Spring Harb Symp Quant Biol (1993) 1.42
Neutrophil induced oxidative injury of cardiac myocytes. A compartmented system requiring CD11b/CD18-ICAM-1 adherence. J Clin Invest (1992) 1.42
Observation of a centrality-dependent dijet asymmetry in lead-lead collisions at sqrt[S(NN)] =2.76 TeV with the ATLAS detector at the LHC. Phys Rev Lett (2010) 1.41
A method for construction of specialized transducing phage rho 11 of Bacillus subtilis. Gene (1979) 1.41
Glycemic control is a predictor of survival for diabetic patients on hemodialysis. Diabetes Care (2001) 1.40
Distinct mechanisms of platelet aggregation as a consequence of different shearing flow conditions. J Clin Invest (1998) 1.40
Adrenal-sparing adrenalectomy in hereditary bilateral phaeochromocytoma. ANZ J Surg (2001) 1.40
Suppression of tumor growth in experimental 9L gliosarcoma model by copper depletion. Neurol Med Chir (Tokyo) (1995) 1.40
Highly specific anti-digoxin antiserum from immunization with digoxin 3'-hemisuccinate-bovine serum albumin conjugate. Clin Chem (1994) 1.40
Non-penetrating vascular clips anastomosis inhibited intimal thickening under poor runoff conditions in canine autogenous vein grafts. Eur J Vasc Endovasc Surg (2001) 1.39
V-Y advancement posterior thigh fasciocutaneous flaps for total anal canal and large perianal defects. Ann Plast Surg (1996) 1.39
Measurement of dijet azimuthal decorrelations in pp collisions at sqrt(s)=7 TeV. Phys Rev Lett (2011) 1.39