Published in J Mol Biol on November 05, 2008
The structures of the anti-tuberculosis antibiotics viomycin and capreomycin bound to the 70S ribosome. Nat Struct Mol Biol (2010) 1.42
Visualizing transient low-populated structures of RNA. Nature (2012) 1.36
Binding of aminoglycoside antibiotics to helix 69 of 23S rRNA. Nucleic Acids Res (2010) 1.05
Helix 69 in 23S rRNA modulates decoding by wild type and suppressor tRNAs. Mol Genet Genomics (2009) 0.94
Probing conformational states of modified helix 69 in 50S ribosomes. J Am Chem Soc (2011) 0.90
Specificity and kinetics of 23S rRNA modification enzymes RlmH and RluD. RNA (2010) 0.90
The antibiotic thermorubin inhibits protein synthesis by binding to inter-subunit bridge B2a of the ribosome. J Mol Biol (2012) 0.88
Role of pseudouridine in structural rearrangements of helix 69 during bacterial ribosome assembly. ACS Chem Biol (2012) 0.87
Comparison of solution conformations and stabilities of modified helix 69 rRNA analogs from bacteria and human. Biopolymers (2011) 0.87
Structure modulation of helix 69 from Escherichia coli 23S ribosomal RNA by pseudouridylations. Nucleic Acids Res (2013) 0.84
Functional interactions by transfer RNAs in the ribosome. FEBS Lett (2010) 0.82
Ribosomal initiation complex-driven changes in the stability and dynamics of initiation factor 2 regulate the fidelity of translation initiation. J Mol Biol (2015) 0.81
Roles of helix H69 of 23S rRNA in translation initiation. Proc Natl Acad Sci U S A (2015) 0.78
Interplay of the bacterial ribosomal A-site, S12 protein mutations and paromomycin binding: a molecular dynamics study. PLoS One (2014) 0.78
Directional transition from initiation to elongation in bacterial translation. Nucleic Acids Res (2015) 0.78
Dynamic contact network between ribosomal subunits enables rapid large-scale rotation during spontaneous translocation. Nucleic Acids Res (2015) 0.78
The effects of disruptions in ribosomal active sites and in intersubunit contacts on ribosomal degradation in Escherichia coli. Sci Rep (2015) 0.77
Intersubunit Bridges of the Bacterial Ribosome. J Mol Biol (2016) 0.77
Cisplatin Targeting of Bacterial Ribosomal RNA Hairpins. Int J Mol Sci (2015) 0.77
Selection of heptapeptides that bind helix 69 of bacterial 23S ribosomal RNA. Bioorg Med Chem (2013) 0.77
The development of peptide ligands that target helix 69 rRNA of bacterial ribosomes. Bioorg Med Chem (2016) 0.75
Modulation of conformational changes in helix 69 mutants by pseudouridine modifications. Biophys Chem (2015) 0.75
Mechanism of blebbistatin inhibition of myosin II. J Biol Chem (2004) 5.45
AlkB restores the biological function of mRNA and tRNA inactivated by chemical methylation. Mol Cell (2004) 2.26
The autoimmune regulator PHD finger binds to non-methylated histone H3K4 to activate gene expression. EMBO Rep (2008) 2.22
Lys34 of translation elongation factor EF-P is hydroxylated by YfcM. Nat Chem Biol (2012) 1.45
Distinct XPPX sequence motifs induce ribosome stalling, which is rescued by the translation elongation factor EF-P. Proc Natl Acad Sci U S A (2013) 1.30
Alternatively spliced exon B of myosin Va is essential for binding the tail-associated light chain shared by dynein. Biochemistry (2006) 1.17
Identification of pseudouridine methyltransferase in Escherichia coli. RNA (2008) 1.11
Definition of bases in 23S rRNA essential for ribosomal subunit association. RNA (2004) 1.10
Analysis of the function of E. coli 23S rRNA helix-loop 69 by mutagenesis. BMC Mol Biol (2005) 1.10
Erythromycin- and chloramphenicol-induced ribosomal assembly defects are secondary effects of protein synthesis inhibition. Antimicrob Agents Chemother (2008) 1.09
Ribosome assembly in Escherichia coli strains lacking the RNA helicase DeaD/CsdA or DbpA. FEBS J (2008) 1.05
Subribosomal particle analysis reveals the stages of bacterial ribosome assembly at which rRNA nucleotides are modified. RNA (2010) 1.03
Ribosome reactivation by replacement of damaged proteins. Mol Microbiol (2009) 1.03
Selective perturbation of the myosin recovery stroke by point mutations at the base of the lever arm affects ATP hydrolysis and phosphate release. J Biol Chem (2007) 1.01
Ribosome degradation in growing bacteria. EMBO Rep (2011) 0.97
Protected nucleotide G2608 in 23S rRNA confers resistance to oxazolidinones in E. coli. Biochem Biophys Res Commun (2005) 0.95
Antibiotic-induced ribosomal assembly defects result from changes in the synthesis of ribosomal proteins. Mol Microbiol (2011) 0.93
Drug effect prediction by polypharmacology-based interaction profiling. J Chem Inf Model (2011) 0.92
Identification of nucleotides in E. coli 16S rRNA essential for ribosome subunit association. RNA (2006) 0.92
Structural evidence for non-canonical binding of Ca2+ to a canonical EF-hand of a conventional myosin. J Biol Chem (2005) 0.92
Substrate specificity of the pseudouridine synthase RluD in Escherichia coli. FEBS J (2007) 0.90
Myosin cleft closure determines the energetics of the actomyosin interaction. FASEB J (2010) 0.90
Specificity and kinetics of 23S rRNA modification enzymes RlmH and RluD. RNA (2010) 0.90
Troubleshooting coupled in vitro transcription-translation system derived from Escherichia coli cells: synthesis of high-yield fully active proteins. Nucleic Acids Res (2006) 0.89
Functional interaction between RNase III and the Escherichia coli ribosome. BMC Mol Biol (2003) 0.89
Extended intermolecular interactions in a serine protease-canonical inhibitor complex account for strong and highly specific inhibition. J Mol Biol (2005) 0.88
Design of multi-binding-site inhibitors, ligand efficiency, and consensus screening of avian influenza H5N1 wild-type neuraminidase and of the oseltamivir-resistant H274Y variant. J Chem Inf Model (2008) 0.87
Importance of transient structures during post-transcriptional refolding of the pre-23S rRNA and ribosomal large subunit assembly. J Mol Biol (2004) 0.87
Functional importance of the 3'-terminal adenosine of tRNA in ribosomal translation. J Biol Chem (2002) 0.85
DrugLogit: logistic discrimination between drugs and nondrugs including disease-specificity by assigning probabilities based on molecular properties. J Chem Inf Model (2012) 0.84
Accessibility of phosphates in domain I of 23 S rRNA in the ribosomal 50 S subunit as detected by R(P) phosphorothioates. Biochim Biophys Acta (2002) 0.83
Pseudouridylation of 23S rRNA helix 69 promotes peptide release by release factor RF2 but not by release factor RF1. Biochimie (2011) 0.83
QSPR modeling of solubility of polyaromatic hydrocarbons and fullerene in 1-octanol and n-heptane. J Phys Chem B (2007) 0.82
In vitro model of neurotoxicity of Abeta 1-42 and neuroprotection by a pentapeptide: irreversible events during the first hour. Neurobiol Dis (2004) 0.81
Initiation with elongator tRNAs. J Bacteriol (2013) 0.80
Drug efficiency indices for improvement of molecular docking scoring functions. J Comput Chem (2010) 0.80
Combined approach using ligand efficiency, cross-docking, and antitarget hits for wild-type and drug-resistant Y181C HIV-1 reverse transcriptase. J Chem Inf Model (2011) 0.79
DYNLL2 dynein light chain binds to an extended linear motif of myosin 5a tail that has structural plasticity. Biochemistry (2014) 0.78
Contribution of 2D and 3D structural features of drug molecules in the prediction of Drug Profile Matching. J Chem Inf Model (2012) 0.78
Modeling the toxicity of chemicals to Tetrahymena pyriformis using heuristic multilinear regression and heuristic back-propagation neural networks. J Chem Inf Model (2007) 0.78
Conformational dynamics of titin PEVK explored with FRET spectroscopy. Biophys J (2012) 0.76
Different sensitivity of H69 modification enzymes RluD and RlmH to mutations in Escherichia coli 23S rRNA. Biochimie (2012) 0.75
Structure-based calculation of binding affinities of alpha 2A-adrenoceptor agonists. ChemMedChem (2007) 0.75