Published in Curr Opin Struct Biol on June 15, 2007
A three-dimensional view of the molecular machinery of RNA interference. Nature (2009) 6.31
SF1 and SF2 helicases: family matters. Curr Opin Struct Biol (2010) 3.79
RNA helicases at work: binding and rearranging. Trends Biochem Sci (2011) 2.42
The crystal structure of Mtr4 reveals a novel arch domain required for rRNA processing. EMBO J (2010) 2.25
Powering through ribosome assembly. RNA (2009) 2.19
ATP hydrolysis is required for DEAD-box protein recycling but not for duplex unwinding. Proc Natl Acad Sci U S A (2008) 2.14
Kinetic redistribution of native and misfolded RNAs by a DEAD-box chaperone. Nature (2007) 2.00
Insights into RNA unwinding and ATP hydrolysis by the flavivirus NS3 protein. EMBO J (2008) 1.99
A long noncoding RNA protects the heart from pathological hypertrophy. Nature (2014) 1.96
DEAD-box proteins can completely separate an RNA duplex using a single ATP. Proc Natl Acad Sci U S A (2008) 1.72
The mRNA export protein DBP5 binds RNA and the cytoplasmic nucleoporin NUP214 in a mutually exclusive manner. Nat Struct Mol Biol (2009) 1.68
The small subunit processome in ribosome biogenesis—progress and prospects. Wiley Interdiscip Rev RNA (2011) 1.66
The T4 phage SF1B helicase Dda is structurally optimized to perform DNA strand separation. Structure (2012) 1.52
Hepatitis C viral NS3-4A protease activity is enhanced by the NS3 helicase. J Biol Chem (2008) 1.50
Structure of the Yeast DEAD box protein Mss116p reveals two wedges that crimp RNA. Mol Cell (2009) 1.44
Structural evidence for consecutive Hel308-like modules in the spliceosomal ATPase Brr2. Nat Struct Mol Biol (2009) 1.40
The DEXD/H-box RNA helicase DDX19 is regulated by an {alpha}-helical switch. J Biol Chem (2009) 1.39
Degradation of hypomodified tRNA(iMet) in vivo involves RNA-dependent ATPase activity of the DExH helicase Mtr4p. RNA (2007) 1.39
DEAD-box proteins as RNA helicases and chaperones. Wiley Interdiscip Rev RNA (2011) 1.37
Prp43p contains a processive helicase structural architecture with a specific regulatory domain. EMBO J (2010) 1.36
Single-molecule analysis reveals differential effect of ssDNA-binding proteins on DNA translocation by XPD helicase. Mol Cell (2009) 1.32
Unwinding by local strand separation is critical for the function of DEAD-box proteins as RNA chaperones. J Mol Biol (2009) 1.30
Function of the C-terminal domain of the DEAD-box protein Mss116p analyzed in vivo and in vitro. J Mol Biol (2007) 1.29
mRNA secondary structures fold sequentially but exchange rapidly in vivo. PLoS Biol (2010) 1.28
Interactions between eIF4AI and its accessory factors eIF4B and eIF4H. RNA (2008) 1.23
Induction of type I interferon by RNA viruses: cellular receptors and their substrates. Amino Acids (2009) 1.22
Correlation of microRNA levels during hypoxia with predicted target mRNAs through genome-wide microarray analysis. BMC Med Genomics (2009) 1.13
The spliceosomal proteome: at the heart of the largest cellular ribonucleoprotein machine. Proteomics (2010) 1.13
The ATPase and helicase activities of Prp43p are stimulated by the G-patch protein Pfa1p during yeast ribosome biogenesis. EMBO J (2009) 1.12
A conserved phenylalanine of motif IV in superfamily 2 helicases is required for cooperative, ATP-dependent binding of RNA substrates in DEAD-box proteins. Mol Cell Biol (2008) 1.10
Unwinding RNA's secrets: advances in the biology, physics, and modeling of complex RNAs. Curr Opin Struct Biol (2008) 1.10
Duplex RNA activated ATPases (DRAs): platforms for RNA sensing, signaling and processing. RNA Biol (2012) 1.10
Unique and important consequences of RECQ1 deficiency in mammalian cells. Cell Cycle (2008) 1.09
Characterization of the SOS regulon of Caulobacter crescentus. J Bacteriol (2007) 1.09
Dbp5, Gle1-IP6 and Nup159: a working model for mRNP export. Nucleus (2011) 1.08
Solution structures of DEAD-box RNA chaperones reveal conformational changes and nucleic acid tethering by a basic tail. Proc Natl Acad Sci U S A (2011) 1.06
The 5' guanosine tracts of human telomerase RNA are recognized by the G-quadruplex binding domain of the RNA helicase DHX36 and function to increase RNA accumulation. Mol Cell Biol (2010) 1.04
Tight intramolecular regulation of the human Upf1 helicase by its N- and C-terminal domains. Nucleic Acids Res (2012) 1.04
Genes that Affect Brain Structure and Function Identified by Rare Variant Analyses of Mendelian Neurologic Disease. Neuron (2015) 1.03
RNA helicases: diverse roles in prokaryotic response to abiotic stress. RNA Biol (2012) 1.01
Roles of DEAD-box proteins in RNA and RNP Folding. RNA Biol (2010) 0.99
Parts, assembly and operation of the RIG-I family of motors. Curr Opin Struct Biol (2013) 0.97
SrmB, a DEAD-box helicase involved in Escherichia coli ribosome assembly, is specifically targeted to 23S rRNA in vivo. Nucleic Acids Res (2009) 0.94
Intermolecular interactions within the abundant DEAD-box protein Dhh1 regulate its activity in vivo. J Biol Chem (2011) 0.94
Organelle-nucleus cross-talk regulates plant intercellular communication via plasmodesmata. Proc Natl Acad Sci U S A (2011) 0.94
DEXH-Box protein DHX30 is required for optimal function of the zinc-finger antiviral protein. Protein Cell (2010) 0.94
Single-molecule studies reveal that DEAD box protein DDX1 promotes oligomerization of HIV-1 Rev on the Rev response element. J Mol Biol (2011) 0.93
The function of RH22, a DEAD RNA helicase, in the biogenesis of the 50S ribosomal subunits of Arabidopsis chloroplasts. Plant Physiol (2011) 0.93
Cofactor-dependent specificity of a DEAD-box protein. Proc Natl Acad Sci U S A (2013) 0.92
Establishing the role of ATP for the function of the RIG-I innate immune sensor. Elife (2015) 0.92
ATP-dependent roles of the DEAD-box protein Mss116p in group II intron splicing in vitro and in vivo. J Mol Biol (2011) 0.90
Superfamily 2 helicases. Front Biosci (Landmark Ed) (2012) 0.89
Structure and Mechanisms of SF1 DNA Helicases. Adv Exp Med Biol (2013) 0.86
Phylogenetic distribution and evolutionary history of bacterial DEAD-Box proteins. J Mol Evol (2011) 0.86
DEAD-box protein CYT-19 is activated by exposed helices in a group I intron RNA. Proc Natl Acad Sci U S A (2014) 0.85
Crystal structure of the human eIF4AIII-CWC22 complex shows how a DEAD-box protein is inhibited by a MIF4G domain. Proc Natl Acad Sci U S A (2013) 0.85
NSs encoded by groundnut bud necrosis virus is a bifunctional enzyme. PLoS One (2010) 0.84
RNA reactions one molecule at a time. Cold Spring Harb Perspect Biol (2010) 0.83
DEAD-box proteins from Escherichia coli exhibit multiple ATP-independent activities. J Bacteriol (2011) 0.82
The putative RNA helicase HELZ promotes cell proliferation, translation initiation and ribosomal protein S6 phosphorylation. PLoS One (2011) 0.82
Helicase-mediated changes in RNA structure at the single-molecule level. RNA Biol (2013) 0.82
Protein fragments: functional and structural roles of their coevolution networks. PLoS One (2012) 0.82
Insights into mRNA export-linked molecular mechanisms of human disease through a Gle1 structure-function analysis. Adv Biol Regul (2013) 0.82
In silico investigation of conformational motions in superfamily 2 helicase proteins. PLoS One (2011) 0.81
The Many Roles of BAF (mSWI/SNF) and PBAF Complexes in Cancer. Cold Spring Harb Perspect Med (2016) 0.81
Structural and functional analysis of the human spliceosomal DEAD-box helicase Prp28. Acta Crystallogr D Biol Crystallogr (2014) 0.80
Mss116p: a DEAD-box protein facilitates RNA folding. RNA Biol (2012) 0.80
Dual nature of translational control by regulatory BC RNAs. Mol Cell Biol (2011) 0.80
Molecular dynamics simulation of the allosteric regulation of eIF4A protein from the open to closed state, induced by ATP and RNA substrates. PLoS One (2014) 0.80
Crystallization and preliminary X-ray diffraction of the DEAD-box protein Mss116p complexed with an RNA oligonucleotide and AMP-PNP. Acta Crystallogr Sect F Struct Biol Cryst Commun (2009) 0.79
An Arabidopsis ATP-dependent, DEAD-box RNA helicase loses activity upon IsoAsp formation but is restored by PROTEIN ISOASPARTYL METHYLTRANSFERASE. Plant Cell (2013) 0.79
Steady-state NTPase activity of Dengue virus NS3: number of catalytic sites, nucleotide specificity and activation by ssRNA. PLoS One (2013) 0.78
Ddx1 knockout results in transgenerational wild-type lethality in mice. Sci Rep (2015) 0.77
Phylogenetic relationship of some "accessory" helicases of plant positive-stranded RNA viruses: toward understanding the evolution of triple gene block. Front Microbiol (2015) 0.77
Hepatitis C virus replication and potential targets for direct-acting agents. Therap Adv Gastroenterol (2010) 0.77
Rapid purification of helicase proteins and in vitro analysis of helicase activity. Methods (2010) 0.77
Putative SF2 helicases of the early-branching eukaryote Giardia lamblia are involved in antigenic variation and parasite differentiation into cysts. BMC Microbiol (2012) 0.76
Structural analyses of the pre-mRNA splicing machinery. Protein Sci (2013) 0.75
Acquisition of Full-Length Viral Helicase Domains by Insect Retrotransposon-Encoded Polypeptides. Front Microbiol (2015) 0.75
The DEAD-box Protein DDX43 (HAGE) Is a Dual RNA-DNA Helicase and Has a K-homology Domain Required for Full Nucleic Acid Unwinding Activity. J Biol Chem (2017) 0.75
Human Nup98 regulates the localization and activity of DExH/D-box helicase DHX9. Elife (2017) 0.75
Structural insights into the mechanism of the DEAH-box RNA helicase Prp43. Elife (2017) 0.75
Functional link between DEAH/RHA helicase Prp43 activation and ATP base binding. Nucleic Acids Res (2017) 0.75
Computational biology approach to uncover hepatitis C virus helicase operation. World J Gastroenterol (2014) 0.75
Structure of the SPRY domain of the human RNA helicase DDX1, a putative interaction platform within a DEAD-box protein. Acta Crystallogr F Struct Biol Commun (2015) 0.75
Monomeric nature of dengue virus NS3 helicase and thermodynamic analysis of the interaction with single-stranded RNA. Nucleic Acids Res (2014) 0.75
Crystal structure of Middle East respiratory syndrome coronavirus helicase. PLoS Pathog (2017) 0.75
The LOTUS domain is a conserved DEAD-box RNA helicase regulator essential for the recruitment of Vasa to the germ plasm and nuage. Genes Dev (2017) 0.75
Discriminatory RNP remodeling by the DEAD-box protein DED1. RNA (2006) 1.09
DEAD-box-protein-assisted RNA structure conversion towards and against thermodynamic equilibrium values. J Mol Biol (2007) 0.96
RNA unwinding activity of the hepatitis C virus NS3 helicase is modulated by the NS5B polymerase. Biochemistry (2008) 0.96
RNA helicases: versatile ATP-driven nanomotors. J Nanosci Nanotechnol (2005) 0.86
Duplex unwinding and RNP remodeling with RNA helicases. Methods Mol Biol (2008) 0.85