Published in Biochem Biophys Res Commun on April 09, 2007
Studies of bone morphogenetic protein-based surgical repair. Adv Drug Deliv Rev (2012) 1.13
The role of small molecules in musculoskeletal regeneration. Regen Med (2012) 0.90
Stepwise differentiation of pluripotent stem cells into osteoblasts using four small molecules under serum-free and feeder-free conditions. Stem Cell Reports (2014) 0.88
Bioactive factors for tissue regeneration: state of the art. Muscles Ligaments Tendons J (2012) 0.79
Slowly Delivered Icariin/Allogeneic Bone Marrow-Derived Mesenchymal Stem Cells to Promote the Healing of Calvarial Critical-Size Bone Defects. Stem Cells Int (2016) 0.75
A large-area, flexible pressure sensor matrix with organic field-effect transistors for artificial skin applications. Proc Natl Acad Sci U S A (2004) 8.15
Suppression of aging in mice by the hormone Klotho. Science (2005) 8.11
Conformable, flexible, large-area networks of pressure and thermal sensors with organic transistor active matrixes. Proc Natl Acad Sci U S A (2005) 5.37
PPARgamma insufficiency enhances osteogenesis through osteoblast formation from bone marrow progenitors. J Clin Invest (2004) 5.29
RANKL maintains bone homeostasis through c-Fos-dependent induction of interferon-beta. Nature (2002) 4.44
Conserved factors regulate signalling in Arabidopsis thaliana shoot and root stem cell organizers. Nature (2007) 3.84
Transcriptional regulation of endochondral ossification by HIF-2alpha during skeletal growth and osteoarthritis development. Nat Med (2010) 3.59
Whole-genome analysis of the SHORT-ROOT developmental pathway in Arabidopsis. PLoS Biol (2006) 3.52
Prevalence of knee osteoarthritis, lumbar spondylosis, and osteoporosis in Japanese men and women: the research on osteoarthritis/osteoporosis against disability study. J Bone Miner Metab (2009) 3.27
An aspartic acid repeat polymorphism in asporin inhibits chondrogenesis and increases susceptibility to osteoarthritis. Nat Genet (2005) 3.00
Ihh signaling is directly required for the osteoblast lineage in the endochondral skeleton. Development (2004) 2.39
Regulation of osteoclast apoptosis by ubiquitylation of proapoptotic BH3-only Bcl-2 family member Bim. EMBO J (2003) 2.30
Contribution of runt-related transcription factor 2 to the pathogenesis of osteoarthritis in mice after induction of knee joint instability. Arthritis Rheum (2006) 2.19
The combination of SOX5, SOX6, and SOX9 (the SOX trio) provides signals sufficient for induction of permanent cartilage. Arthritis Rheum (2004) 2.08
Opposing extracellular signal-regulated kinase and Akt pathways control Schwann cell myelination. J Neurosci (2004) 2.04
Cyclic GMP-dependent protein kinase II is a molecular switch from proliferation to hypertrophic differentiation of chondrocytes. Genes Dev (2004) 2.00
A "super-aged" society and the "locomotive syndrome". J Orthop Sci (2008) 1.87
Role of RANKL in physiological and pathological bone resorption and therapeutics targeting the RANKL-RANK signaling system. Immunol Rev (2005) 1.81
Meta-analysis of genome-wide association studies confirms a susceptibility locus for knee osteoarthritis on chromosome 7q22. Ann Rheum Dis (2010) 1.75
Prognostic factors for patients with spinal metastases from lung cancer. Spine (Phila Pa 1976) (2006) 1.72
Suppressive function of androgen receptor in bone resorption. Proc Natl Acad Sci U S A (2003) 1.72
Mechanisms regulating SHORT-ROOT intercellular movement. Curr Biol (2004) 1.70
Klotho gene polymorphisms associated with bone density of aged postmenopausal women. J Bone Miner Res (2002) 1.69
A functional single nucleotide polymorphism in the core promoter region of CALM1 is associated with hip osteoarthritis in Japanese. Hum Mol Genet (2005) 1.67
Lactosylated poly(ethylene glycol)-siRNA conjugate through acid-labile beta-thiopropionate linkage to construct pH-sensitive polyion complex micelles achieving enhanced gene silencing in hepatoma cells. J Am Chem Soc (2005) 1.66
Reduced pain hypersensitivity and inflammation in mice lacking microsomal prostaglandin e synthase-1. J Biol Chem (2004) 1.65
CpG island methylator phenotype is a strong determinant of poor prognosis in neuroblastomas. Cancer Res (2005) 1.57
Runx2 determines bone maturity and turnover rate in postnatal bone development and is involved in bone loss in estrogen deficiency. Dev Dyn (2007) 1.56
Akt1 in osteoblasts and osteoclasts controls bone remodeling. PLoS One (2007) 1.56
Statistics for orthopedic surgery 2006-2007: data from the Japanese Diagnosis Procedure Combination database. J Orthop Sci (2010) 1.55
Callose biosynthesis regulates symplastic trafficking during root development. Dev Cell (2011) 1.55
Patched1 haploinsufficiency increases adult bone mass and modulates Gli3 repressor activity. Dev Cell (2008) 1.54
Venous sampling for fibroblast growth factor-23 confirms preoperative diagnosis of tumor-induced osteomalacia. J Clin Endocrinol Metab (2004) 1.54
A comparison of the defective granulopoiesis in childhood cyclic neutropenia and in severe congenital neutropenia. Haematologica (2005) 1.53
Prediction of strength and strain of the proximal femur by a CT-based finite element method. J Biomech (2006) 1.53
3D spheroid culture system on micropatterned substrates for improved differentiation efficiency of multipotent mesenchymal stem cells. Biomaterials (2009) 1.50
Negative regulation of osteoclastogenesis by ectodomain shedding of receptor activator of NF-kappaB ligand. J Biol Chem (2006) 1.49
Lack of a chondroprotective effect of cyclooxygenase 2 inhibition in a surgically induced model of osteoarthritis in mice. Arthritis Rheum (2012) 1.49
Reduction of Peritendinous adhesions by hydrogel containing biocompatible phospholipid polymer MPC for tendon repair. J Bone Joint Surg Am (2011) 1.48
Involvement of endogenous bone morphogenetic protein (BMP) 2 and BMP6 in bone formation. J Biol Chem (2005) 1.47
Stimulatory G protein directly regulates hypertrophic differentiation of growth plate cartilage in vivo. Proc Natl Acad Sci U S A (2004) 1.46
Regulation of bone formation by adiponectin through autocrine/paracrine and endocrine pathways. J Cell Biochem (2006) 1.46
Dnm3os, a non-coding RNA, is required for normal growth and skeletal development in mice. Dev Dyn (2008) 1.45
Heparin potentiates the in vivo ectopic bone formation induced by bone morphogenetic protein-2. J Biol Chem (2006) 1.45
Growth factor treatment and genetic manipulation stimulate neurogenesis and oligodendrogenesis by endogenous neural progenitors in the injured adult spinal cord. J Neurosci (2006) 1.43
Cohort profile: research on Osteoarthritis/Osteoporosis Against Disability study. Int J Epidemiol (2009) 1.39
C/EBPβ and RUNX2 cooperate to degrade cartilage with MMP-13 as the target and HIF-2α as the inducer in chondrocytes. Hum Mol Genet (2011) 1.37
Factors associated with mortality following hip fracture in Japan. J Bone Miner Metab (2006) 1.37
S100A1 and S100B, transcriptional targets of SOX trio, inhibit terminal differentiation of chondrocytes. EMBO Rep (2007) 1.36
Highly efficient ex vivo expansion of human hematopoietic stem cells using Delta1-Fc chimeric protein. Stem Cells (2006) 1.35
PEG-detachable polyplex micelles based on disulfide-linked block catiomers as bioresponsive nonviral gene vectors. J Am Chem Soc (2008) 1.35
Differential regulation of cell migration, actin stress fiber organization, and cell transformation by functional domains of Crk-associated substrate. J Biol Chem (2002) 1.35
The canonical Wnt signaling pathway promotes chondrocyte differentiation in a Sox9-dependent manner. Biochem Biophys Res Commun (2005) 1.33
Wiskott Aldrich syndrome protein (WASP) and N-WASP are critical for T cell development. Proc Natl Acad Sci U S A (2007) 1.31
Surgical results and related factors for ossification of posterior longitudinal ligament of the thoracic spine: a multi-institutional retrospective study. Spine (Phila Pa 1976) (2008) 1.31
Insulin receptor substrate-2 maintains predominance of anabolic function over catabolic function of osteoblasts. J Cell Biol (2002) 1.30
Non-cell-autonomous microRNA165 acts in a dose-dependent manner to regulate multiple differentiation status in the Arabidopsis root. Development (2011) 1.30
GSK-3beta controls osteogenesis through regulating Runx2 activity. PLoS One (2007) 1.29