Published in Structure on April 01, 2007
Steric mechanism of auto-inhibitory regulation of specific and non-specific DNA binding by the ETS transcriptional repressor ETV6. J Mol Biol (2013) 1.58
Crystal structure of the beta beta alpha-Me type II restriction endonuclease Hpy99I with target DNA. Nucleic Acids Res (2009) 1.13
Sequence-dependent sliding kinetics of p53. Proc Natl Acad Sci U S A (2012) 1.13
Cooperative DNA binding and communication across the dimer interface in the TREX2 3' --> 5'-exonuclease. J Biol Chem (2008) 0.99
Enforced presentation of an extrahelical guanine to the lesion recognition pocket of human 8-oxoguanine glycosylase, hOGG1. J Biol Chem (2012) 0.95
Insights into RNA/DNA hybrid recognition and processing by RNase H from the crystal structure of a non-specific enzyme-dsDNA complex. Cell Cycle (2008) 0.92
Experimental snapshots of a protein-DNA binding landscape. Proc Natl Acad Sci U S A (2010) 0.89
Early interrogation and recognition of DNA sequence by indirect readout. Structure (2008) 0.86
A sliding restriction enzyme pauses. Structure (2007) 0.83
Twist-open mechanism of DNA damage recognition by the Rad4/XPC nucleotide excision repair complex. Proc Natl Acad Sci U S A (2016) 0.82
A human transcription factor in search mode. Nucleic Acids Res (2015) 0.77
Mechanism of Iron-Dependent Repressor (IdeR) Activation and DNA Binding: A Molecular Dynamics and Protein Structure Network Study. PLoS Comput Biol (2015) 0.75
Eya protein phosphatase activity regulates Six1-Dach-Eya transcriptional effects in mammalian organogenesis. Nature (2003) 3.72
Replication by human DNA polymerase-iota occurs by Hoogsteen base-pairing. Nature (2004) 3.57
Functional specificity of a Hox protein mediated by the recognition of minor groove structure. Cell (2007) 3.34
Transcription corepressor CtBP is an NAD(+)-regulated dehydrogenase. Mol Cell (2002) 3.28
PHF8 mediates histone H4 lysine 20 demethylation events involved in cell cycle progression. Nature (2010) 2.91
Human DNA polymerase kappa encircles DNA: implications for mismatch extension and lesion bypass. Mol Cell (2007) 2.46
Structural basis of high-fidelity DNA synthesis by yeast DNA polymerase delta. Nat Struct Mol Biol (2009) 2.44
Rev1 employs a novel mechanism of DNA synthesis using a protein template. Science (2005) 2.37
Human DNA polymerase iota incorporates dCTP opposite template G via a G.C + Hoogsteen base pair. Structure (2005) 1.80
Structural basis for the suppression of skin cancers by DNA polymerase eta. Nature (2010) 1.73
Protein-template-directed synthesis across an acrolein-derived DNA adduct by yeast Rev1 DNA polymerase. Structure (2008) 1.72
Natural and engineered nicking endonucleases--from cleavage mechanism to engineering of strand-specificity. Nucleic Acids Res (2010) 1.66
Crystal structure of PU.1/IRF-4/DNA ternary complex. Mol Cell (2002) 1.64
Structures of the rare-cutting restriction endonuclease NotI reveal a unique metal binding fold involved in DNA binding. Structure (2008) 1.64
Hoogsteen base pair formation promotes synthesis opposite the 1,N6-ethenodeoxyadenosine lesion by human DNA polymerase iota. Nat Struct Mol Biol (2006) 1.58
Crystal structure of the SF3 helicase from adeno-associated virus type 2. Structure (2003) 1.56
Model of the brain tumor-Pumilio translation repressor complex. Genes Dev (2003) 1.46
Crystal structure of the catalytic core of human DNA polymerase kappa. Structure (2004) 1.35
Negative role of RIG-I serine 8 phosphorylation in the regulation of interferon-beta production. J Biol Chem (2010) 1.35
mRNA regulation by Puf domain proteins. Sci STKE (2006) 1.31
An incoming nucleotide imposes an anti to syn conformational change on the templating purine in the human DNA polymerase-iota active site. Structure (2006) 1.31
A view of consecutive binding events from structures of tetrameric endonuclease SfiI bound to DNA. EMBO J (2005) 1.30
Dpo4 is hindered in extending a G.T mismatch by a reverse wobble. Nat Struct Mol Biol (2004) 1.24
Structures of human Pumilio with noncognate RNAs reveal molecular mechanisms for binding promiscuity. Structure (2008) 1.24
The COMBREX project: design, methodology, and initial results. PLoS Biol (2013) 1.24
Engineering strand-specific DNA nicking enzymes from the type IIS restriction endonucleases BsaI, BsmBI, and BsmAI. J Mol Biol (2004) 1.23
RNA recognition via the SAM domain of Smaug. Mol Cell (2003) 1.22
Proximity-induced activation of human Cdc34 through heterologous dimerization. Proc Natl Acad Sci U S A (2005) 1.19
Structure of IRF-3 bound to the PRDIII-I regulatory element of the human interferon-beta enhancer. Mol Cell (2007) 1.18
Direct interaction of YidC with the Sec-independent Pf3 coat protein during its membrane protein insertion. J Biol Chem (2001) 1.16
Discovery of natural nicking endonucleases Nb.BsrDI and Nb.BtsI and engineering of top-strand nicking variants from BsrDI and BtsI. Nucleic Acids Res (2007) 1.13
Crystal structure of the restriction-modification system control element C.Bcll and mapping of its binding site. Structure (2005) 1.12
Structure of the human Rev1-DNA-dNTP ternary complex. J Mol Biol (2009) 1.12
Topology of Type II REases revisited; structural classes and the common conserved core. Nucleic Acids Res (2007) 1.11
Unusual target site disruption by the rare-cutting HNH restriction endonuclease PacI. Structure (2010) 1.11
Engineering Escherichia coli BL21(DE3) derivative strains to minimize E. coli protein contamination after purification by immobilized metal affinity chromatography. Appl Environ Microbiol (2011) 1.11
Structure of human DNA polymerase kappa inserting dATP opposite an 8-OxoG DNA lesion. PLoS One (2009) 1.09
Structure of adeno-associated virus type 2 Rep40-ADP complex: insight into nucleotide recognition and catalysis by superfamily 3 helicases. Proc Natl Acad Sci U S A (2004) 1.08
Versatility of inner membrane protein biogenesis in Escherichia coli. Mol Microbiol (2003) 1.07
Cytotoxicity of single-walled carbon nanotubes on PC12 cells. Toxicol In Vitro (2010) 1.05
Structure of NF-kappaB p50/p65 heterodimer bound to the PRDII DNA element from the interferon-beta promoter. Structure (2002) 1.04
DNA synthesis across an abasic lesion by human DNA polymerase iota. Structure (2009) 1.04
Nimodipine protects dopaminergic neurons against inflammation-mediated degeneration through inhibition of microglial activation. Neuropharmacology (2008) 1.04
Residues within the B' motif are critical for DNA binding by the superfamily 3 helicase Rep40 of adeno-associated virus type 2. J Biol Chem (2004) 1.03
Structural basis for cisplatin DNA damage tolerance by human polymerase η during cancer chemotherapy. Nat Struct Mol Biol (2012) 1.02
Structural insights into yeast DNA polymerase delta by small angle X-ray scattering. J Mol Biol (2009) 1.02
Vitamin E renders protection to PC12 cells against oxidative damage and apoptosis induced by single-walled carbon nanotubes. Toxicol In Vitro (2011) 0.96
Implications for switching restriction enzyme specificities from the structure of BstYI bound to a BglII DNA sequence. Structure (2005) 0.96
Energetic and structural considerations for the mechanism of protein sliding along DNA in the nonspecific BamHI-DNA complex. Biophys J (2003) 0.95
Artemis C-terminal region facilitates V(D)J recombination through its interactions with DNA Ligase IV and DNA-PKcs. J Exp Med (2012) 0.95
Engineering BspQI nicking enzymes and application of N.BspQI in DNA labeling and production of single-strand DNA. Protein Expr Purif (2009) 0.94
Replication across template T/U by human DNA polymerase-iota. Structure (2009) 0.94
Isolation of BsoBI restriction endonuclease variants with altered substrate specificity. J Mol Biol (2003) 0.94
Further pharmacological evidence of the neuroprotective effect of catalpol from Rehmannia glutinosa. Phytomedicine (2008) 0.94
Cofactor requirement of HpyAV restriction endonuclease. PLoS One (2010) 0.94
Crystal structure of BstYI at 1.85A resolution: a thermophilic restriction endonuclease with overlapping specificities to BamHI and BglII. J Mol Biol (2004) 0.93
Co-occupancy of two Pumilio molecules on a single hunchback NRE. RNA (2009) 0.92
Catalytic domain of restriction endonuclease BmrI as a cleavage module for engineering endonucleases with novel substrate specificities. Nucleic Acids Res (2007) 0.92
Structural basis for error-free replication of oxidatively damaged DNA by yeast DNA polymerase η. Structure (2010) 0.92
The ins and outs of bcr-abl inhibition. Genes Cancer (2012) 0.91
Catalpol protects primary cultured astrocytes from in vitro ischemia-induced damage. Int J Dev Neurosci (2008) 0.91
Human DNA polymerase η is pre-aligned for dNTP binding and catalysis. J Mol Biol (2011) 0.91
Solution structure of the Vts1 SAM domain in the presence of RNA. J Mol Biol (2005) 0.90
Structure and dynamics of the second CARD of human RIG-I provide mechanistic insights into regulation of RIG-I activation. Structure (2012) 0.90
The architecture of yeast DNA polymerase ζ. Cell Rep (2013) 0.87
Crystallization and characterization of PU.1/IRF-4/DNA ternary complex. J Struct Biol (2002) 0.86
Structural basis of DNA ligase IV-Artemis interaction in nonhomologous end-joining. Cell Rep (2012) 0.86
Effects of catalpol on mitochondrial function and working memory in mice after lipopolysaccharide-induced acute systemic inflammation. Exp Toxicol Pathol (2008) 0.85
DNA synthesis across an abasic lesion by yeast REV1 DNA polymerase. J Mol Biol (2010) 0.85
Deoxynucleotide triphosphate binding mode conserved in Y family DNA polymerases. Mol Cell Biol (2003) 0.85
Expression and purification of BmrI restriction endonuclease and its N-terminal cleavage domain variants. Protein Expr Purif (2007) 0.84
Characterization of thermo-stable endoinulinase from a new strain Bacillus smithii T7. Appl Biochem Biotechnol (2008) 0.84
Structural insights into the assembly and shape of Type III restriction-modification (R-M) EcoP15I complex by small-angle X-ray scattering. J Mol Biol (2012) 0.84
Rational design of a chimeric endonuclease targeted to NotI recognition site. Protein Eng Des Sel (2007) 0.84
Translational repressors in Drosophila. Trends Genet (2002) 0.83
Crystallization and preliminary crystallographic analysis of the type IIL restriction enzyme MmeI in complex with DNA. Acta Crystallogr Sect F Struct Biol Cryst Commun (2011) 0.82
Increasing cleavage specificity and activity of restriction endonuclease KpnI. Nucleic Acids Res (2013) 0.82
Nitrogen-containing flavonoid analogues as CDK1/cyclin B inhibitors: synthesis, SAR analysis, and biological activity. Bioorg Med Chem (2008) 0.82
Role of human DNA polymerase κ in extension opposite from a cis-syn thymine dimer. J Mol Biol (2011) 0.81
Isoflavonoids from Astragalus mongholicus protect PC12 cells from toxicity induced by L-glutamate. J Ethnopharmacol (2005) 0.81
Asymmetric DNA recognition by the OkrAI endonuclease, an isoschizomer of BamHI. Nucleic Acids Res (2010) 0.81
An EM view of the FokI synaptic complex by single particle analysis. J Mol Biol (2007) 0.80
TspMI, a thermostable isoschizomer of XmaI (5'C/CCGGG3'): characterization and single molecule imaging with DNA. Appl Microbiol Biotechnol (2006) 0.79
Glucocorticoid receptor-like Zn(Cys)4 motifs in BslI restriction endonuclease. J Mol Biol (2003) 0.79
Rational design of a fusion partner for membrane protein expression in E. coli. Protein Sci (2009) 0.78
Structures of apo IRF-3 and IRF-7 DNA binding domains: effect of loop L1 on DNA binding. Nucleic Acids Res (2011) 0.78
Effects of isocamptothecin, a novel camptothecin analogue, on proliferation, apoptosis and telomerase activity in HaCaT cells. Exp Dermatol (2008) 0.78
Crystallization and characterization of Smaug: a novel RNA-binding motif. Biochem Biophys Res Commun (2002) 0.77
Cloning of NruI and Sbo13I restriction and modification sstems in E. coli and amino acid sequence comparison of M.NruI and M.Sbo13I with other amino-methyltransferases. BMC Res Notes (2010) 0.77
Crystallization of restriction endonuclease SfiI in complex with DNA. Acta Crystallogr D Biol Crystallogr (2003) 0.77
Efficient targeted pDNA/siRNA delivery with folate-low-molecular-weight polyethyleneimine-modified pullulan as non-viral carrier. Mater Sci Eng C Mater Biol Appl (2013) 0.77
Purification and characterization of Ulva pertusa Kjellm alkaline phosphatase. Prep Biochem Biotechnol (2003) 0.77
[Screening of antineoplastic components in Radix et Rhizoma Rhei using chromatographic fingerprints]. Se Pu (2005) 0.76