Published in ACS Chem Biol on April 27, 2007
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Organization of intracellular reactions with rationally designed RNA assemblies. Science (2011) 3.65
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Two interconverting Fe(IV) intermediates in aliphatic chlorination by the halogenase CytC3. Nat Chem Biol (2007) 3.33
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Functional specificity among ribosomal proteins regulates gene expression. Cell (2007) 3.22
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New antibiotics from bacterial natural products. Nat Biotechnol (2006) 2.72
The evolution of gene collectives: How natural selection drives chemical innovation. Proc Natl Acad Sci U S A (2008) 2.71
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The pathogen-associated iroA gene cluster mediates bacterial evasion of lipocalin 2. Proc Natl Acad Sci U S A (2006) 2.63
BluB cannibalizes flavin to form the lower ligand of vitamin B12. Nature (2007) 2.53
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Crystal structure of the non-haem iron halogenase SyrB2 in syringomycin biosynthesis. Nature (2006) 2.52
How pathogenic bacteria evade mammalian sabotage in the battle for iron. Nat Chem Biol (2006) 2.45
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Dynamic thiolation-thioesterase structure of a non-ribosomal peptide synthetase. Nature (2008) 2.39
The Orientia tsutsugamushi genome reveals massive proliferation of conjugative type IV secretion system and host-cell interaction genes. Proc Natl Acad Sci U S A (2007) 2.35
Human cell proteins and human immunodeficiency virus DNA integration. Front Biosci (2004) 2.32
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Engineering synthetic TAL effectors with orthogonal target sites. Nucleic Acids Res (2012) 2.25
Nature's inventory of halogenation catalysts: oxidative strategies predominate. Chem Rev (2006) 2.24
Thirteen posttranslational modifications convert a 14-residue peptide into the antibiotic thiocillin. Proc Natl Acad Sci U S A (2009) 2.22
Facile detection of acyl and peptidyl intermediates on thiotemplate carrier domains via phosphopantetheinyl elimination reactions during tandem mass spectrometry. Biochemistry (2006) 2.22
Spatially ordered dynamics of the bacterial carbon fixation machinery. Science (2010) 2.22
The identification of bacillaene, the product of the PksX megacomplex in Bacillus subtilis. Proc Natl Acad Sci U S A (2007) 2.22
Global histone acetylation induces functional genomic reorganization at mammalian nuclear pore complexes. Genes Dev (2008) 2.17
Induction of biogenic magnetization and redox control by a component of the target of rapamycin complex 1 signaling pathway. PLoS Biol (2012) 2.15
SyrB2 in syringomycin E biosynthesis is a nonheme FeII alpha-ketoglutarate- and O2-dependent halogenase. Proc Natl Acad Sci U S A (2005) 2.12
Genomic mapping of RNA polymerase II reveals sites of co-transcriptional regulation in human cells. Genome Biol (2005) 2.11
The genome-wide localization of Rsc9, a component of the RSC chromatin-remodeling complex, changes in response to stress. Mol Cell (2002) 2.10
Halogenation strategies in natural product biosynthesis. Chem Biol (2008) 2.08
A genome-wide in situ hybridization map of RNA-binding proteins reveals anatomically restricted expression in the developing mouse brain. BMC Dev Biol (2005) 2.08
Sequencing the unsequenceable: expanded CGG-repeat alleles of the fragile X gene. Genome Res (2012) 2.04
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Genetically encoded short peptide tag for versatile protein labeling by Sfp phosphopantetheinyl transferase. Proc Natl Acad Sci U S A (2005) 2.03
Vancomycin assembly: nature's way. Angew Chem Int Ed Engl (2003) 1.99
A subset of membrane-associated proteins is ubiquitinated in response to mutations in the endoplasmic reticulum degradation machinery. Proc Natl Acad Sci U S A (2003) 1.98
A systems view of mRNP biology. Genes Dev (2004) 1.98
Association of race and sites of care with pressure ulcers in high-risk nursing home residents. JAMA (2011) 1.98
Receptor-regulated dynamic S-nitrosylation of endothelial nitric-oxide synthase in vascular endothelial cells. J Biol Chem (2005) 1.96
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Incorporation of glucose analogs by GtfE and GtfD from the vancomycin biosynthetic pathway to generate variant glycopeptides. Chem Biol (2002) 1.90
A singular enzymatic megacomplex from Bacillus subtilis. Proc Natl Acad Sci U S A (2006) 1.89
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Ufd1 exhibits the AAA-ATPase fold with two distinct ubiquitin interaction sites. Structure (2005) 1.86
S6K directly phosphorylates IRS-1 on Ser-270 to promote insulin resistance in response to TNF-(alpha) signaling through IKK2. J Biol Chem (2008) 1.85
Labeling proteins with small molecules by site-specific posttranslational modification. J Am Chem Soc (2004) 1.84
Macrophage infiltration into adipose tissue may promote angiogenesis for adipose tissue remodeling in obesity. Am J Physiol Endocrinol Metab (2008) 1.84
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CARM1 regulates estrogen-stimulated breast cancer growth through up-regulation of E2F1. Cancer Res (2008) 1.83
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Robust in vitro activity of RebF and RebH, a two-component reductase/halogenase, generating 7-chlorotryptophan during rebeccamycin biosynthesis. Proc Natl Acad Sci U S A (2005) 1.82
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Yersiniabactin synthetase: a four-protein assembly line producing the nonribosomal peptide/polyketide hybrid siderophore of Yersinia pestis. Chem Biol (2002) 1.75
A transglutaminase homologue as a condensation catalyst in antibiotic assembly lines. Nature (2007) 1.74
Cystic fibrosis transmembrane conductance regulator and caveolin-1 regulate epithelial cell internalization of Pseudomonas aeruginosa. Am J Physiol Cell Physiol (2009) 1.72
Nuclear transport as a target for cell growth. Drug Discov Today (2003) 1.72
Uncoupling of inflammation and insulin resistance by NF-kappaB in transgenic mice through elevated energy expenditure. J Biol Chem (2009) 1.71
Lmx1b is essential for the development of serotonergic neurons. Nat Neurosci (2003) 1.70
Chlorination by a long-lived intermediate in the mechanism of flavin-dependent halogenases. Biochemistry (2007) 1.69
Substrate-triggered formation and remarkable stability of the C-H bond-cleaving chloroferryl intermediate in the aliphatic halogenase, SyrB2. Biochemistry (2009) 1.69
Terrequinone A biosynthesis through L-tryptophan oxidation, dimerization and bisprenylation. Nat Chem Biol (2007) 1.68
Structural basis for the selectivity of the external thioesterase of the surfactin synthetase. Nature (2008) 1.66