Published in Am J Physiol Renal Physiol on August 15, 2007
Inducible podocyte injury and proteinuria in transgenic zebrafish. J Am Soc Nephrol (2012) 2.10
Genome-wide association and functional follow-up reveals new loci for kidney function. PLoS Genet (2012) 1.68
Pharmacological targeting of actin-dependent dynamin oligomerization ameliorates chronic kidney disease in diverse animal models. Nat Med (2015) 1.62
Genetic association for renal traits among participants of African ancestry reveals new loci for renal function. PLoS Genet (2011) 1.60
In vivo Modeling Implicates APOL1 in Nephropathy: Evidence for Dominant Negative Effects and Epistasis under Anemic Stress. PLoS Genet (2015) 1.52
Zebrafish: an emerging technology for in vivo pharmacological assessment to identify potential safety liabilities in early drug discovery. Br J Pharmacol (2008) 1.28
The role of the podocyte in albumin filtration. Nat Rev Nephrol (2013) 1.26
Cofilin-1 inactivation leads to proteinuria--studies in zebrafish, mice and humans. PLoS One (2010) 1.20
Mutations in the gene that encodes the F-actin binding protein anillin cause FSGS. J Am Soc Nephrol (2014) 1.12
SCRIB and PUF60 are primary drivers of the multisystemic phenotypes of the 8q24.3 copy-number variant. Am J Hum Genet (2013) 1.09
Generation and validation of a zebrafish model of EAST (epilepsy, ataxia, sensorineural deafness and tubulopathy) syndrome. Dis Model Mech (2013) 1.05
"Zebrafishing" for novel genes relevant to the glomerular filtration barrier. Biomed Res Int (2013) 0.98
A zebrafish model of conditional targeted podocyte ablation and regeneration. Kidney Int (2013) 0.95
Techniques for the in vivo assessment of cardio-renal function in zebrafish (Danio rerio) larvae. J Physiol (2012) 0.94
Using zebrafish to study podocyte genesis during kidney development and regeneration. Genesis (2014) 0.87
Zebrafish Renal Pathology: Emerging Models of Acute Kidney Injury. Curr Pathobiol Rep (2015) 0.87
A novel missense mutation of Wilms' Tumor 1 causes autosomal dominant FSGS. J Am Soc Nephrol (2014) 0.86
Nephrin and Podocin functions are highly conserved between the zebrafish pronephros and mammalian metanephros. Mol Med Rep (2013) 0.84
Podocyte developmental defects caused by adriamycin in zebrafish embryos and larvae: a novel model of glomerular damage. PLoS One (2014) 0.83
Shroom3 contributes to the maintenance of the glomerular filtration barrier integrity. Genome Res (2014) 0.83
Slit diaphragm protein Neph1 and its signaling: a novel therapeutic target for protection of podocytes against glomerular injury. J Biol Chem (2014) 0.83
Structural disorganization of pronephric glomerulus in zebrafish mpp5a/nagie oko mutant. Dev Dyn (2012) 0.82
Simultaneous assessment of glomerular filtration and barrier function in live zebrafish. Am J Physiol Renal Physiol (2014) 0.80
Recent advances in elucidating the genetic mechanisms of nephrogenesis using zebrafish. Cells (2015) 0.80
BDNF repairs podocyte damage by microRNA-mediated increase of actin polymerization. J Pathol (2015) 0.80
Insights into kidney stem cell development and regeneration using zebrafish. World J Stem Cells (2016) 0.79
Tankyrase inhibition aggravates kidney injury in the absence of CD2AP. Cell Death Dis (2016) 0.79
A Fluorescence-Based Assay for Proteinuria Screening in Larval Zebrafish (Danio rerio). Zebrafish (2015) 0.77
Delayed treatment with PTBA analogs reduces post injury renal fibrosis after kidney injury. Am J Physiol Renal Physiol (2015) 0.77
Assessing cardio-renal function in zebrafish larvae. J Physiol (2012) 0.75
The basal function of teleost prolactin as a key regulator on ion uptake identified with zebrafish knockout models. Sci Rep (2016) 0.75
ELMO1 protects renal structure and ultrafiltration in kidney development and under diabetic conditions. Sci Rep (2016) 0.75
Loss of Kynurenine 3-Mono-oxygenase Causes Proteinuria. J Am Soc Nephrol (2016) 0.75
SOS2 and ACP1 Loci Identified through Large-Scale Exome Chip Analysis Regulate Kidney Development and Function. J Am Soc Nephrol (2016) 0.75
Protein Kinase C ε Stabilizes β-Catenin and Regulates Its Subcellular Localization in Podocytes. J Biol Chem (2017) 0.75
Pituitary adenylate cyclase-activating polypeptide (PACAP) in zebrafish models of nephrotic syndrome. PLoS One (2017) 0.75
Zebrafish Models of Kidney Damage and Repair. Curr Pathobiol Rep (2015) 0.75
The zebrafish kidney mutant zeppelin reveals that brca2/fancd1 is essential for pronephros development. Dev Biol (2017) 0.75
Acute kidney injury, mortality, length of stay, and costs in hospitalized patients. J Am Soc Nephrol (2005) 18.76
Kidney Injury Molecule-1 (KIM-1): a novel biomarker for human renal proximal tubule injury. Kidney Int (2002) 8.03
Fate tracing reveals the pericyte and not epithelial origin of myofibroblasts in kidney fibrosis. Am J Pathol (2009) 7.34
Catheter-based renal nerve ablation and centrally generated sympathetic activity in difficult-to-control hypertensive patients: prospective case series. Hypertension (2012) 6.70
Intrinsic epithelial cells repair the kidney after injury. Cell Stem Cell (2008) 6.54
Glucose-induced reactive oxygen species cause apoptosis of podocytes and podocyte depletion at the onset of diabetic nephropathy. Diabetes (2006) 5.29
Reappraisal of European guidelines on hypertension management: a European Society of Hypertension Task Force document. J Hypertens (2009) 4.87
Epithelial cell cycle arrest in G2/M mediates kidney fibrosis after injury. Nat Med (2010) 4.76
The renal arterial resistance index and renal allograft survival. N Engl J Med (2003) 4.36
Restoration of tubular epithelial cells during repair of the postischemic kidney occurs independently of bone marrow-derived stem cells. J Clin Invest (2005) 4.10
Urinary kidney injury molecule-1: a sensitive quantitative biomarker for early detection of kidney tubular injury. Am J Physiol Renal Physiol (2005) 3.94
New-onset diabetes after transplantation: 2003 International consensus guidelines. Proceedings of an international expert panel meeting. Barcelona, Spain, 19 February 2003. Transplantation (2003) 3.79
Normalization of urinary biomarkers to creatinine during changes in glomerular filtration rate. Kidney Int (2010) 3.78
Kidney injury molecule-1: a tissue and urinary biomarker for nephrotoxicant-induced renal injury. Am J Physiol Renal Physiol (2003) 3.61
Kidney injury molecule-1 is a phosphatidylserine receptor that confers a phagocytic phenotype on epithelial cells. J Clin Invest (2008) 3.59
Urinary N-acetyl-beta-(D)-glucosaminidase activity and kidney injury molecule-1 level are associated with adverse outcomes in acute renal failure. J Am Soc Nephrol (2007) 3.48
Biomarkers of acute kidney injury. Annu Rev Pharmacol Toxicol (2008) 3.10
Kidney injury molecule-1 outperforms traditional biomarkers of kidney injury in preclinical biomarker qualification studies. Nat Biotechnol (2010) 3.07
Improved performance of urinary biomarkers of acute kidney injury in the critically ill by stratification for injury duration and baseline renal function. Kidney Int (2011) 3.05
Chronic epithelial kidney injury molecule-1 expression causes murine kidney fibrosis. J Clin Invest (2013) 3.03
Urinary biomarkers in the clinical prognosis and early detection of acute kidney injury. Clin J Am Soc Nephrol (2010) 3.03
Urinary biomarkers for sensitive and specific detection of acute kidney injury in humans. Clin Transl Sci (2008) 2.98
Creatinine kinetics and the definition of acute kidney injury. J Am Soc Nephrol (2009) 2.96
Heavy metal--rely on gut feelings: novel diagnostic approach to test drug compliance in patients with lanthanum intake. Nephrol Dial Transplant (2007) 2.96
Wegener's granulomatosis. Lancet (2006) 2.83
Resolvin D series and protectin D1 mitigate acute kidney injury. J Immunol (2006) 2.75
Targeted proximal tubule injury triggers interstitial fibrosis and glomerulosclerosis. Kidney Int (2012) 2.74
Pathogenesis and management of hypertension after kidney transplantation. J Hypertens (2011) 2.66
Immunosuppressive treatment protects against angiotensin II-induced renal damage. Am J Pathol (2002) 2.50
Acute renal failure in zebrafish: a novel system to study a complex disease. Am J Physiol Renal Physiol (2004) 2.50
A rapid urine test for early detection of kidney injury. Kidney Int (2009) 2.50
Kidney tubular epithelium is restored without replacement with bone marrow-derived cells during repair after ischemic injury. Kidney Int (2005) 2.43
Carotid baroreceptor stimulation, sympathetic activity, baroreflex function, and blood pressure in hypertensive patients. Hypertension (2010) 2.38
Conditional ablation of macrophages halts progression of crescentic glomerulonephritis. Am J Pathol (2005) 2.38
Shedding of kidney injury molecule-1, a putative adhesion protein involved in renal regeneration. J Biol Chem (2002) 2.36
Mesenchymal stem cells in acute kidney injury. Annu Rev Med (2008) 2.33
Validation of treatment strategies for enterohaemorrhagic Escherichia coli O104:H4 induced haemolytic uraemic syndrome: case-control study. BMJ (2012) 2.32
Circulating miR-210 predicts survival in critically ill patients with acute kidney injury. Clin J Am Soc Nephrol (2011) 2.27
Repair of injured proximal tubule does not involve specialized progenitors. Proc Natl Acad Sci U S A (2011) 2.22
Erythropoietin regulates endothelial progenitor cells. Blood (2003) 2.18
AT1 receptor agonistic antibodies from preeclamptic patients stimulate NADPH oxidase. Circulation (2003) 2.15
Kidney injury molecule-1 (KIM-1): a urinary biomarker and much more. Nephrol Dial Transplant (2009) 2.12
Cardiovascular effects of systemic nitric oxide synthase inhibition with asymmetrical dimethylarginine in humans. Circulation (2003) 2.12
Phospholipase A2 reduction ameliorates cognitive deficits in a mouse model of Alzheimer's disease. Nat Neurosci (2008) 2.09
Effect of renin-angiotensin-aldosterone system inhibition, dietary sodium restriction, and/or diuretics on urinary kidney injury molecule 1 excretion in nondiabetic proteinuric kidney disease: a post hoc analysis of a randomized controlled trial. Am J Kidney Dis (2008) 2.05
High urinary excretion of kidney injury molecule-1 is an independent predictor of graft loss in renal transplant recipients. Transplantation (2007) 2.01
Stimulation of endothelial progenitor cells: a new putative therapeutic effect of angiotensin II receptor antagonists. Hypertension (2005) 2.01
Circulating endothelial cells as markers for ANCA-associated small-vessel vasculitis. Lancet (2003) 2.00
Asymmetric dimethylarginine and progression of chronic kidney disease: the mild to moderate kidney disease study. J Am Soc Nephrol (2005) 2.00
Tissue array technology for testing interlaboratory and interobserver reproducibility of immunohistochemical estrogen receptor analysis in a large multicenter trial. Am J Clin Pathol (2002) 1.99
Reappraisal of European guidelines on hypertension management: a European Society of Hypertension Task Force document. Blood Press (2009) 1.98
Testosterone is responsible for enhanced susceptibility of males to ischemic renal injury. J Biol Chem (2004) 1.96
Renal cell carcinoma in transplant recipients with acquired cystic kidney disease. Clin J Am Soc Nephrol (2007) 1.95
Comparison of kidney injury molecule-1 and other nephrotoxicity biomarkers in urine and kidney following acute exposure to gentamicin, mercury, and chromium. Toxicol Sci (2007) 1.94
Renal injury is a third hit promoting rapid development of adult polycystic kidney disease. Hum Mol Genet (2009) 1.94
Urinary liver-type fatty acid-binding protein predicts adverse outcomes in acute kidney injury. Kidney Int (2009) 1.94
Excess circulating angiopoietin-2 is a strong predictor of mortality in critically ill medical patients. Crit Care (2008) 1.94
Cytosolic phospholipase A2alpha is crucial [correction of A2alpha deficiency is crucial] for 'on-time' embryo implantation that directs subsequent development. Development (2002) 1.91
The miRNA-212/132 family regulates both cardiac hypertrophy and cardiomyocyte autophagy. Nat Commun (2012) 1.88
The Hannover Dialysis Outcome study: comparison of standard versus intensified extended dialysis for treatment of patients with acute kidney injury in the intensive care unit. Nephrol Dial Transplant (2009) 1.86
Loss of podocyte aPKClambda/iota causes polarity defects and nephrotic syndrome. J Am Soc Nephrol (2009) 1.86
Tubular kidney injury molecule-1 in protein-overload nephropathy. Am J Physiol Renal Physiol (2006) 1.85
Lung-targeted RNA interference against angiopoietin-2 ameliorates multiple organ dysfunction and death in sepsis. Crit Care Med (2014) 1.83
Nephrogenesis is induced by partial nephrectomy in the elasmobranch Leucoraja erinacea. J Am Soc Nephrol (2003) 1.83
Novel baroreflex activation therapy in resistant hypertension: results of a European multi-center feasibility study. J Am Coll Cardiol (2010) 1.82
Antiinflammatory effects of angiotensin II subtype 1 receptor blockade in hypertensive patients with microinflammation. Circulation (2004) 1.81
KIM-1-mediated phagocytosis reduces acute injury to the kidney. J Clin Invest (2015) 1.80
Protocol biopsy of the stable renal transplant: a multicenter study of methods and complication rates. Transplantation (2003) 1.79
Activated renal macrophages are markers of disease onset and disease remission in lupus nephritis. J Immunol (2008) 1.79
Imperfect gold standards for kidney injury biomarker evaluation. J Am Soc Nephrol (2011) 1.79
Protection of renal epithelial cells against oxidative injury by endoplasmic reticulum stress preconditioning is mediated by ERK1/2 activation. J Biol Chem (2003) 1.78
Comparative analysis of urinary biomarkers for early detection of acute kidney injury following cardiopulmonary bypass. Biomarkers (2009) 1.77
Urinary podocyte excretion as a marker for preeclampsia. Am J Obstet Gynecol (2007) 1.75
Biologic markers for the early detection of acute kidney injury. Curr Opin Crit Care (2004) 1.75
Renal insulin resistance syndrome, adiponectin and cardiovascular events in patients with kidney disease: the mild and moderate kidney disease study. J Am Soc Nephrol (2005) 1.74
Endothelial-vasoprotective effects of high-density lipoprotein are impaired in patients with type 2 diabetes mellitus but are improved after extended-release niacin therapy. Circulation (2009) 1.73
Release of free F2-isoprostanes from esterified phospholipids is catalyzed by intracellular and plasma platelet-activating factor acetylhydrolases. J Biol Chem (2005) 1.73
Complement 5a receptor inhibition improves renal allograft survival. J Am Soc Nephrol (2008) 1.72
Human kidney injury molecule-1 is a tissue and urinary tumor marker of renal cell carcinoma. J Am Soc Nephrol (2005) 1.71
Marked increase of asymmetric dimethylarginine in patients with incipient primary chronic renal disease. J Am Soc Nephrol (2002) 1.70
Regression of microalbuminuria in type 1 diabetes is associated with lower levels of urinary tubular injury biomarkers, kidney injury molecule-1, and N-acetyl-β-D-glucosaminidase. Kidney Int (2010) 1.67
MicroRNAs as mediators and therapeutic targets in chronic kidney disease. Nat Rev Nephrol (2011) 1.65
Kidney injury molecule-1 expression in murine polycystic kidney disease. Am J Physiol Renal Physiol (2002) 1.64
Inducible nitric-oxide synthase is an important contributor to prolonged protective effects of ischemic preconditioning in the mouse kidney. J Biol Chem (2003) 1.63
Asymmetric dimethylarginine, blood pressure, and renal perfusion in elderly subjects. Circulation (2003) 1.63
Urine protein patterns can serve as diagnostic tools in patients with IgA nephropathy. Kidney Int (2005) 1.63
A molecular classifier for predicting future graft loss in late kidney transplant biopsies. J Clin Invest (2010) 1.61
A wild zebra chase. Nephrol Dial Transplant (2007) 1.60
Gnotobiotic piglets develop thrombotic microangiopathy after oral infection with enterohemorrhagic Escherichia coli. Am J Clin Pathol (2002) 1.59
Pathophysiology of acute kidney injury to chronic kidney disease: maladaptive repair. Contrib Nephrol (2011) 1.57