Published in J Neurosci on August 01, 2007
Assessing mitochondrial dysfunction in cells. Biochem J (2011) 6.36
Mitochondrial membrane potential probes and the proton gradient: a practical usage guide. Biotechniques (2011) 2.51
Brain lactate metabolism: the discoveries and the controversies. J Cereb Blood Flow Metab (2011) 1.71
Mitochondrial degradation by autophagy (mitophagy) in GFP-LC3 transgenic hepatocytes during nutrient deprivation. Am J Physiol Cell Physiol (2010) 1.32
AMP kinase-mediated activation of the BH3-only protein Bim couples energy depletion to stress-induced apoptosis. J Cell Biol (2010) 1.17
Roles of glucose in photoreceptor survival. J Biol Chem (2011) 1.09
Quantitative measurement of mitochondrial membrane potential in cultured cells: calcium-induced de- and hyperpolarization of neuronal mitochondria. J Physiol (2012) 1.07
Differential NMDA receptor-dependent calcium loading and mitochondrial dysfunction in CA1 vs. CA3 hippocampal neurons. Neurobiol Dis (2009) 0.98
AMP-activated protein kinase mediates apoptosis in response to bioenergetic stress through activation of the pro-apoptotic Bcl-2 homology domain-3-only protein BMF. J Biol Chem (2010) 0.94
Cytosolic calcium coordinates mitochondrial energy metabolism with presynaptic activity. J Neurosci (2012) 0.93
Mitochondrial depolarization and electrophysiological changes during ischemia in the rabbit and human heart. Am J Physiol Heart Circ Physiol (2014) 0.93
Mechanisms and methods in glucose metabolism and cell death. Methods Enzymol (2008) 0.92
Essential role of the redox-sensitive kinase p66shc in determining energetic and oxidative status and cell fate in neuronal preconditioning. J Neurosci (2010) 0.91
Two-step activation of FOXO3 by AMPK generates a coherent feed-forward loop determining excitotoxic cell fate. Cell Death Differ (2012) 0.89
Function of the master energy regulator adenosine monophosphate-activated protein kinase in stroke. J Neurosci Res (2013) 0.88
Deletion of Puma protects hippocampal neurons in a model of severe status epilepticus. Neuroscience (2010) 0.88
Quantifying mitochondrial and plasma membrane potentials in intact pulmonary arterial endothelial cells based on extracellular disposition of rhodamine dyes. Am J Physiol Lung Cell Mol Physiol (2011) 0.87
Plasma membrane Ca2+-ATPase isoforms composition regulates cellular pH homeostasis in differentiating PC12 cells in a manner dependent on cytosolic Ca2+ elevations. PLoS One (2014) 0.85
Measurement of technetium-99m sestamibi signals in rats administered a mitochondrial uncoupler and in a rat model of heart failure. PLoS One (2015) 0.85
Comparative analysis of cytosolic and mitochondrial ATP synthesis in embryonic and postnatal hippocampal neuronal cultures. Front Mol Neurosci (2013) 0.84
Oxidative stress defines the neuroprotective or neurotoxic properties of androgens in immortalized female rat dopaminergic neuronal cells. Endocrinology (2013) 0.83
GSTT1 is upregulated by oxidative stress through p38-MK2 signaling pathway in human granulosa cells: possible association with mitochondrial activity. Aging (Albany NY) (2011) 0.80
The metabolic response to excitotoxicity - lessons from single-cell imaging. J Bioenerg Biomembr (2014) 0.78
RCAN1 overexpression promotes age-dependent mitochondrial dysregulation related to neurodegeneration in Alzheimer's disease. Acta Neuropathol (2015) 0.78
Latrepirdine is a potent activator of AMP-activated protein kinase and reduces neuronal excitability. Transl Psychiatry (2013) 0.76
Oxidative stress response in neural stem cells exposed to different superparamagnetic iron oxide nanoparticles. Int J Nanomedicine (2016) 0.75
Exploring cells with targeted biosensors. J Gen Physiol (2016) 0.75
Being right on Q: shaping eukaryotic evolution. Biochem J (2016) 0.75
Computational Analysis of AMPK-Mediated Neuroprotection Suggests Acute Excitotoxic Bioenergetics and Glucose Dynamics Are Regulated by a Minimal Set of Critical Reactions. PLoS One (2016) 0.75
Mitochondrial potential (ΔΨm) changes in single rat hepatocytes: the effect of orthovanadate nanoparticles doped with rare-earth elements. Eur Phys J E Soft Matter (2014) 0.75
Assessing mitochondrial dysfunction in cells. Biochem J (2011) 6.36
Bioenergetic analysis of isolated cerebrocortical nerve terminals on a microgram scale: spare respiratory capacity and stochastic mitochondrial failure. J Neurochem (2009) 2.92
Quantitative microplate-based respirometry with correction for oxygen diffusion. Anal Chem (2009) 2.86
Gene expression during ER stress-induced apoptosis in neurons: induction of the BH3-only protein Bbc3/PUMA and activation of the mitochondrial apoptosis pathway. J Cell Biol (2003) 2.42
Spare respiratory capacity rather than oxidative stress regulates glutamate excitotoxicity after partial respiratory inhibition of mitochondrial complex I with rotenone. J Neurosci (2007) 2.23
Calpain I induces cleavage and release of apoptosis-inducing factor from isolated mitochondria. J Biol Chem (2004) 2.17
The relationship between free and total calcium concentrations in the matrix of liver and brain mitochondria. J Biol Chem (2003) 1.97
Single-cell fluorescence resonance energy transfer analysis demonstrates that caspase activation during apoptosis is a rapid process. Role of caspase-3. J Biol Chem (2002) 1.96
S100B in brain damage and neurodegeneration. Microsc Res Tech (2003) 1.85
Real-time single cell analysis of Smac/DIABLO release during apoptosis. J Cell Biol (2003) 1.81
Systems analysis of effector caspase activation and its control by X-linked inhibitor of apoptosis protein. EMBO J (2006) 1.79
Deletion of the BH3-only protein puma protects motoneurons from ER stress-induced apoptosis and delays motoneuron loss in ALS mice. Proc Natl Acad Sci U S A (2007) 1.58
In situ respiration and bioenergetic status of mitochondria in primary cerebellar granule neuronal cultures exposed continuously to glutamate. J Biol Chem (2004) 1.57
Control of motoneuron survival by angiogenin. J Neurosci (2008) 1.53
Inducible alterations of glutathione levels in adult dopaminergic midbrain neurons result in nigrostriatal degeneration. J Neurosci (2007) 1.41
MAO-B elevation in mouse brain astrocytes results in Parkinson's pathology. PLoS One (2008) 1.39
Mitochondrial dysfunction in Huntington's disease: the bioenergetics of isolated and in situ mitochondria from transgenic mice. J Neurochem (2007) 1.32
Apoptosis signaling proteins as prognostic biomarkers in colorectal cancer: a review. Biochim Biophys Acta (2009) 1.31
Acute glutathione depletion restricts mitochondrial ATP export in cerebellar granule neurons. J Biol Chem (2005) 1.30
Tight coupling between glucose and mitochondrial metabolism in clonal beta-cells is required for robust insulin secretion. J Biol Chem (2009) 1.30
Measurement of instantaneous velocity vectors of organelle transport: mitochondrial transport and bioenergetics in hippocampal neurons. Biophys J (2008) 1.26
Experimental assessment of bioenergetic differences caused by the common European mitochondrial DNA haplogroups H and T. Gene (2008) 1.26
Modulation of gene expression and cytoskeletal dynamics by the amyloid precursor protein intracellular domain (AICD). Mol Biol Cell (2006) 1.26
Effects of neuroglobin overexpression on mitochondrial function and oxidative stress following hypoxia/reoxygenation in cultured neurons. J Neurosci Res (2009) 1.25
Regulation of glucose transporter 3 surface expression by the AMP-activated protein kinase mediates tolerance to glutamate excitation in neurons. J Neurosci (2009) 1.24
Oxidative alpha-ketoglutarate dehydrogenase inhibition via subtle elevations in monoamine oxidase B levels results in loss of spare respiratory capacity: implications for Parkinson's disease. J Biol Chem (2003) 1.22
Vascular endothelial growth factor protects cultured rat hippocampal neurons against hypoxic injury via an antiexcitotoxic, caspase-independent mechanism. J Cereb Blood Flow Metab (2002) 1.20
Mitochondrial-dependent Ca2+ handling in Huntington's disease striatal cells: effect of histone deacetylase inhibitors. J Neurosci (2006) 1.19
TGF-{beta}1 activates two distinct type I receptors in neurons: implications for neuronal NF-{kappa}B signaling. J Cell Biol (2005) 1.19
AMP kinase-mediated activation of the BH3-only protein Bim couples energy depletion to stress-induced apoptosis. J Cell Biol (2010) 1.17
Reactive oxygen species regulation by AIF- and complex I-depleted brain mitochondria. Free Radic Biol Med (2009) 1.17
UCPs--unlikely calcium porters. Nat Cell Biol (2008) 1.17
Hippocampal transcriptome after status epilepticus in mice rendered seizure damage-tolerant by epileptic preconditioning features suppressed calcium and neuronal excitability pathways. Neurobiol Dis (2008) 1.16
Outer mitochondrial membrane permeabilization during apoptosis triggers caspase-independent mitochondrial and caspase-dependent plasma membrane potential depolarization: a single-cell analysis. J Cell Sci (2003) 1.13
Coincident enrichment of phosphorylated IkappaBalpha, activated IKK, and phosphorylated p65 in the axon initial segment of neurons. Mol Cell Neurosci (2006) 1.11
In vivo contributions of BH3-only proteins to neuronal death following seizures, ischemia, and traumatic brain injury. J Cereb Blood Flow Metab (2011) 1.11
Role of 5'-adenosine monophosphate-activated protein kinase in cell survival and death responses in neurons. Antioxid Redox Signal (2011) 1.10
Real time single cell analysis of Bid cleavage and Bid translocation during caspase-dependent and neuronal caspase-independent apoptosis. J Biol Chem (2005) 1.08
Paraoxonase promoter and intronic variants modify risk of sporadic amyotrophic lateral sclerosis. J Neurol Neurosurg Psychiatry (2007) 1.07
Quantitative measurement of mitochondrial membrane potential in cultured cells: calcium-induced de- and hyperpolarization of neuronal mitochondria. J Physiol (2012) 1.07
6-Hydroxydopamine activates the mitochondrial apoptosis pathway through p38 MAPK-mediated, p53-independent activation of Bax and PUMA. J Neurochem (2007) 1.07
The amyloid precursor protein intracellular domain(AICD) disrupts actin dynamics and mitochondrial bioenergetics. J Neurochem (2010) 1.06
Real time analysis of tumor necrosis factor-related apoptosis-inducing ligand/cycloheximide-induced caspase activities during apoptosis initiation. J Biol Chem (2008) 1.05
Dominant-negative suppression of HNF-1 alpha results in mitochondrial dysfunction, INS-1 cell apoptosis, and increased sensitivity to ceramide-, but not to high glucose-induced cell death. J Biol Chem (2001) 1.05
p75 neurotrophin receptor is required for constitutive and NGF-induced survival signalling in PC12 cells and rat hippocampal neurones. J Neurochem (2002) 1.04
Pharmacological inhibition of Bcl-2 family members reactivates TRAIL-induced apoptosis in malignant glioma. J Neurooncol (2007) 1.04
Mitochondrial DNA damage is associated with reduced mitochondrial bioenergetics in Huntington's disease. Free Radic Biol Med (2012) 1.04
Reduced hippocampal damage and epileptic seizures after status epilepticus in mice lacking proapoptotic Puma. FASEB J (2009) 1.03
CHOP regulates the p53-MDM2 axis and is required for neuronal survival after seizures. Brain (2013) 1.02
Upregulation of DR5 by proteasome inhibitors potently sensitizes glioma cells to TRAIL-induced apoptosis. FEBS J (2008) 1.01
Mitochondrial membrane permeabilization and superoxide production during apoptosis. A single-cell analysis. J Biol Chem (2003) 1.01
Full length Bid is sufficient to induce apoptosis of cultured rat hippocampal neurons. BMC Cell Biol (2007) 1.00
Real-time visualization of cytoplasmic calpain activation and calcium deregulation in acute glutamate excitotoxicity. J Neurochem (2009) 1.00
Endoplasmic reticulum stress and apoptosis signaling in human temporal lobe epilepsy. J Neuropathol Exp Neurol (2006) 0.99
Predicting pK(a) values of substituted phenols from atomic charges: comparison of different quantum mechanical methods and charge distribution schemes. J Chem Inf Model (2011) 0.99
Relationships between superoxide levels and delayed calcium deregulation in cultured cerebellar granule cells exposed continuously to glutamate. J Neurochem (2004) 0.99
The Myosin IXb motor activity targets the myosin IXb RhoGAP domain as cargo to sites of actin polymerization. Mol Biol Cell (2007) 0.98
INS-1 cells undergoing caspase-dependent apoptosis enhance the regenerative capacity of neighboring cells. Diabetes (2010) 0.97
NMDA receptor-mediated excitotoxic neuronal apoptosis in vitro and in vivo occurs in an ER stress and PUMA independent manner. J Neurochem (2007) 0.97
Calpains are downstream effectors of bax-dependent excitotoxic apoptosis. J Neurosci (2012) 0.97
Novel benzylidene-9(10H)-anthracenones as highly active antimicrotubule agents. Synthesis, antiproliferative activity, and inhibition of tubulin polymerization. J Med Chem (2003) 0.97
Motoneurons secrete angiogenin to induce RNA cleavage in astroglia. J Neurosci (2012) 0.97
Systems analysis of BCL2 protein family interactions establishes a model to predict responses to chemotherapy. Cancer Res (2013) 0.97
Expanding the substantial interactome of NEMO using protein microarrays. PLoS One (2010) 0.97
Proteasome inhibition can impair caspase-8 activation upon submaximal stimulation of apoptotic tumor necrosis factor-related apoptosis inducing ligand (TRAIL) signaling. J Biol Chem (2012) 0.96
The amyloid precursor protein protects PC12 cells against endoplasmic reticulum stress-induced apoptosis. J Neurochem (2003) 0.95
Xanthohumol-induced transient superoxide anion radical formation triggers cancer cells into apoptosis via a mitochondria-mediated mechanism. FASEB J (2010) 0.94
Intrinsic bioenergetic properties and stress sensitivity of dopaminergic synaptosomes. J Neurosci (2011) 0.94
Glucose-starved cells do not engage in prosurvival autophagy. J Biol Chem (2013) 0.94
Intracellular signaling dynamics during apoptosis execution in the presence or absence of X-linked-inhibitor-of-apoptosis-protein. Biochim Biophys Acta (2008) 0.94
AMP-activated protein kinase mediates apoptosis in response to bioenergetic stress through activation of the pro-apoptotic Bcl-2 homology domain-3-only protein BMF. J Biol Chem (2010) 0.94
Cytoplasmic inclusions of Htt exon1 containing an expanded polyglutamine tract suppress execution of apoptosis in sympathetic neurons. J Neurosci (2008) 0.93
Identification of polyubiquitin binding proteins involved in NF-kappaB signaling using protein arrays. Biochim Biophys Acta (2009) 0.92
Dynamics of intracellular oxygen in PC12 Cells upon stimulation of neurotransmission. J Biol Chem (2007) 0.91
Plasma membrane potential oscillations in insulin secreting Ins-1 832/13 cells do not require glycolysis and are not initiated by fluctuations in mitochondrial bioenergetics. J Biol Chem (2012) 0.91
BH3-only protein Bid is dispensable for seizure-induced neuronal death and the associated nuclear accumulation of apoptosis-inducing factor. J Neurochem (2010) 0.90
Glucose metabolism determines resistance of cancer cells to bioenergetic crisis after cytochrome-c release. Mol Syst Biol (2011) 0.90
Neuronal apoptosis: BH3-only proteins the real killers? J Bioenerg Biomembr (2004) 0.90
Depletion of 14-3-3 zeta elicits endoplasmic reticulum stress and cell death, and increases vulnerability to kainate-induced injury in mouse hippocampal cultures. J Neurochem (2008) 0.90
BH3 mimetics reactivate autophagic cell death in anoxia-resistant malignant glioma cells. Neoplasia (2008) 0.89
Production of reactive oxygen species and loss of viability in yeast mitochondrial mutants: protective effect of Bcl-xL. FEMS Yeast Res (2004) 0.88
Caspase-3 cleavage and nuclear localization of caspase-activated DNase in human temporal lobe epilepsy. J Cereb Blood Flow Metab (2006) 0.88
The amyloid precursor protein potentiates CHOP induction and cell death in response to ER Ca2+ depletion. Biochim Biophys Acta (2006) 0.87
Diffusion is capable of translating anisotropic apoptosis initiation into a homogeneous execution of cell death. BMC Syst Biol (2010) 0.87
In vivo bioluminescence imaging validation of a human biopsy-derived orthotopic mouse model of glioblastoma multiforme. Mol Imaging (2013) 0.87
Characterization of Puma-dependent and Puma-independent neuronal cell death pathways following prolonged proteasomal inhibition. Mol Cell Biol (2010) 0.86
Bid participates in genotoxic drug-induced apoptosis of HeLa cells and is essential for death receptor ligands' apoptotic and synergistic effects. PLoS One (2008) 0.86