Published in Inflamm Bowel Dis on April 01, 2014
Antimicrobial Therapy for Ulcerative Colitis (UC) (UC) | NCT03986996
Functional Characterization of Inflammatory Bowel Disease-Associated Gut Dysbiosis in Gnotobiotic Mice. Cell Mol Gastroenterol Hepatol (2016) 1.05
Effects of high doses of vitamin D3 on mucosa-associated gut microbiome vary between regions of the human gastrointestinal tract. Eur J Nutr (2015) 0.84
Metagenomic analysis of microbiome in colon tissue from subjects with inflammatory bowel diseases reveals interplay of viruses and bacteria. Inflamm Bowel Dis (2015) 0.82
Inferred metagenomic comparison of mucosal and fecal microbiota from individuals undergoing routine screening colonoscopy reveals similar differences observed during active inflammation. Gut Microbes (2015) 0.81
Functional Metagenomics of the Bronchial Microbiome in COPD. PLoS One (2015) 0.79
Microbiome associations of therapeutic enteral nutrition. Nutrients (2014) 0.79
Evaluation of the Microbial Diversity in Amyotrophic Lateral Sclerosis Using High-Throughput Sequencing. Front Microbiol (2016) 0.78
Composition and function of the pediatric colonic mucosal microbiome in untreated patients with ulcerative colitis. Gut Microbes (2016) 0.77
Microbiome in chronic obstructive pulmonary disease. Ann Transl Med (2017) 0.76
Amphibian gut microbiota shifts differentially in community structure but converges on habitat-specific predicted functions. Nat Commun (2016) 0.75
PNPLA3 148M Carriers with Inflammatory Bowel Diseases Have Higher Susceptibility to Hepatic Steatosis and Higher Liver Enzymes. Inflamm Bowel Dis (2016) 0.75
Crossover Subsets of CD4(+) T Lymphocytes in the Intestinal Lamina Propria of Patients with Crohn's Disease and Ulcerative Colitis. Dig Dis Sci (2017) 0.75
QIIME allows analysis of high-throughput community sequencing data. Nat Methods (2010) 85.34
Greengenes, a chimera-checked 16S rRNA gene database and workbench compatible with ARB. Appl Environ Microbiol (2006) 57.72
Search and clustering orders of magnitude faster than BLAST. Bioinformatics (2010) 51.97
Structure, function and diversity of the healthy human microbiome. Nature (2012) 30.40
Molecular-phylogenetic characterization of microbial community imbalances in human inflammatory bowel diseases. Proc Natl Acad Sci U S A (2007) 20.60
Global patterns of 16S rRNA diversity at a depth of millions of sequences per sample. Proc Natl Acad Sci U S A (2010) 19.48
Human gut microbiome viewed across age and geography. Nature (2012) 19.31
Ultra-high-throughput microbial community analysis on the Illumina HiSeq and MiSeq platforms. ISME J (2012) 16.84
Metagenomic biomarker discovery and explanation. Genome Biol (2011) 11.29
Predictive functional profiling of microbial communities using 16S rRNA marker gene sequences. Nat Biotechnol (2013) 11.05
Reduced diversity of faecal microbiota in Crohn's disease revealed by a metagenomic approach. Gut (2005) 10.95
Interactions between the microbiota and the immune system. Science (2012) 10.45
The microbial metabolites, short-chain fatty acids, regulate colonic Treg cell homeostasis. Science (2013) 8.53
Mucosal flora in inflammatory bowel disease. Gastroenterology (2002) 8.42
Genetics and pathogenesis of inflammatory bowel disease. Nature (2011) 7.79
Dysfunction of the intestinal microbiome in inflammatory bowel disease and treatment. Genome Biol (2012) 5.66
Reduction in diversity of the colonic mucosa associated bacterial microflora in patients with active inflammatory bowel disease. Gut (2004) 5.32
Metagenomic systems biology of the human gut microbiome reveals topological shifts associated with obesity and inflammatory bowel disease. Proc Natl Acad Sci U S A (2011) 4.53
The gut microbiota in IBD. Nat Rev Gastroenterol Hepatol (2012) 3.88
The microbiome in infectious disease and inflammation. Annu Rev Immunol (2012) 3.76
The Firmicutes/Bacteroidetes ratio of the human microbiota changes with age. BMC Microbiol (2009) 3.58
Interactions between the host innate immune system and microbes in inflammatory bowel disease. Gastroenterology (2011) 2.90
Control of pathogens and pathobionts by the gut microbiota. Nat Immunol (2013) 2.84
Twin study indicates loss of interaction between microbiota and mucosa of patients with ulcerative colitis. Gastroenterology (2011) 2.52
Bacterial biogeography of the human digestive tract. Sci Rep (2011) 2.18
The genome of th17 cell-inducing segmented filamentous bacteria reveals extensive auxotrophy and adaptations to the intestinal environment. Cell Host Microbe (2011) 1.97
Analysis of bacterial bowel communities of IBD patients: what has it revealed? Inflamm Bowel Dis (2008) 1.72
The immune response in inflammatory bowel disease. Am J Gastroenterol (2007) 1.67
Mucin function in inflammatory bowel disease: an update. J Clin Gastroenterol (2013) 1.55
Microbiota of de-novo pediatric IBD: increased Faecalibacterium prausnitzii and reduced bacterial diversity in Crohn's but not in ulcerative colitis. Am J Gastroenterol (2012) 1.54
IL-22-producing CD4+ cells are depleted in actively inflamed colitis tissue. Mucosal Immunol (2013) 1.29
Indeterminate colitis. Inflamm Bowel Dis (2003) 1.08
Host-microbiota interactions in inflammatory bowel disease. Gut Microbes (2012) 1.05
Longitudinal analyses of gut mucosal microbiotas in ulcerative colitis in relation to patient age and disease severity and duration. J Clin Microbiol (2012) 1.04
Anti-interleukin-12 antibody for active Crohn's disease. N Engl J Med (2004) 7.93
Tryptophan catabolism by indoleamine 2,3-dioxygenase 1 alters the balance of TH17 to regulatory T cells in HIV disease. Sci Transl Med (2010) 4.07
Mucus enhances gut homeostasis and oral tolerance by delivering immunoregulatory signals. Science (2013) 3.74
Histologic inflammation is a risk factor for progression to colorectal neoplasia in ulcerative colitis: a cohort study. Gastroenterology (2007) 3.39
Crosstalk between B lymphocytes, microbiota and the intestinal epithelium governs immunity versus metabolism in the gut. Nat Med (2011) 3.06
Incidence and importance of antibody responses to infliximab after maintenance or episodic treatment in Crohn's disease. Clin Gastroenterol Hepatol (2004) 2.99
Toll-like receptors on tumor cells facilitate evasion of immune surveillance. Cancer Res (2005) 2.91
Receptor activation alters inner surface potential during phagocytosis. Science (2006) 2.69
B7x: a widely expressed B7 family member that inhibits T cell activation. Proc Natl Acad Sci U S A (2003) 2.66
Chitinase and Fizz family members are a generalized feature of nematode infection with selective upregulation of Ym1 and Fizz1 by antigen-presenting cells. Infect Immun (2005) 2.51
Proteases in parasitic diseases. Annu Rev Pathol (2006) 2.26
Development of an internet-based cohort of patients with inflammatory bowel diseases (CCFA Partners): methodology and initial results. Inflamm Bowel Dis (2012) 2.23
Chromoendoscopy-targeted biopsies are superior to standard colonoscopic surveillance for detecting dysplasia in inflammatory bowel disease patients: a prospective endoscopic trial. Am J Gastroenterol (2008) 2.16
The incidence and management of infusion reactions to infliximab: a large center experience. Am J Gastroenterol (2003) 2.06
Interleukin 10 suppresses Th17 cytokines secreted by macrophages and T cells. Eur J Immunol (2008) 2.05
The expression and function of costimulatory molecules B7H and B7-H1 on colonic epithelial cells. Gastroenterology (2004) 2.02
Lung dendritic cells induce migration of protective T cells to the gastrointestinal tract. J Exp Med (2013) 1.99
The natural history of milk allergy in an observational cohort. J Allergy Clin Immunol (2012) 1.96
Characterization of interleukin-17-producing regulatory T cells in inflamed intestinal mucosa from patients with inflammatory bowel diseases. Gastroenterology (2010) 1.92
Toll-like receptor signaling in small intestinal epithelium promotes B-cell recruitment and IgA production in lamina propria. Gastroenterology (2008) 1.89
Chemoprevention of colorectal neoplasia in ulcerative colitis: the effect of 6-mercaptopurine. Clin Gastroenterol Hepatol (2005) 1.79
Tacrolimus for the treatment of fistulas in patients with Crohn's disease: a randomized, placebo-controlled trial. Gastroenterology (2003) 1.70
The immune response in inflammatory bowel disease. Am J Gastroenterol (2007) 1.67
Perioperative cognitive decline in the aging population. Mayo Clin Proc (2011) 1.66
A phase I study of visilizumab, a humanized anti-CD3 monoclonal antibody, in severe steroid-refractory ulcerative colitis. Gastroenterology (2007) 1.64
American gastroenterological association consensus development conference on the use of biologics in the treatment of inflammatory bowel disease, June 21-23, 2006. Gastroenterology (2007) 1.60
The role of postoperative analgesia in delirium and cognitive decline in elderly patients: a systematic review. Anesth Analg (2006) 1.58
Placental transfer of anti-tumor necrosis factor agents in pregnant patients with inflammatory bowel disease. Clin Gastroenterol Hepatol (2012) 1.57
Monoclonal antibodies, immunogenicity, and associated infusion reactions. Mt Sinai J Med (2005) 1.57
Listeria monocytogenes promotes tumor growth via tumor cell toll-like receptor 2 signaling. Cancer Res (2007) 1.53
Accumulation of peripheral autoreactive B cells in the absence of functional human regulatory T cells. Blood (2012) 1.53
Anti-CD3 antibody visilizumab is not effective in patients with intravenous corticosteroid-refractory ulcerative colitis. Gut (2010) 1.53
A genome-wide scan of Ashkenazi Jewish Crohn's disease suggests novel susceptibility loci. PLoS Genet (2012) 1.52
Postoperative delirium: the importance of pain and pain management. Anesth Analg (2006) 1.52
Therapeutic helminth infection of macaques with idiopathic chronic diarrhea alters the inflammatory signature and mucosal microbiota of the colon. PLoS Pathog (2012) 1.52
IRF-8/interferon (IFN) consensus sequence-binding protein is involved in Toll-like receptor (TLR) signaling and contributes to the cross-talk between TLR and IFN-gamma signaling pathways. J Biol Chem (2006) 1.52
Recent understanding of IBD pathogenesis: implications for future therapies. Inflamm Bowel Dis (2006) 1.51
The cytomegalovirus-encoded chemokine receptor US28 promotes intestinal neoplasia in transgenic mice. J Clin Invest (2010) 1.50
Preoperative electrocardiogram abnormalities do not predict postoperative cardiac complications in geriatric surgical patients. J Am Geriatr Soc (2002) 1.49
Expansion of CD8+ T cells with regulatory function after interaction with intestinal epithelial cells. Gastroenterology (2002) 1.49
CD4+NKG2D+ T cells in Crohn's disease mediate inflammatory and cytotoxic responses through MICA interactions. Gastroenterology (2007) 1.47
Defects in CD8+ regulatory T cells in the lamina propria of patients with inflammatory bowel disease. J Immunol (2005) 1.43
IL-22+ CD4+ T cells are associated with therapeutic trichuris trichiura infection in an ulcerative colitis patient. Sci Transl Med (2010) 1.42
Oral tolerance and its relation to food hypersensitivities. J Allergy Clin Immunol (2005) 1.42
A novel Toll-like receptor 4 antagonist antibody ameliorates inflammation but impairs mucosal healing in murine colitis. Am J Physiol Gastrointest Liver Physiol (2009) 1.39
Inflamed lymphatic endothelium suppresses dendritic cell maturation and function via Mac-1/ICAM-1-dependent mechanism. J Immunol (2009) 1.33
Failure to induce oral tolerance to a soluble protein in patients with inflammatory bowel disease. Gastroenterology (2004) 1.33
Pathogenesis and treatment of gastrointestinal disease in antibody deficiency syndromes. J Allergy Clin Immunol (2009) 1.30
Constitutive activation of epithelial TLR4 augments inflammatory responses to mucosal injury and drives colitis-associated tumorigenesis. Inflamm Bowel Dis (2010) 1.28
Epstein-Barr virus-induced gene 3 negatively regulates IL-17, IL-22 and RORgamma t. Eur J Immunol (2008) 1.26
Cyclosporine and infliximab as rescue therapy for each other in patients with steroid-refractory ulcerative colitis. Clin Gastroenterol Hepatol (2008) 1.25
Induction of mucosal tolerance in Peyer's patch-deficient, ligated small bowel loops. J Clin Invest (2005) 1.25
Immunologic features of infants with milk or egg allergy enrolled in an observational study (Consortium of Food Allergy Research) of food allergy. J Allergy Clin Immunol (2010) 1.25
Global analysis of the sporulation pathway of Clostridium difficile. PLoS Genet (2013) 1.24
Sublingual immunotherapy for peanut allergy: a randomized, double-blind, placebo-controlled multicenter trial. J Allergy Clin Immunol (2013) 1.24
Transcription factor IRF8 directs a silencing programme for TH17 cell differentiation. Nat Commun (2011) 1.23
Epithelial: lamina propria lymphocyte interactions promote epithelial cell differentiation. Gastroenterology (2007) 1.23
Expression of nonclassical class I molecules by intestinal epithelial cells. Inflamm Bowel Dis (2007) 1.21
Characterization of immunologic defects in patients with common variable immunodeficiency (CVID) with intestinal disease. Inflamm Bowel Dis (2011) 1.21
Increases in P-wave dispersion predict postoperative atrial fibrillation after coronary artery bypass graft surgery. Anesth Analg (2004) 1.19
Regulatory T cells: peace keepers in the gut. Inflamm Bowel Dis (2004) 1.17
CD4 T cells activated in the mesenteric lymph node mediate gastrointestinal food allergy in mice. Am J Physiol Gastrointest Liver Physiol (2007) 1.17
AP-1 activated by toll-like receptors regulates expression of IL-23 p19. J Biol Chem (2009) 1.17
Crohn disease: frequency and nature of CARD15 mutations in Ashkenazi and Sephardi/Oriental Jewish families. Am J Hum Genet (2004) 1.17
Common beta-lactamases inhibit bacterial biofilm formation. Mol Microbiol (2005) 1.16
Epithelia: lymphocyte interactions in the gut. Immunol Rev (2007) 1.15
Using Evernote as an electronic lab notebook in a translational science laboratory. J Lab Autom (2012) 1.14
Tissue-specific expression of B7x protects from CD4 T cell-mediated autoimmunity. J Exp Med (2011) 1.14
Delineation of diverse macrophage activation programs in response to intracellular parasites and cytokines. PLoS Negl Trop Dis (2010) 1.14
Upregulation of retinal dehydrogenase 2 in alternatively activated macrophages during retinoid-dependent type-2 immunity to helminth infection in mice. PLoS Pathog (2012) 1.13
Preferential HIV infection of CCR6+ Th17 cells is associated with higher levels of virus receptor expression and lack of CCR5 ligands. J Virol (2013) 1.12
Thymic stromal lymphopoietin is required for gastrointestinal allergy but not oral tolerance. Gastroenterology (2010) 1.12
An Update on Postoperative Cognitive Dysfunction. Adv Anesth (2010) 1.12
MicroRNA-7 modulates CD98 expression during intestinal epithelial cell differentiation. J Biol Chem (2009) 1.12
Ubiquitin-dependent degradation of interferon regulatory factor-8 mediated by Cbl down-regulates interleukin-12 expression. J Biol Chem (2005) 1.11
Correlating cellular and molecular signatures of mucosal immunity that distinguish HIV controllers from noncontrollers. Blood (2010) 1.11
Prognostic significance of postoperative in-hospital complications in elderly patients. I. Long-term survival. Anesth Analg (2003) 1.11
Small bowel resection rates in Crohn's disease and the indication for surgery over time: experience from a large tertiary care center. Inflamm Bowel Dis (2010) 1.11
Evaluation of 22 genetic variants with Crohn's disease risk in the Ashkenazi Jewish population: a case-control study. BMC Med Genet (2011) 1.10
Full-length-enriched cDNA libraries from Echinococcus granulosus contain separate populations of oligo-capped and trans-spliced transcripts and a high level of predicted signal peptide sequences. Mol Biochem Parasitol (2002) 1.09
Diagnosis and treatment of gastrointestinal disorders in patients with primary immunodeficiency. Clin Gastroenterol Hepatol (2013) 1.09
Cytokine-dependent inflammatory cell recruitment patterns in the peritoneal cavity of mice exposed to the parasitic nematode Brugia malayi. Med Microbiol Immunol (2002) 1.09
Activation of CD8+ regulatory T cells by human placental trophoblasts. J Immunol (2005) 1.09
A small-molecule inhibitor of T. gondii motility induces the posttranslational modification of myosin light chain-1 and inhibits myosin motor activity. PLoS Pathog (2010) 1.08
Intestinal epithelial cells from inflammatory bowel disease patients preferentially stimulate CD4+ T cells to proliferate and secrete interferon-gamma. Am J Physiol Gastrointest Liver Physiol (2007) 1.08
Gastrointestinal manifestations in primary immune disorders. Inflamm Bowel Dis (2010) 1.08
The kinetics and pattern of tracheal allograft re-epithelialization. Am J Respir Cell Mol Biol (2003) 1.07
Helminthic therapy: improving mucosal barrier function. Trends Parasitol (2012) 1.06
Complex formation of the interferon (IFN) consensus sequence-binding protein with IRF-1 is essential for murine macrophage IFN-gamma-induced iNOS gene expression. J Biol Chem (2002) 1.05
Gene expression patterns of dengue virus-infected children from nicaragua reveal a distinct signature of increased metabolism. PLoS Negl Trop Dis (2010) 1.05
Histologic assessment of right atrial appendage myocardium in patients with atrial fibrillation after coronary artery bypass graft surgery. Cardiology (2006) 1.05
Endoscopic imaging: How far are we from real-time histology? World J Gastrointest Endosc (2011) 1.04
MicroRNA-33-dependent regulation of macrophage metabolism directs immune cell polarization in atherosclerosis. J Clin Invest (2015) 1.03
High levels of Crohn's disease-associated anti-microbial antibodies are present and independent of colitis in chronic granulomatous disease. Clin Immunol (2010) 1.01