Published in J Cell Biochem on August 15, 2008
A tense situation: forcing tumour progression. Nat Rev Cancer (2009) 7.80
Hydrogels as extracellular matrix mimics for 3D cell culture. Biotechnol Bioeng (2009) 4.72
A nuclear-envelope bridge positions nuclei and moves chromosomes. J Cell Sci (2009) 2.10
Genetic diseases of connective tissues: cellular and extracellular effects of ECM mutations. Nat Rev Genet (2009) 2.03
Micro-environmental mechanical stress controls tumor spheroid size and morphology by suppressing proliferation and inducing apoptosis in cancer cells. PLoS One (2009) 1.92
Abnormal development of the cerebral cortex and cerebellum in the setting of lamin B2 deficiency. Proc Natl Acad Sci U S A (2010) 1.89
Three-dimensional biomaterials for the study of human pluripotent stem cells. Nat Methods (2011) 1.42
Nesprin-3 regulates endothelial cell morphology, perinuclear cytoskeletal architecture, and flow-induced polarization. Mol Biol Cell (2011) 1.18
Nesprins: from the nuclear envelope and beyond. Expert Rev Mol Med (2013) 1.15
Nonlinear osmotic properties of the cell nucleus. Ann Biomed Eng (2008) 1.00
Mechanotransduction and fibrosis. J Biomech (2014) 0.97
Force-dependent cell signaling in stem cell differentiation. Stem Cell Res Ther (2012) 0.97
Extracellular matrix synthesis in vascular disease: hypertension, and atherosclerosis. J Biomed Res (2013) 0.93
Contributions of extracellular matrix signaling and tissue architecture to nuclear mechanisms and spatial organization of gene expression control. Biochim Biophys Acta (2009) 0.93
Bidirectional extracellular matrix signaling during tissue morphogenesis. Cytokine Growth Factor Rev (2009) 0.93
Tissue stretch induces nuclear remodeling in connective tissue fibroblasts. Histochem Cell Biol (2010) 0.93
Hemodynamic disturbed flow induces differential DNA methylation of endothelial Kruppel-Like Factor 4 promoter in vitro and in vivo. Circ Res (2014) 0.90
Slow stretching that mimics embryonic growth rate stimulates structural and mechanical development of tendon-like tissue in vitro. Dev Dyn (2011) 0.90
Effects of S1P on skeletal muscle repair/regeneration during eccentric contraction. J Cell Mol Med (2011) 0.86
In situ mechanical interferometry of matrigel films. Langmuir (2009) 0.85
Particle-induced indentation of the alveolar epithelium caused by surface tension forces. J Appl Physiol (1985) (2010) 0.85
Physicochemical and biomechanical stimuli in cell-based articular cartilage repair. Curr Rheumatol Rep (2015) 0.84
Evidence that mechanosensors with distinct biomechanical properties allow for specificity in mechanotransduction. Biophys J (2009) 0.84
Extracellular matrix and the mechanics of large artery development. Biomech Model Mechanobiol (2012) 0.84
In vitro cerebrovascular modeling in the 21st century: current and prospective technologies. Pharm Res (2014) 0.84
Nmp4/CIZ: road block at the intersection of PTH and load. Bone (2009) 0.82
Reduction of fibroblast size/mechanical force down-regulates TGF-β type II receptor: implications for human skin aging. Aging Cell (2015) 0.82
Mechanotransduction and nuclear function. Curr Opin Cell Biol (2016) 0.82
A Role of Myocardin Related Transcription Factor-A (MRTF-A) in Scleroderma Related Fibrosis. PLoS One (2015) 0.82
Regulating tension in three-dimensional culture environments. Exp Cell Res (2013) 0.81
Age-associated reduction of cellular spreading/mechanical force up-regulates matrix metalloproteinase-1 expression and collagen fibril fragmentation via c-Jun/AP-1 in human dermal fibroblasts. Aging Cell (2014) 0.80
A Mechanomodulatory Device to Minimize Incisional Scar Formation. Adv Wound Care (New Rochelle) (2013) 0.79
Age-associated reduction of cell spreading induces mitochondrial DNA common deletion by oxidative stress in human skin dermal fibroblasts: implication for human skin connective tissue aging. J Biomed Sci (2015) 0.78
Mechanical phenotype is important for stromal aromatase expression. Steroids (2011) 0.77
Spatial organization of fibroblast nuclear chromocenters: component tree analysis. J Anat (2013) 0.76
Effect of solid freeform fabrication-based polycaprolactone/poly(lactic-co-glycolic acid)/collagen scaffolds on cellular activities of human adipose-derived stem cells and rat primary hepatocytes. J Mater Sci Mater Med (2013) 0.75
Age-related reduction of dermal fibroblast size up-regulates multiple matrix metalloproteinases as observed in aged human skin in vivo. Br J Dermatol (2017) 0.75
PARP inhibition: PARP1 and beyond. Nat Rev Cancer (2010) 6.70
Enzymatic activity associated with class II HDACs is dependent on a multiprotein complex containing HDAC3 and SMRT/N-CoR. Mol Cell (2002) 5.19
Proteome-wide identification of poly(ADP-ribose) binding proteins and poly(ADP-ribose)-associated protein complexes. Nucleic Acids Res (2008) 2.70
PARP1-dependent kinetics of recruitment of MRE11 and NBS1 proteins to multiple DNA damage sites. J Biol Chem (2007) 2.62
RNF8- and RNF168-dependent degradation of KDM4A/JMJD2A triggers 53BP1 recruitment to DNA damage sites. EMBO J (2012) 2.34
Using FRAP and mathematical modeling to determine the in vivo kinetics of nuclear proteins. Methods (2003) 2.15
ATM-dependent DNA damage-independent mitotic phosphorylation of H2AX in normally growing mammalian cells. Mol Biol Cell (2005) 2.13
Catalytic function of the PR-Set7 histone H4 lysine 20 monomethyltransferase is essential for mitotic entry and genomic stability. J Biol Chem (2008) 1.99
Nucleoplasmic beta-actin exists in a dynamic equilibrium between low-mobility polymeric species and rapidly diffusing populations. J Cell Biol (2006) 1.98
Overexpression of transcripts originating from the MMSET locus characterizes all t(4;14)(p16;q32)-positive multiple myeloma patients. Blood (2005) 1.81
Ataxia telangiectasia mutated (ATM) signaling network is modulated by a novel poly(ADP-ribose)-dependent pathway in the early response to DNA-damaging agents. J Biol Chem (2007) 1.80
BMI1-mediated histone ubiquitylation promotes DNA double-strand break repair. J Cell Biol (2010) 1.74
H1 family histones in the nucleus. Control of binding and localization by the C-terminal domain. J Biol Chem (2005) 1.59
The differential mobilization of histones H3.1 and H3.3 by herpes simplex virus 1 relates histone dynamics to the assembly of viral chromatin. PLoS Pathog (2013) 1.42
Actin dynamics and functions in the interphase nucleus: moving toward an understanding of nuclear polymeric actin. Biochem Cell Biol (2009) 1.38
The expanding role of poly(ADP-ribose) metabolism: current challenges and new perspectives. Curr Opin Cell Biol (2006) 1.35
Targeting poly(ADP-ribosyl)ation: a promising approach in cancer therapy. Trends Mol Med (2005) 1.29
Quantitative analysis of CBP- and P300-induced histone acetylations in vivo using native chromatin. Mol Cell Biol (2003) 1.29
PARP activation regulates the RNA-binding protein NONO in the DNA damage response to DNA double-strand breaks. Nucleic Acids Res (2012) 1.28
Dynamic changes in histone H3 lysine 9 methylations: identification of a mitosis-specific function for dynamic methylation in chromosome congression and segregation. J Biol Chem (2005) 1.24
The cytotoxicity of gamma-secretase inhibitor I to breast cancer cells is mediated by proteasome inhibition, not by gamma-secretase inhibition. Breast Cancer Res (2009) 1.19
The gamma-H2A.X: is it just a surrogate marker of double-strand breaks or much more? Environ Mol Mutagen (2008) 1.18
Kdm4b histone demethylase is a DNA damage response protein and confers a survival advantage following γ-irradiation. J Biol Chem (2013) 1.17
Characterization of the histone H2A.Z-1 and H2A.Z-2 isoforms in vertebrates. BMC Biol (2009) 1.17
Depletion of nuclear actin is a key mediator of quiescence in epithelial cells. J Cell Sci (2011) 1.16
Polycomb group protein gene silencing, non-coding RNA, stem cells, and cancer. Biochem Cell Biol (2009) 1.16
CBX4-mediated SUMO modification regulates BMI1 recruitment at sites of DNA damage. Nucleic Acids Res (2012) 1.16
Polycomb group proteins in the DNA damage response: a link between radiation resistance and "stemness". Cell Cycle (2011) 1.14
Investigation of PARP-1, PARP-2, and PARG interactomes by affinity-purification mass spectrometry. Proteome Sci (2010) 1.14
Proteomic investigation of phosphorylation sites in poly(ADP-ribose) polymerase-1 and poly(ADP-ribose) glycohydrolase. J Proteome Res (2009) 1.14
Methylation of MRE11 regulates its nuclear compartmentalization. Cell Cycle (2005) 1.06
Quantification of protein-protein and protein-DNA interactions in vivo, using fluorescence recovery after photobleaching. Methods Enzymol (2004) 1.03
Molecular dynamics of histone H1. Biochem Cell Biol (2009) 1.03
H2A.Bbd: an X-chromosome-encoded histone involved in mammalian spermiogenesis. Nucleic Acids Res (2009) 1.01
MUC1 initiates Src-CrkL-Rac1/Cdc42-mediated actin cytoskeletal protrusive motility after ligating intercellular adhesion molecule-1. Mol Cancer Res (2008) 0.99
The relationship between histone H3 phosphorylation and acetylation throughout the mammalian cell cycle. Biochem Cell Biol (2006) 0.99
Phosphorylation of polynucleotide kinase/ phosphatase by DNA-dependent protein kinase and ataxia-telangiectasia mutated regulates its association with sites of DNA damage. Nucleic Acids Res (2011) 0.99
Distinct dynamics and distribution of histone methyl-lysine derivatives in mouse development. Dev Biol (2004) 0.99
Polycomb repressive complex 2 contributes to DNA double-strand break repair. Cell Cycle (2013) 0.98
The transcriptional regulator CBP has defined spatial associations within interphase nuclei. PLoS Comput Biol (2006) 0.97
Notch signaling as a therapeutic target for breast cancer treatment? Breast Cancer Res (2011) 0.97
Dynamic relocation of poly(ADP-ribose) glycohydrolase isoforms during radiation-induced DNA damage. Biochim Biophys Acta (2005) 0.97
F-actin-dependent insolubility of chromatin-modifying components. J Biol Chem (2004) 0.93
G2 histone methylation is required for the proper segregation of chromosomes. J Cell Sci (2009) 0.93
The oncogenic potential of Jumonji D2 (JMJD2/KDM4) histone demethylase overexpression. Biochem Cell Biol (2012) 0.92
Quantitative analysis reveals asynchronous and more than DSB-associated histone H2AX phosphorylation after exposure to ionizing radiation. Radiat Res (2006) 0.92
Poly(ADP-ribose) glycohydrolase is a component of the FMRP-associated messenger ribonucleoparticles. Biochem J (2005) 0.89
Core histone hyperacetylation impacts cooperative behavior and high-affinity binding of histone H1 to chromatin. Biochemistry (2010) 0.89
Linker histones are mobilized during infection with herpes simplex virus type 1. J Virol (2008) 0.89
A small molecule inhibitor of polycomb repressive complex 1 inhibits ubiquitin signaling at DNA double-strand breaks. J Biol Chem (2013) 0.88
Using quantitative imaging microscopy to define the target substrate specificities of histone post-translational-modifying enzymes. Methods (2005) 0.88
Proteome-wide identification of WRN-interacting proteins in untreated and nuclease-treated samples. J Proteome Res (2011) 0.88
Epigenetic differences between human papillomavirus-positive and -negative oropharyngeal squamous cell carcinomas. J Otolaryngol Head Neck Surg (2012) 0.88
Epigenetics regulate centromere formation and kinetochore function. J Cell Biochem (2008) 0.87
Epigenetic regulation of centromere formation and kinetochore function. Biochem Cell Biol (2006) 0.85
Core histones H2B and H4 are mobilized during infection with herpes simplex virus 1. J Virol (2011) 0.83
Subnuclear localization and mobility are key indicators of PAX3 dysfunction in Waardenburg syndrome. Hum Mol Genet (2008) 0.83
A requirement for polymerized actin in DNA double-strand break repair. Nucleus (2012) 0.82
The PAX3 paired domain and homeodomain function as a single binding module in vivo to regulate subnuclear localization and mobility by a mechanism that requires base-specific recognition. J Mol Biol (2010) 0.81
A key role for poly(ADP-ribose) polymerase 3 in ectodermal specification and neural crest development. PLoS One (2011) 0.81
Pin1 promotes histone H1 dephosphorylation and stabilizes its binding to chromatin. J Cell Biol (2013) 0.78
Characterization and comparison of protein complexes initiated by the intracellular domain of individual Notch paralogs. Biochem Biophys Res Commun (2011) 0.77
Correction: The Differential Mobilization of Histones H3.1 and H3.3 by Herpes Simplex Virus 1 Relates Histone Dynamics to the Assembly of Viral Chromatin. PLoS Pathog (2016) 0.75
Conference Scene: epigenetics eh! The first formal meeting of the Canadian epigenetics community. Epigenomics (2011) 0.75