Published in J Mol Biol on May 22, 2007
A systematic survey identifies prions and illuminates sequence features of prionogenic proteins. Cell (2009) 6.20
Signal transduction by a fungal NOD-like receptor based on propagation of a prion amyloid fold. PLoS Biol (2015) 1.47
The functional curli amyloid is not based on in-register parallel beta-sheet structure. J Biol Chem (2009) 1.30
Structural dependence of HET-s amyloid fibril infectivity assessed by cryoelectron microscopy. Proc Natl Acad Sci U S A (2011) 0.99
A short history of small s: a prion of the fungus Podospora anserina. Prion (2007) 0.96
Characterization of the amyloid bacterial inclusion bodies of the HET-s fungal prion. Microb Cell Fact (2009) 0.95
Distinct subregions of Swi1 manifest striking differences in prion transmission and SWI/SNF function. Mol Cell Biol (2010) 0.92
Heterogeneous seeding of a prion structure by a generic amyloid form of the fungal prion-forming domain HET-s(218-289). J Biol Chem (2013) 0.92
Degradation of fungal prion HET-s(218-289) induces formation of a generic amyloid fold. Biophys J (2012) 0.91
Fungal prion HET-s as a model for structural complexity and self-propagation in prions. Proc Natl Acad Sci U S A (2014) 0.87
Contribution of specific residues of the β-solenoid fold to HET-s prion function, amyloid structure and stability. PLoS Pathog (2014) 0.86
Role of Hsp104 in the propagation and inheritance of the [Het-s] prion. Mol Biol Cell (2007) 0.85
Structural basis of infectious and non-infectious amyloids. Curr Alzheimer Res (2008) 0.83
Is supramolecular filament chirality the underlying cause of major morphology differences in amyloid fibrils? J Am Chem Soc (2014) 0.80
Identification of a novel cell death-inducing domain reveals that fungal amyloid-controlled programmed cell death is related to necroptosis. Proc Natl Acad Sci U S A (2016) 0.79
Heterogeneous seeding of HET-s(218-289) and the mutability of prion structures. Prion (2014) 0.78
A yeast toxic mutant of HET-s((218-289)) prion displays alternative intermediates of amyloidogenesis. Biophys J (2010) 0.77
Amyloids in solid-state nuclear magnetic resonance: potential causes of the usually low resolution. Int J Nanomedicine (2015) 0.76
Truncated forms of the prion protein PrP demonstrate the need for complexity in prion structure. Prion (2015) 0.75
Cell Adhesion on Amyloid Fibrils Lacking Integrin Recognition Motif. J Biol Chem (2016) 0.75
The Sm-like Hfq protein increases OxyS RNA interaction with target mRNAs. Mol Cell (2002) 5.69
Outcome of the first electron microscopy validation task force meeting. Structure (2012) 4.35
Correlation of structural elements and infectivity of the HET-s prion. Nature (2005) 4.01
Structure-based design of a fusion glycoprotein vaccine for respiratory syncytial virus. Science (2013) 3.90
Three-dimensional structure of herpes simplex virus from cryo-electron tomography. Science (2003) 3.82
Influenza virus pleiomorphy characterized by cryoelectron tomography. Proc Natl Acad Sci U S A (2006) 3.25
AGGRESCAN: a server for the prediction and evaluation of "hot spots" of aggregation in polypeptides. BMC Bioinformatics (2007) 3.02
Structure of RSV fusion glycoprotein trimer bound to a prefusion-specific neutralizing antibody. Science (2013) 2.95
Dynamics of herpes simplex virus capsid maturation visualized by time-lapse cryo-electron microscopy. Nat Struct Biol (2003) 2.78
Structural and functional similarities between the capsid proteins of bacteriophages T4 and HK97 point to a common ancestry. Proc Natl Acad Sci U S A (2005) 2.53
Prion generation in vitro: amyloid of Ure2p is infectious. EMBO J (2005) 2.42
Amyloid aggregates of the HET-s prion protein are infectious. Proc Natl Acad Sci U S A (2002) 2.37
Arrangement of L2 within the papillomavirus capsid. J Virol (2008) 2.37
Structural engineering of a phage lysin that targets gram-negative pathogens. Proc Natl Acad Sci U S A (2012) 2.36
Structure and polymorphism of the UL6 portal protein of herpes simplex virus type 1. J Virol (2004) 2.35
Functional architecture of the retromer cargo-recognition complex. Nature (2007) 2.26
The structure of the poliovirus 135S cell entry intermediate at 10-angstrom resolution reveals the location of an externalized polypeptide that binds to membranes. J Virol (2005) 2.20
Scrambled prion domains form prions and amyloid. Mol Cell Biol (2004) 2.00
Allosteric signaling and a nuclear exit strategy: binding of UL25/UL17 heterodimers to DNA-Filled HSV-1 capsids. Mol Cell (2007) 1.96
Amyloid-like properties of bacterial inclusion bodies. J Mol Biol (2005) 1.90
Computational resources for cryo-electron tomography in Bsoft. J Struct Biol (2007) 1.87
A resolution criterion for electron tomography based on cross-validation. J Struct Biol (2005) 1.85
Domain organization and structure-function relationship of the HET-s prion protein of Podospora anserina. EMBO J (2003) 1.80
Aggregation as bacterial inclusion bodies does not imply inactivation of enzymes and fluorescent proteins. Microb Cell Fact (2005) 1.79
Visualization of a missing link in retrovirus capsid assembly. Nature (2009) 1.75
Characterization of beta-sheet structure in Ure2p1-89 yeast prion fibrils by solid-state nuclear magnetic resonance. Biochemistry (2007) 1.73
Membrane curvature induction and tubulation are common features of synucleins and apolipoproteins. J Biol Chem (2010) 1.69
Architecture of Ure2p prion filaments: the N-terminal domains form a central core fiber. J Biol Chem (2003) 1.66
High-resolution mass spectrometry of viral assemblies: molecular composition and stability of dimorphic hepatitis B virus capsids. Proc Natl Acad Sci U S A (2008) 1.64
Visualization of the herpes simplex virus portal in situ by cryo-electron tomography. Virology (2006) 1.63
A model for Ure2p prion filaments and other amyloids: the parallel superpleated beta-structure. Proc Natl Acad Sci U S A (2004) 1.62
Mechanism of inactivation on prion conversion of the Saccharomyces cerevisiae Ure2 protein. Proc Natl Acad Sci U S A (2002) 1.61
A novel class of herpesvirus with bivalve hosts. J Gen Virol (2005) 1.60
The parallel superpleated beta-structure as a model for amyloid fibrils of human amylin. J Mol Biol (2005) 1.56
Implications of the HIV-1 Rev dimer structure at 3.2 A resolution for multimeric binding to the Rev response element. Proc Natl Acad Sci U S A (2010) 1.51
Structural basis for iron piracy by pathogenic Neisseria. Nature (2012) 1.50
Structural basis for the coordinated regulation of transglutaminase 3 by guanine nucleotides and calcium/magnesium. J Biol Chem (2003) 1.50
Sexual transmission of the [Het-S] prion leads to meiotic drive in Podospora anserina. Proc Natl Acad Sci U S A (2003) 1.44
A non-Q/N-rich prion domain of a foreign prion, [Het-s], can propagate as a prion in yeast. Mol Cell (2007) 1.43
Beta-rolls, beta-helices, and other beta-solenoid proteins. Adv Protein Chem (2006) 1.37
Beta arcades: recurring motifs in naturally occurring and disease-related amyloid fibrils. FASEB J (2009) 1.37
Mass analysis by scanning transmission electron microscopy and electron diffraction validate predictions of stacked beta-solenoid model of HET-s prion fibrils. J Biol Chem (2006) 1.36
Prediction of "hot spots" of aggregation in disease-linked polypeptides. BMC Struct Biol (2005) 1.34
The HET-s prion protein of the filamentous fungus Podospora anserina aggregates in vitro into amyloid-like fibrils. J Biol Chem (2001) 1.33
HIV-1 maturation inhibitor bevirimat stabilizes the immature Gag lattice. J Virol (2010) 1.33
Design, selection, and characterization of thioflavin-based intercalation compounds with metal chelating properties for application in Alzheimer's disease. J Am Chem Soc (2009) 1.32
The mechanism of toxicity in HET-S/HET-s prion incompatibility. PLoS Biol (2012) 1.31
Maturation of flaviviruses starts from one or more icosahedrally independent nucleation centres. EMBO Rep (2011) 1.31
Structural changes in Influenza virus at low pH characterized by cryo-electron tomography. J Virol (2012) 1.30
Prospects of electron cryotomography to visualize macromolecular complexes inside cellular compartments: implications of crowding. Biophys Chem (2003) 1.30
The morphogenic linker peptide of HBV capsid protein forms a mobile array on the interior surface. EMBO J (2002) 1.29
Prions: proteins as genes and infectious entities. Genes Dev (2004) 1.29
Mutagenesis of the central hydrophobic cluster in Abeta42 Alzheimer's peptide. Side-chain properties correlate with aggregation propensities. FEBS J (2006) 1.29
mtCLIC/CLIC4, an organellular chloride channel protein, is increased by DNA damage and participates in the apoptotic response to p53. Mol Cell Biol (2002) 1.28
An externalized polypeptide partitions between two distinct sites on genome-released poliovirus particles. J Virol (2011) 1.26
Electron microscopic evidence in support of alpha-solenoid models of proteasomal subunits Rpn1 and Rpn2. J Mol Biol (2009) 1.25
Autophagy is induced during cell death by incompatibility and is essential for differentiation in the filamentous fungus Podospora anserina. Mol Microbiol (2003) 1.25
Control of crosslinking by quaternary structure changes during bacteriophage HK97 maturation. Mol Cell (2004) 1.25
Structure of human carboxypeptidase A4 with its endogenous protein inhibitor, latexin. Proc Natl Acad Sci U S A (2005) 1.25
Functional proteolytic complexes of the human mitochondrial ATP-dependent protease, hClpXP. J Biol Chem (2002) 1.24
Human immunodeficiency virus type 1 N-terminal capsid mutants containing cores with abnormally high levels of capsid protein and virtually no reverse transcriptase. J Virol (2003) 1.24
Amyloids in bacterial inclusion bodies. Trends Biochem Sci (2009) 1.24
Time-resolved molecular dynamics of bacteriophage HK97 capsid maturation interpreted by electron cryo-microscopy and X-ray crystallography. J Struct Biol (2005) 1.24
Inclusion bodies: specificity in their aggregation process and amyloid-like structure. Biochim Biophys Acta (2008) 1.24
New HEAT-like repeat motifs in proteins regulating proteasome structure and function. J Struct Biol (2004) 1.23
δ-Tocopherol reduces lipid accumulation in Niemann-Pick type C1 and Wolman cholesterol storage disorders. J Biol Chem (2012) 1.23
The axial channel of the 20S proteasome opens upon binding of the PA200 activator. J Mol Biol (2005) 1.22
Handedness of the herpes simplex virus capsid and procapsid. J Virol (2002) 1.21
Protein aggregation: mechanisms and functional consequences. Int J Biochem Cell Biol (2012) 1.20
Stability and shape of hepatitis B virus capsids in vacuo. Angew Chem Int Ed Engl (2008) 1.20
Crosslinking renders bacteriophage HK97 capsid maturation irreversible and effects an essential stabilization. EMBO J (2005) 1.20
A thermally induced phase transition in a viral capsid transforms the hexamers, leaving the pentamers unchanged. J Struct Biol (2006) 1.20
A free energy cascade with locks drives assembly and maturation of bacteriophage HK97 capsid. J Mol Biol (2006) 1.20
RSV capsid polymorphism correlates with polymerization efficiency and envelope glycoprotein content: implications that nucleation controls morphogenesis. J Mol Biol (2007) 1.19
The turn of the screw: variations of the abundant beta-solenoid motif in passenger domains of Type V secretory proteins. J Struct Biol (2006) 1.18
A second symmetry mismatch at the portal vertex of bacteriophage T7: 8-fold symmetry in the procapsid core. J Mol Biol (2003) 1.18
Prion genetics: new rules for a new kind of gene. Annu Rev Genet (2004) 1.18
Genesis of a fungal non-self recognition repertoire. PLoS One (2007) 1.17
Fungal incompatibility: evolutionary origin in pathogen defense? Bioessays (2009) 1.17
Molecular mechanisms in bacteriophage T7 procapsid assembly, maturation, and DNA containment. Adv Protein Chem (2003) 1.16
The mechanism of prion inhibition by HET-S. Mol Cell (2010) 1.14
Recombinant HA1 produced in E. coli forms functional oligomers and generates strain-specific SRID potency antibodies for pandemic influenza vaccines. Vaccine (2011) 1.14
Alternating translocation of protein substrates from both ends of ClpXP protease. EMBO J (2002) 1.14
Initial stages of V(D)J recombination: the organization of RAG1/2 and RSS DNA in the postcleavage complex. Mol Cell (2009) 1.13
The N-terminal substrate-binding domain of ClpA unfoldase is highly mobile and extends axially from the distal surface of ClpAP protease. J Struct Biol (2004) 1.13
The role of capsid maturation on adenovirus priming for sequential uncoating. J Biol Chem (2012) 1.13
Fibril structure of human islet amyloid polypeptide. J Biol Chem (2011) 1.12
Irregular and Semi-Regular Polyhedral Models for Rous Sarcoma Virus Cores. Comput Math Methods Med (2008) 1.12
Recent structural and computational insights into conformational diseases. Curr Med Chem (2008) 1.12