Published in Proc Natl Acad Sci U S A on May 11, 2007
Medium- and short-chain dehydrogenase/reductase gene and protein families : the SDR superfamily: functional and structural diversity within a family of metabolic and regulatory enzymes. Cell Mol Life Sci (2008) 3.07
The SDR (short-chain dehydrogenase/reductase and related enzymes) nomenclature initiative. Chem Biol Interact (2008) 1.77
Stamp2 controls macrophage inflammation through nicotinamide adenine dinucleotide phosphate homeostasis and protects against atherosclerosis. Cell Metab (2012) 0.86
HSCARG regulates NF-kappaB activation by promoting the ubiquitination of RelA or COMMD1. J Biol Chem (2009) 0.84
Negative roles of a novel nitrogen metabolite repression-related gene, TAR1, in laccase production and nitrate utilization by the basidiomycete Cryptococcus neoformans. Appl Environ Microbiol (2009) 0.83
HSCARG, a novel regulator of H2A ubiquitination by downregulating PRC1 ubiquitin E3 ligase activity, is essential for cell proliferation. Nucleic Acids Res (2014) 0.82
The transcription repressor NmrA is subject to proteolysis by three Aspergillus nidulans proteases. Protein Sci (2010) 0.82
The Vein Patterning 1 (VEP1) gene family laterally spread through an ecological network. PLoS One (2011) 0.81
Characterization of an Nmr homolog that modulates GATA factor-mediated nitrogen metabolite repression in Cryptococcus neoformans. PLoS One (2012) 0.80
Glucose-6-Phosphate Dehydrogenase Enhances Antiviral Response through Downregulation of NADPH Sensor HSCARG and Upregulation of NF-κB Signaling. Viruses (2015) 0.77
Crystallization and preliminary X-ray crystallographic analysis of the short-chain dehydrogenase/reductase-type DDB_G0291732 protein from Dictyostelium discoideum. Acta Crystallogr Sect F Struct Biol Cryst Commun (2010) 0.75
Crystallization and preliminary X-ray crystallographic analysis of the NmrA-like DDB_G0286605 protein from the social amoeba Dictyostelium discoideum. Acta Crystallogr Sect F Struct Biol Cryst Commun (2010) 0.75
HSCARG inhibits NADPH oxidase activity through regulation of the expression of p47phox. PLoS One (2013) 0.75
Metabolic control by sirtuins and other enzymes that sense NAD(+), NADH, or their ratio. Biochim Biophys Acta (2017) 0.75
Crystallography & NMR system: A new software suite for macromolecular structure determination. Acta Crystallogr D Biol Crystallogr (1998) 169.28
Improved methods for building protein models in electron density maps and the location of errors in these models. Acta Crystallogr A (1991) 119.63
Calorie restriction extends Saccharomyces cerevisiae lifespan by increasing respiration. Nature (2002) 8.45
SOLVE and RESOLVE: automated structure solution and density modification. Methods Enzymol (2003) 6.96
Nicotinamide and PNC1 govern lifespan extension by calorie restriction in Saccharomyces cerevisiae. Nature (2003) 6.25
Ribbons. Methods Enzymol (1997) 5.83
The CATH Domain Structure Database and related resources Gene3D and DHS provide comprehensive domain family information for genome analysis. Nucleic Acids Res (2005) 5.59
Short-chain dehydrogenases/reductases (SDR). Biochemistry (1995) 5.34
Sirtuins in aging and age-related disease. Cell (2006) 3.95
Regulation of corepressor function by nuclear NADH. Science (2002) 3.83
Short-chain dehydrogenases/reductases (SDR): the 2002 update. Chem Biol Interact (2003) 3.46
Genetics and the specificity of the aging process. Science (2003) 3.20
The new life of a centenarian: signalling functions of NAD(P). Trends Biochem Sci (2004) 2.46
Glucose-6-phosphate dehydrogenase: a "housekeeping" enzyme subject to tissue-specific regulation by hormones, nutrients, and oxidant stress. FASEB J (1994) 2.35
Importance of glucose-6-phosphate dehydrogenase activity for cell growth. J Biol Chem (1998) 2.11
CtBP/BARS: a dual-function protein involved in transcription co-repression and Golgi membrane fission. EMBO J (2003) 1.86
Structure of lactate dehydrogenase at 2-8 A resolution. Nature (1970) 1.78
Argininosuccinate synthetase from the urea cycle to the citrulline-NO cycle. Eur J Biochem (2003) 1.69
NAD+ and NADH in cellular functions and cell death. Front Biosci (2006) 1.46
The application of direct methods and Patterson interpretation to high-resolution native protein data. Acta Crystallogr D Biol Crystallogr (1993) 1.42
The structure of the negative transcriptional regulator NmrA reveals a structural superfamily which includes the short-chain dehydrogenase/reductases. EMBO J (2001) 1.31
Nitric oxide and endoplasmic reticulum stress. Arterioscler Thromb Vasc Biol (2006) 1.30
A method for determination of pyridine nucleotides using a single extract. Anal Biochem (2000) 1.21
Modulation of growth, differentiation and carcinogenesis by dehydroepiandrosterone. Adv Enzyme Regul (1987) 1.18
Argininosuccinate synthase expression is required to maintain nitric oxide production and cell viability in aortic endothelial cells. J Biol Chem (2004) 1.11
Parallel cloning, expression, purification and crystallization of human proteins for structural genomics. Acta Crystallogr D Biol Crystallogr (2002) 1.00
Modulation of the ligand binding properties of the transcription repressor NmrA by GATA-containing DNA and site-directed mutagenesis. Protein Sci (2004) 0.98
On the mechanism of interaction of steroids with human glucose 6-phosphate dehydrogenase. Arch Biochem Biophys (1995) 0.97
Expression of p53 protein in T- and natural killer-cell lymphomas is associated with some clinicopathologic entities but rarely related to p53 mutations. Hum Pathol (2001) 0.92
Mitogenic action of insulin-like growth factor-I on human osteosarcoma MG-63 cells and rat osteoblasts maintained in situ: the role of glucose-6-phosphate dehydrogenase. Bone Miner (1993) 0.89
Binding studies of NADPH to NADP-specific L-glutamate dehydrogenase from Saccharomyces cerevisiae. Eur J Biochem (1975) 0.77
A test of enhancing model accuracy in high-throughput crystallography. J Struct Funct Genomics (2005) 5.96
Oxytocin modulates neural circuitry for social cognition and fear in humans. J Neurosci (2005) 5.42
DATF: a database of Arabidopsis transcription factors. Bioinformatics (2005) 4.34
CXCR1 blockade selectively targets human breast cancer stem cells in vitro and in xenografts. J Clin Invest (2010) 4.22
Structure of the vesicular stomatitis virus nucleoprotein-RNA complex. Science (2006) 3.70
Assuring the quality of next-generation sequencing in clinical laboratory practice. Nat Biotechnol (2012) 3.62
Hyperuricemia induces a primary renal arteriolopathy in rats by a blood pressure-independent mechanism. Am J Physiol Renal Physiol (2002) 3.37
Roles of Aurora kinases in mitosis and tumorigenesis. Mol Cancer Res (2007) 3.20
Crystal structure of the cytoskeleton-associated protein glycine-rich (CAP-Gly) domain. J Biol Chem (2002) 3.01
Know your place: neural processing of social hierarchy in humans. Neuron (2008) 2.92
Spatial and temporal coordination of mitosis by Ran GTPase. Nat Rev Mol Cell Biol (2008) 2.84
China's syphilis epidemic: a systematic review of seroprevalence studies. Sex Transm Dis (2006) 2.23
Fucoidan: structure and bioactivity. Molecules (2008) 2.22
PlantTFDB: a comprehensive plant transcription factor database. Nucleic Acids Res (2007) 2.17
A nonsynonymous SNP in human cytosolic sialidase in a small Asian population results in reduced enzyme activity: potential link with severe adverse reactions to oseltamivir. Cell Res (2007) 2.13
DRTF: a database of rice transcription factors. Bioinformatics (2006) 2.10
Parallel cylindrical water nanochannels in Nafion fuel-cell membranes. Nat Mater (2007) 2.10
Strategic programming of detection and therapy parameters in implantable cardioverter-defibrillators reduces shocks in primary prevention patients: results from the PREPARE (Primary Prevention Parameters Evaluation) study. J Am Coll Cardiol (2008) 2.10
PlantTFDB 2.0: update and improvement of the comprehensive plant transcription factor database. Nucleic Acids Res (2010) 2.09
Extreme high temperatures and hospital admissions for respiratory and cardiovascular diseases. Epidemiology (2009) 2.06
Biventricular implantable cardioverter defibrillators improve survival compared with biventricular pacing alone in patients with severe left ventricular dysfunction. J Cardiovasc Electrophysiol (2004) 2.03
Cutting edge: macrophage inhibition by cyclic AMP (cAMP): differential roles of protein kinase A and exchange protein directly activated by cAMP-1. J Immunol (2005) 2.01
Genome sequences of three agrobacterium biovars help elucidate the evolution of multichromosome genomes in bacteria. J Bacteriol (2009) 1.96
Spatiotemporal manipulation of auxin biosynthesis in cotton ovule epidermal cells enhances fiber yield and quality. Nat Biotechnol (2011) 1.93
Cryo-EM model of the bullet-shaped vesicular stomatitis virus. Science (2010) 1.90
Catechol-O-methyltransferase Val158Met modulation of prefrontal-parietal-striatal brain systems during arithmetic and temporal transformations in working memory. J Neurosci (2007) 1.81
Structure of the vesicular stomatitis virus nucleocapsid in complex with the nucleocapsid-binding domain of the small polymerase cofactor, P. Proc Natl Acad Sci U S A (2009) 1.78
N-Myc downstream-regulated gene 2 (NDRG2) inhibits glioblastoma cell proliferation. Int J Cancer (2003) 1.75
Widespread reductions of cortical thickness in schizophrenia and spectrum disorders and evidence of heritability. Arch Gen Psychiatry (2009) 1.75
SPD--a web-based secreted protein database. Nucleic Acids Res (2005) 1.75
Cyclin B1 is localized to unattached kinetochores and contributes to efficient microtubule attachment and proper chromosome alignment during mitosis. Cell Res (2008) 1.73
Pivotal role of dogs in rabies transmission, China. Emerg Infect Dis (2005) 1.64
Cross-presenting human gammadelta T cells induce robust CD8+ alphabeta T cell responses. Proc Natl Acad Sci U S A (2009) 1.61
Clathrin and phosphatidylinositol-4,5-bisphosphate regulate autophagic lysosome reformation. Nat Cell Biol (2012) 1.60
A DNA replicon system for rapid high-level production of virus-like particles in plants. Biotechnol Bioeng (2009) 1.57
Viral vectors for production of recombinant proteins in plants. J Cell Physiol (2008) 1.55
Dynamic evolution of oryza genomes is revealed by comparative genomic analysis of a genus-wide vertical data set. Plant Cell (2008) 1.55
Epistasis between catechol-O-methyltransferase and type II metabotropic glutamate receptor 3 genes on working memory brain function. Proc Natl Acad Sci U S A (2007) 1.53
Genome-wide identification and evolutionary analysis of the plant specific SBP-box transcription factor family. Gene (2008) 1.49
Molecular mechanisms associated with Angiotensin-converting enzyme-inhibitory peptide activity on vascular extracellular matrix remodeling. Cardiology (2014) 1.45
High-level rapid production of full-size monoclonal antibodies in plants by a single-vector DNA replicon system. Biotechnol Bioeng (2010) 1.44
Comparison of catecholamine response during tilt-table-induced vasovagal syncope in patients <35 to those >65 years of age. Am J Cardiol (2004) 1.43
Genetic variation in AKT1 is linked to dopamine-associated prefrontal cortical structure and function in humans. J Clin Invest (2008) 1.43
An efficient plant viral expression system generating orally immunogenic Norwalk virus-like particles. Vaccine (2008) 1.42
Involvement of Arabidopsis histone deacetylase HDA6 in ABA and salt stress response. J Exp Bot (2010) 1.42
Age-dependence of relative change in circulating epinephrine and norepinephrine concentrations during tilt-induced vasovagal syncope. Heart Rhythm (2012) 1.42
Radio frequency identification enabled wireless sensing for intelligent food logistics. Philos Trans A Math Phys Eng Sci (2014) 1.42
Increased impedance to inspiration ameliorates hemodynamic changes associated with movement to upright posture in orthostatic hypotension: a randomized blinded pilot study. Heart Rhythm (2006) 1.42
Solution structure of a ubiquitin-like domain from tubulin-binding cofactor B. J Biol Chem (2004) 1.40
Targeting of RCC1 to chromosomes is required for proper mitotic spindle assembly in human cells. Curr Biol (2002) 1.40
The Southeast Collaboratory for Structural Genomics: a high-throughput gene to structure factory. Acc Chem Res (2003) 1.39
Altered cortical network dynamics: a potential intermediate phenotype for schizophrenia and association with ZNF804A. Arch Gen Psychiatry (2011) 1.38
The VQ motif protein IKU1 regulates endosperm growth and seed size in Arabidopsis. Plant J (2010) 1.38
Balloon valvuloplasty through the right ventricle: another treatment of pulmonary atresia with intact ventricular septum. Ann Thorac Surg (2013) 1.37
Soil temperature and moisture sensitivities of soil CO2 efflux before and after tillage in a wheat field of Loess Plateau, China. J Environ Sci (China) (2011) 1.36
Crystal structure of the oligomerization domain of the phosphoprotein of vesicular stomatitis virus. J Virol (2006) 1.35
Novel histone demethylase LSD1 inhibitors selectively target cancer cells with pluripotent stem cell properties. Cancer Res (2011) 1.35
High-throughput expression of C. elegans proteins. Genome Res (2004) 1.32
A human-specific de novo protein-coding gene associated with human brain functions. PLoS Comput Biol (2010) 1.31
Role of intermolecular interactions of vesicular stomatitis virus nucleoprotein in RNA encapsidation. J Virol (2007) 1.30
HISTONE DEACETYLASE6 interacts with FLOWERING LOCUS D and regulates flowering in Arabidopsis. Plant Physiol (2011) 1.30
The repression of human differentiation-related gene NDRG2 expression by Myc via Miz-1-dependent interaction with the NDRG2 core promoter. J Biol Chem (2006) 1.27
Promoter methylation, mutation, and genomic deletion are involved in the decreased NDRG2 expression levels in several cancer cell lines. Biochem Biophys Res Commun (2007) 1.27
Two gene determinants are differentially involved in the biogenesis of Fap1 precursors in Streptococcus parasanguis. J Bacteriol (2006) 1.27
Bioprocessing of plant-derived virus-like particles of Norwalk virus capsid protein under current Good Manufacture Practice regulations. Plant Cell Rep (2011) 1.26
Lamin B receptor plays a role in stimulating nuclear envelope production and targeting membrane vesicles to chromatin during nuclear envelope assembly through direct interaction with importin beta. J Cell Sci (2007) 1.26
Structure of the pentameric ligand-gated ion channel ELIC cocrystallized with its competitive antagonist acetylcholine. Nat Commun (2012) 1.26
Risk of syphilis in STI clinic patients: a cross-sectional study of 11,500 cases in Guangxi, China. Sex Transm Infect (2007) 1.25
HDA6 directly interacts with DNA methyltransferase MET1 and maintains transposable element silencing in Arabidopsis. Plant Physiol (2011) 1.24
NDRG2 is a new HIF-1 target gene necessary for hypoxia-induced apoptosis in A549 cells. Cell Physiol Biochem (2008) 1.24
Monoclonal antibody produced in plants efficiently treats West Nile virus infection in mice. Proc Natl Acad Sci U S A (2010) 1.23
Norwalk virus-like particles as vaccines. Expert Rev Vaccines (2010) 1.23
The crystal structure of human adenylate kinase 6: An adenylate kinase localized to the cell nucleus. Proc Natl Acad Sci U S A (2005) 1.23
Efficient agroinfiltration of plants for high-level transient expression of recombinant proteins. J Vis Exp (2013) 1.23
N-Myc downstream-regulated gene 2 is involved in p53-mediated apoptosis. Nucleic Acids Res (2008) 1.22
Clathrin recruits phosphorylated TACC3 to spindle poles for bipolar spindle assembly and chromosome alignment. J Cell Sci (2010) 1.22
Expression of an immunogenic Ebola immune complex in Nicotiana benthamiana. Plant Biotechnol J (2011) 1.21
A nonreplicating subunit vaccine protects mice against lethal Ebola virus challenge. Proc Natl Acad Sci U S A (2011) 1.21
Human Stn1 protects telomere integrity by promoting efficient lagging-strand synthesis at telomeres and mediating C-strand fill-in. Cell Res (2012) 1.20
Production of a novel class of polyreactive pathogenic autoantibodies in BXD2 mice causes glomerulonephritis and arthritis. Arthritis Rheum (2006) 1.20
Distribution study of Chlamydia trachomatis serovars among high-risk women in China performed using PCR-restriction fragment length polymorphism genotyping. J Clin Microbiol (2007) 1.19
An exposed domain in the severe acute respiratory syndrome coronavirus spike protein induces neutralizing antibodies. J Virol (2004) 1.18
Saturated hydraulic conductivity of soils in the Horqin Sand Land of Inner Mongolia, northern China. Environ Monit Assess (2012) 1.18
Poly[[diaqua-hemi-μ(4)-oxalato-μ(2)-oxalato-praseodymium(III)] monohydrate]. Acta Crystallogr Sect E Struct Rep Online (2009) 1.18
Sequential phosphorylation of Nedd1 by Cdk1 and Plk1 is required for targeting of the gammaTuRC to the centrosome. J Cell Sci (2009) 1.17
DNA methylation causes predominant maternal controls of plant embryo growth. PLoS One (2008) 1.15
The dual functions of WLIM1a in cell elongation and secondary wall formation in developing cotton fibers. Plant Cell (2013) 1.15
PCM1 recruits Plk1 to the pericentriolar matrix to promote primary cilia disassembly before mitotic entry. J Cell Sci (2013) 1.15
Direct infusion mass spectrometry or liquid chromatography mass spectrometry for human metabonomics? A serum metabonomic study of kidney cancer. Analyst (2010) 1.15
Structure of the pentameric ligand-gated ion channel GLIC bound with anesthetic ketamine. Structure (2012) 1.14
Effect of cough on heart rate and blood pressure in patients with "cough syncope". Heart Rhythm (2005) 1.14
Progression of chronic liver inflammation and fibrosis driven by activation of c-JUN signaling in Sirt6 mutant mice. J Biol Chem (2012) 1.13
Posttranscriptional control of type I interferon genes by KSRP in the innate immune response against viral infection. Mol Cell Biol (2011) 1.13
OsTDL1A binds to the LRR domain of rice receptor kinase MSP1, and is required to limit sporocyte numbers. Plant J (2008) 1.12
Robust production of virus-like particles and monoclonal antibodies with geminiviral replicon vectors in lettuce. Plant Biotechnol J (2011) 1.12