Published in Am J Gastroenterol on June 11, 2007
Gene ontology analysis of GWA study data sets provides insights into the biology of bipolar disorder. Am J Hum Genet (2009) 5.98
Control of TH17 cells occurs in the small intestine. Nature (2011) 4.03
mTOR Inhibition Attenuates Dextran Sulfate Sodium-Induced Colitis by Suppressing T Cell Proliferation and Balancing TH1/TH17/Treg Profile. PLoS One (2016) 1.41
A novel Toll-like receptor 4 antagonist antibody ameliorates inflammation but impairs mucosal healing in murine colitis. Am J Physiol Gastrointest Liver Physiol (2009) 1.39
Evolving paradigms in the pathogenesis of IBD. J Gastroenterol (2009) 1.37
On the use of herbal medicines in management of inflammatory bowel diseases: a systematic review of animal and human studies. Dig Dis Sci (2008) 1.22
Curcumin: an orally bioavailable blocker of TNF and other pro-inflammatory biomarkers. Br J Pharmacol (2013) 1.21
A review of the efficacy of traditional Iranian medicine for inflammatory bowel disease. World J Gastroenterol (2010) 1.20
Matrix metalloproteinase 13 modulates intestinal epithelial barrier integrity in inflammatory diseases by activating TNF. EMBO Mol Med (2013) 1.17
Fusobacterium nucleatum infection of colonic cells stimulates MUC2 mucin and tumor necrosis factor alpha. Infect Immun (2011) 1.11
Nox enzymes and oxidative stress in the immunopathology of the gastrointestinal tract. Semin Immunopathol (2008) 1.11
Correlation of serum-soluble triggering receptor expressed on myeloid cells-1 with clinical disease activity in inflammatory bowel disease. Dig Dis Sci (2008) 1.10
Inflammatory bowel disease: Moving toward a stem cell-based therapy. World J Gastroenterol (2008) 1.10
Differential immune and genetic responses in rat models of Crohn's colitis and ulcerative colitis. Am J Physiol Gastrointest Liver Physiol (2010) 1.08
IL23R in the Swedish, Finnish, Hungarian and Italian populations: association with IBD and psoriasis, and linkage to celiac disease. BMC Med Genet (2009) 1.06
New serological biomarkers of inflammatory bowel disease. World J Gastroenterol (2008) 1.06
TGF-β limits IL-33 production and promotes the resolution of colitis through regulation of macrophage function. Eur J Immunol (2011) 1.04
Current view of the immunopathogenesis in inflammatory bowel disease and its implications for therapy. World J Gastroenterol (2008) 0.97
Anti-inflammatory effects of nicotine in obesity and ulcerative colitis. J Transl Med (2011) 0.96
Interleukin 10 inhibits interferon gamma- and tumor necrosis factor alpha-stimulated activation of NADPH oxidase 1 in human colonic epithelial cells and the mouse colon. J Gastroenterol (2009) 0.95
Metabolic alterations to the mucosal microbiota in inflammatory bowel disease. Inflamm Bowel Dis (2014) 0.93
Involvement of a Stat3 binding site in inflammation-induced enteric apelin expression. Am J Physiol Gastrointest Liver Physiol (2008) 0.88
Bifidobacterium breve attenuates murine dextran sodium sulfate-induced colitis and increases regulatory T cell responses. PLoS One (2014) 0.87
Effects of alanyl-glutamine dipeptide on the expression of colon-inflammatory mediators during the recovery phase of colitis induced by dextran sulfate sodium. Eur J Nutr (2012) 0.87
Interferon-γ induces expression of MHC class II on intestinal epithelial cells and protects mice from colitis. PLoS One (2014) 0.87
Promising effect of Magliasa, a traditional Iranian formula, on experimental colitis on the basis of biochemical and cellular findings. World J Gastroenterol (2013) 0.86
Sirolimus ameliorates inflammatory responses by switching the regulatory T/T helper type 17 profile in murine colitis. Immunology (2013) 0.85
Overexpression of translocator protein in inflammatory bowel disease: potential diagnostic and treatment value. Inflamm Bowel Dis (2010) 0.85
Overview of cytokines and nitric oxide involvement in immuno-pathogenesis of inflammatory bowel diseases. World J Gastrointest Pharmacol Ther (2016) 0.84
NADH oxidase-dependent CD39 expression by CD8(+) T cells modulates interferon gamma responses via generation of adenosine. Nat Commun (2015) 0.83
Hydrolysate from eggshell membrane ameliorates intestinal inflammation in mice. Int J Mol Sci (2014) 0.82
Tumor necrosis factor-α-induced colitis increases NADPH oxidase 1 expression, oxidative stress, and neutrophil recruitment in the colon: preventive effect of apocynin. Mediators Inflamm (2014) 0.82
Immune-related disorders in families of children with inflammatory bowel disease--a prospective cohort study. Ital J Pediatr (2011) 0.81
Attenuation of TNF-driven murine ileitis by intestinal expression of the viral immunomodulator CrmD. Mucosal Immunol (2010) 0.81
A subclass of acylated anti-inflammatory mediators usurp Toll-like receptor 2 to inhibit neutrophil recruitment through peroxisome proliferator-activated receptor gamma. Proc Natl Acad Sci U S A (2011) 0.81
Microbiotas from UC patients display altered metabolism and reduced ability of LAB to colonize mucus. Sci Rep (2013) 0.81
Characterization of the effects of cross-linking of macrophage CD44 associated with increased phagocytosis of apoptotic PMN. PLoS One (2012) 0.80
Amino acids exhibit anti-inflammatory effects in human monocytic leukemia cell line, THP-1 cells. Inflamm Res (2011) 0.80
Mer receptor tyrosine kinase mediates both tethering and phagocytosis of apoptotic cells. Cell Death Dis (2015) 0.80
Indole compounds may be promising medicines for ulcerative colitis. J Gastroenterol (2016) 0.78
Protective effects of lithium on acetic acid-induced colitis in rats. Dig Dis Sci (2008) 0.78
Anti-inflammatory effects of the Chinese herbal formula FAHF-2 in experimental and human IBD. Inflamm Bowel Dis (2014) 0.78
The role of Klebsiella in Crohn's disease with a potential for the use of antimicrobial measures. Int J Rheumatol (2013) 0.78
Extracellular ATP mediates inflammatory responses in colitis via P2 × 7 receptor signaling. Sci Rep (2016) 0.76
Role of Retinoic Acid-Metabolizing Cytochrome P450s, CYP26, in Inflammation and Cancer. Adv Pharmacol (2015) 0.76
Cytokine profiles in peripheral blood of children and adults with Crohn disease. J Pediatr Gastroenterol Nutr (2012) 0.76
Treatment of Crohn's disease with colony-stimulating factors: An overview. Ther Clin Risk Manag (2008) 0.76
Sclerosing mesenteritis successfully treated with a TNF antagonist. BMJ Case Rep (2010) 0.75
Uridine Ameliorates Dextran Sulfate Sodium (DSS)-Induced Colitis in Mice. Sci Rep (2017) 0.75
Orally administered extract from Prunella vulgaris attenuates spontaneous colitis in mdr1a(-/-) mice. World J Gastrointest Pharmacol Ther (2015) 0.75
Anti-inflammatory effects of mannanase-hydrolyzed copra meal in a porcine model of colitis. J Vet Med Sci (2014) 0.75
LPS-Stimulated Whole Blood Cytokine Production Is Not Related to Disease Behavior in Patients with Quiescent Crohn's Disease. PLoS One (2015) 0.75
Tanshinone IIA Protects against Dextran Sulfate Sodium- (DSS-) Induced Colitis in Mice by Modulation of Neutrophil Infiltration and Activation. Oxid Med Cell Longev (2016) 0.75
Transcriptional modulation of pattern recognition receptors in chronic colitis in mice is accompanied with Th1 and Th17 response. Biochem Biophys Rep (2017) 0.75
Anti-interleukin-12 antibody for active Crohn's disease. N Engl J Med (2004) 7.93
Mucus enhances gut homeostasis and oral tolerance by delivering immunoregulatory signals. Science (2013) 3.74
Crosstalk between B lymphocytes, microbiota and the intestinal epithelium governs immunity versus metabolism in the gut. Nat Med (2011) 3.06
Incidence and importance of antibody responses to infliximab after maintenance or episodic treatment in Crohn's disease. Clin Gastroenterol Hepatol (2004) 2.99
Toll-like receptors on tumor cells facilitate evasion of immune surveillance. Cancer Res (2005) 2.91
Development of an internet-based cohort of patients with inflammatory bowel diseases (CCFA Partners): methodology and initial results. Inflamm Bowel Dis (2012) 2.23
Chromoendoscopy-targeted biopsies are superior to standard colonoscopic surveillance for detecting dysplasia in inflammatory bowel disease patients: a prospective endoscopic trial. Am J Gastroenterol (2008) 2.16
The incidence and management of infusion reactions to infliximab: a large center experience. Am J Gastroenterol (2003) 2.06
Interleukin 10 suppresses Th17 cytokines secreted by macrophages and T cells. Eur J Immunol (2008) 2.05
The expression and function of costimulatory molecules B7H and B7-H1 on colonic epithelial cells. Gastroenterology (2004) 2.02
Lung dendritic cells induce migration of protective T cells to the gastrointestinal tract. J Exp Med (2013) 1.99
The natural history of milk allergy in an observational cohort. J Allergy Clin Immunol (2012) 1.96
Characterization of interleukin-17-producing regulatory T cells in inflamed intestinal mucosa from patients with inflammatory bowel diseases. Gastroenterology (2010) 1.92
Toll-like receptor signaling in small intestinal epithelium promotes B-cell recruitment and IgA production in lamina propria. Gastroenterology (2008) 1.89
Tacrolimus for the treatment of fistulas in patients with Crohn's disease: a randomized, placebo-controlled trial. Gastroenterology (2003) 1.70
A phase I study of visilizumab, a humanized anti-CD3 monoclonal antibody, in severe steroid-refractory ulcerative colitis. Gastroenterology (2007) 1.64
American gastroenterological association consensus development conference on the use of biologics in the treatment of inflammatory bowel disease, June 21-23, 2006. Gastroenterology (2007) 1.60
Monoclonal antibodies, immunogenicity, and associated infusion reactions. Mt Sinai J Med (2005) 1.57
Listeria monocytogenes promotes tumor growth via tumor cell toll-like receptor 2 signaling. Cancer Res (2007) 1.53
Accumulation of peripheral autoreactive B cells in the absence of functional human regulatory T cells. Blood (2012) 1.53
Anti-CD3 antibody visilizumab is not effective in patients with intravenous corticosteroid-refractory ulcerative colitis. Gut (2010) 1.53
A genome-wide scan of Ashkenazi Jewish Crohn's disease suggests novel susceptibility loci. PLoS Genet (2012) 1.52
IRF-8/interferon (IFN) consensus sequence-binding protein is involved in Toll-like receptor (TLR) signaling and contributes to the cross-talk between TLR and IFN-gamma signaling pathways. J Biol Chem (2006) 1.52
Recent understanding of IBD pathogenesis: implications for future therapies. Inflamm Bowel Dis (2006) 1.51
The cytomegalovirus-encoded chemokine receptor US28 promotes intestinal neoplasia in transgenic mice. J Clin Invest (2010) 1.50
Expansion of CD8+ T cells with regulatory function after interaction with intestinal epithelial cells. Gastroenterology (2002) 1.49
CD4+NKG2D+ T cells in Crohn's disease mediate inflammatory and cytotoxic responses through MICA interactions. Gastroenterology (2007) 1.47
Defects in CD8+ regulatory T cells in the lamina propria of patients with inflammatory bowel disease. J Immunol (2005) 1.43
Oral tolerance and its relation to food hypersensitivities. J Allergy Clin Immunol (2005) 1.42
A novel Toll-like receptor 4 antagonist antibody ameliorates inflammation but impairs mucosal healing in murine colitis. Am J Physiol Gastrointest Liver Physiol (2009) 1.39
Inflamed lymphatic endothelium suppresses dendritic cell maturation and function via Mac-1/ICAM-1-dependent mechanism. J Immunol (2009) 1.33
Failure to induce oral tolerance to a soluble protein in patients with inflammatory bowel disease. Gastroenterology (2004) 1.33
Pathogenesis and treatment of gastrointestinal disease in antibody deficiency syndromes. J Allergy Clin Immunol (2009) 1.30
Constitutive activation of epithelial TLR4 augments inflammatory responses to mucosal injury and drives colitis-associated tumorigenesis. Inflamm Bowel Dis (2010) 1.28
Epstein-Barr virus-induced gene 3 negatively regulates IL-17, IL-22 and RORgamma t. Eur J Immunol (2008) 1.26
Induction of mucosal tolerance in Peyer's patch-deficient, ligated small bowel loops. J Clin Invest (2005) 1.25
Immunologic features of infants with milk or egg allergy enrolled in an observational study (Consortium of Food Allergy Research) of food allergy. J Allergy Clin Immunol (2010) 1.25
Sublingual immunotherapy for peanut allergy: a randomized, double-blind, placebo-controlled multicenter trial. J Allergy Clin Immunol (2013) 1.24
Transcription factor IRF8 directs a silencing programme for TH17 cell differentiation. Nat Commun (2011) 1.23
Epithelial: lamina propria lymphocyte interactions promote epithelial cell differentiation. Gastroenterology (2007) 1.23
Expression of nonclassical class I molecules by intestinal epithelial cells. Inflamm Bowel Dis (2007) 1.21
Characterization of immunologic defects in patients with common variable immunodeficiency (CVID) with intestinal disease. Inflamm Bowel Dis (2011) 1.21
Regulatory T cells: peace keepers in the gut. Inflamm Bowel Dis (2004) 1.17
CD4 T cells activated in the mesenteric lymph node mediate gastrointestinal food allergy in mice. Am J Physiol Gastrointest Liver Physiol (2007) 1.17
Crohn disease: frequency and nature of CARD15 mutations in Ashkenazi and Sephardi/Oriental Jewish families. Am J Hum Genet (2004) 1.17
AP-1 activated by toll-like receptors regulates expression of IL-23 p19. J Biol Chem (2009) 1.17
Epithelia: lymphocyte interactions in the gut. Immunol Rev (2007) 1.15
Thymic stromal lymphopoietin is required for gastrointestinal allergy but not oral tolerance. Gastroenterology (2010) 1.12
MicroRNA-7 modulates CD98 expression during intestinal epithelial cell differentiation. J Biol Chem (2009) 1.12
Ubiquitin-dependent degradation of interferon regulatory factor-8 mediated by Cbl down-regulates interleukin-12 expression. J Biol Chem (2005) 1.11
Evaluation of 22 genetic variants with Crohn's disease risk in the Ashkenazi Jewish population: a case-control study. BMC Med Genet (2011) 1.10
Diagnosis and treatment of gastrointestinal disorders in patients with primary immunodeficiency. Clin Gastroenterol Hepatol (2013) 1.09
Activation of CD8+ regulatory T cells by human placental trophoblasts. J Immunol (2005) 1.09
Intestinal epithelial cells from inflammatory bowel disease patients preferentially stimulate CD4+ T cells to proliferate and secrete interferon-gamma. Am J Physiol Gastrointest Liver Physiol (2007) 1.08
Gastrointestinal manifestations in primary immune disorders. Inflamm Bowel Dis (2010) 1.08
The kinetics and pattern of tracheal allograft re-epithelialization. Am J Respir Cell Mol Biol (2003) 1.07
Complex formation of the interferon (IFN) consensus sequence-binding protein with IRF-1 is essential for murine macrophage IFN-gamma-induced iNOS gene expression. J Biol Chem (2002) 1.05
High levels of Crohn's disease-associated anti-microbial antibodies are present and independent of colitis in chronic granulomatous disease. Clin Immunol (2010) 1.01
Notch-1 signaling regulates intestinal epithelial barrier function, through interaction with CD4+ T cells, in mice and humans. Gastroenterology (2010) 1.00
Normal response to vaccines in inflammatory bowel disease patients treated with thiopurines. Inflamm Bowel Dis (2011) 0.99
Orthotopic tracheal transplantation in the murine model. Transplantation (2002) 0.98
Allergic sensitization can be induced via multiple physiologic routes in an adjuvant-dependent manner. J Allergy Clin Immunol (2011) 0.98
Activation of a unique population of CD8(+) T cells by intestinal epithelial cells. Ann N Y Acad Sci (2004) 0.95
Metabolic alterations to the mucosal microbiota in inflammatory bowel disease. Inflamm Bowel Dis (2014) 0.93
A role for the epidermal growth factor receptor signaling in development of intestinal serrated polyps in mice and humans. Gastroenterology (2012) 0.92
Prospective randomized open-label multicenter phase I/II dose escalation trial of visilizumab (HuM291) in severe steroid-refractory ulcerative colitis. Inflamm Bowel Dis (2010) 0.92
Serum protein profiling in patients with inflammatory bowel diseases using selective solid-phase bulk extraction, matrix-assisted laser desorption/ionization time-of-flight mass spectrometry and chemometric data analysis. Rapid Commun Mass Spectrom (2007) 0.91
Orthotopic tracheal allografts undergo reepithelialization with recipient-derived epithelium. Arch Otolaryngol Head Neck Surg (2003) 0.90
A functional role for CCR6 on proallergic T cells in the gastrointestinal tract. Gastroenterology (2009) 0.89
Mucosal epithelium in health and disease. Curr Mol Med (2005) 0.88
Evidence for a genetic defect in oral tolerance induction in inflammatory bowel disease. Inflamm Bowel Dis (2006) 0.88
Non-classical MHC class I molecules on intestinal epithelial cells: mediators of mucosal crosstalk. Immunol Rev (2005) 0.87
Expression of the chemokine binding protein M3 promotes marked changes in the accumulation of specific leukocytes subsets within the intestine. Gastroenterology (2009) 0.87
Oral tolerance and inflammatory bowel disease. Curr Opin Gastroenterol (2005) 0.87
Defect in CEACAM family member expression in Crohn's disease IECs is regulated by the transcription factor SOX9. Inflamm Bowel Dis (2009) 0.87
Can we produce true tolerance in patients with food allergy? J Allergy Clin Immunol (2013) 0.86
Allergen-IgE complexes trigger CD23-dependent CCL20 release from human intestinal epithelial cells. Gastroenterology (2007) 0.86
New proteomic approaches for biomarker discovery in inflammatory bowel disease. Inflamm Bowel Dis (2010) 0.85
Current status of monoclonal antibody therapy for the treatment of inflammatory bowel disease. Expert Rev Clin Immunol (2010) 0.85
A multicenter retrospective experience of infliximab in Crohn's disease patients: infusion reaction rates and treatment persistency. Gastroenterol Hepatol (N Y) (2007) 0.83
Mucosal immunology of tolerance and allergy in the gastrointestinal tract. Immunol Res (2012) 0.83
Enhanced oral tolerance in transgenic mice with hepatocyte secretion of IL-10. J Immunol (2005) 0.82
Immunopathogenesis of inflammatory bowel disease. Curr Opin Gastroenterol (2002) 0.82
Immunomodulatory roles of the carcinoembryonic antigen family of glycoproteins. Ann N Y Acad Sci (2006) 0.81
Failure to induce oral tolerance in Crohn's and ulcerative colitis patients: possible genetic risk. Ann N Y Acad Sci (2004) 0.81
Transforming growth factor β signaling controls activities of human intestinal CD8(+)T suppressor cells. Gastroenterology (2012) 0.81
Meeting summary: Signal transduction pathways in immune and inflammatory cells. November 30-December 3, 2000, Amelia Island, Florida, U.S.A. Inflamm Bowel Dis (2003) 0.81
Use of GM-CSF in the treatment of colitis associated with chronic granulomatous disease. J Allergy Clin Immunol (2005) 0.81
The real meaning of translational research. Gastroenterology (2002) 0.80
Mitochondria influence Fas expression in gp120-induced apoptosis of neuronal cells. Int J Neurosci (2009) 0.80
Current status of monoclonal antibody therapy for the treatment of inflammatory bowel disease: an update. Expert Rev Clin Immunol (2013) 0.79
Extracorporeal photopheresis for the treatment of refractory Crohn's disease: results of an open-label pilot study. Inflamm Bowel Dis (2009) 0.79
Anti-inflammatory effects of the Chinese herbal formula FAHF-2 in experimental and human IBD. Inflamm Bowel Dis (2014) 0.78
Lymphoepithelial interactions: a new paradigm. Ann N Y Acad Sci (2009) 0.78
Dead on arrival: understanding the failure of CTLA4-immunoglobulin therapy in inflammatory bowel disease. Gastroenterology (2012) 0.77
Working out mechanisms of controlled/physiologic inflammation in the GI tract. Immunol Res (2012) 0.77
Redefining autoimmunity. Gastroenterology (2003) 0.77
A novel approach to the treatment of ulcerative colitis: is it kosher? Gastroenterology (2005) 0.77
Potential non-T cells source of interleukin-4 in food allergy. Pediatr Allergy Immunol (2014) 0.76
Natural killer T cells in mucosal homeostasis. Ann N Y Acad Sci (2004) 0.76