Published in J Mol Cell Cardiol on April 14, 2007
Dysregulation of microRNAs after myocardial infarction reveals a role of miR-29 in cardiac fibrosis. Proc Natl Acad Sci U S A (2008) 9.86
miR-21: a small multi-faceted RNA. J Cell Mol Med (2009) 5.59
MicroRNAs: powerful new regulators of heart disease and provocative therapeutic targets. J Clin Invest (2007) 4.76
MicroRNA-208a is a regulator of cardiac hypertrophy and conduction in mice. J Clin Invest (2009) 4.39
Targeted deletion of Dicer in the heart leads to dilated cardiomyopathy and heart failure. Proc Natl Acad Sci U S A (2008) 4.00
MicroRNAs add a new dimension to cardiovascular disease. Circulation (2010) 3.64
Inhibition of miR-25 improves cardiac contractility in the failing heart. Nature (2014) 3.31
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MicroRNA-21 targets Sprouty2 and promotes cellular outgrowths. Mol Biol Cell (2008) 3.10
MicroRNA regulatory networks in cardiovascular development. Dev Cell (2010) 3.09
Stress-dependent cardiac remodeling occurs in the absence of microRNA-21 in mice. J Clin Invest (2010) 3.04
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Reciprocal regulation of myocardial microRNAs and messenger RNA in human cardiomyopathy and reversal of the microRNA signature by biomechanical support. Circulation (2009) 2.70
MicroRNA-206: the skeletal muscle-specific myomiR. Biochim Biophys Acta (2008) 2.64
microRNA-1 and microRNA-206 regulate skeletal muscle satellite cell proliferation and differentiation by repressing Pax7. J Cell Biol (2010) 2.57
MicroRNAs and cardiac pathology. Nat Rev Cardiol (2009) 2.50
MicroRNA-133a protects against myocardial fibrosis and modulates electrical repolarization without affecting hypertrophy in pressure-overloaded adult hearts. Circ Res (2009) 2.40
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MicroRNA-21 is a downstream effector of AKT that mediates its antiapoptotic effects via suppression of Fas ligand. J Biol Chem (2010) 1.94
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MicroRNA-21 in cardiovascular disease. J Cardiovasc Transl Res (2010) 1.90
MiR-21 is induced in endothelial cells by shear stress and modulates apoptosis and eNOS activity. Biochem Biophys Res Commun (2010) 1.76
Myocardial AKT: the omnipresent nexus. Physiol Rev (2011) 1.76
microRNAs and muscle disorders. J Cell Sci (2009) 1.73
mir-17-92 cluster is required for and sufficient to induce cardiomyocyte proliferation in postnatal and adult hearts. Circ Res (2013) 1.72
MicroRNA-21 orchestrates high glucose-induced signals to TOR complex 1, resulting in renal cell pathology in diabetes. J Biol Chem (2011) 1.70
Clinical, molecular, and genomic changes in response to a left ventricular assist device. J Am Coll Cardiol (2011) 1.69
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Role of microRNAs in the reperfused myocardium towards post-infarct remodelling. Cardiovasc Res (2011) 1.47
Acceleration of muscle regeneration by local injection of muscle-specific microRNAs in rat skeletal muscle injury model. J Cell Mol Med (2010) 1.44
MicroRNAs and cardiovascular diseases. FEBS J (2011) 1.41
MicroRNA-22 regulates cardiac hypertrophy and remodeling in response to stress. Circ Res (2013) 1.39
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Differential expression of microRNAs in different disease states. Circ Res (2012) 1.30
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Role of specific microRNAs for endothelial function and angiogenesis. Biochem Biophys Res Commun (2009) 1.21
Epitranscriptional orchestration of genetic reprogramming is an emergent property of stress-regulated cardiac microRNAs. Proc Natl Acad Sci U S A (2012) 1.20
Essential amino acids increase microRNA-499, -208b, and -23a and downregulate myostatin and myocyte enhancer factor 2C mRNA expression in human skeletal muscle. J Nutr (2009) 1.20
Circulating microRNAs and aerobic fitness--the HUNT-Study. PLoS One (2013) 1.20
MicroRNA 320a functions as a novel endogenous modulator of aquaporins 1 and 4 as well as a potential therapeutic target in cerebral ischemia. J Biol Chem (2010) 1.19
microRNAs in cardiovascular development. J Mol Cell Cardiol (2012) 1.17
miR-155 inhibits expression of the MEF2A protein to repress skeletal muscle differentiation. J Biol Chem (2011) 1.13
MicroRNAs are involved in homocysteine-induced cardiac remodeling. Cell Biochem Biophys (2009) 1.11
MicroRNA-27a regulates beta cardiac myosin heavy chain gene expression by targeting thyroid hormone receptor beta1 in neonatal rat ventricular myocytes. Mol Cell Biol (2010) 1.09
MicroRNA in Aging: From Discovery to Biology. Curr Genomics (2012) 1.08
NFATc4 is negatively regulated in miR-133a-mediated cardiomyocyte hypertrophic repression. Am J Physiol Heart Circ Physiol (2010) 1.07
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MicroRNAs: a novel class of potential therapeutic targets for cardiovascular diseases. Acta Pharmacol Sin (2009) 1.05
Loss of microRNAs in neural crest leads to cardiovascular syndromes resembling human congenital heart defects. Arterioscler Thromb Vasc Biol (2010) 1.05
Discovering ligands for a microRNA precursor with peptoid microarrays. Nucleic Acids Res (2009) 1.04
MicroRNAs in cardiomyocyte development. Wiley Interdiscip Rev Syst Biol Med (2011) 1.04
A deep sequencing approach to uncover the miRNOME in the human heart. PLoS One (2013) 1.04
Loss of MicroRNA-155 protects the heart from pathological cardiac hypertrophy. Circ Res (2014) 1.02
miRNAs at the heart of the matter. J Mol Med (Berl) (2008) 1.01
Endocrine disruptor regulation of microRNA expression in breast carcinoma cells. PLoS One (2012) 1.00
Repression of miR-142 by p300 and MAPK is required for survival signalling via gp130 during adaptive hypertrophy. EMBO Mol Med (2012) 0.99
Trisomy-21 gene dosage over-expression of miRNAs results in the haploinsufficiency of specific target proteins. RNA Biol (2010) 0.98
Reduced cystathionine γ-lyase and increased miR-21 expression are associated with increased vascular resistance in growth-restricted pregnancies: hydrogen sulfide as a placental vasodilator. Am J Pathol (2013) 0.98
An analysis of the global expression of microRNAs in an experimental model of physiological left ventricular hypertrophy. PLoS One (2014) 0.97
MicroRNA 21 inhibits left ventricular remodeling in the early phase of rat model with ischemia-reperfusion injury by suppressing cell apoptosis. Int J Med Sci (2012) 0.97
Developmental microRNA expression profiling of murine embryonic orofacial tissue. Birth Defects Res A Clin Mol Teratol (2010) 0.96
Altered microRNA and gene expression in the follicular fluid of women with polycystic ovary syndrome. J Assist Reprod Genet (2014) 0.95
Global microRNA profiling of the mouse ventricles during development of severe hypertrophic cardiomyopathy and heart failure. PLoS One (2012) 0.95
TGFβ-stimulated microRNA-21 utilizes PTEN to orchestrate AKT/mTORC1 signaling for mesangial cell hypertrophy and matrix expansion. PLoS One (2012) 0.94
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The magic and mystery of miR-21. J Clin Invest (2010) 0.94
Regulation of cardiac microRNAs by serum response factor. J Biomed Sci (2011) 0.93
β-adrenoceptor regulates miRNA expression in rat heart. Med Sci Monit (2012) 0.93
Transgenic overexpression of miR-133a in skeletal muscle. BMC Musculoskelet Disord (2011) 0.93
Emerging role of microRNAs in diagnosis and treatment of various diseases including ovarian cancer. J Ovarian Res (2009) 0.92
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Swimming exercise training-induced left ventricular hypertrophy involves microRNAs and synergistic regulation of the PI3K/AKT/mTOR signaling pathway. Eur J Appl Physiol (2013) 0.91
Microribonucleic acid-21 increases aldosterone secretion and proliferation in H295R human adrenocortical cells. Endocrinology (2008) 0.90
miR-21 promotes fibrogenic epithelial-to-mesenchymal transition of epicardial mesothelial cells involving Programmed Cell Death 4 and Sprouty-1. PLoS One (2013) 0.90
Entrapment neuropathy results in different microRNA expression patterns from denervation injury in rats. BMC Musculoskelet Disord (2010) 0.90
The expression and potential regulatory function of microRNAs in the pathogenesis of leiomyoma. Semin Reprod Med (2008) 0.90
Small engine, big power: microRNAs as regulators of cardiac diseases and regeneration. Int J Mol Sci (2014) 0.89
Identification and comparative analyses of myocardial miRNAs involved in the fetal response to maternal obesity. Physiol Genomics (2013) 0.89
Combined deep microRNA and mRNA sequencing identifies protective transcriptomal signature of enhanced PI3Kα signaling in cardiac hypertrophy. J Mol Cell Cardiol (2012) 0.87
Restriction of big hearts by a small RNA. Circ Res (2011) 0.87
MicroRNA regulation and role in stem cell maintenance, cardiac differentiation and hypertrophy. Curr Mol Med (2013) 0.87
MicroRNAs as newer therapeutic targets: A big hope from a tiny player. J Pharmacol Pharmacother (2012) 0.87
Developmental expression and cardiac transcriptional regulation of Myh7b, a third myosin heavy chain in the vertebrate heart. Cytoskeleton (Hoboken) (2012) 0.86
Conditions that promote primary human skeletal myoblast culture and muscle differentiation in vitro. Am J Physiol Cell Physiol (2013) 0.86
MicroRNA profiling in ischemic injury of the gracilis muscle in rats. BMC Musculoskelet Disord (2010) 0.85
Dynamic gene expression patterns in animal models of early and late heart failure reveal biphasic-bidirectional transcriptional activation of signaling pathways. Physiol Genomics (2014) 0.85
miR-92a inhibits vascular smooth muscle cell apoptosis: role of the MKK4-JNK pathway. Apoptosis (2014) 0.84
MicroRNA involvement in immune activation during heart failure. Cardiovasc Drugs Ther (2011) 0.84
Nitric oxide: perspectives and emerging studies of a well known cytotoxin. Int J Mol Sci (2010) 0.84
MicroRNAs in cardiac development and remodeling. Pediatr Cardiol (2010) 0.84
Common microRNA signatures in cardiac hypertrophic and atrophic remodeling induced by changes in hemodynamic load. PLoS One (2010) 0.84
Application of microRNA in cardiac and skeletal muscle disease gene therapy. Methods Mol Biol (2011) 0.84
MmPalateMiRNA, an R package compendium illustrating analysis of miRNA microarray data. Source Code Biol Med (2013) 0.84
MicroRNAs in skeletogenesis. Front Biosci (Landmark Ed) (2009) 0.84
MicroRNAs in cardiac regeneration and cardiovascular disease. Sci China Life Sci (2013) 0.84
Emerging role of microRNA-21 in cancer. Biomed Rep (2016) 0.84
miR-22 in cardiac remodeling and disease. Trends Cardiovasc Med (2014) 0.83
MicroRNAs: genomics, biogenesis, mechanism, and function. Cell (2004) 198.59
Asymmetry in the assembly of the RNAi enzyme complex. Cell (2003) 22.18
Functional siRNAs and miRNAs exhibit strand bias. Cell (2003) 19.15
MicroRNA-21 is an antiapoptotic factor in human glioblastoma cells. Cancer Res (2005) 18.58
Serum response factor regulates a muscle-specific microRNA that targets Hand2 during cardiogenesis. Nature (2005) 17.17
The role of microRNA-1 and microRNA-133 in skeletal muscle proliferation and differentiation. Nat Genet (2005) 17.07
Regulation by let-7 and lin-4 miRNAs results in target mRNA degradation. Cell (2005) 15.26
Extensive post-transcriptional regulation of microRNAs and its implications for cancer. Genes Dev (2006) 11.04
A signature pattern of stress-responsive microRNAs that can evoke cardiac hypertrophy and heart failure. Proc Natl Acad Sci U S A (2006) 10.09
Antisense inhibition of human miRNAs and indications for an involvement of miRNA in cell growth and apoptosis. Nucleic Acids Res (2005) 9.80
A custom microarray platform for analysis of microRNA gene expression. Nat Methods (2004) 9.44
MicroRNAs play an essential role in the development of cardiac hypertrophy. Circ Res (2007) 5.65
Segregation of atrial-specific and inducible expression of an atrial natriuretic factor transgene in an in vivo murine model of cardiac hypertrophy. Proc Natl Acad Sci U S A (1991) 5.60
MicroRNAs regulate the expression of the alternative splicing factor nPTB during muscle development. Genes Dev (2007) 4.01
Activated MEK5 induces serial assembly of sarcomeres and eccentric cardiac hypertrophy. EMBO J (2001) 2.19
Myocardin induces cardiomyocyte hypertrophy. Circ Res (2006) 1.74
A microRNA polycistron as a potential human oncogene. Nature (2005) 40.21
Argonaute2 is the catalytic engine of mammalian RNAi. Science (2004) 22.86
The role of microRNA-1 and microRNA-133 in skeletal muscle proliferation and differentiation. Nat Genet (2005) 17.07
MicroRNAs regulate brain morphogenesis in zebrafish. Science (2005) 11.16
Extensive post-transcriptional regulation of microRNAs and its implications for cancer. Genes Dev (2006) 11.04
A custom microarray platform for analysis of microRNA gene expression. Nat Methods (2004) 9.44
Lin-28 interaction with the Let-7 precursor loop mediates regulated microRNA processing. RNA (2008) 6.86
Fragile X-related protein and VIG associate with the RNA interference machinery. Genes Dev (2002) 6.43
Myocardin and ternary complex factors compete for SRF to control smooth muscle gene expression. Nature (2004) 4.76
Direct regulation of an oncogenic micro-RNA cluster by E2F transcription factors. J Biol Chem (2006) 4.57
Ipr1 gene mediates innate immunity to tuberculosis. Nature (2005) 4.53
MicroRNA-208a is a regulator of cardiac hypertrophy and conduction in mice. J Clin Invest (2009) 4.39
Myocardin is a master regulator of smooth muscle gene expression. Proc Natl Acad Sci U S A (2003) 4.35
Transgenic over-expression of the microRNA miR-17-92 cluster promotes proliferation and inhibits differentiation of lung epithelial progenitor cells. Dev Biol (2007) 4.16
Targeted deletion of Dicer in the heart leads to dilated cardiomyopathy and heart failure. Proc Natl Acad Sci U S A (2008) 4.00
Myocardin is a key regulator of CArG-dependent transcription of multiple smooth muscle marker genes. Circ Res (2003) 3.99
A micrococcal nuclease homologue in RNAi effector complexes. Nature (2003) 3.67
The serum response factor coactivator myocardin is required for vascular smooth muscle development. Proc Natl Acad Sci U S A (2003) 3.40
microRNA expression in the prefrontal cortex of individuals with schizophrenia and schizoaffective disorder. Genome Biol (2007) 3.26
Raf kinase inhibitory protein suppresses a metastasis signalling cascade involving LIN28 and let-7. EMBO J (2009) 3.11
Atrogin-1/muscle atrophy F-box inhibits calcineurin-dependent cardiac hypertrophy by participating in an SCF ubiquitin ligase complex. J Clin Invest (2004) 3.09
Prevention of endotoxin-induced systemic response by bone marrow-derived mesenchymal stem cells in mice. Am J Physiol Lung Cell Mol Physiol (2007) 2.88
Polymorphisms in interleukin-15 gene on chromosome 4q31.2 are associated with psoriasis vulgaris in Chinese population. J Invest Dermatol (2007) 2.59
microRNA-1 and microRNA-206 regulate skeletal muscle satellite cell proliferation and differentiation by repressing Pax7. J Cell Biol (2010) 2.57
Modulation of cardiac growth and development by HOP, an unusual homeodomain protein. Cell (2002) 2.53
Increased circulating endothelial progenitor cells are associated with survival in acute lung injury. Am J Respir Crit Care Med (2005) 2.33
Distinguishing arrhythmogenic right ventricular cardiomyopathy/dysplasia-associated mutations from background genetic noise. J Am Coll Cardiol (2011) 2.31
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Modulation of smooth muscle gene expression by association of histone acetyltransferases and deacetylases with myocardin. Mol Cell Biol (2005) 2.30
The MEF2D transcription factor mediates stress-dependent cardiac remodeling in mice. J Clin Invest (2008) 2.24
Planetary biology--paleontological, geological, and molecular histories of life. Science (2002) 2.21
miR-93, miR-98, and miR-197 regulate expression of tumor suppressor gene FUS1. Mol Cancer Res (2009) 2.11
MicroRNAs as tumor suppressors. Nat Genet (2007) 2.09
Flagellin treatment protects against chemicals, bacteria, viruses, and radiation. J Immunol (2008) 2.07
Emerging paradigms of regulated microRNA processing. Genes Dev (2010) 2.06
Muscle ring finger 1, but not muscle ring finger 2, regulates cardiac hypertrophy in vivo. Circ Res (2007) 2.05
Control of virus reactivation arrests pulmonary herpesvirus-induced fibrosis in IFN-gamma receptor-deficient mice. Am J Respir Crit Care Med (2007) 2.05
Targeted deletion of metalloproteinase 9 attenuates experimental colitis in mice: central role of epithelial-derived MMP. Gastroenterology (2005) 2.03
Loss of mXinalpha, an intercalated disk protein, results in cardiac hypertrophy and cardiomyopathy with conduction defects. Am J Physiol Heart Circ Physiol (2007) 1.99
A myocardium tropic adeno-associated virus (AAV) evolved by DNA shuffling and in vivo selection. Proc Natl Acad Sci U S A (2009) 1.85
MicroRNAs in skeletal and cardiac muscle development. DNA Cell Biol (2007) 1.81
A prospective randomized study of clinical assessment versus computed tomography for the diagnosis of acute appendicitis. Surg Infect (Larchmt) (2003) 1.77
Activation of alveolar macrophages via the alternative pathway in herpesvirus-induced lung fibrosis. Am J Respir Cell Mol Biol (2006) 1.75
Inferring the palaeoenvironment of ancient bacteria on the basis of resurrected proteins. Nature (2003) 1.75
Myocardin induces cardiomyocyte hypertrophy. Circ Res (2006) 1.74
microRNAs and muscle disorders. J Cell Sci (2009) 1.73
mir-17-92 cluster is required for and sufficient to induce cardiomyocyte proliferation in postnatal and adult hearts. Circ Res (2013) 1.72
Taking microRNAs to heart. Trends Mol Med (2008) 1.69
Stem cells and cell therapies in lung biology and lung diseases. Proc Am Thorac Soc (2011) 1.66
miR-17~92 cooperates with RB pathway mutations to promote retinoblastoma. Genes Dev (2011) 1.66
Fgf-dependent depletion of microRNA-133 promotes appendage regeneration in zebrafish. Genes Dev (2008) 1.64
Role of the SDF-1/CXCR4 axis in the pathogenesis of lung injury and fibrosis. Am J Respir Cell Mol Biol (2007) 1.61
Micro-RNA-155 inhibits IFN-gamma signaling in CD4+ T cells. Eur J Immunol (2010) 1.59
Anti-inflammatory effects of mesenchymal stem cells: novel concept for future therapies. Expert Opin Biol Ther (2008) 1.59
Lung infection with gamma-herpesvirus induces progressive pulmonary fibrosis in Th2-biased mice. Am J Physiol Lung Cell Mol Physiol (2005) 1.56
Muscling through the microRNA world. Exp Biol Med (Maywood) (2008) 1.55
Cardiac response to pressure overload in 129S1/SvImJ and C57BL/6J mice: temporal- and background-dependent development of concentric left ventricular hypertrophy. Am J Physiol Heart Circ Physiol (2006) 1.52
Deep sequencing of microRNA precursors reveals extensive 3' end modification. RNA (2011) 1.49
miR-29b is activated during neuronal maturation and targets BH3-only genes to restrict apoptosis. Genes Dev (2011) 1.48
Wnt1/βcatenin injury response activates the epicardium and cardiac fibroblasts to promote cardiac repair. EMBO J (2011) 1.47
A putative role for microRNA-205 in mammary epithelial cell progenitors. J Cell Sci (2010) 1.47
CIP, a cardiac Isl1-interacting protein, represses cardiomyocyte hypertrophy. Circ Res (2012) 1.46
MicroRNA-22 regulates cardiac hypertrophy and remodeling in response to stress. Circ Res (2013) 1.39
Rib fractures and death from deletion of osteoblast βcatenin in adult mice is rescued by corticosteroids. PLoS One (2013) 1.39
Myocardin is sufficient and necessary for cardiac gene expression in Xenopus. Development (2005) 1.37
Myocardin is a bifunctional switch for smooth versus skeletal muscle differentiation. Proc Natl Acad Sci U S A (2007) 1.35
Myocardin inhibits cellular proliferation by inhibiting NF-kappaB(p65)-dependent cell cycle progression. Proc Natl Acad Sci U S A (2008) 1.35
Myocyte-restricted focal adhesion kinase deletion attenuates pressure overload-induced hypertrophy. Circ Res (2006) 1.34
Body mass index is associated with reduced exhaled nitric oxide and higher exhaled 8-isoprostanes in asthmatics. Respir Res (2007) 1.33
Muscle ring finger 1 mediates cardiac atrophy in vivo. Am J Physiol Heart Circ Physiol (2009) 1.33
Cysteine redox potential determines pro-inflammatory IL-1beta levels. PLoS One (2009) 1.30
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