Published in Mol Endocrinol on August 11, 2005
Targeted inhibition of miRNA maturation with morpholinos reveals a role for miR-375 in pancreatic islet development. PLoS Biol (2007) 3.04
Targeted ablation of beta cells in the embryonic zebrafish pancreas using E. coli nitroreductase. Mech Dev (2006) 3.02
Decreased dissolution of ZnO by iron doping yields nanoparticles with reduced toxicity in the rodent lung and zebrafish embryos. ACS Nano (2011) 1.75
On the diabetic menu: zebrafish as a model for pancreas development and function. Bioessays (2009) 1.38
Positional cloning of "Lisch-Like", a candidate modifier of susceptibility to type 2 diabetes in mice. PLoS Genet (2008) 1.10
Transcriptional profiling of endogenous germ layer precursor cells identifies dusp4 as an essential gene in zebrafish endoderm specification. Proc Natl Acad Sci U S A (2008) 0.98
Zebrafish usp39 mutation leads to rb1 mRNA splicing defect and pituitary lineage expansion. PLoS Genet (2011) 0.92
Antagonistic interactions of hedgehog, Bmp and retinoic acid signals control zebrafish endocrine pancreas development. Development (2011) 0.80
Carbonic anhydrase 5 regulates acid-base homeostasis in zebrafish. PLoS One (2012) 0.76
Learning to Fish with Genetics: A Primer on the Vertebrate Model Danio rerio. Genetics (2016) 0.75
Mammalian TOR complex 2 controls the actin cytoskeleton and is rapamycin insensitive. Nat Cell Biol (2004) 12.12
Heritable gene targeting in zebrafish using customized TALENs. Nat Biotechnol (2011) 8.34
Transplantation and in vivo imaging of multilineage engraftment in zebrafish bloodless mutants. Nat Immunol (2003) 5.73
Skeletal muscle-specific ablation of raptor, but not of rictor, causes metabolic changes and results in muscle dystrophy. Cell Metab (2008) 4.91
Myc-induced T cell leukemia in transgenic zebrafish. Science (2003) 3.15
Chromosomal deletions and inversions mediated by TALENs and CRISPR/Cas in zebrafish. Nucleic Acids Res (2013) 2.73
Ribosomal protein S19 deficiency in zebrafish leads to developmental abnormalities and defective erythropoiesis through activation of p53 protein family. Blood (2008) 2.68
TALEN-mediated precise genome modification by homologous recombination in zebrafish. Nat Methods (2013) 2.64
ER71 acts downstream of BMP, Notch, and Wnt signaling in blood and vessel progenitor specification. Cell Stem Cell (2008) 2.46
Ets1-related protein is a key regulator of vasculogenesis in zebrafish. PLoS Biol (2006) 2.35
TIF1gamma controls erythroid cell fate by regulating transcription elongation. Cell (2010) 2.33
Rapid analysis of angiogenesis drugs in a live fluorescent zebrafish assay. Arterioscler Thromb Vasc Biol (2003) 2.26
Efficient genome-wide mutagenesis of zebrafish genes by retroviral insertions. Proc Natl Acad Sci U S A (2007) 1.96
Cloned zebrafish by nuclear transfer from long-term-cultured cells. Nat Biotechnol (2002) 1.89
Decreased dissolution of ZnO by iron doping yields nanoparticles with reduced toxicity in the rodent lung and zebrafish embryos. ACS Nano (2011) 1.75
Early hypercytokinemia is associated with interferon-induced transmembrane protein-3 dysfunction and predictive of fatal H7N9 infection. Proc Natl Acad Sci U S A (2013) 1.74
The microRNA miR-433 promotes renal fibrosis by amplifying the TGF-β/Smad3-Azin1 pathway. Kidney Int (2013) 1.72
Use of a high-throughput screening approach coupled with in vivo zebrafish embryo screening to develop hazard ranking for engineered nanomaterials. ACS Nano (2011) 1.68
Characterization of embryonic globin genes of the zebrafish. Dev Biol (2003) 1.65
The zebrafish moonshine gene encodes transcriptional intermediary factor 1gamma, an essential regulator of hematopoiesis. PLoS Biol (2004) 1.64
Identification of novel vascular endothelial-specific genes by the microarray analysis of the zebrafish cloche mutants. Blood (2005) 1.64
Interplay among Etsrp/ER71, Scl, and Alk8 signaling controls endothelial and myeloid cell formation. Blood (2008) 1.51
A novel mitochondrial matrix serine/threonine protein phosphatase regulates the mitochondria permeability transition pore and is essential for cellular survival and development. Genes Dev (2007) 1.49
A large-scale zebrafish gene knockout resource for the genome-wide study of gene function. Genome Res (2013) 1.48
Wnt5 signaling in vertebrate pancreas development. BMC Biol (2005) 1.45
Surface defects on plate-shaped silver nanoparticles contribute to its hazard potential in a fish gill cell line and zebrafish embryos. ACS Nano (2012) 1.32
Sustained activation of mTORC1 in skeletal muscle inhibits constitutive and starvation-induced autophagy and causes a severe, late-onset myopathy. Cell Metab (2013) 1.32
Analyses of pancreas development by generation of gfp transgenic zebrafish using an exocrine pancreas-specific elastaseA gene promoter. Exp Cell Res (2006) 1.28
Cranial vasculature in zebrafish forms by angioblast cluster-derived angiogenesis. Dev Biol (2010) 1.27
Synapse loss in cortex of agrin-deficient mice after genetic rescue of perinatal death. J Neurosci (2007) 1.27
Visualization of monoaminergic neurons and neurotoxicity of MPTP in live transgenic zebrafish. Dev Biol (2007) 1.26
Identification of a lectin causing the degeneration of neuronal processes using engineered embryonic stem cells. Nat Neurosci (2007) 1.25
Mutation in sodium-calcium exchanger 1 (NCX1) causes cardiac fibrillation in zebrafish. Proc Natl Acad Sci U S A (2005) 1.24
Overexpression of mini-agrin in skeletal muscle increases muscle integrity and regenerative capacity in laminin-alpha2-deficient mice. FASEB J (2005) 1.18
Vascular endothelial and endocardial progenitors differentiate as cardiomyocytes in the absence of Etsrp/Etv2 function. Development (2011) 1.17
Identification of vasculature-specific genes by microarray analysis of Etsrp/Etv2 overexpressing zebrafish embryos. Dev Dyn (2009) 1.16
Modified bacterial artificial chromosomes for zebrafish transgenesis. Methods (2006) 1.16
Linker molecules between laminins and dystroglycan ameliorate laminin-alpha2-deficient muscular dystrophy at all disease stages. J Cell Biol (2007) 1.15
Ribosomal protein L11 mutation in zebrafish leads to haematopoietic and metabolic defects. Br J Haematol (2010) 1.10
Smad7 suppresses renal fibrosis via altering expression of TGF-β/Smad3-regulated microRNAs. Mol Ther (2012) 1.10
Migration of zebrafish spinal motor nerves into the periphery requires multiple myotome-derived cues. Dev Biol (2002) 1.10
The neurite outgrowth inhibitor Nogo-A promotes denervation in an amyotrophic lateral sclerosis model. EMBO Rep (2006) 1.09
Reverse genetic approaches in zebrafish. J Genet Genomics (2012) 1.09
Pituitary corticotroph ontogeny and regulation in transgenic zebrafish. Mol Endocrinol (2003) 1.09
p53 family in development. Mech Dev (2008) 1.08
High content screening in zebrafish speeds up hazard ranking of transition metal oxide nanoparticles. ACS Nano (2011) 1.08
Optogenetic control of transcription in zebrafish. PLoS One (2012) 1.07
Scl isoforms act downstream of etsrp to specify angioblasts and definitive hematopoietic stem cells. Blood (2010) 1.06
NXT2 is required for embryonic heart development in zebrafish. BMC Dev Biol (2005) 1.06
Targeting zebrafish and murine pituitary corticotroph tumors with a cyclin-dependent kinase (CDK) inhibitor. Proc Natl Acad Sci U S A (2011) 1.05
The LTR enhancer of ERV-9 human endogenous retrovirus is active in oocytes and progenitor cells in transgenic zebrafish and humans. Proc Natl Acad Sci U S A (2004) 1.05
Microarray analysis of zebrafish cloche mutant using amplified cDNA and identification of potential downstream target genes. Dev Dyn (2005) 1.04
Lens regeneration in axolotl: new evidence of developmental plasticity. BMC Biol (2012) 1.03
Src-family kinases stabilize the neuromuscular synapse in vivo via protein interactions, phosphorylation, and cytoskeletal linkage of acetylcholine receptors. J Neurosci (2005) 1.03
Muscle-selective synaptic disassembly and reorganization in MuSK antibody positive MG mice. Exp Neurol (2011) 1.03
A novel xenograft model in zebrafish for high-resolution investigating dynamics of neovascularization in tumors. PLoS One (2011) 1.03
The zebrafish as a model for human disease. Front Biosci (2002) 1.02
Zebrafish as a developmental model organism for pediatric research. Pediatr Res (2008) 1.00
Arterial and venous progenitors of the major axial vessels originate at distinct locations. Dev Cell (2013) 0.99
Na,K-ATPase alpha2 and Ncx4a regulate zebrafish left-right patterning. Development (2007) 0.98
C1q-like inhibits p53-mediated apoptosis and controls normal hematopoiesis during zebrafish embryogenesis. Dev Biol (2008) 0.98
Discovery and characterization of novel vascular and hematopoietic genes downstream of etsrp in zebrafish. PLoS One (2009) 0.98
Generation and propagation of an anomalous vortex beam. Opt Lett (2013) 0.96
Zebrafish: an in vivo model for nano EHS studies. Small (2012) 0.96
Aspect ratio plays a role in the hazard potential of CeO2 nanoparticles in mouse lung and zebrafish gastrointestinal tract. ACS Nano (2014) 0.95
Loss of astrocyte polarization upon transient focal brain ischemia as a possible mechanism to counteract early edema formation. Glia (2012) 0.95
Exdpf is a key regulator of exocrine pancreas development controlled by retinoic acid and ptf1a in zebrafish. PLoS Biol (2008) 0.95
Inactivation of mTORC1 in the developing brain causes microcephaly and affects gliogenesis. J Neurosci (2013) 0.94
The Zebrafish Insertion Collection (ZInC): a web based, searchable collection of zebrafish mutations generated by DNA insertion. Nucleic Acids Res (2012) 0.94
Myopathy caused by mammalian target of rapamycin complex 1 (mTORC1) inactivation is not reversed by restoring mitochondrial function. Proc Natl Acad Sci U S A (2011) 0.94
Characterization of zebrafish merlot/chablis as non-mammalian vertebrate models for severe congenital anemia due to protein 4.1 deficiency. Development (2002) 0.93
Zebrafish yolk-specific not really started (nrs) gene is a vertebrate homolog of the Drosophila spinster gene and is essential for embryogenesis. Dev Dyn (2002) 0.93
Etsrp/Etv2 is directly regulated by Foxc1a/b in the zebrafish angioblast. Circ Res (2011) 0.93
Genomic deletion induced by Tol2 transposon excision in zebrafish. Nucleic Acids Res (2012) 0.92
Distinct contributions of angiogenesis and vascular co-option during the initiation of primary microtumors and micrometastases. Carcinogenesis (2011) 0.92
Zebrafish models for dyskeratosis congenita reveal critical roles of p53 activation contributing to hematopoietic defects through RNA processing. PLoS One (2012) 0.92
Zebrafish usp39 mutation leads to rb1 mRNA splicing defect and pituitary lineage expansion. PLoS Genet (2011) 0.92
Apoptosis inhibitors and mini-agrin have additive benefits in congenital muscular dystrophy mice. EMBO Mol Med (2011) 0.91
Identification of vascular and hematopoietic genes downstream of etsrp by deep sequencing in zebrafish. PLoS One (2012) 0.90
EENdb: a database and knowledge base of ZFNs and TALENs for endonuclease engineering. Nucleic Acids Res (2012) 0.90
Converse conformational control of smoothened activity by structurally related small molecules. J Biol Chem (2009) 0.90
MuSK levels differ between adult skeletal muscles and influence postsynaptic plasticity. Eur J Neurosci (2011) 0.90
Pur alpha and Sp8 as opposing regulators of neural gata2 expression. Dev Biol (2004) 0.90
A SNX10/V-ATPase pathway regulates ciliogenesis in vitro and in vivo. Cell Res (2011) 0.90
Male infertility in China: laboratory finding for AZF microdeletions and chromosomal abnormalities in infertile men from Northeastern China. J Assist Reprod Genet (2010) 0.89
Prolactin receptor signaling mediates the osmotic response of embryonic zebrafish lactotrophs. Mol Endocrinol (2005) 0.89
Transdifferentiation of fast skeletal muscle into functional endothelium in vivo by transcription factor Etv2. PLoS Biol (2013) 0.89
Automated phenotype recognition for zebrafish embryo based in vivo high throughput toxicity screening of engineered nano-materials. PLoS One (2012) 0.89
Zebrafish tyrosine hydroxylase 2 gene encodes tryptophan hydroxylase. J Biol Chem (2013) 0.88
Characterization and development of novel small-molecules inhibiting GSK3 and activating Wnt signaling. Mol Biosyst (2009) 0.87
Induction of reversible hemolytic anemia in living zebrafish using a novel small molecule. Comp Biochem Physiol C Toxicol Pharmacol (2004) 0.87
Hedgehog signaling is required for differentiation of endocardial progenitors in zebrafish. Dev Biol (2011) 0.87
Fev regulates hematopoietic stem cell development via ERK signaling. Blood (2013) 0.87
Zebrafish high-throughput screening to study the impact of dissolvable metal oxide nanoparticles on the hatching enzyme, ZHE1. Small (2012) 0.86
Vhnf1 acts downstream of Bmp, Fgf, and RA signals to regulate endocrine beta cell development in zebrafish. Dev Biol (2006) 0.86
The effects of hyperglycemia on adrenal cortex function and steroidogenesis in the zebrafish. Mol Genet Metab (2010) 0.86
Vertebrate MAX-1 is required for vascular patterning in zebrafish. Proc Natl Acad Sci U S A (2006) 0.86