Published in Nat Cell Biol on June 01, 2007
Epidermal barrier in atopic dermatitis. Allergy Asthma Immunol Res (2011) 1.04
Kallikrein-related peptidase-7 regulates caspase-14 maturation during keratinocyte terminal differentiation by generating an intermediate form. J Biol Chem (2012) 0.80
Pathophysiological Significance of Hepatic Apoptosis. ISRN Hepatol (2012) 0.79
Effect of Standardized Boesenbergia pandurata Extract and Its Active Compound Panduratin A on Skin Hydration and Barrier Function in Human Epidermal Keratinocytes. Prev Nutr Food Sci (2015) 0.75
Caspase-14 protects against epidermal UVB photodamage and water loss. Nat Cell Biol (2007) 2.82
Guidelines for the use and interpretation of assays for monitoring autophagy. Autophagy (2012) 20.08
Regulation of cell death: the calcium-apoptosis link. Nat Rev Mol Cell Biol (2003) 9.07
The cornified envelope: a model of cell death in the skin. Nat Rev Mol Cell Biol (2005) 6.27
TAp73 knockout shows genomic instability with infertility and tumor suppressor functions. Genes Dev (2008) 4.85
Targeting autophagy potentiates tyrosine kinase inhibitor-induced cell death in Philadelphia chromosome-positive cells, including primary CML stem cells. J Clin Invest (2009) 3.55
The HECT family of E3 ubiquitin ligases: multiple players in cancer development. Cancer Cell (2008) 3.35
Cleavage of the plasma membrane Na+/Ca2+ exchanger in excitotoxicity. Cell (2005) 2.63
The ubiquitin-protein ligase Itch regulates p73 stability. EMBO J (2005) 2.38
The p53 family: guardians of maternal reproduction. Nat Rev Mol Cell Biol (2011) 2.13
Toxicology: a risky business. Nature (2002) 2.10
Isoform-specific p73 knockout mice reveal a novel role for delta Np73 in the DNA damage response pathway. Genes Dev (2010) 2.06
MicroRNA 217 modulates endothelial cell senescence via silent information regulator 1. Circulation (2009) 2.05
Inhibition of the c-Abl-TAp63 pathway protects mouse oocytes from chemotherapy-induced death. Nat Med (2009) 2.03
The E3 ubiquitin ligase Itch controls the protein stability of p63. Proc Natl Acad Sci U S A (2006) 2.01
Loss of p63 and its microRNA-205 target results in enhanced cell migration and metastasis in prostate cancer. Proc Natl Acad Sci U S A (2012) 1.97
Functional association between Wwox tumor suppressor protein and p73, a p53 homolog. Proc Natl Acad Sci U S A (2004) 1.91
TAp63alpha induces apoptosis by activating signaling via death receptors and mitochondria. EMBO J (2005) 1.90
MiR-203 controls proliferation, migration and invasive potential of prostate cancer cell lines. Cell Cycle (2011) 1.89
Tissue transglutaminase does not affect fibrotic matrix stability or regression of liver fibrosis in mice. Gastroenterology (2011) 1.85
TAp63 and DeltaNp63 in cancer and epidermal development. Cell Cycle (2007) 1.84
The impact of p53 and p73 on aneuploidy and cancer. Trends Cell Biol (2008) 1.76
DeltaNp63 regulates thymic development through enhanced expression of FgfR2 and Jag2. Proc Natl Acad Sci U S A (2007) 1.70
microRNA-34a regulates neurite outgrowth, spinal morphology, and function. Proc Natl Acad Sci U S A (2011) 1.60
Neuronal differentiation by TAp73 is mediated by microRNA-34a regulation of synaptic protein targets. Proc Natl Acad Sci U S A (2011) 1.58
Regulation of the apoptosis-necrosis switch. Oncogene (2004) 1.54
FLASH and NPAT positive but not Coilin positive Cajal Bodies correlate with cell ploidy. Cell Cycle (2008) 1.52
p63, a story of mice and men. J Invest Dermatol (2011) 1.50
New p63 targets in keratinocytes identified by a genome-wide approach. EMBO J (2006) 1.50
Transglutaminase 2-/- mice reveal a phagocytosis-associated crosstalk between macrophages and apoptotic cells. Proc Natl Acad Sci U S A (2003) 1.48
Negative regulation of the Hippo pathway by E3 ubiquitin ligase ITCH is sufficient to promote tumorigenicity. Cancer Res (2011) 1.47
TAp73 depletion accelerates aging through metabolic dysregulation. Genes Dev (2012) 1.45
Ca2+ signals and neuronal death in brain ischemia. Stroke (2007) 1.45
Cell death mechanisms and their implications in toxicology. Toxicol Sci (2010) 1.43
p73 induces apoptosis by different mechanisms. Biochem Biophys Res Commun (2005) 1.42
One, two, three--p53, p63, p73 and chemosensitivity. Drug Resist Updat (2007) 1.41
p63-microRNA feedback in keratinocyte senescence. Proc Natl Acad Sci U S A (2012) 1.41
A novel recessive connexin 31 (GJB3) mutation in a case of erythrokeratodermia variabilis. J Invest Dermatol (2004) 1.39
Isoform-specific monoubiquitination, endocytosis, and degradation of alternatively spliced ErbB4 isoforms. Proc Natl Acad Sci U S A (2008) 1.39
Tissue transglutaminase contributes to interstitial renal fibrosis by favoring accumulation of fibrillar collagen through TGF-beta activation and cell infiltration. Am J Pathol (2008) 1.38
p63 is upstream of IKK alpha in epidermal development. J Cell Sci (2006) 1.35
TAp73 regulates the spindle assembly checkpoint by modulating BubR1 activity. Proc Natl Acad Sci U S A (2009) 1.34
A homozygous missense mutation in TGM5 abolishes epidermal transglutaminase 5 activity and causes acral peeling skin syndrome. Am J Hum Genet (2005) 1.33
PIAS-1 is a checkpoint regulator which affects exit from G1 and G2 by sumoylation of p73. Mol Cell Biol (2004) 1.33
p73 in Cancer. Genes Cancer (2011) 1.33
GLS2 is transcriptionally regulated by p73 and contributes to neuronal differentiation. Cell Cycle (2013) 1.32
Streptococcus pneumoniae deficient in pneumolysin or autolysin has reduced virulence in meningitis. J Infect Dis (2008) 1.31
The nystagmus-associated FRMD7 gene regulates neuronal outgrowth and development. Hum Mol Genet (2009) 1.30
The tumor suppressor Pml regulates cell fate in the developing neocortex. Nat Neurosci (2009) 1.30
p53 is cleaved by caspases generating fragments localizing to mitochondria. J Biol Chem (2006) 1.30
Mule/Huwe1/Arf-BP1 suppresses Ras-driven tumorigenesis by preventing c-Myc/Miz1-mediated down-regulation of p21 and p15. Genes Dev (2013) 1.30
miR-7 and miR-214 are specifically expressed during neuroblastoma differentiation, cortical development and embryonic stem cells differentiation, and control neurite outgrowth in vitro. Biochem Biophys Res Commun (2010) 1.29
Transglutaminase-dependent RhoA activation and depletion by serotonin in vascular smooth muscle cells. J Biol Chem (2006) 1.27
Caspase-dependent alterations of Ca2+ signaling in the induction of apoptosis by hepatitis B virus X protein. J Biol Chem (2003) 1.26
p73 regulates maintenance of neural stem cell. Biochem Biophys Res Commun (2010) 1.25
Ubiquitin-dependent degradation of p73 is inhibited by PML. J Exp Med (2004) 1.24
Epithelial transglutaminase 2 is needed for T cell interleukin-17 production and subsequent pulmonary inflammation and fibrosis in bleomycin-treated mice. J Exp Med (2011) 1.23
Desmethylclomipramine induces the accumulation of autophagy markers by blocking autophagic flux. J Cell Sci (2009) 1.20
MicroRNAs in age-related diseases. EMBO Mol Med (2013) 1.20
The Nedd4-binding partner 1 (N4BP1) protein is an inhibitor of the E3 ligase Itch. Proc Natl Acad Sci U S A (2007) 1.19
Roles for p53 and p73 during oligodendrocyte development. Development (2004) 1.18
Calcium-dependent dephosphorylation of the histone chaperone DAXX regulates H3.3 loading and transcription upon neuronal activation. Neuron (2012) 1.18
GADD153 and 12-lipoxygenase mediate fenretinide-induced apoptosis of neuroblastoma. Cancer Res (2002) 1.16
Targeting of the Arpc3 actin nucleation factor by miR-29a/b regulates dendritic spine morphology. J Cell Biol (2011) 1.14
A novel RGD-independent cel adhesion pathway mediated by fibronectin-bound tissue transglutaminase rescues cells from anoikis. J Biol Chem (2003) 1.14
miR-146a is modulated in human endothelial cell with aging. Atherosclerosis (2011) 1.14
E1A activates transcription of p73 and Noxa to induce apoptosis. J Biol Chem (2004) 1.14
Transglutaminase 2 is needed for the formation of an efficient phagocyte portal in macrophages engulfing apoptotic cells. J Immunol (2009) 1.13
Respiratory distress and perinatal lethality in Nedd4-2-deficient mice. Nat Commun (2011) 1.13
p63 regulates glutaminase 2 expression. Cell Cycle (2013) 1.12
Differential altered stability and transcriptional activity of ΔNp63 mutants in distinct ectodermal dysplasias. J Cell Sci (2011) 1.11
Role of transglutaminase 2 in glucose tolerance: knockout mice studies and a putative mutation in a MODY patient. FASEB J (2002) 1.11
Itch self-polyubiquitylation occurs through lysine-63 linkages. Biochem Pharmacol (2008) 1.09
The antiapoptotic DeltaNp73 is degraded in a c-Jun-dependent manner upon genotoxic stress through the antizyme-mediated pathway. Proc Natl Acad Sci U S A (2010) 1.09
p53 is upregulated in Alzheimer's disease and induces tau phosphorylation in HEK293a cells. Neurosci Lett (2007) 1.08
Differential control of TAp73 and DeltaNp73 protein stability by the ring finger ubiquitin ligase PIR2. Proc Natl Acad Sci U S A (2010) 1.08
p73: a multifunctional protein in neurobiology. Mol Neurobiol (2011) 1.07
Ca2+ signals and death programmes in neurons. Philos Trans R Soc Lond B Biol Sci (2005) 1.07
Identification of NCF2/p67phox as a novel p53 target gene. Cell Cycle (2012) 1.07
The dawning of a new age of toxicology. ALTEX (2008) 1.06
Transglutaminase type II plays a protective role in hepatic injury. Am J Pathol (2003) 1.06
Chemotherapy-induced apoptosis in hepatocellular carcinoma involves the p53 family and is mediated via the extrinsic and the intrinsic pathway. Int J Cancer (2010) 1.05
miR-24 triggers epidermal differentiation by controlling actin adhesion and cell migration. J Cell Biol (2012) 1.04
Cell death pathology: cross-talk with autophagy and its clinical implications. Biochem Biophys Res Commun (2011) 1.04
Expression of transglutaminase 5 in normal and pathologic human epidermis. J Invest Dermatol (2002) 1.04
NF-kappaB inhibits T-cell activation-induced, p73-dependent cell death by induction of MDM2. Proc Natl Acad Sci U S A (2010) 1.03
Lysine-specific modifications of p53: a matter of life and death? Oncotarget (2013) 1.03
Cell death pathology: perspective for human diseases. Biochem Biophys Res Commun (2011) 1.03
New antibodies recognizing p73: comparison with commercial antibodies. Biochem Biophys Res Commun (2005) 1.02
p73-alpha is capable of inducing scotin and ER stress. Oncogene (2004) 1.02
Mechanisms of free-radical induction in relation to fenretinide-induced apoptosis of neuroblastoma. J Cell Biochem (2003) 1.01
Regulation of the p73 protein stability and degradation. Biochem Biophys Res Commun (2005) 1.00
TGFbeta mediates activation of transglutaminase 2 in response to oxidative stress that leads to protein aggregation. FASEB J (2008) 1.00
Oxidative stress activation of miR-125b is part of the molecular switch for Hailey-Hailey disease manifestation. Exp Dermatol (2011) 1.00
Expression of GATA-3 in epidermis and hair follicle: relationship to p63. Biochem Biophys Res Commun (2007) 0.99
Inhibitor of apoptosis-stimulating protein of p53 (iASPP) prevents senescence and is required for epithelial stratification. Proc Natl Acad Sci U S A (2011) 0.99