Published in Biotechnol Bioeng on December 01, 2007
Induction of angiogenesis in tissue-engineered scaffolds designed for bone repair: a combined gene therapy-cell transplantation approach. Proc Natl Acad Sci U S A (2008) 1.25
Polyphosphazene/nano-hydroxyapatite composite microsphere scaffolds for bone tissue engineering. Biomacromolecules (2008) 1.16
2010 Panel on the biomaterials grand challenges. J Biomed Mater Res A (2010) 0.92
Editor's Spotlight/Take 5: Nano-ceramic composite scaffolds for bioreactor-based bone engineering. Clin Orthop Relat Res (2013) 0.89
The influence of side group modification in polyphosphazenes on hydrolysis and cell adhesion of blends with PLGA. Biomaterials (2009) 0.85
In vitro models for the evaluation of angiogenic potential in bone engineering. Acta Pharmacol Sin (2010) 0.81
Fabrication, chemical composition change and phase evolution of biomorphic hydroxyapatite. J Mater Sci Mater Med (2008) 0.80
Preparation of porous 45S5 Bioglass-derived glass-ceramic scaffolds by using rice husk as a porogen additive. J Mater Sci Mater Med (2009) 0.77
International network of cancer genome projects. Nature (2010) 20.35
Sequencing of 50 human exomes reveals adaptation to high altitude. Science (2010) 11.27
Rapid "open-source" engineering of customized zinc-finger nucleases for highly efficient gene modification. Mol Cell (2008) 11.24
Resequencing of 200 human exomes identifies an excess of low-frequency non-synonymous coding variants. Nat Genet (2010) 5.44
Electrospun nanofibrous structure: a novel scaffold for tissue engineering. J Biomed Mater Res (2002) 4.71
Frequent mutations of genes encoding ubiquitin-mediated proteolysis pathway components in clear cell renal cell carcinoma. Nat Genet (2011) 3.66
Direct interaction between Nrf2 and p21(Cip1/WAF1) upregulates the Nrf2-mediated antioxidant response. Mol Cell (2009) 3.50
Using VAAST to identify an X-linked disorder resulting in lethality in male infants due to N-terminal acetyltransferase deficiency. Am J Hum Genet (2011) 3.43
Surgery with molecular fluorescence imaging using activatable cell-penetrating peptides decreases residual cancer and improves survival. Proc Natl Acad Sci U S A (2010) 3.41
Activatable cell penetrating peptides linked to nanoparticles as dual probes for in vivo fluorescence and MR imaging of proteases. Proc Natl Acad Sci U S A (2010) 3.03
A noncanonical mechanism of Nrf2 activation by autophagy deficiency: direct interaction between Keap1 and p62. Mol Cell Biol (2010) 2.93
Complete resequencing of 40 genomes reveals domestication events and genes in silkworm (Bombyx). Science (2009) 2.68
Integrated approach for the identification of human hepatocyte nuclear factor 4alpha target genes using protein binding microarrays. Hepatology (2010) 2.51
Efficient and robust feature extraction by maximum margin criterion. IEEE Trans Neural Netw (2006) 2.32
Roscovitine targets, protein kinases and pyridoxal kinase. J Biol Chem (2005) 2.31
Prevalence of the initiator over the TATA box in human and yeast genes and identification of DNA motifs enriched in human TATA-less core promoters. Gene (2006) 2.31
In vivo characterization of activatable cell penetrating peptides for targeting protease activity in cancer. Integr Biol (Camb) (2009) 2.30
Bone tissue engineering: recent advances and challenges. Crit Rev Biomed Eng (2012) 2.27
Brusatol enhances the efficacy of chemotherapy by inhibiting the Nrf2-mediated defense mechanism. Proc Natl Acad Sci U S A (2011) 2.22
Comprehensive comparison of three commercial human whole-exome capture platforms. Genome Biol (2011) 2.15
MSOAR: a high-throughput ortholog assignment system based on genome rearrangement. J Comput Biol (2007) 2.14
The Mg-chelatase H subunit of Arabidopsis antagonizes a group of WRKY transcription repressors to relieve ABA-responsive genes of inhibition. Plant Cell (2010) 2.13
Genomic segmental polymorphisms in inbred mouse strains. Nat Genet (2004) 1.93
Estimation of allele frequency and association mapping using next-generation sequencing data. BMC Bioinformatics (2011) 1.93
Tissue engineering of bone: material and matrix considerations. J Bone Joint Surg Am (2008) 1.91
Efficient inference of haplotypes from genotypes on a pedigree. J Bioinform Comput Biol (2003) 1.89
Association between variants of PRDM1 and NDP52 and Crohn's disease, based on exome sequencing and functional studies. Gastroenterology (2013) 1.83
Understanding high grade glioma: molecular mechanism, therapy and comprehensive management. Cancer Lett (2013) 1.82
Biomedical Applications of Biodegradable Polymers. J Polym Sci B Polym Phys (2011) 1.80
Computing the minimum recombinant haplotype configuration from incomplete genotype data on a pedigree by integer linear programming. J Comput Biol (2005) 1.78
Systemic in vivo distribution of activatable cell penetrating peptides is superior to that of cell penetrating peptides. Integr Biol (Camb) (2009) 1.78
IsoLasso: a LASSO regression approach to RNA-Seq based transcriptome assembly. J Comput Biol (2011) 1.76
MiR-221 and miR-222 target PUMA to induce cell survival in glioblastoma. Mol Cancer (2010) 1.74
Inference of isoforms from short sequence reads. J Comput Biol (2011) 1.72
Regulation of renal lipid metabolism, lipid accumulation, and glomerulosclerosis in FVBdb/db mice with type 2 diabetes. Diabetes (2005) 1.70
Molecular classification of gliomas based on whole genome gene expression: a systematic report of 225 samples from the Chinese Glioma Cooperative Group. Neuro Oncol (2012) 1.66
Assignment of orthologous genes via genome rearrangement. IEEE/ACM Trans Comput Biol Bioinform (2006) 1.66
A small-molecule inducer of the antioxidant response element. Chem Biol (2010) 1.65
ChemmineR: a compound mining framework for R. Bioinformatics (2008) 1.64
Regulation of renal fatty acid and cholesterol metabolism, inflammation, and fibrosis in Akita and OVE26 mice with type 1 diabetes. Diabetes (2006) 1.64
Crosstalk between Aurora-A and p53: frequent deletion or downregulation of Aurora-A in tumors from p53 null mice. Cancer Cell (2007) 1.59
Natural selection affects multiple aspects of genetic variation at putatively neutral sites across the human genome. PLoS Genet (2011) 1.54
The Wilms tumor gene, Wt1, is critical for mouse spermatogenesis via regulation of sertoli cell polarity and is associated with non-obstructive azoospermia in humans. PLoS Genet (2013) 1.52
Exome sequencing and unrelated findings in the context of complex disease research: ethical and clinical implications. Discov Med (2011) 1.52
Nanobiomaterial applications in orthopedics. J Orthop Res (2007) 1.51
Circulating microRNAs in cancer: origin, function and application. J Exp Clin Cancer Res (2012) 1.50
Real-time in vivo molecular detection of primary tumors and metastases with ratiometric activatable cell-penetrating peptides. Cancer Res (2012) 1.50
Identifying transcription factor binding sites through Markov chain optimization. Bioinformatics (2002) 1.50
High-responsivity graphene/InAs nanowire heterojunction near-infrared photodetectors with distinct photocurrent on/off ratios. Small (2014) 1.49
Electrospun poly(lactic acid-co-glycolic acid) scaffolds for skin tissue engineering. Biomaterials (2008) 1.48
Fiber-based tissue-engineered scaffold for ligament replacement: design considerations and in vitro evaluation. Biomaterials (2005) 1.47
HOTAIR, a cell cycle-associated long noncoding RNA and a strong predictor of survival, is preferentially expressed in classical and mesenchymal glioma. Neuro Oncol (2013) 1.47
Experimental verification of reversed Cherenkov radiation in left-handed metamaterial. Phys Rev Lett (2009) 1.47
Protective effect of nicotine on lipopolysaccharide-induced acute lung injury in mice. Respiration (2010) 1.46
The magnesium-chelatase H subunit binds abscisic acid and functions in abscisic acid signaling: new evidence in Arabidopsis. Plant Physiol (2009) 1.44
Tissue engineered microsphere-based matrices for bone repair: design and evaluation. Biomaterials (2002) 1.44
Analysis of bacterial community composition by oligonucleotide fingerprinting of rRNA genes. Appl Environ Microbiol (2002) 1.41
Bioresorbable nanofiber-based systems for wound healing and drug delivery: optimization of fabrication parameters. J Biomed Mater Res B Appl Biomater (2004) 1.40
A maximum common substructure-based algorithm for searching and predicting drug-like compounds. Bioinformatics (2008) 1.38
Anterior cruciate ligament regeneration using braided biodegradable scaffolds: in vitro optimization studies. Biomaterials (2005) 1.37
A broadly flavivirus cross-neutralizing monoclonal antibody that recognizes a novel epitope within the fusion loop of E protein. PLoS One (2011) 1.36
The chemokine CXCL12 and its receptor CXCR4 promote glioma stem cell-mediated VEGF production and tumour angiogenesis via PI3K/AKT signalling. J Pathol (2011) 1.36
Expression of hypoxia-inducible factor-1 alpha and associated proteins in pancreatic ductal adenocarcinoma and their impact on prognosis. Int J Oncol (2007) 1.35
Transcriptome assembly and isoform expression level estimation from biased RNA-Seq reads. Bioinformatics (2012) 1.34
Whole-genome microRNA expression profiling identifies a 5-microRNA signature as a prognostic biomarker in Chinese patients with primary glioblastoma multiforme. Cancer (2012) 1.33
Uncover disease genes by maximizing information flow in the phenome-interactome network. Bioinformatics (2011) 1.32
Bioreactor-based bone tissue engineering: the influence of dynamic flow on osteoblast phenotypic expression and matrix mineralization. Proc Natl Acad Sci U S A (2004) 1.31
Learning curve of transumbilical single incision laparoscopic cholecystectomy (SILS): a preliminary study of 80 selected patients with benign gallbladder diseases. World J Surg (2011) 1.30
MicroRNA roles in beta-catenin pathway. Mol Cancer (2010) 1.30
Crystal structure of the carnitine transporter and insights into the antiport mechanism. Nat Struct Mol Biol (2010) 1.30
miR-181d: a predictive glioblastoma biomarker that downregulates MGMT expression. Neuro Oncol (2012) 1.29
Diabetic nephropathy is accelerated by farnesoid X receptor deficiency and inhibited by farnesoid X receptor activation in a type 1 diabetes model. Diabetes (2010) 1.29
OligoSpawn: a software tool for the design of overgo probes from large unigene datasets. BMC Bioinformatics (2006) 1.28
Haplotype-based linkage disequilibrium mapping via direct data mining. Bioinformatics (2005) 1.28
MiR-181d acts as a tumor suppressor in glioma by targeting K-ras and Bcl-2. J Cancer Res Clin Oncol (2011) 1.27
Correlation of IDH1 mutation with clinicopathologic factors and prognosis in primary glioblastoma: a report of 118 patients from China. PLoS One (2012) 1.27
Fracture repair with ultrasound: clinical and cell-based evaluation. J Bone Joint Surg Am (2008) 1.27
Short-term and medium-term clinical outcomes of laparoscopic-assisted and open surgery for colorectal cancer: a single center retrospective case-control study. BMC Gastroenterol (2011) 1.25
IL28B genetic variation is associated with spontaneous clearance of hepatitis C virus, treatment response, serum IL-28B levels in Chinese population. PLoS One (2012) 1.25
Induction of angiogenesis in tissue-engineered scaffolds designed for bone repair: a combined gene therapy-cell transplantation approach. Proc Natl Acad Sci U S A (2008) 1.25
VHL regulates the effects of miR-23b on glioma survival and invasion via suppression of HIF-1α/VEGF and β-catenin/Tcf-4 signaling. Neuro Oncol (2012) 1.24
Extensive X-linked adaptive evolution in central chimpanzees. Proc Natl Acad Sci U S A (2012) 1.23
Confirmation by exome sequencing of the pathogenic role of NCSTN mutations in acne inversa (hidradenitis suppurativa). J Invest Dermatol (2011) 1.23
Manipulating electromagnetic wave polarizations by anisotropic metamaterials. Phys Rev Lett (2007) 1.22
Computational prediction of operons in Synechococcus sp. WH8102. Genome Inform (2004) 1.22
MiR-410 regulates MET to influence the proliferation and invasion of glioma. Int J Biochem Cell Biol (2012) 1.22
Nrf2 promotes neuronal cell differentiation. Free Radic Biol Med (2009) 1.22
Development of novel tissue engineering scaffolds via electrospinning. Expert Opin Biol Ther (2004) 1.20
Plasma IGFBP-2 levels predict clinical outcomes of patients with high-grade gliomas. Neuro Oncol (2009) 1.20
Computational prediction of type III secreted proteins from gram-negative bacteria. BMC Bioinformatics (2010) 1.19
Inhibition of STAT3 activity with AG490 decreases the invasion of human pancreatic cancer cells in vitro. Cancer Sci (2006) 1.18
Crystal structure of the neurotrophin-3 and p75NTR symmetrical complex. Nature (2008) 1.18