Published in Genome Inform on January 01, 2006
An abundance of ubiquitously expressed genes revealed by tissue transcriptome sequence data. PLoS Comput Biol (2009) 7.47
UniHI: an entry gate to the human protein interactome. Nucleic Acids Res (2006) 2.45
Network integration and graph analysis in mammalian molecular systems biology. IET Syst Biol (2008) 1.03
Modelling the yeast interactome. Sci Rep (2014) 0.78
A human protein-protein interaction network: a resource for annotating the proteome. Cell (2005) 18.97
An empirical framework for binary interactome mapping. Nat Methods (2008) 6.59
EGCG redirects amyloidogenic polypeptides into unstructured, off-pathway oligomers. Nat Struct Mol Biol (2008) 5.32
Biological profiling of gene groups utilizing Gene Ontology. Genome Inform (2005) 4.10
Differential effects of PER2 phosphorylation: molecular basis for the human familial advanced sleep phase syndrome (FASPS). Genes Dev (2006) 3.78
Tight regulation of unstructured proteins: from transcript synthesis to protein degradation. Science (2008) 3.48
A protein interaction network links GIT1, an enhancer of huntingtin aggregation, to Huntington's disease. Mol Cell (2004) 3.26
The hunt for huntingtin function: interaction partners tell many different stories. Trends Biochem Sci (2003) 3.15
Spontaneous synchronization of coupled circadian oscillators. Biophys J (2005) 2.55
EGCG remodels mature alpha-synuclein and amyloid-beta fibrils and reduces cellular toxicity. Proc Natl Acad Sci U S A (2010) 2.48
UniHI: an entry gate to the human protein interactome. Nucleic Acids Res (2006) 2.45
Mathematical modeling identifies inhibitors of apoptosis as mediators of positive feedback and bistability. PLoS Comput Biol (2006) 2.30
Genome-wide expression dynamics of a marine virus and host reveal features of co-evolution. Nature (2007) 2.27
HIPPIE: Integrating protein interaction networks with experiment based quality scores. PLoS One (2012) 2.17
Plant nitric oxide synthase: a never-ending story? Trends Plant Sci (2006) 2.12
Nuclear oncoprotein prothymosin alpha is a partner of Keap1: implications for expression of oxidative stress-protecting genes. Mol Cell Biol (2005) 2.10
Molecular insights into human daily behavior. Proc Natl Acad Sci U S A (2008) 2.03
HDAC4 reduction: a novel therapeutic strategy to target cytoplasmic huntingtin and ameliorate neurodegeneration. PLoS Biol (2013) 1.96
A directed protein interaction network for investigating intracellular signal transduction. Sci Signal (2011) 1.95
A potent small molecule inhibits polyglutamine aggregation in Huntington's disease neurons and suppresses neurodegeneration in vivo. Proc Natl Acad Sci U S A (2005) 1.88
Coupling governs entrainment range of circadian clocks. Mol Syst Biol (2010) 1.85
Effects of sequestration on signal transduction cascades. FEBS J (2006) 1.84
Identification of cyanobacterial non-coding RNAs by comparative genome analysis. Genome Biol (2005) 1.82
Proteome analysis of soluble nuclear proteins reveals that HMGB1/2 suppress genotoxic stress in polyglutamine diseases. Nat Cell Biol (2007) 1.81
Comparison of human protein-protein interaction maps. Bioinformatics (2007) 1.79
Green tea (-)-epigallocatechin-gallate modulates early events in huntingtin misfolding and reduces toxicity in Huntington's disease models. Hum Mol Genet (2006) 1.77
The challenge of regulation in a minimal photoautotroph: non-coding RNAs in Prochlorococcus. PLoS Genet (2008) 1.74
Synchronization-induced rhythmicity of circadian oscillators in the suprachiasmatic nucleus. PLoS Comput Biol (2007) 1.71
Pathological consequences of VCP mutations on human striated muscle. Brain (2006) 1.68
Regulation of clock-controlled genes in mammals. PLoS One (2009) 1.65
Beta-TrCP1-mediated degradation of PERIOD2 is essential for circadian dynamics. J Biol Rhythms (2007) 1.64
Small-molecule conversion of toxic oligomers to nontoxic β-sheet-rich amyloid fibrils. Nat Chem Biol (2011) 1.54
Choreography of the transcriptome, photophysiology, and cell cycle of a minimal photoautotroph, prochlorococcus. PLoS One (2009) 1.51
Aggregation of polyQ-extended proteins is promoted by interaction with their natural coiled-coil partners. Bioessays (2013) 1.48
How robust are switches in intracellular signaling cascades? J Theor Biol (2003) 1.47
Functioning and robustness of a bacterial circadian clock. Mol Syst Biol (2007) 1.46
Modeling feedback loops of the Mammalian circadian oscillator. Biophys J (2004) 1.45
An arginine/lysine-rich motif is crucial for VCP/p97-mediated modulation of ataxin-3 fibrillogenesis. EMBO J (2006) 1.45
The value of high quality protein-protein interaction networks for systems biology. Curr Opin Chem Biol (2006) 1.44
Comparison of biomechanical modeling of register transitions and voice instabilities with excised larynx experiments. J Acoust Soc Am (2007) 1.43
Recurrent design patterns in the feedback regulation of the mammalian signalling network. Mol Syst Biol (2008) 1.41
Evolution and function of CAG/polyglutamine repeats in protein-protein interaction networks. Nucleic Acids Res (2012) 1.38
Modelling transcriptional feedback loops: the role of Gro/TLE1 in Hes1 oscillations. Philos Trans A Math Phys Eng Sci (2006) 1.36
Polyglutamine fibrillogenesis: the pathway unfolds. Proc Natl Acad Sci U S A (2002) 1.32
Identification of benzothiazoles as potential polyglutamine aggregation inhibitors of Huntington's disease by using an automated filter retardation assay. Proc Natl Acad Sci U S A (2002) 1.30
A molecular pathogenesis for transcription factor associated poly-alanine tract expansions. Hum Mol Genet (2004) 1.29
UniHI 4: new tools for query, analysis and visualization of the human protein-protein interactome. Nucleic Acids Res (2008) 1.28
Inferring combinatorial regulation of transcription in silico. Nucleic Acids Res (2005) 1.26
Small RNAs establish delays and temporal thresholds in gene expression. Biophys J (2008) 1.24
HIF1α modulates cell fate reprogramming through early glycolytic shift and upregulation of PDK1-3 and PKM2. Stem Cells (2014) 1.23
Bifurcation analysis of the regulatory modules of the mammalian G1/S transition. Bioinformatics (2004) 1.22
Ataxin-2 and huntingtin interact with endophilin-A complexes to function in plastin-associated pathways. Hum Mol Genet (2005) 1.21
Are we overestimating the number of cell-cycling genes? The impact of background models on time-series analysis. Bioinformatics (2008) 1.20
Tuning the mammalian circadian clock: robust synergy of two loops. PLoS Comput Biol (2011) 1.18
Experimental and computational analysis of transcriptional start sites in the cyanobacterium Prochlorococcus MED4. Nucleic Acids Res (2003) 1.18
Nonlinear analysis of irregular animal vocalizations. J Acoust Soc Am (2002) 1.17
Structural properties of EGCG-induced, nontoxic Alzheimer's disease Aβ oligomers. J Mol Biol (2012) 1.16
A fluorescent two-hybrid assay for direct visualization of protein interactions in living cells. Mol Cell Proteomics (2008) 1.15
Quantification of circadian rhythms in single cells. PLoS Comput Biol (2009) 1.14
Measuring similarities between transcription factor binding sites. BMC Bioinformatics (2005) 1.13
Mutant huntingtin promotes the fibrillogenesis of wild-type huntingtin: a potential mechanism for loss of huntingtin function in Huntington's disease. J Biol Chem (2003) 1.13
Competing docking interactions can bring about bistability in the MAPK cascade. Biophys J (2007) 1.13
Identification of VCP/p97, carboxyl terminus of Hsp70-interacting protein (CHIP), and amphiphysin II interaction partners using membrane-based human proteome arrays. Mol Cell Proteomics (2005) 1.13
Identification of Y-box binding protein 1 as a core regulator of MEK/ERK pathway-dependent gene signatures in colorectal cancer cells. PLoS Genet (2010) 1.12
A Y2H-seq approach defines the human protein methyltransferase interactome. Nat Methods (2013) 1.10
Detection of alpha-rod protein repeats using a neural network and application to huntingtin. PLoS Comput Biol (2009) 1.09
The induction levels of heat shock protein 70 differentiate the vulnerabilities to mutant huntingtin among neuronal subtypes. J Neurosci (2007) 1.08
Global parameter search reveals design principles of the mammalian circadian clock. BMC Syst Biol (2008) 1.08
Quantitative analysis of ultrasensitive responses. FEBS J (2005) 1.08
The synpolydactyly homolog (spdh) mutation in the mouse -- a defect in patterning and growth of limb cartilage elements. Mech Dev (2002) 1.06
Identification of distinct antibody epitopes and mimotopes from a peptide array of 5520 randomly generated sequences. J Immunol Methods (2002) 1.05
Periodicities of 10-11bp as indicators of the supercoiled state of genomic DNA. J Mol Biol (2004) 1.05
Association of CDH1 haplotypes with susceptibility to sporadic diffuse gastric cancer. Oncogene (2002) 1.04
How to achieve fast entrainment? The timescale to synchronization. PLoS One (2009) 1.04
Entrainment in a model of the mammalian circadian oscillator. J Biol Rhythms (2005) 1.03
UniHI 7: an enhanced database for retrieval and interactive analysis of human molecular interaction networks. Nucleic Acids Res (2013) 1.02
Small molecule inducers of heat-shock response reduce polyQ-mediated huntingtin aggregation. A possible therapeutic strategy. Neurodegener Dis (2007) 1.02
HuSiDa--the human siRNA database: an open-access database for published functional siRNA sequences and technical details of efficient transfer into recipient cells. Nucleic Acids Res (2005) 1.02
Evaluation of the benzothiazole aggregation inhibitors riluzole and PGL-135 as therapeutics for Huntington's disease. Neurobiol Dis (2005) 1.02
Therapeutic approaches to polyglutamine diseases: combating protein misfolding and aggregation. Curr Pharm Des (2006) 1.01
The Opitz syndrome gene product MID1 assembles a microtubule-associated ribonucleoprotein complex. Hum Genet (2008) 1.00
Nonlinear phenomena in contemporary vocal music. J Voice (2004) 0.98
DNA motifs and sequence periodicities. In Silico Biol (2006) 0.98
Multiplex approaches in protein microarray technology. Expert Rev Proteomics (2005) 0.97
Mutant huntingtin impairs Ku70-mediated DNA repair. J Cell Biol (2010) 0.97
Biomechanical modeling of register transitions and the role of vocal tract resonators. J Acoust Soc Am (2010) 0.96
Huntington's disease and its therapeutic target genes: a global functional profile based on the HD Research Crossroads database. BMC Neurol (2012) 0.96
CyanoEXpress: A web database for exploration and visualisation of the integrated transcriptome of cyanobacterium Synechocystis sp. PCC6803. Bioinformation (2012) 0.96
Ultrasensitization: switch-like regulation of cellular signaling by transcriptional induction. PLoS Comput Biol (2005) 0.95
Transcriptional repression induces a slowly progressive atypical neuronal death associated with changes of YAP isoforms and p73. J Cell Biol (2006) 0.95
Repeats and correlations in human DNA sequences. Phys Rev E Stat Nonlin Soft Matter Phys (2003) 0.94
Bifurcations and chaos in register transitions of excised larynx experiments. Chaos (2008) 0.93
Iron deprivation in Synechocystis: inference of pathways, non-coding RNAs, and regulatory elements from comprehensive expression profiling. G3 (Bethesda) (2012) 0.93
The interplay of cis-regulatory elements rules circadian rhythms in mouse liver. PLoS One (2012) 0.93
Why do cells cycle with a 24 hour period? Genome Inform (2006) 0.92
Histone deacetylase activity is retained in primary neurons expressing mutant huntingtin protein. J Neurochem (2003) 0.92