Published in J Biol Chem on May 09, 2007
CDK5RAP2 stimulates microtubule nucleation by the gamma-tubulin ring complex. J Cell Biol (2010) 1.80
The regulation of SIRT2 function by cyclin-dependent kinases affects cell motility. J Cell Biol (2008) 1.63
Interaction of CDK5RAP2 with EB1 to track growing microtubule tips and to regulate microtubule dynamics. Mol Biol Cell (2009) 1.16
A 24-residue peptide (p5), derived from p35, the Cdk5 neuronal activator, specifically inhibits Cdk5-p25 hyperactivity and tau hyperphosphorylation. J Biol Chem (2010) 1.11
Cyclin-dependent kinase 5 regulates the polarized trafficking of neuropeptide-containing dense-core vesicles in Caenorhabditis elegans motor neurons. J Neurosci (2012) 1.05
Phosphorylation of collapsin response mediator protein-2 disrupts neuronal maturation in a model of adult neurogenesis: Implications for neurodegenerative disorders. Mol Neurodegener (2011) 0.83
Microtubule-associated proteins in mesial temporal lobe epilepsy with and without psychiatric comorbidities and their relation with granular cell layer dispersion. Biomed Res Int (2013) 0.81
Dynamic recruitment of CDK5RAP2 to centrosomes requires its association with dynein. PLoS One (2013) 0.81
Actin interaction and regulation of cyclin-dependent kinase 5/p35 complex activity. J Neurochem (2011) 0.81
Calmodulin Binding Proteins and Alzheimer's Disease. J Alzheimers Dis (2015) 0.81
At the Fulcrum in Health and Disease: Cdk5 and the Balancing Acts of Neuronal Structure and Physiology. Brain Disord Ther (2012) 0.79
p35 and Rac1 underlie the neuroprotection and cognitive improvement induced by CDK5 silencing. J Neurochem (2015) 0.78
Caspase-mediated cleavage of C53/LZAP protein causes abnormal microtubule bundling and rupture of the nuclear envelope. Cell Res (2013) 0.78
Soluble alpha-APP (sAPPalpha) regulates CDK5 expression and activity in neurons. PLoS One (2013) 0.78
Phosphorylation of Kif26b promotes its polyubiquitination and subsequent proteasomal degradation during kidney development. PLoS One (2012) 0.77
A Tale of the Good and Bad: Remodeling of the Microtubule Network in the Brain by Cdk5. Mol Neurobiol (2016) 0.76
The interaction of Munc 18 (p67) with the p10 domain of p35 protects in vivo Cdk5/p35 activity from inhibition by TFP5, a peptide derived from p35. Mol Biol Cell (2016) 0.75
The Activators of Cyclin-Dependent Kinase 5 p35 and p39 Are Essential for Oligodendrocyte Maturation, Process Formation, and Myelination. J Neurosci (2016) 0.75
Microtubule Plus-end Tracking of End-binding Protein 1 (EB1) Is Regulated by CDK5 Regulatory Subunit-associated Protein 2. J Biol Chem (2017) 0.75
A second generation human haplotype map of over 3.1 million SNPs. Nature (2007) 85.39
Genome-wide detection and characterization of positive selection in human populations. Nature (2007) 17.27
Extended antiretroviral prophylaxis to reduce breast-milk HIV-1 transmission. N Engl J Med (2008) 8.19
Circulating microRNA: a novel potential biomarker for early diagnosis of acute myocardial infarction in humans. Eur Heart J (2010) 5.04
Genetic ablation of solute carrier family 7a3a leads to hepatic steatosis in zebrafish during fasting. Hepatology (2014) 3.40
Statistical methods for testing effects on "maximum lifespan". Mech Ageing Dev (2004) 3.26
Optimization of sensing and feedback control for vibration/flutter of rotating disk by PZT actuators via air coupled pressure. Sensors (Basel) (2011) 2.84
Up-regulation of mitochondrial activity and acquirement of brown adipose tissue-like property in the white adipose tissue of fsp27 deficient mice. PLoS One (2008) 2.51
The novel neuromodulator hydrogen sulfide: an endogenous peroxynitrite 'scavenger'? J Neurochem (2004) 2.50
Identification of a neuronal Cdk5 activator-binding protein as Cdk5 inhibitor. J Biol Chem (2002) 2.43
Highly multiplexed single-cell analysis of formalin-fixed, paraffin-embedded cancer tissue. Proc Natl Acad Sci U S A (2013) 2.29
Postnatal HIV-1 transmission after cessation of infant extended antiretroviral prophylaxis and effect of maternal highly active antiretroviral therapy. J Infect Dis (2009) 2.26
Rare genetic variation at Zea mays crtRB1 increases beta-carotene in maize grain. Nat Genet (2010) 2.25
Frequency of gastroenteritis and gastroenteritis-associated mortality with early weaning in HIV-1-uninfected children born to HIV-infected women in Malawi. J Acquir Immune Defic Syndr (2010) 2.19
Meta-analysis of Dense Genecentric Association Studies Reveals Common and Uncommon Variants Associated with Height. Am J Hum Genet (2010) 2.15
CDK5RAP2 is a pericentriolar protein that functions in centrosomal attachment of the gamma-tubulin ring complex. Mol Biol Cell (2007) 2.13
Characterization of the bell-shaped vibratory angular rate gyro. Sensors (Basel) (2013) 2.04
Postexposure prophylaxis of breastfeeding HIV-exposed infants with antiretroviral drugs to age 14 weeks: updated efficacy results of the PEPI-Malawi trial. J Acquir Immune Defic Syndr (2011) 1.96
c-Myc rapidly induces acute myeloid leukemia in mice without evidence of lymphoma-associated antiapoptotic mutations. Blood (2005) 1.96
Atypical presentations among Medicare beneficiaries with unstable angina pectoris. Am J Cardiol (2002) 1.92
Mammographic density as a surrogate marker for the effects of hormone therapy on risk of breast cancer. Cancer Epidemiol Biomarkers Prev (2006) 1.91
Inflammatory stress exacerbates hepatic cholesterol accumulation via increasing cholesterol uptake and de novo synthesis. J Gastroenterol Hepatol (2011) 1.86
Disruption of response regulator gene, devR, leads to attenuation in virulence of Mycobacterium tuberculosis. FEMS Microbiol Lett (2004) 1.86
Epigenetic and genetic influences on DNA methylation variation in maize populations. Plant Cell (2013) 1.83
Quasi-ballistic thermal transport from nanoscale interfaces observed using ultrafast coherent soft X-ray beams. Nat Mater (2009) 1.83
CDK5RAP2 stimulates microtubule nucleation by the gamma-tubulin ring complex. J Cell Biol (2010) 1.80
N-Myc downstream-regulated gene 2 (NDRG2) inhibits glioblastoma cell proliferation. Int J Cancer (2003) 1.75
Crystal structure of the swine-origin A (H1N1)-2009 influenza A virus hemagglutinin (HA) reveals similar antigenicity to that of the 1918 pandemic virus. Protein Cell (2010) 1.74
Fertility intentions of HIV-1 infected and uninfected women in Malawi: a longitudinal study. AIDS Behav (2009) 1.73
Response and resistance to MEK inhibition in leukaemias initiated by hyperactive Ras. Nature (2009) 1.72
Protein kinase C delta is required for p47phox phosphorylation and translocation in activated human monocytes. J Immunol (2004) 1.68
Research on bell-shaped vibratory angular rate gyro's character of resonator. Sensors (Basel) (2013) 1.66
Alpha2-chimaerin, cyclin-dependent Kinase 5/p35, and its target collapsin response mediator protein-2 are essential components in semaphorin 3A-induced growth-cone collapse. J Neurosci (2004) 1.66
Cideb regulates diet-induced obesity, liver steatosis, and insulin sensitivity by controlling lipogenesis and fatty acid oxidation. Diabetes (2007) 1.62
Regulation of aurora B expression by the bromodomain protein Brd4. Mol Cell Biol (2009) 1.60
Investigation of the relationships between immune-mediated inhibition of mycobacterial growth and other potential surrogate markers of protective Mycobacterium tuberculosis immunity. J Infect Dis (2002) 1.59
The Burmese python genome reveals the molecular basis for extreme adaptation in snakes. Proc Natl Acad Sci U S A (2013) 1.59
Development of receptor for advanced glycation end products-directed imaging of atherosclerotic plaque in a murine model of spontaneous atherosclerosis. Circ Cardiovasc Imaging (2008) 1.58
Cideb, an ER- and lipid droplet-associated protein, mediates VLDL lipidation and maturation by interacting with apolipoprotein B. Cell Metab (2009) 1.57
Racial differences in thoracic aorta atherosclerosis among ischemic stroke patients. Stroke (2003) 1.53
A theoretical model to predict both horizontal displacement and vertical displacement for electromagnetic induction-based deep displacement sensors. Sensors (Basel) (2011) 1.53
Activation of mammalian target of rapamycin controls the loss of TCRzeta in lupus T cells through HRES-1/Rab4-regulated lysosomal degradation. J Immunol (2009) 1.52
Receptor for advanced-glycation end products: key modulator of myocardial ischemic injury. Circulation (2006) 1.48
Hydrogen sulphide: a novel inhibitor of hypochlorous acid-mediated oxidative damage in the brain? Biochem Biophys Res Commun (2005) 1.48
Acidic preconditioning protects against ischemia-induced brain injury. Neurosci Lett (2012) 1.45
Noc3p, a bHLH protein, plays an integral role in the initiation of DNA replication in budding yeast. Cell (2002) 1.44
Identification of novel factors involved in or regulating initiation of DNA replication by a genome-wide phenotypic screen in Saccharomyces cerevisiae. Cell Cycle (2010) 1.43
Genetic control of heart function and aging in Drosophila. Trends Cardiovasc Med (2007) 1.43
Imaging of receptors for advanced glycation end products in experimental myocardial ischemia and reperfusion injury. JACC Cardiovasc Imaging (2012) 1.40
Retracted Rebamipide plus proton pump inhibitor versus proton pump inhibitor alone in the treatment of endoscopic submucosal dissection-induced gastric ulcer: a meta-analysis of randomized controlled trials. Medicine (Baltimore) (2014) 1.40
Effect of pretreatment of food gluten with prolyl endopeptidase on gluten-induced malabsorption in celiac sprue. Clin Gastroenterol Hepatol (2005) 1.38
Asymmetric somatic stem cells division plays a critical role in cell senescence. Med Hypotheses (2006) 1.38
Specific alleles of bitter receptor genes influence human sensitivity to the bitterness of aloin and saccharin. Curr Biol (2007) 1.37
Role of BCRP 421C>A polymorphism on rosuvastatin pharmacokinetics in healthy Chinese males. Clin Chim Acta (2006) 1.34
The relative distribution of membranous and cytoplasmic met is a prognostic indicator in stage I and II colon cancer. Clin Cancer Res (2008) 1.34
A randomized trial of dietary intervention for breast cancer prevention. Cancer Res (2011) 1.32
d4eBP acts downstream of both dTOR and dFoxo to modulate cardiac functional aging in Drosophila. Aging Cell (2009) 1.31
beta1-Adrenergic receptor polymorphisms influence the response to metoprolol monotherapy in patients with essential hypertension. Clin Pharmacol Ther (2006) 1.31
Nitrogen-doped graphene: beyond single substitution and enhanced molecular sensing. Sci Rep (2012) 1.31
Mitogen-activated protein kinases and retinal ischemia. Invest Ophthalmol Vis Sci (2003) 1.31
A combined proteomics and metabolomics profiling of gastric cardia cancer reveals characteristic dysregulations in glucose metabolism. Mol Cell Proteomics (2010) 1.30
Bromodomain protein Brd4 associated with acetylated chromatin is important for maintenance of higher-order chromatin structure. J Biol Chem (2012) 1.30
Bactericidal activity in whole blood as a potential surrogate marker of immunity after vaccination against tuberculosis. Clin Diagn Lab Immunol (2002) 1.29
RAGE modulates myocardial injury consequent to LAD infarction via impact on JNK and STAT signaling in a murine model. Am J Physiol Heart Circ Physiol (2008) 1.29
Combined use of AFP, CEA, CA125 and CAl9-9 improves the sensitivity for the diagnosis of gastric cancer. BMC Gastroenterol (2013) 1.27
Mutant Ikzf1, KrasG12D, and Notch1 cooperate in T lineage leukemogenesis and modulate responses to targeted agents. Proc Natl Acad Sci U S A (2010) 1.25
Structural and functional analysis of laninamivir and its octanoate prodrug reveals group specific mechanisms for influenza NA inhibition. PLoS Pathog (2011) 1.25
Influenza A virus N5 neuraminidase has an extended 150-cavity. J Virol (2011) 1.25
Do local opinion leaders augment hospital quality improvement efforts? A randomized trial to promote adherence to unstable angina guidelines. Med Care (2003) 1.24
Conserved motif of CDK5RAP2 mediates its localization to centrosomes and the Golgi complex. J Biol Chem (2010) 1.24
Effects of angiotensin II on the pericyte-containing microvasculature of the rat retina. J Physiol (2004) 1.24
Neonatal loss of gamma-aminobutyric acid pathway expression after human perinatal brain injury. J Neurosurg (2006) 1.23
Genetic analysis and characterization of a new maize association mapping panel for quantitative trait loci dissection. Theor Appl Genet (2010) 1.23
The antidepressant sertraline improves the phenotype, promotes neurogenesis and increases BDNF levels in the R6/2 Huntington's disease mouse model. Exp Neurol (2007) 1.22
Abrogation of the Brd4-positive transcription elongation factor B complex by papillomavirus E2 protein contributes to viral oncogene repression. J Virol (2010) 1.22
HER2 interacts with CD44 to up-regulate CXCR4 via epigenetic silencing of microRNA-139 in gastric cancer cells. Gastroenterology (2011) 1.22
Structural basis for recognition of H3K56-acetylated histone H3-H4 by the chaperone Rtt106. Nature (2012) 1.21
Urinary podocyte-associated mRNA profile in various stages of diabetic nephropathy. PLoS One (2011) 1.20
Plasticity of the systemic inflammatory response to acute infection during critical illness: development of the riboleukogram. PLoS One (2008) 1.19
Determination of the Newtonian gravitational constant G with time-of-swing method. Phys Rev Lett (2009) 1.19
Compact instrument for fluorescence image-guided surgery. J Biomed Opt (2010) 1.18
OATP1B1 polymorphism is a major determinant of serum bilirubin level but not associated with rifampicin-mediated bilirubin elevation. Clin Exp Pharmacol Physiol (2007) 1.18
Specific inhibition of cyclin-dependent kinases and cell proliferation by harmine. Biochem Biophys Res Commun (2004) 1.17
Interaction of CDK5RAP2 with EB1 to track growing microtubule tips and to regulate microtubule dynamics. Mol Biol Cell (2009) 1.16
Dendrimer-modified magnetic nanoparticles enhance efficiency of gene delivery system. Cancer Res (2007) 1.16
Cellular mechanism of U18666A-mediated apoptosis in cultured murine cortical neurons: bridging Niemann-Pick disease type C and Alzheimer's disease. Cell Signal (2006) 1.16
Whole-genome screening identifies proteins localized to distinct nuclear bodies. J Cell Biol (2013) 1.15
Longitudinal characterization of brain atrophy of a Huntington's disease mouse model by automated morphological analyses of magnetic resonance images. Neuroimage (2009) 1.15
A review of the biologic effects, clinical efficacy, and safety of silicone elastomer sheeting for hypertrophic and keloid scar treatment and management. Dermatol Surg (2007) 1.15
Anxa2 plays a critical role in enhanced invasiveness of the multidrug resistant human breast cancer cells. J Proteome Res (2009) 1.15
Prolyl endopeptidase-mediated destruction of T cell epitopes in whole gluten: chemical and immunological characterization. J Pharmacol Exp Ther (2004) 1.15
RAGE modulates hypoxia/reoxygenation injury in adult murine cardiomyocytes via JNK and GSK-3beta signaling pathways. PLoS One (2010) 1.15
SZ-685C, a marine anthraquinone, is a potent inducer of apoptosis with anticancer activity by suppression of the Akt/FOXO pathway. Br J Pharmacol (2010) 1.14
Pax3/7BP is a Pax7- and Pax3-binding protein that regulates the proliferation of muscle precursor cells by an epigenetic mechanism. Cell Stem Cell (2012) 1.14
Human papillomavirus type-distribution in cervical cancer in China: the importance of HPV 16 and 18. Cancer Causes Control (2009) 1.14
Expression of costimulatory molecules B7-H1, B7-H4 and Foxp3+ Tregs in gastric cancer and its clinical significance. Int J Clin Oncol (2014) 1.13
In silico characterization of the functional and structural modules of the hemagglutinin protein from the swine-origin influenza virus A (H1N1)-2009. Sci China Life Sci (2010) 1.13
Dominant role of oncogene dosage and absence of tumor suppressor activity in Nras-driven hematopoietic transformation. Cancer Discov (2013) 1.13
Mycobacterium tuberculosis and TLR2 agonists inhibit induction of type I IFN and class I MHC antigen cross processing by TLR9. J Immunol (2010) 1.13