Published in Bone on September 18, 2009
Teriparatide therapy and beta-tricalcium phosphate enhance scaffold reconstruction of mouse femoral defects. Tissue Eng Part A (2010) 0.82
Nmp4/CIZ suppresses the response of bone to anabolic parathyroid hormone by regulating both osteoblasts and osteoclasts. Calcif Tissue Int (2011) 0.82
Nmp4/CIZ inhibits mechanically induced beta-catenin signaling activity in osteoblasts. J Cell Physiol (2010) 0.82
Immortalization and characterization of osteoblast cell lines generated from wild-type and Nmp4-null mouse bone marrow stromal cells using murine telomerase reverse transcriptase (mTERT). J Cell Physiol (2012) 0.80
Beyond the sequence: cellular organization of genome function. Cell (2007) 10.32
Canonical Wnt signaling in differentiated osteoblasts controls osteoclast differentiation. Dev Cell (2005) 7.64
Force sensing by mechanical extension of the Src family kinase substrate p130Cas. Cell (2006) 7.35
Demonstration of mechanical connections between integrins, cytoskeletal filaments, and nucleoplasm that stabilize nuclear structure. Proc Natl Acad Sci U S A (1997) 7.24
Molecular and cellular mechanisms of the anabolic effect of intermittent PTH. Bone (2007) 3.41
p130Cas: a versatile scaffold in signaling networks. Trends Cell Biol (2006) 2.84
Engineering gene expression and protein synthesis by modulation of nuclear shape. Proc Natl Acad Sci U S A (2002) 2.60
RAGE (Receptor for Advanced Glycation Endproducts), RAGE ligands, and their role in cancer and inflammation. J Transl Med (2009) 2.56
Proteasomal degradation of Runx2 shortens parathyroid hormone-induced anti-apoptotic signaling in osteoblasts. A putative explanation for why intermittent administration is needed for bone anabolism. J Biol Chem (2003) 2.44
Osteopontin expression is required for myofibroblast differentiation. Circ Res (2007) 2.33
Parathyroid hormone (PTH)-induced bone gain is blunted in SOST overexpressing and deficient mice. J Bone Miner Res (2010) 2.19
Molecular pathways mediating mechanical signaling in bone. Gene (2005) 2.17
The hLEF/TCF-1 alpha HMG protein contains a context-dependent transcriptional activation domain that induces the TCR alpha enhancer in T cells. Genes Dev (1993) 2.04
Extracellular signal-regulated kinase 5 SUMOylation antagonizes shear stress-induced antiinflammatory response and endothelial nitric oxide synthase expression in endothelial cells. Circ Res (2008) 2.01
Bone strength: current concepts. Ann N Y Acad Sci (2006) 1.80
Mechanical loading enhances the anabolic effects of intermittent parathyroid hormone (1-34) on trabecular and cortical bone in mice. Bone (2008) 1.76
Mechanical forces facilitate actin polymerization at focal adhesions in a zyxin-dependent manner. J Cell Sci (2008) 1.71
Effects of parathyroid hormone on Wnt signaling pathway in bone. J Cell Biochem (2005) 1.71
Beta-catenin levels influence rapid mechanical responses in osteoblasts. J Biol Chem (2008) 1.60
Bone response to intermittent parathyroid hormone is altered in mice null for {beta}-Arrestin2. Endocrinology (2005) 1.49
A model for mechanotransduction in bone cells: the load-bearing mechanosomes. J Cell Biochem (2003) 1.45
Mechanotransduction from the ECM to the genome: are the pieces now in place? J Cell Biochem (2008) 1.45
beta-Arrestin2 regulates the differential response of cortical and trabecular bone to intermittent PTH in female mice. J Bone Miner Res (2004) 1.39
Primary hyperparathyroidism and the skeleton. Clin Endocrinol (Oxf) (2008) 1.26
Cell shape regulates collagen type I expression in human tendon fibroblasts. Cell Motil Cytoskeleton (2008) 1.21
Focal adhesion protein zyxin is a mechanosensitive modulator of gene expression in vascular smooth muscle cells. Hypertension (2004) 1.18
CIZ, a zinc finger protein that interacts with p130(cas) and activates the expression of matrix metalloproteinases. Mol Cell Biol (2000) 1.16
Transgenic expression of COL1A1-chloramphenicol acetyltransferase fusion genes in bone: differential utilization of promoter elements in vivo and in cultured cells. Mol Cell Biol (1993) 1.12
Cell adhesion regulates pro-alpha 1(I) collagen mRNA stability and transcription in mouse fibroblasts. J Biol Chem (1991) 1.09
The nucleocytoplasmic shuttling protein CIZ reduces adult bone mass by inhibiting bone morphogenetic protein-induced bone formation. J Exp Med (2005) 1.08
The integrin-coupled signaling adaptor p130Cas suppresses Smad3 function in transforming growth factor-beta signaling. Mol Biol Cell (2008) 1.05
Context-dependent transcription: all politics is local. Gene (2003) 1.03
PTH-induced actin depolymerization increases mechanosensitive channel activity to enhance mechanically stimulated Ca2+ signaling in osteoblasts. J Bone Miner Res (2006) 1.01
Teriparatide: a review of its use in osteoporosis. Drugs (2008) 1.00
Promoter and intron 1 polymorphisms of COL1A1 interact to regulate transcription and susceptibility to osteoporosis. Hum Mol Genet (2009) 0.99
Negative regulation of bone morphogenetic protein/Smad signaling by Cas-interacting zinc finger protein in osteoblasts. J Biol Chem (2002) 0.99
Cloning and functional analysis of a family of nuclear matrix transcription factors (NP/NMP4) that regulate type I collagen expression in osteoblasts. J Bone Miner Res (2001) 0.98
Bone morphogenetic protein-2 enhances Wnt/beta-catenin signaling-induced osteoprotegerin expression. Genes Cells (2008) 0.96
Nuclear matrix proteins and osteoblast gene expression. J Bone Miner Res (1998) 0.96
Rat osteoblast and osteosarcoma nuclear matrix proteins bind with sequence specificity to the rat type I collagen promoter. Endocrinology (1997) 0.95
Disuse in adult male rats attenuates the bone anabolic response to a therapeutic dose of parathyroid hormone. J Appl Physiol (1985) (2006) 0.93
Nmp4/CIZ regulation of matrix metalloproteinase 13 (MMP-13) response to parathyroid hormone in osteoblasts. Am J Physiol Endocrinol Metab (2004) 0.93
Identification of a TAAT-containing motif required for high level expression of the COL1A1 promoter in differentiated osteoblasts of transgenic mice. J Biol Chem (1996) 0.92
Dose-response effects of intermittent PTH on cancellous bone in hindlimb unloaded rats. J Bone Miner Res (2007) 0.91
Parathyroid hormone-Smad3 axis exerts anti-apoptotic action and augments anabolic action of transforming growth factor beta in osteoblasts. J Biol Chem (2003) 0.90
Nmp4/CIZ suppresses parathyroid hormone-induced increases in trabecular bone. J Cell Physiol (2009) 0.90
Parathyroid hormone promotes the disassembly of cytoskeletal actin and myosin in cultured osteoblastic cells: mediation by cyclic AMP. J Cell Biochem (1991) 0.89
Is HMGB1 an osteocyte alarmin? J Cell Biochem (2008) 0.89
Interaction partners for human ZNF384/CIZ/NMP4--zyxin as a mediator for p130CAS signaling? Exp Cell Res (2006) 0.88
Dominant negative Bmp5 mutation reveals key role of BMPs in skeletal response to mechanical stimulation. BMC Dev Biol (2008) 0.86
Reduction of anabolic signals and alteration of osteoblast nuclear morphology in microgravity. J Cell Biochem (2006) 0.86
Cell cycling determines integrin-mediated adhesion in osteoblastic ROS 17/2.8 cells exposed to space-related conditions. FASEB J (2001) 0.85
Nmp4/CIZ contributes to fluid shear stress induced MMP-13 gene induction in osteoblasts. J Cell Biochem (2007) 0.85
PTH-responsive osteoblast nuclear matrix architectural transcription factor binds to the rat type I collagen promoter. J Cell Biochem (1998) 0.84
Influence of parathyroid hormone on bone cell ultrastructure. Clin Orthop Relat Res (1981) 0.83
NP/NMP4 transcription factors have distinct osteoblast nuclear matrix subdomains. J Cell Biochem (2000) 0.82
Two promoters control the mouse Nmp4/CIZ transcription factor gene. Gene (2005) 0.82
Parathyroid hormone activates adhesion in bone marrow stromal precursor cells. J Endocrinol (2004) 0.82
DNA binding and gene activation properties of the Nmp4 nuclear matrix transcription factors. J Biol Chem (2002) 0.79
Parathyroid hormone inhibits collagen synthesis and the activity of rat col1a1 transgenes mainly by a cAMP-mediated pathway in mouse calvariae. J Cell Biochem (2000) 0.79
Viewing problems in bone biology from the perspective of lineage identification. J Musculoskelet Neuronal Interact (2005) 0.78
Parathyroid hormone regulates the expression of the nuclear mitotic apparatus protein in the osteoblast-like cells, ROS 17/2.8. Bone (1998) 0.77
Assignment of Nmp4 to mouse chromosome 6 band F1 flanked by D6Mit134 and D6Mit255 using radiation hybrid mapping and fluorescence in situ hybridization. Cytogenet Cell Genet (2001) 0.77
Morphological changes in osteoblastic cells (MC3T3-E1) due to fluid shear stress: cellular damage by prolonged application of fluid shear stress. Tohoku J Exp Med (2000) 0.77
Identification of an osteoblastic silencer element in the first intron of the rat osteocalcin gene. Biochemistry (1996) 0.76
Lrp5 functions in bone to regulate bone mass. Nat Med (2011) 5.33
The Wnt co-receptor LRP5 is essential for skeletal mechanotransduction but not for the anabolic bone response to parathyroid hormone treatment. J Biol Chem (2006) 3.04
Control of bone mass and remodeling by PTH receptor signaling in osteocytes. PLoS One (2008) 2.96
Iron deficiency drives an autosomal dominant hypophosphatemic rickets (ADHR) phenotype in fibroblast growth factor-23 (Fgf23) knock-in mice. Proc Natl Acad Sci U S A (2011) 2.24
Inhibition of the serotonin (5-hydroxytryptamine) transporter reduces bone accrual during growth. Endocrinology (2004) 2.02
Sost downregulation and local Wnt signaling are required for the osteogenic response to mechanical loading. Bone (2011) 1.96
Sclerostin inhibition reverses skeletal fragility in an Lrp5-deficient mouse model of OPPG syndrome. Sci Transl Med (2013) 1.90
The effects of dynamic axial loading on the rat growth plate. J Bone Miner Res (2002) 1.82
Designing exercise regimens to increase bone strength. Exerc Sport Sci Rev (2003) 1.80
Dentin matrix protein 1 gene cis-regulation: use in osteocytes to characterize local responses to mechanical loading in vitro and in vivo. J Biol Chem (2005) 1.57
A model for mechanotransduction in bone cells: the load-bearing mechanosomes. J Cell Biochem (2003) 1.45
A comparison of mechanical properties derived from multiple skeletal sites in mice. J Biomech (2005) 1.27
Cellular accommodation and the response of bone to mechanical loading. J Biomech (2005) 1.25
Hyperactivation of p21ras and PI3K cooperate to alter murine and human neurofibromatosis type 1-haploinsufficient osteoclast functions. J Clin Invest (2006) 1.20
Mechanobiology of the skeleton. Sci Signal (2009) 1.17
HMGB1 is a bone-active cytokine. J Cell Physiol (2008) 1.13
Absence of Cx43 selectively from osteocytes enhances responsiveness to mechanical force in mice. J Orthop Res (2013) 1.09
Mechanotransduction in bone does not require a functional cyclooxygenase-2 (COX-2) gene. J Bone Miner Res (2004) 1.06
High-bone-mass-producing mutations in the Wnt signaling pathway result in distinct skeletal phenotypes. Bone (2011) 1.05
Mechanisms by which exercise improves bone strength. J Bone Miner Metab (2005) 1.04
Context-dependent transcription: all politics is local. Gene (2003) 1.03
Anabolic and catabolic regimens of human parathyroid hormone 1-34 elicit bone- and envelope-specific attenuation of skeletal effects in Sost-deficient mice. Endocrinology (2011) 1.02
The p85alpha subunit of class IA phosphatidylinositol 3-kinase regulates the expression of multiple genes involved in osteoclast maturation and migration. Mol Cell Biol (2008) 0.98
Rac1 mediates the osteoclast gains-in-function induced by haploinsufficiency of Nf1. Hum Mol Genet (2007) 0.98
An RNA-seq protocol to identify mRNA expression changes in mouse diaphyseal bone: applications in mice with bone property altering Lrp5 mutations. J Bone Miner Res (2013) 0.97
Exercise as an anabolic stimulus for bone. Curr Pharm Des (2004) 0.96
Late progression of renal pathology and cyst enlargement is reduced by rapamycin in a mouse model of nephronophthisis. Kidney Int (2009) 0.96
HMGB1 expression and release by bone cells. J Cell Physiol (2006) 0.95
Targeting the LRP5 pathway improves bone properties in a mouse model of osteogenesis imperfecta. J Bone Miner Res (2014) 0.93
Nmp4/CIZ regulation of matrix metalloproteinase 13 (MMP-13) response to parathyroid hormone in osteoblasts. Am J Physiol Endocrinol Metab (2004) 0.93
Mechanotransduction in bone tissue: The A214V and G171V mutations in Lrp5 enhance load-induced osteogenesis in a surface-selective manner. Bone (2012) 0.91
Bone mass and strength: phenotypic and genetic relationship to alcohol preference in P/NP and HAD/LAD rats. Alcohol Clin Exp Res (2005) 0.91
Nmp4/CIZ suppresses parathyroid hormone-induced increases in trabecular bone. J Cell Physiol (2009) 0.90
Is HMGB1 an osteocyte alarmin? J Cell Biochem (2008) 0.89
Inactivation of Lrp5 in osteocytes reduces young's modulus and responsiveness to the mechanical loading. Bone (2013) 0.88
Identification in human osteoarthritic chondrocytes of proteins binding to the novel regulatory site AGRE in the human matrix metalloprotease 13 proximal promoter. Arthritis Rheum (2006) 0.86
Mechanical stimulation and intermittent parathyroid hormone treatment induce disproportional osteogenic, geometric, and biomechanical effects in growing mouse bone. Calcif Tissue Int (2010) 0.85
Nmp4/CIZ contributes to fluid shear stress induced MMP-13 gene induction in osteoblasts. J Cell Biochem (2007) 0.85
The haploinsufficient hematopoietic microenvironment is critical to the pathological fracture repair in murine models of neurofibromatosis type 1. PLoS One (2011) 0.84
Two promoters control the mouse Nmp4/CIZ transcription factor gene. Gene (2005) 0.82
Nmp4/CIZ suppresses the response of bone to anabolic parathyroid hormone by regulating both osteoblasts and osteoclasts. Calcif Tissue Int (2011) 0.82
Nmp4/CIZ inhibits mechanically induced beta-catenin signaling activity in osteoblasts. J Cell Physiol (2010) 0.82
RAGE supports parathyroid hormone-induced gains in femoral trabecular bone. Am J Physiol Endocrinol Metab (2009) 0.82
Blockade of TNFR1 signaling: A role of oscillatory fluid shear stress in osteoblasts. J Cell Physiol (2011) 0.80
Immortalization and characterization of osteoblast cell lines generated from wild-type and Nmp4-null mouse bone marrow stromal cells using murine telomerase reverse transcriptase (mTERT). J Cell Physiol (2012) 0.80
DNA binding and gene activation properties of the Nmp4 nuclear matrix transcription factors. J Biol Chem (2002) 0.79
Signaling pathways involved in megakaryocyte-mediated proliferation of osteoblast lineage cells. J Cell Physiol (2015) 0.79
Nmp4/CIZ suppresses the parathyroid hormone anabolic window by restricting mesenchymal stem cell and osteoprogenitor frequency. Stem Cells Dev (2012) 0.79
In vivo axial loading of the mouse tibia. Methods Mol Biol (2015) 0.77
Conserved amino acid sequences confer nuclear localization upon the Prophet of Pit-1 pituitary transcription factor protein. Gene (2004) 0.77
Mechanosignaling in bone health, trauma and inflammation. Antioxid Redox Signal (2013) 0.76