Published in Annu Rev Pharmacol Toxicol on January 01, 2008
Cellular pathophysiology of ischemic acute kidney injury. J Clin Invest (2011) 5.75
Urinary biomarkers for sensitive and specific detection of acute kidney injury in humans. Clin Transl Sci (2008) 2.98
Next-generation biomarkers for detecting kidney toxicity. Nat Biotechnol (2010) 2.64
Acute kidney injury in patients with acute lung injury: impact of fluid accumulation on classification of acute kidney injury and associated outcomes. Crit Care Med (2011) 2.55
A rapid urine test for early detection of kidney injury. Kidney Int (2009) 2.50
Regression of microalbuminuria in type 1 diabetes is associated with lower levels of urinary tubular injury biomarkers, kidney injury molecule-1, and N-acetyl-β-D-glucosaminidase. Kidney Int (2010) 1.67
Assay validation for KIM-1: human urinary renal dysfunction biomarker. Int J Biol Sci (2009) 1.49
Biomarkers of Kidney Injury Among Nicaraguan Sugarcane Workers. Am J Kidney Dis (2015) 1.46
Emerging role of autophagy in kidney function, diseases and aging. Autophagy (2012) 1.43
MicroRNA: a new frontier in kidney and blood pressure research. Am J Physiol Renal Physiol (2009) 1.41
Urinary NGAL marks cystic disease in HIV-associated nephropathy. J Am Soc Nephrol (2009) 1.34
A basic science view of acute kidney injury biomarkers. Nephrol Dial Transplant (2014) 1.33
Urinary biomarkers for the early diagnosis of kidney cancer. Mayo Clin Proc (2010) 1.24
Cell-specific translational profiling in acute kidney injury. J Clin Invest (2014) 1.23
Etiopathology of chronic tubular, glomerular and renovascular nephropathies: clinical implications. J Transl Med (2011) 1.18
Emerging urinary biomarkers in the diagnosis of acute kidney injury. Expert Opin Med Diagn (2008) 1.15
Ischemic kidney injury and mechanisms of tissue repair. Wiley Interdiscip Rev Syst Biol Med (2010) 1.06
Human miRNome profiling identifies microRNAs differentially present in the urine after kidney injury. Clin Chem (2013) 1.04
Dynamic noninvasive monitoring of renal function in vivo by fluorescence lifetime imaging. J Biomed Opt (2009) 1.04
Genetic disruption of Abl nuclear import reduces renal apoptosis in a mouse model of cisplatin-induced nephrotoxicity. Cell Death Differ (2013) 1.00
Mechanisms of cadmium-induced proximal tubule injury: new insights with implications for biomonitoring and therapeutic interventions. J Pharmacol Exp Ther (2012) 0.99
Applying new diagnostic criteria for acute kidney injury to facilitate early identification of nephrotoxicity in vancomycin-treated patients. Antimicrob Agents Chemother (2011) 0.97
Expression of kidney injury molecule-1 (Kim-1) in relation to necrosis and apoptosis during the early stages of Cd-induced proximal tubule injury. Toxicol Appl Pharmacol (2009) 0.97
Gene expression analysis reveals new possible mechanisms of vancomycin-induced nephrotoxicity and identifies gene markers candidates. Toxicol Sci (2008) 0.96
Changes in the concentrations of creatinine, cystatin C and NGAL in patients with acute paraquat self-poisoning. Toxicol Lett (2011) 0.96
Multipotent stem cells in the Malpighian tubules of adult Drosophila melanogaster. J Exp Biol (2009) 0.96
The application of mass-spectrometry-based protein biomarker discovery to theragnostics. Br J Clin Pharmacol (2010) 0.91
Identification of tubular injury microRNA biomarkers in urine: comparison of next-generation sequencing and qPCR-based profiling platforms. BMC Genomics (2014) 0.91
Use of the kidney injury molecule-1 as a biomarker for early detection of renal tubular dysfunction in a population chronically exposed to cadmium in the environment. Springerplus (2013) 0.91
The association between urinary kidney injury molecule 1 and urinary cadmium in elderly during long-term, low-dose cadmium exposure: a pilot study. Environ Health (2011) 0.88
Fibrinogen excretion in the urine and immunoreactivity in the kidney serves as a translational biomarker for acute kidney injury. Am J Pathol (2012) 0.88
Preclinical evaluation of novel urinary biomarkers of cadmium nephrotoxicity. Toxicol Appl Pharmacol (2009) 0.87
Collective epithelial migration drives kidney repair after acute injury. PLoS One (2014) 0.86
Embolization of hypervascular bone metastases reduces intraoperative blood loss: a case-control study. Clin Orthop Relat Res (2014) 0.86
The future of pediatric acute kidney injury management--biomarkers. Semin Nephrol (2008) 0.86
Heart-kidney biomarkers in patients undergoing cardiac stress testing. Int J Nephrol (2010) 0.86
Effects of valproic acid and dexamethasone administration on early bio-markers and gene expression profile in acute kidney ischemia-reperfusion injury in the rat. PLoS One (2015) 0.85
Proteomics and metabolomics in renal transplantation-quo vadis? Transpl Int (2012) 0.85
Urinary glutathione S-transferases in the pathogenesis and diagnostic evaluation of acute kidney injury following cardiac surgery: a critical review. Curr Opin Crit Care (2010) 0.85
Sepsis and AKI in ICU Patients: The Role of Plasma Biomarkers. Crit Care Res Pract (2012) 0.85
Emergence of biomarkers in nephropharmacology. Biomark Med (2010) 0.84
Urinary N-acetyl-β-D glucosaminidase as a surrogate marker for renal function in autosomal dominant polycystic kidney disease: 1 year prospective cohort study. BMC Nephrol (2012) 0.84
Elevated Vancomycin Trough Concentration: Increased Efficacy and/or Toxicity? Iran J Pharm Res (2014) 0.83
OMA1 mediates OPA1 proteolysis and mitochondrial fragmentation in experimental models of ischemic kidney injury. Am J Physiol Renal Physiol (2014) 0.83
Proteomic analysis of acute kidney injury: biomarkers to mechanisms. Proteomics Clin Appl (2010) 0.82
Proteomic candidate biomarkers of drug-induced nephrotoxicity in the rat. PLoS One (2012) 0.82
Mechanisms for an effect of acetylcysteine on renal function after exposure to radio-graphic contrast material: study protocol. BMC Clin Pharmacol (2012) 0.81
Urinary aminopeptidase activities as early and predictive biomarkers of renal dysfunction in cisplatin-treated rats. PLoS One (2012) 0.81
Current and novel renal biomarkers in heart failure. Heart Fail Rev (2012) 0.81
The current status of biomarkers for predicting toxicity. Expert Opin Drug Metab Toxicol (2013) 0.81
Urinary biomarkers track the progression of nephropathy in hypertensive and obese rats. Biomark Med (2014) 0.81
Evaluation of cystatin C as an early biomarker of cadmium nephrotoxicity in the rat. Biometals (2015) 0.81
Drug-induced nephrotoxicity and its biomarkers. Biomol Ther (Seoul) (2012) 0.80
Acute kidney injury: the beginning of the end of the dark ages. Am J Med Sci (2012) 0.80
Biomarkers of immunosuppressant organ toxicity after transplantation: status, concepts and misconceptions. Expert Opin Drug Metab Toxicol (2011) 0.80
Urinary neutrophil gelatinase-associated lipocalin: a useful biomarker for tacrolimus-induced acute kidney injury in liver transplant patients. PLoS One (2014) 0.80
Selenium inhibits renal oxidation and inflammation but not acute kidney injury in an animal model of rhabdomyolysis. Antioxid Redox Signal (2012) 0.80
Kidney injury molecule-1 as a predicting factor for inflamed kidney, diabetic and diabetic nephropathy Egyptian patients. J Diabetes Metab Disord (2015) 0.79
Urinary kidney injury molecule-1 and the risk of cardiovascular mortality in elderly men. Clin J Am Soc Nephrol (2014) 0.79
Measurement of renal function in patients with chronic kidney disease. Br J Clin Pharmacol (2013) 0.79
Acute pretreatment with chloroquine attenuates renal I/R injury in rats. PLoS One (2014) 0.78
Detection of Drug-Induced Acute Kidney Injury in Humans Using Urinary KIM-1, miR-21, -200c, and -423. Toxicol Sci (2016) 0.78
Nanosized contrast agents to noninvasively detect kidney inflammation by magnetic resonance imaging. Adv Chronic Kidney Dis (2013) 0.78
Microelectromechanical systems and nephrology: the next frontier in renal replacement technology. Adv Chronic Kidney Dis (2013) 0.77
Assessment of urinary kidney injury molecule-1 and interleukin-18 in the early post-burn period to predict acute kidney injury for various degrees of burn injury. BMC Nephrol (2015) 0.77
Molecular determinants of acute kidney injury. J Inj Violence Res (2015) 0.77
Cerium oxide nanoparticles attenuate acute kidney injury induced by intra-abdominal infection in Sprague-Dawley rats. J Nanobiotechnology (2015) 0.76
Role of biomarkers of nephrotoxic acute kidney injury in deliberate poisoning and envenomation in less developed countries. Br J Clin Pharmacol (2015) 0.76
Nanoparticle Detection of Urinary Markers for Point-of-Care Diagnosis of Kidney Injury. PLoS One (2015) 0.76
3D Proximal Tubule Tissues Recapitulate Key Aspects of Renal Physiology to Enable Nephrotoxicity Testing. Front Physiol (2017) 0.75
Hypertension and hyperglycemia synergize to cause incipient renal tubular alterations resulting in increased NGAL urinary excretion in rats. PLoS One (2014) 0.75
Effects of carnitine on oxidative stress response to intravenous iron administration to patients with CKD: impact of haptoglobin phenotype. BMC Nephrol (2015) 0.75
Kidney injury molecule-1 and microalbuminuria levels in Zambian population: biomarkers of kidney injury. Pan Afr Med J (2016) 0.75
Expression and Function of Interleukin-1β-Induced Neutrophil Gelatinase-Associated Lipocalin in Renal Tubular Cells. PLoS One (2016) 0.75
Acute Kidney Injury: Diagnostic Approaches and Controversies. Clin Biochem Rev (2016) 0.75
Potential Biomarkers for Radiation-Induced Renal Toxicity following 177Lu-Octreotate Administration in Mice. PLoS One (2015) 0.75
Performance of urinary and gene expression biomarkers in detecting the nephrotoxic effects of melamine and cyanuric acid following diverse scenarios of co-exposure. Food Chem Toxicol (2012) 0.75
Challenges facing early detection of acute kidney injury in the critically ill. World J Crit Care Med (2012) 0.75
Early Detection of Drug-Induced Renal Hemodynamic Dysfunction Using Sonographic Technology in Rats. J Vis Exp (2016) 0.75
Mining kidney toxicogenomic data by using gene co-expression modules. BMC Genomics (2016) 0.75
Urinary Kidney Injury Molecules in Children with Iron-Deficiency Anemia. Med Sci Monit (2015) 0.75
Adaptive Bayesian approach to clinical trial renal impairment biomarker signal from urea and creatinine. Int J Biol Sci (2013) 0.75
Evaluation of retinol binding protein 4 and carbamoylated haemoglobin as potential renal toxicity biomarkers in adult mice treated with (177)Lu-octreotate. EJNMMI Res (2014) 0.75
Pharmacokinetics and Renal Toxicity of Monomeric Amphotericin B in Rats after a Multiple Dose Regimen. Pharm Nanotechnol (2016) 0.75
Single-Multiplex Detection of Organ Injury Biomarkers using SPRi based Nano-Immunosensor. Sci Rep (2016) 0.75
Urinary MCP1 and Microalbumin increase prior to onset of Azotemia in mice with polycystic kidney disease. Comp Med (2014) 0.75
Evaluation of clinically available renal biomarkers in critically ill adults: a prospective multicenter observational study. Crit Care (2017) 0.75
Pyruvate Kinase M2: A Novel Biomarker for the Early Detection of Acute Kidney Injury. Toxicol Res (2016) 0.75
Elevated urinary levels of cystatin C and neutrophil gelatinase-associated lipocalin in Henoch-Schönlein purpura patients with renal involvement. PLoS One (2014) 0.75
Nicotine Mediates CD161a+ Renal Macrophage Infiltration and Premature Hypertension in the Spontaneously Hypertensive Rat. Circ Res (2016) 0.75
Storage Time and Urine Biomarker Levels in the ASSESS-AKI Study. PLoS One (2016) 0.75
Glutamyl aminopeptidase in microvesicular and exosomal fractions of urine is related with renal dysfunction in cisplatin-treated rats. PLoS One (2017) 0.75
Pathogenesis of Type 2 Epithelial to Mesenchymal Transition (EMT) in Renal and Hepatic Fibrosis. J Clin Med (2015) 0.75
Molecular characterization of the transition from acute to chronic kidney injury following ischemia/reperfusion. JCI Insight (2017) 0.75
Effects of phosphodiesterase-5 inhibitor on ischemic kidney injury during nephron sparing surgery: quantitative assessment by NGAL and KIM-1. World J Urol (2015) 0.75
Urine clusterin/apolipoprotein J is linked to tubular damage and renal outcomes in patients with type 2 diabetes mellitus. Clin Endocrinol (Oxf) (2017) 0.75
Cadmium Handling, Toxicity and Molecular Targets Involved during Pregnancy: Lessons from Experimental Models. Int J Mol Sci (2017) 0.75
Acute Kidney Injury Network: report of an initiative to improve outcomes in acute kidney injury. Crit Care (2007) 29.89
Acute renal failure in critically ill patients: a multinational, multicenter study. JAMA (2005) 19.57
Cystatin C and the risk of death and cardiovascular events among elderly persons. N Engl J Med (2005) 15.30
Protein biomarker discovery and validation: the long and uncertain path to clinical utility. Nat Biotechnol (2006) 10.14
Identification of neutrophil gelatinase-associated lipocalin as a novel early urinary biomarker for ischemic renal injury. J Am Soc Nephrol (2003) 9.08
Acute renal failure. N Engl J Med (1996) 8.83
Kidney Injury Molecule-1 (KIM-1): a novel biomarker for human renal proximal tubule injury. Kidney Int (2002) 8.03
Multiplexed electrical detection of cancer markers with nanowire sensor arrays. Nat Biotechnol (2005) 8.00
Hospital-acquired renal insufficiency. Am J Kidney Dis (2002) 7.90
The normal kidney filters nephrotic levels of albumin retrieved by proximal tubule cells: retrieval is disrupted in nephrotic states. Kidney Int (2007) 6.99
Declining mortality in patients with acute renal failure, 1988 to 2002. J Am Soc Nephrol (2006) 6.66
Epidemiology and outcomes of acute renal failure in hospitalized patients: a national survey. Clin J Am Soc Nephrol (2005) 6.27
Guided medication dosing for inpatients with renal insufficiency. JAMA (2001) 6.25
Kidney injury molecule-1 (KIM-1), a putative epithelial cell adhesion molecule containing a novel immunoglobulin domain, is up-regulated in renal cells after injury. J Biol Chem (1998) 5.99
Endocytic delivery of lipocalin-siderophore-iron complex rescues the kidney from ischemia-reperfusion injury. J Clin Invest (2005) 5.51
Multiplexed particle-based flow cytometric assays. J Immunol Methods (2000) 5.09
Treatment of acute renal failure. Kidney Int (1998) 4.75
Acute renal failure in the ICU: risk factors and outcome evaluated by the SOFA score. Intensive Care Med (2000) 4.74
Ischemic acute renal failure: an inflammatory disease? Kidney Int (2004) 4.33
Simultaneous measurement of beta-amyloid(1-42), total tau, and phosphorylated tau (Thr181) in cerebrospinal fluid by the xMAP technology. Clin Chem (2004) 4.23
Recent advances in the pathophysiology of ischemic acute renal failure. J Am Soc Nephrol (2003) 3.99
Urinary kidney injury molecule-1: a sensitive quantitative biomarker for early detection of kidney tubular injury. Am J Physiol Renal Physiol (2005) 3.94
Lipocalin 2-deficient mice exhibit increased sensitivity to Escherichia coli infection but not to ischemia-reperfusion injury. Proc Natl Acad Sci U S A (2006) 3.85
Acute renal failure: definitions, diagnosis, pathogenesis, and therapy. J Clin Invest (2004) 3.75
Association between increases in urinary neutrophil gelatinase-associated lipocalin and acute renal dysfunction after adult cardiac surgery. Anesthesiology (2006) 3.66
The lipocalin protein family: structural and sequence overview. Biochim Biophys Acta (2000) 3.48
Urinary N-acetyl-beta-(D)-glucosaminidase activity and kidney injury molecule-1 level are associated with adverse outcomes in acute renal failure. J Am Soc Nephrol (2007) 3.48
Dedifferentiation and proliferation of surviving epithelial cells in acute renal failure. J Am Soc Nephrol (2003) 3.47
Urine IL-18 is an early diagnostic marker for acute kidney injury and predicts mortality in the intensive care unit. J Am Soc Nephrol (2005) 3.38
Urinary interleukin-18 is a marker of human acute tubular necrosis. Am J Kidney Dis (2004) 3.35
Molecular characterization and pattern of tissue expression of the gene for neutrophil gelatinase-associated lipocalin from humans. Genomics (1997) 3.16
Collection, storage, preservation, and normalization of human urinary exosomes for biomarker discovery. Kidney Int (2006) 3.00
On-pump versus off-pump coronary revascularization: evaluation of renal function. Ann Thorac Surg (1999) 2.94
Neutrophil gelatinase-associated lipocalin: a novel early urinary biomarker for cisplatin nephrotoxicity. Am J Nephrol (2004) 2.91
Acute renal failure definitions and classification: time for change? J Am Soc Nephrol (2003) 2.81
Interleukin-18. J Leukoc Biol (2003) 2.75
Simultaneous quantitation of 15 cytokines using a multiplexed flow cytometric assay. J Immunol Methods (1999) 2.73
Fabrication of silicon nanowire devices for ultrasensitive, label-free, real-time detection of biological and chemical species. Nat Protoc (2006) 2.73
Course of acute renal failure studied by a model of creatinine kinetics. Kidney Int (1985) 2.69
Tubular kidney injury molecule-1 (KIM-1) in human renal disease. J Pathol (2007) 2.63
Induction of NGAL synthesis in epithelial cells of human colorectal neoplasia and inflammatory bowel diseases. Gut (1996) 2.63
Serum cystatin C, determined by a rapid, automated particle-enhanced turbidimetric method, is a better marker than serum creatinine for glomerular filtration rate. Clin Chem (1994) 2.62
Urinary measurement of Na+/H+ exchanger isoform 3 (NHE3) protein as new marker of tubule injury in critically ill patients with ARF. Am J Kidney Dis (2003) 2.56
Exosomal Fetuin-A identified by proteomics: a novel urinary biomarker for detecting acute kidney injury. Kidney Int (2006) 2.44
Shedding of kidney injury molecule-1, a putative adhesion protein involved in renal regeneration. J Biol Chem (2002) 2.36
Mesenchymal stem cells in acute kidney injury. Annu Rev Med (2008) 2.33
Cellular fatty acid-binding proteins: their function and physiological significance. Prog Lipid Res (1996) 2.24
Developing a consensus classification system for acute renal failure. Curr Opin Crit Care (2002) 2.24
Prognostic value of tubular proteinuria and enzymuria in nonoliguric acute tubular necrosis. Clin Chem (2004) 2.10
Urinary neutrophil gelatinase-associated lipocalcin in D+HUS: a novel marker of renal injury. Pediatr Nephrol (2006) 2.09
Label-free detection of small-molecule-protein interactions by using nanowire nanosensors. Proc Natl Acad Sci U S A (2005) 1.95
Measurement of tubular enzymuria facilitates early detection of acute renal impairment in the intensive care unit. Nephrol Dial Transplant (2003) 1.94
Challenge and promise: roles for clusterin in pathogenesis, progression and therapy of cancer. Cell Death Differ (2006) 1.83
Advances in urinary proteome analysis and biomarker discovery. J Am Soc Nephrol (2007) 1.77
Rapid isolation of urinary exosomal biomarkers using a nanomembrane ultrafiltration concentrator. Am J Physiol Renal Physiol (2007) 1.72
Tissue distribution and activity testing suggest a similar but not identical function of fetuin-B and fetuin-A. Biochem J (2003) 1.72
Expression, roles, receptors, and regulation of osteopontin in the kidney. Kidney Int (2001) 1.66
Purification and characterization of a cell-aggregating factor (clusterin), the major glycoprotein in ram rete testis fluid. J Biol Chem (1983) 1.64
Inducible nitric-oxide synthase is an important contributor to prolonged protective effects of ischemic preconditioning in the mouse kidney. J Biol Chem (2003) 1.63
The metabolic significance of mammalian fatty-acid-binding proteins: abundant proteins in search of a function. Annu Rev Nutr (1987) 1.63
Drug-associated renal dysfunction and injury. Nat Clin Pract Nephrol (2006) 1.60
Urinary excretion of fatty acid-binding protein reflects stress overload on the proximal tubules. Am J Pathol (2004) 1.56
Cyr61, product of a growth factor-inducible immediate early gene, is associated with the extracellular matrix and the cell surface. Cell Growth Differ (1991) 1.55
Serum measurements of human neutrophil lipocalin (HNL) discriminate between acute bacterial and viral infections. Scand J Clin Lab Invest (1995) 1.51
Urinary fatty acid-binding protein as a new clinical marker of the progression of chronic renal disease. J Lab Clin Med (2004) 1.48
Mechanism of proximal tubule bicarbonate absorption in NHE3 null mice. Am J Physiol (1999) 1.47
Kidney injury molecule-1 is an early biomarker of cadmium nephrotoxicity. Kidney Int (2007) 1.46
Serum cystatin C--a superior marker of rapidly reduced glomerular filtration after uninephrectomy in kidney donors compared to creatinine. Clin Nephrol (2005) 1.43
Measurement of cystatin-C and creatinine in urine. Clin Chim Acta (2002) 1.41
Proteomic-based identification of cleaved urinary beta2-microglobulin as a potential marker for acute tubular injury in renal allografts. Am J Transplant (2005) 1.39
Polarity, integrin, and extracellular matrix dynamics in the postischemic rat kidney. Am J Physiol (1998) 1.38
Assessment of urinary retinol-binding protein as an index of proximal tubular injury. Clin Chem (1987) 1.36
Molecular identification of the liver- and the heart-type fatty acid-binding proteins in human and rat kidney. Use of the reverse transcriptase polymerase chain reaction. Biochem J (1992) 1.35
beta 2-Microglobulin instability in pathological urine. Clin Chem (1982) 1.31
Urinary cystatin C as a specific marker of tubular dysfunction. Clin Chem Lab Med (2006) 1.31
Biosynthesis of granule proteins in normal human bone marrow cells. Gelatinase is a marker of terminal neutrophil differentiation. Blood (1995) 1.30
Tubular osteopontin expression in human glomerulonephritis and renal vasculitis. Am J Kidney Dis (2000) 1.29
Mechanistic biomarkers for cytotoxic acute kidney injury. Expert Opin Drug Metab Toxicol (2006) 1.24
Urinary liver-type fatty acid binding protein as a useful biomarker in chronic kidney disease. Mol Cell Biochem (2006) 1.22
Two types of fatty acid-binding protein in human kidney. Isolation, characterization and localization. Biochem J (1991) 1.20
Elevation of CXCR3-binding chemokines in urine indicates acute renal-allograft dysfunction. Am J Transplant (2004) 1.19
Urinary protein and enzyme excretion as markers of tubular damage. Curr Opin Nephrol Hypertens (2003) 1.18
The CCN family of genes: a brief history. Mol Pathol (2001) 1.18
Contribution of human uropontin to inhibition of calcium oxalate crystallization. Kidney Int (1998) 1.15
Purification of a factor which provides a costimulatory signal for gamma interferon production. Infect Immun (1993) 1.14
Increased circulating levels of proteinase 3 in patients with anti-neutrophilic cytoplasmic autoantibodies-associated systemic vasculitis in remission. Clin Exp Immunol (2003) 1.13
Urinary excretion of liver-type fatty acid-binding protein in contrast medium-induced nephropathy. Am J Kidney Dis (2006) 1.10
Early detection of cysteine rich protein 61 (CYR61, CCN1) in urine following renal ischemic reperfusion injury. Kidney Int (2002) 1.09
Beta-2 microglobulin in renal disease. J Am Soc Nephrol (1998) 1.08
Alpha 1-microglobulin: clinical laboratory aspects and applications. Clin Chim Acta (2004) 1.08
Overexpression of chemokines, fibrogenic cytokines, and myofibroblasts in human membranous nephropathy. Kidney Int (2000) 1.08
Detection of Na(+) transporter proteins in urine. J Am Soc Nephrol (2000) 1.07
The contribution of adult stem cells to renal repair. Nephrol Ther (2007) 1.06
The role of interleukin-18 in renal injury. J Surg Res (2007) 1.05
Interleukin-18 (IL-18) and infectious diseases, with special emphasis on diseases induced by intracellular pathogens. Microbes Infect (2000) 1.02
Interleukin 18 (IL-18) upregulation in acute rejection of kidney allograft. Immunol Lett (2005) 1.02
Osteopontin expression in human crescentic glomerulonephritis. Kidney Int (2000) 0.99
The SGP-2 gene is developmentally regulated in the mouse kidney and abnormally expressed in collecting duct cysts in polycystic kidney disease. Dev Biol (1991) 0.99
Acute kidney injury, mortality, length of stay, and costs in hospitalized patients. J Am Soc Nephrol (2005) 18.76
Kidney Injury Molecule-1 (KIM-1): a novel biomarker for human renal proximal tubule injury. Kidney Int (2002) 8.03
Fate tracing reveals the pericyte and not epithelial origin of myofibroblasts in kidney fibrosis. Am J Pathol (2009) 7.34
Intrinsic epithelial cells repair the kidney after injury. Cell Stem Cell (2008) 6.54
Epithelial cell cycle arrest in G2/M mediates kidney fibrosis after injury. Nat Med (2010) 4.76
Restoration of tubular epithelial cells during repair of the postischemic kidney occurs independently of bone marrow-derived stem cells. J Clin Invest (2005) 4.10
Urinary kidney injury molecule-1: a sensitive quantitative biomarker for early detection of kidney tubular injury. Am J Physiol Renal Physiol (2005) 3.94
Normalization of urinary biomarkers to creatinine during changes in glomerular filtration rate. Kidney Int (2010) 3.78
Kidney injury molecule-1: a tissue and urinary biomarker for nephrotoxicant-induced renal injury. Am J Physiol Renal Physiol (2003) 3.61
Kidney injury molecule-1 is a phosphatidylserine receptor that confers a phagocytic phenotype on epithelial cells. J Clin Invest (2008) 3.59
Urinary N-acetyl-beta-(D)-glucosaminidase activity and kidney injury molecule-1 level are associated with adverse outcomes in acute renal failure. J Am Soc Nephrol (2007) 3.48
Kidney injury molecule-1 outperforms traditional biomarkers of kidney injury in preclinical biomarker qualification studies. Nat Biotechnol (2010) 3.07
Improved performance of urinary biomarkers of acute kidney injury in the critically ill by stratification for injury duration and baseline renal function. Kidney Int (2011) 3.05
Chronic epithelial kidney injury molecule-1 expression causes murine kidney fibrosis. J Clin Invest (2013) 3.03
Urinary biomarkers in the clinical prognosis and early detection of acute kidney injury. Clin J Am Soc Nephrol (2010) 3.03
Urinary biomarkers for sensitive and specific detection of acute kidney injury in humans. Clin Transl Sci (2008) 2.98
Creatinine kinetics and the definition of acute kidney injury. J Am Soc Nephrol (2009) 2.96
Resolvin D series and protectin D1 mitigate acute kidney injury. J Immunol (2006) 2.75
Targeted proximal tubule injury triggers interstitial fibrosis and glomerulosclerosis. Kidney Int (2012) 2.74
Acute renal failure in zebrafish: a novel system to study a complex disease. Am J Physiol Renal Physiol (2004) 2.50
A rapid urine test for early detection of kidney injury. Kidney Int (2009) 2.50
Kidney tubular epithelium is restored without replacement with bone marrow-derived cells during repair after ischemic injury. Kidney Int (2005) 2.43
Conditional ablation of macrophages halts progression of crescentic glomerulonephritis. Am J Pathol (2005) 2.38
Shedding of kidney injury molecule-1, a putative adhesion protein involved in renal regeneration. J Biol Chem (2002) 2.36
Mesenchymal stem cells in acute kidney injury. Annu Rev Med (2008) 2.33
Repair of injured proximal tubule does not involve specialized progenitors. Proc Natl Acad Sci U S A (2011) 2.22
Kidney injury molecule-1 (KIM-1): a urinary biomarker and much more. Nephrol Dial Transplant (2009) 2.12
Phospholipase A2 reduction ameliorates cognitive deficits in a mouse model of Alzheimer's disease. Nat Neurosci (2008) 2.09
Effect of renin-angiotensin-aldosterone system inhibition, dietary sodium restriction, and/or diuretics on urinary kidney injury molecule 1 excretion in nondiabetic proteinuric kidney disease: a post hoc analysis of a randomized controlled trial. Am J Kidney Dis (2008) 2.05
High urinary excretion of kidney injury molecule-1 is an independent predictor of graft loss in renal transplant recipients. Transplantation (2007) 2.01
Testosterone is responsible for enhanced susceptibility of males to ischemic renal injury. J Biol Chem (2004) 1.96
Comparison of kidney injury molecule-1 and other nephrotoxicity biomarkers in urine and kidney following acute exposure to gentamicin, mercury, and chromium. Toxicol Sci (2007) 1.94
Renal injury is a third hit promoting rapid development of adult polycystic kidney disease. Hum Mol Genet (2009) 1.94
Urinary liver-type fatty acid-binding protein predicts adverse outcomes in acute kidney injury. Kidney Int (2009) 1.94
Cytosolic phospholipase A2alpha is crucial [correction of A2alpha deficiency is crucial] for 'on-time' embryo implantation that directs subsequent development. Development (2002) 1.91
Tubular kidney injury molecule-1 in protein-overload nephropathy. Am J Physiol Renal Physiol (2006) 1.85
KIM-1-mediated phagocytosis reduces acute injury to the kidney. J Clin Invest (2015) 1.80
Imperfect gold standards for kidney injury biomarker evaluation. J Am Soc Nephrol (2011) 1.79
Protection of renal epithelial cells against oxidative injury by endoplasmic reticulum stress preconditioning is mediated by ERK1/2 activation. J Biol Chem (2003) 1.78
Comparative analysis of urinary biomarkers for early detection of acute kidney injury following cardiopulmonary bypass. Biomarkers (2009) 1.77
Biologic markers for the early detection of acute kidney injury. Curr Opin Crit Care (2004) 1.75
Release of free F2-isoprostanes from esterified phospholipids is catalyzed by intracellular and plasma platelet-activating factor acetylhydrolases. J Biol Chem (2005) 1.73
Human kidney injury molecule-1 is a tissue and urinary tumor marker of renal cell carcinoma. J Am Soc Nephrol (2005) 1.71
Regression of microalbuminuria in type 1 diabetes is associated with lower levels of urinary tubular injury biomarkers, kidney injury molecule-1, and N-acetyl-β-D-glucosaminidase. Kidney Int (2010) 1.67
Kidney injury molecule-1 expression in murine polycystic kidney disease. Am J Physiol Renal Physiol (2002) 1.64
Inducible nitric-oxide synthase is an important contributor to prolonged protective effects of ischemic preconditioning in the mouse kidney. J Biol Chem (2003) 1.63
Rapid screening of glomerular slit diaphragm integrity in larval zebrafish. Am J Physiol Renal Physiol (2007) 1.63
STEMI in a 24-year-old man after use of a synephrine-containing dietary supplement: a case report and review of the literature. Tex Heart Inst J (2009) 1.58
Pathophysiology of acute kidney injury to chronic kidney disease: maladaptive repair. Contrib Nephrol (2011) 1.57
Biomarkers of nephrotoxic acute kidney injury. Toxicology (2008) 1.55
Some biomarkers of acute kidney injury are increased in pre-renal acute injury. Kidney Int (2012) 1.55
Immunolocalization of Kim-1, RPA-1, and RPA-2 in kidney of gentamicin-, mercury-, or chromium-treated rats: relationship to renal distributions of iNOS and nitrotyrosine. Toxicol Pathol (2008) 1.51
T cell, Ig domain, mucin domain-2 gene-deficient mice reveal a novel mechanism for the regulation of Th2 immune responses and airway inflammation. J Immunol (2006) 1.51
Tubular damage in chronic systolic heart failure is associated with reduced survival independent of glomerular filtration rate. Heart (2010) 1.50
Mineralocorticoid receptor blockade confers renoprotection in preexisting chronic cyclosporine nephrotoxicity. Am J Physiol Renal Physiol (2006) 1.47
NADPH oxidase p22phox and catalase gene variants are associated with biomarkers of oxidative stress and adverse outcomes in acute renal failure. J Am Soc Nephrol (2006) 1.46
Urinary expression of novel tissue markers of kidney injury after ureteroscopy, shockwave lithotripsy, and in normal healthy controls. J Endourol (2013) 1.46
Modulation of aquaporin-2/vasopressin2 receptor kidney expression and tubular injury after endotoxin (lipopolysaccharide) challenge. Crit Care Med (2008) 1.44
Prevention of kidney ischemia/reperfusion-induced functional injury, MAPK and MAPK kinase activation, and inflammation by remote transient ureteral obstruction. J Biol Chem (2001) 1.43
Creatinine as the gold standard for kidney injury biomarker studies? Nephrol Dial Transplant (2009) 1.39
Induction of kidney injury molecule-1 in homozygous Ren2 rats is attenuated by blockade of the renin-angiotensin system or p38 MAP kinase. Am J Physiol Renal Physiol (2006) 1.36
Defect in regulatory B-cell function and development of systemic autoimmunity in T-cell Ig mucin 1 (Tim-1) mucin domain-mutant mice. Proc Natl Acad Sci U S A (2012) 1.35
Test characteristics of urinary biomarkers depend on quantitation method in acute kidney injury. J Am Soc Nephrol (2011) 1.35
Loss of leucine-rich repeat kinase 2 causes age-dependent bi-phasic alterations of the autophagy pathway. Mol Neurodegener (2012) 1.34
The Sweet Pee model for Sglt2 mutation. J Am Soc Nephrol (2011) 1.32
Systemic microvascular leak in an in vivo rat model of ventilator-induced lung injury. Am J Respir Crit Care Med (2003) 1.32
A highly conserved tyrosine of Tim-3 is phosphorylated upon stimulation by its ligand galectin-9. Biochem Biophys Res Commun (2006) 1.29
HIF in kidney disease and development. J Am Soc Nephrol (2008) 1.28
Regulation of HAX-1 anti-apoptotic protein by Omi/HtrA2 protease during cell death. J Biol Chem (2004) 1.28
A framework and key research questions in AKI diagnosis and staging in different environments. Clin J Am Soc Nephrol (2008) 1.27
Associations of urinary levels of kidney injury molecule 1 (KIM-1) and neutrophil gelatinase-associated lipocalin (NGAL) with kidney function decline in the Multi-Ethnic Study of Atherosclerosis (MESA). Am J Kidney Dis (2012) 1.27
Deletion of secretory group V phospholipase A2 attenuates cell migration and airway hyperresponsiveness in immunosensitized mice. J Immunol (2007) 1.25
Orchiectomy attenuates post-ischemic oxidative stress and ischemia/reperfusion injury in mice. A role for manganese superoxide dismutase. J Biol Chem (2006) 1.25
Mechanistic biomarkers for cytotoxic acute kidney injury. Expert Opin Drug Metab Toxicol (2006) 1.24
Stretch-induced IL-8 depends on c-Jun NH2-terminal and nuclear factor-kappaB-inducing kinases. Am J Physiol Lung Cell Mol Physiol (2003) 1.24
Human kidney injury molecule-1 (hKIM-1): a useful immunohistochemical marker for diagnosing renal cell carcinoma and ovarian clear cell carcinoma. Am J Surg Pathol (2007) 1.22
Nephron organoids derived from human pluripotent stem cells model kidney development and injury. Nat Biotechnol (2015) 1.21
Group V secretory phospholipase A2 translocates to the phagosome after zymosan stimulation of mouse peritoneal macrophages and regulates phagocytosis. J Biol Chem (2006) 1.20
Connectivity gradients between the default mode and attention control networks. Brain Connect (2011) 1.19
Comparative analysis of novel noninvasive renal biomarkers and metabonomic changes in a rat model of gentamicin nephrotoxicity. Toxicol Sci (2009) 1.18
Brain lipid metabolism in the cPLA2 knockout mouse. J Lipid Res (2003) 1.18
Shedding of the urinary biomarker kidney injury molecule-1 (KIM-1) is regulated by MAP kinases and juxtamembrane region. J Am Soc Nephrol (2007) 1.17
Decreased lung tumorigenesis in mice genetically deficient in cytosolic phospholipase A2. Carcinogenesis (2004) 1.16
Dialysis in acute kidney injury--more is not better. N Engl J Med (2008) 1.15
Topographic maps of multisensory attention. Proc Natl Acad Sci U S A (2010) 1.15
Reduced ciliary polycystin-2 in induced pluripotent stem cells from polycystic kidney disease patients with PKD1 mutations. J Am Soc Nephrol (2013) 1.14
Biomarkers for the diagnosis of acute kidney injury. Curr Opin Nephrol Hypertens (2007) 1.14
Signaling via macrophage G2A enhances efferocytosis of dying neutrophils by augmentation of Rac activity. J Biol Chem (2011) 1.13
Human group V phospholipase A2 induces group IVA phospholipase A2-independent cysteinyl leukotriene synthesis in human eosinophils. J Biol Chem (2003) 1.13
Reduction of proteinuria in adriamycin-induced nephropathy is associated with reduction of renal kidney injury molecule (Kim-1) over time. Am J Physiol Renal Physiol (2009) 1.11
Signaling pathways and late-onset gene induction associated with renal mesangial cell hypertrophy. EMBO J (2002) 1.11
Characterization of a novel and specific inhibitor for the pro-apoptotic protease Omi/HtrA2. J Biol Chem (2003) 1.11
Animal models of acute tubular necrosis. Curr Opin Crit Care (2002) 1.11
Ceramide 1-phosphate is required for the translocation of group IVA cytosolic phospholipase A2 and prostaglandin synthesis. J Biol Chem (2009) 1.10
Tubular expression of KIM-1 does not predict delayed function after transplantation. J Am Soc Nephrol (2009) 1.10
Onconephrology: the latest frontier in the war against kidney disease. J Am Soc Nephrol (2012) 1.10
Orchiectomy reduces susceptibility to renal ischemic injury: a role for heat shock proteins. Biochem Biophys Res Commun (2005) 1.09
The melanoma-associated transmembrane glycoprotein Gpnmb controls trafficking of cellular debris for degradation and is essential for tissue repair. FASEB J (2010) 1.09