Published in J Biol Chem on July 16, 2007
Role of androgens and the androgen receptor in epithelial-mesenchymal transition and invasion of prostate cancer cells. FASEB J (2009) 1.67
Activation of androgen receptor, lipogenesis, and oxidative stress converged by SREBP-1 is responsible for regulating growth and progression of prostate cancer cells. Mol Cancer Res (2011) 1.37
Targeting the androgen receptor pathway in castration-resistant prostate cancer: progresses and prospects. Oncogene (2014) 1.31
Paxillin regulates androgen- and epidermal growth factor-induced MAPK signaling and cell proliferation in prostate cancer cells. J Biol Chem (2010) 1.24
Phosphoinositide 3-kinase signaling in the vertebrate retina. J Lipid Res (2010) 1.15
Phosphoinositide 3-OH kinase p85alpha and p110beta are essential for androgen receptor transactivation and tumor progression in prostate cancers. Oncogene (2008) 1.13
Novel protein ADTRP regulates TFPI expression and function in human endothelial cells in normal conditions and in response to androgen. Blood (2011) 1.12
Dysregulation of cholesterol homeostasis in human prostate cancer through loss of ABCA1. Cancer Res (2012) 1.10
Androgen receptor survival signaling is blocked by anti-beta2-microglobulin monoclonal antibody via a MAPK/lipogenic pathway in human prostate cancer cells. J Biol Chem (2010) 1.04
Rapid preparation of nuclei-depleted detergent-resistant membrane fractions suitable for proteomics analysis. BMC Cell Biol (2008) 1.03
Statins and prostate cancer: role of cholesterol inhibition vs. prevention of small GTP-binding proteins. Am J Cancer Res (2011) 0.97
MST1 is a multifunctional caspase-independent inhibitor of androgenic signaling. Cancer Res (2011) 0.95
Plasma membrane cholesterol content affects nitric oxide diffusion dynamics and signaling. J Biol Chem (2008) 0.93
A RASSF1A polymorphism restricts p53/p73 activation and associates with poor survival and accelerated age of onset of soft tissue sarcoma. Cancer Res (2012) 0.93
The impact of point mutations in the human androgen receptor: classification of mutations on the basis of transcriptional activity. PLoS One (2012) 0.92
Modulators of prostate cancer cell proliferation and viability identified by short-hairpin RNA library screening. PLoS One (2012) 0.90
Prenylated c17orf37 induces filopodia formation to promote cell migration and metastasis. J Biol Chem (2011) 0.90
Metabolomic analysis of prostate cancer risk in a prospective cohort: The alpha-tocolpherol, beta-carotene cancer prevention (ATBC) study. Int J Cancer (2015) 0.90
Androgen receptor drives cellular senescence. PLoS One (2012) 0.89
Involvement of androgens in ovarian health and disease. Mol Hum Reprod (2013) 0.86
Scaffold attachment factor B1 regulates the androgen receptor in concert with the growth inhibitory kinase MST1 and the methyltransferase EZH2. Oncogene (2013) 0.85
Integrins regulate microtubule nucleating activity of centrosome through mitogen-activated protein kinase/extracellular signal-regulated kinase kinase/extracellular signal-regulated kinase (MEK/ERK) signaling. J Biol Chem (2011) 0.85
Cholesterol and benign prostate disease. Differentiation (2011) 0.85
Sex-based differences in skeletal muscle kinetics and fiber-type composition. Physiology (Bethesda) (2015) 0.81
Direct interaction between AR and PAK6 in androgen-stimulated PAK6 activation. PLoS One (2013) 0.79
Androgen receptor-mediated non-genomic regulation of prostate cancer cell proliferation. Transl Androl Urol (2013) 0.78
Steroid signaling activation and intracellular localization of sex steroid receptors. J Cell Commun Signal (2010) 0.77
5alpha-androstane-3alpha,17beta-diol selectively activates the canonical PI3K/AKT pathway: a bioinformatics-based evidence for androgen-activated cytoplasmic signaling. Genomic Med (2008) 0.76
Androgens and esophageal cancer: What do we know? World J Gastroenterol (2015) 0.75
Male hormones activate EphA2 to facilitate Kaposi's sarcoma-associated herpesvirus infection: Implications for gender disparity in Kaposi's sarcoma. PLoS Pathog (2017) 0.75
Membrane steroid receptor-mediated action of soy isoflavones: tip of the iceberg. J Membr Biol (2014) 0.75
Mapping the STK4/Hippo signaling network in prostate cancer cell. PLoS One (2017) 0.75
Cholesterol targeting alters lipid raft composition and cell survival in prostate cancer cells and xenografts. J Clin Invest (2005) 2.89
Single photon-emission computed tomography. J Nucl Cardiol (2010) 2.57
Proteome scale characterization of human S-acylated proteins in lipid raft-enriched and non-raft membranes. Mol Cell Proteomics (2009) 2.16
Cholesterol-rich lipid rafts mediate akt-regulated survival in prostate cancer cells. Cancer Res (2002) 2.11
Oncosome formation in prostate cancer: association with a region of frequent chromosomal deletion in metastatic disease. Cancer Res (2009) 2.07
Ontario multidetector computed tomographic coronary angiography study: field evaluation of diagnostic accuracy. Arch Intern Med (2011) 1.97
Impact of circulating cholesterol levels on growth and intratumoral androgen concentration of prostate tumors. PLoS One (2012) 1.89
An absence of stromal caveolin-1 is associated with advanced prostate cancer, metastatic disease and epithelial Akt activation. Cell Cycle (2009) 1.88
Do the cholesterol-lowering properties of statins affect cancer risk? Trends Endocrinol Metab (2008) 1.74
The pro-apoptotic kinase Mst1 and its caspase cleavage products are direct inhibitors of Akt1. EMBO J (2007) 1.69
Signaling through PI3K/Akt mediates stretch and PDGF-BB-dependent DNA synthesis in bladder smooth muscle cells. J Urol (2003) 1.65
Large oncosomes in human prostate cancer tissues and in the circulation of mice with metastatic disease. Am J Pathol (2012) 1.60
The ubiquitin-specific protease USP2a enhances tumor progression by targeting cyclin A1 in bladder cancer. Cell Cycle (2012) 1.56
Marked disturbance of calcium homeostasis in mice with targeted disruption of the Trpv6 calcium channel gene. J Bone Miner Res (2007) 1.56
Cholesterol sensitivity of endogenous and myristoylated Akt. Cancer Res (2007) 1.45
The role of cholesterol in prostate cancer. Curr Opin Clin Nutr Metab Care (2006) 1.43
Pharmacologic management of painful bladder syndrome/interstitial cystitis: a systematic review. Arch Intern Med (2007) 1.38
Human papillomavirus oncoprotein E6 inactivates the transcriptional coactivator human ADA3. Mol Cell Biol (2002) 1.38
Human papilloma virus 16 E6 oncoprotein inhibits retinoic X receptor-mediated transactivation by targeting human ADA3 coactivator. J Biol Chem (2002) 1.32
Post-transcriptional regulation of the androgen receptor by Mammalian target of rapamycin. Cancer Res (2005) 1.31
Calcium-selective ion channel, CaT1, is apically localized in gastrointestinal tract epithelia and is aberrantly expressed in human malignancies. Lab Invest (2002) 1.30
Cholesterol and prostate cancer. Curr Opin Pharmacol (2012) 1.28
Caveolin-1 interacts with a lipid raft-associated population of fatty acid synthase. Cell Cycle (2008) 1.20
The zinc finger protein ras-responsive element binding protein-1 is a coregulator of the androgen receptor: implications for the role of the Ras pathway in enhancing androgenic signaling in prostate cancer. Mol Endocrinol (2007) 1.20
Calcium regulates the PI3K-Akt pathway in stretched osteoblasts. FEBS Lett (2003) 1.19
Optimizing sample handling for urinary proteomics. J Proteome Res (2008) 1.18
Ezetimibe is an inhibitor of tumor angiogenesis. Am J Pathol (2009) 1.18
Mechanical stretch is a highly selective regulator of gene expression in human bladder smooth muscle cells. Physiol Genomics (2004) 1.17
A quantitative proteomic analysis of growth factor-induced compositional changes in lipid rafts of human smooth muscle cells. Proteomics (2005) 1.15
Proteomic analysis of palmitoylated platelet proteins. Blood (2011) 1.14
p53 mediates interstitial cystitis antiproliferative factor (APF)-induced growth inhibition of human urothelial cells. FEBS Lett (2007) 1.14
Inhibitor of apoptosis protein-1 promotes tumor cell survival in mesothelioma. Carcinogenesis (2002) 1.14
The phosphoinositide kinase PIKfyve mediates epidermal growth factor receptor trafficking to the nucleus. Cancer Res (2007) 1.13
The complex interplay between cholesterol and prostate malignancy. Urol Clin North Am (2011) 1.13
Beta-amyloid deposition in chronic traumatic encephalopathy. Acta Neuropathol (2015) 1.12
Large oncosomes mediate intercellular transfer of functional microRNA. Cell Cycle (2013) 1.12
An hTERT-immortalized human urothelial cell line that responds to anti-proliferative factor. In Vitro Cell Dev Biol Anim (2010) 1.10
Measurement of plasma levels of vascular endothelial growth factor in prostate cancer patients: relationship with clinical stage, Gleason score, prostate volume, and serum prostate-specific antigen. Clinics (Sao Paulo) (2006) 1.07
Caveolin-1alpha and -1beta perform nonredundant roles in early vertebrate development. Am J Pathol (2006) 1.06
Trafficking of nuclear heparin-binding epidermal growth factor-like growth factor into an epidermal growth factor receptor-dependent autocrine loop in response to oxidative stress. Cancer Res (2005) 1.04
Rapid preparation of nuclei-depleted detergent-resistant membrane fractions suitable for proteomics analysis. BMC Cell Biol (2008) 1.03
MicroRNA-185 and 342 inhibit tumorigenicity and induce apoptosis through blockade of the SREBP metabolic pathway in prostate cancer cells. PLoS One (2013) 1.03
Reversible regional wall motion abnormalities on exercise technetium-99m-gated cardiac single photon emission computed tomography predict high-grade angiographic stenoses. J Am Coll Cardiol (2002) 1.03
Heterogeneous nuclear ribonucleoprotein K is a novel regulator of androgen receptor translation. Cancer Res (2009) 1.02
Cholesterol and cholesterol-rich membranes in prostate cancer: an update. Tumori (2008) 1.02
Activation of the Erk mitogen-activated protein kinase pathway stimulates neuroendocrine differentiation in LNCaP cells independently of cell cycle withdrawal and STAT3 phosphorylation. Cancer Res (2002) 1.02
Proteomic approaches to the analysis of multiprotein signaling complexes. Proteomics (2008) 1.01
DIAPH3 governs the cellular transition to the amoeboid tumour phenotype. EMBO Mol Med (2012) 1.01
Transit of hormonal and EGF receptor-dependent signals through cholesterol-rich membranes. Steroids (2006) 1.00
Involvement of cholesterol-rich lipid rafts in interleukin-6-induced neuroendocrine differentiation of LNCaP prostate cancer cells. Endocrinology (2003) 1.00
A nuclear form of the heparin-binding epidermal growth factor-like growth factor precursor is a feature of aggressive transitional cell carcinoma. Cancer Res (2003) 1.00
Acrolein induces cyclooxygenase-2 and prostaglandin production in human umbilical vein endothelial cells: roles of p38 MAP kinase. Arterioscler Thromb Vasc Biol (2007) 0.99
VEGF receptors and neuropilins are expressed in the urothelial and neuronal cells in normal mouse urinary bladder and are upregulated in inflammation. Am J Physiol Renal Physiol (2008) 0.98
Heparin-binding epidermal growth factor-like growth factor stimulates androgen-independent prostate tumor growth and antagonizes androgen receptor function. Endocrinology (2002) 0.97
Platelet derived growth factor-BB is a potent mitogen for rat ureteral and human bladder smooth muscle cells: dependence on lipid rafts for cell signaling. J Urol (2003) 0.96
MST1 is a multifunctional caspase-independent inhibitor of androgenic signaling. Cancer Res (2011) 0.95
Quantitative proteomics identifies a beta-catenin network as an element of the signaling response to Frizzled-8 protein-related antiproliferative factor. Mol Cell Proteomics (2011) 0.94
Antiproliferative factor signaling and interstitial cystitis/painful bladder syndrome. Int Neurourol J (2011) 0.94
Skp2 expression is associated with high risk and elevated Ki67 expression in gastrointestinal stromal tumours. BMC Cancer (2008) 0.94
RANK- and c-Met-mediated signal network promotes prostate cancer metastatic colonization. Endocr Relat Cancer (2014) 0.93
Identification and characterization of proteins isolated from microvesicles derived from human lung cancer pleural effusions. Proteomics (2013) 0.93
Caveolin-1 is required for the upregulation of fatty acid synthase (FASN), a tumor promoter, during prostate cancer progression. Cancer Biol Ther (2007) 0.92
Suppression of aberrant transient receptor potential cation channel, subfamily V, member 6 expression in hyperproliferative colonic crypts by dietary calcium. Am J Physiol Gastrointest Liver Physiol (2010) 0.90
Unraveling androgen receptor interactomes by an array-based method: discovery of proto-oncoprotein c-Rel as a negative regulator of androgen receptor. Exp Cell Res (2006) 0.90
'Omics' approaches to understanding interstitial cystitis/painful bladder syndrome/bladder pain syndrome. Int Neurourol J (2012) 0.90
Management of chronic prostatitis/chronic pelvic pain syndrome: an evidence-based approach. Urology (2006) 0.89
Cholesterol-regulated stress fiber formation. J Cell Biochem (2009) 0.89
Cardiac imaging for risk stratification in diabetes. Diabetes Care (2007) 0.89
Statins and the risk of cancer. JAMA (2006) 0.88
A signaling network in phenylephrine-induced benign prostatic hyperplasia. Endocrinology (2009) 0.88
Urinary metabolite profiling combined with computational analysis predicts interstitial cystitis-associated candidate biomarkers. J Proteome Res (2014) 0.87
Temporal variations of the postnatal rat urinary proteome as a reflection of systemic maturation. Proteomics (2008) 0.87
VentX trans-activates p53 and p16ink4a to regulate cellular senescence. J Biol Chem (2011) 0.86
Quantitative proteomics analysis reveals molecular networks regulated by epidermal growth factor receptor level in head and neck cancer. J Proteome Res (2010) 0.85
The response of the prostate to circulating cholesterol: activating transcription factor 3 (ATF3) as a prominent node in a cholesterol-sensing network. PLoS One (2012) 0.84
Caveolae are negative regulators of transforming growth factor-beta1 signaling in ureteral smooth muscle cells. J Urol (2004) 0.84
Proteomics and opportunities for clinical translation in urological disease. J Urol (2009) 0.84
JNK/SAPK mediates doxorubicin-induced differentiation and apoptosis in MCF-7 breast cancer cells. Breast Cancer Res Treat (2003) 0.84
Transactivation of ErbB1 and ErbB2 receptors by angiotensin II in normal human prostate stromal cells. Prostate (2003) 0.84
Integration analysis of quantitative proteomics and transcriptomics data identifies potential targets of frizzled-8 protein-related antiproliferative factor in vivo. BJU Int (2012) 0.83
Cloning and functional characterization of the murine mastermind-like 1 (Maml1) gene. Gene (2004) 0.83
Extracellular vesicles shed from gefitinib-resistant nonsmall cell lung cancer regulate the tumor microenvironment. Proteomics (2014) 0.83
Hypercholesterolemia promotes an osteoporotic phenotype. Am J Pathol (2012) 0.82
An oxidative stress mechanism mediates chelerythrine-induced heparin-binding EGF-like growth factor ectodomain shedding. J Cell Biochem (2005) 0.82
Beta2 microglobulin: a surprising therapeutic target for prostate cancer and renal cell carcinoma. J Urol (2007) 0.81
Tumor cell-associated neuropilin-1 and vascular endothelial growth factor expression as determinants of tumor growth in neuroblastoma. Neuropathology (2005) 0.81
Drug delivery systems in urology--getting "smarter". Urology (2006) 0.81
Increasing the ranks of physician-scientists in urology through the promotion of fellowship training: the example of pediatric urology. J Urol (2005) 0.80
The decision to undergo DNA or protein synthesis is determined by the degree of mechanical deformation in human bladder muscle cells. Urology (2002) 0.80
Inhibition of EGFR signaling abrogates smooth muscle proliferation resulting from sustained distension of the urinary bladder. Lab Invest (2006) 0.79
Ezetimibe reduces enlarged prostate in an animal model of benign prostatic hyperplasia. J Urol (2010) 0.78
Growth and stretch response of human exstrophy bladder smooth muscle cells: molecular evidence of normal intrinsic function. BJU Int (2005) 0.77
A synthetic form of frizzled 8-associated antiproliferative factor enhances p53 stability through USP2a and MDM2. PLoS One (2012) 0.77
Behavioral profiling of human transitional cell carcinoma ex vivo. Cancer Res (2006) 0.76
Left ventricular function during arm exercise: influence of leg cycling and lower body positive pressure. J Appl Physiol (1985) (2006) 0.76