Published in Cell Biochem Biophys on January 01, 2007
Glucolipotoxicity: fuel excess and beta-cell dysfunction. Endocr Rev (2007) 4.91
Chop deletion reduces oxidative stress, improves beta cell function, and promotes cell survival in multiple mouse models of diabetes. J Clin Invest (2008) 4.30
The unfolded protein response: a pathway that links insulin demand with beta-cell failure and diabetes. Endocr Rev (2008) 3.56
Translation attenuation through eIF2alpha phosphorylation prevents oxidative stress and maintains the differentiated state in beta cells. Cell Metab (2009) 3.28
Cellular stress responses: cell survival and cell death. Int J Cell Biol (2010) 2.74
Oxidative stress, nitric oxide, and diabetes. Rev Diabet Stud (2010) 1.43
High glucose inhibits glucose-6-phosphate dehydrogenase, leading to increased oxidative stress and beta-cell apoptosis. FASEB J (2009) 1.25
Oxidative stress and beta-cell dysfunction. Pflugers Arch (2010) 1.22
Beta-cell deterioration during diabetes: what's in the gun? Trends Endocrinol Metab (2009) 1.11
PPAR-γ activation restores pancreatic islet SERCA2 levels and prevents β-cell dysfunction under conditions of hyperglycemic and cytokine stress. Mol Endocrinol (2012) 1.10
Beta cell dysfunction and insulin resistance. Front Endocrinol (Lausanne) (2013) 1.07
Diabetes and risk of cancer. ISRN Oncol (2013) 1.06
Acute effects of dietary glycemic index on antioxidant capacity in a nutrient-controlled feeding study. Obesity (Silver Spring) (2009) 1.02
Tea consumption and risk of type 2 diabetes: a meta-analysis of cohort studies. J Gen Intern Med (2009) 1.00
PERK activation at low glucose concentration is mediated by SERCA pump inhibition and confers preemptive cytoprotection to pancreatic β-cells. Mol Endocrinol (2010) 0.89
Central role of the EGF receptor in neurometabolic aging. Int J Endocrinol (2012) 0.88
An islet in distress: β cell failure in type 2 diabetes. J Diabetes Investig (2010) 0.88
Early low protein diet aggravates unbalance between antioxidant enzymes leading to islet dysfunction. PLoS One (2009) 0.88
Alteration of mitochondrial function in adult rat offspring of malnourished dams. World J Diabetes (2011) 0.87
Associations between total serum GGT activity and metabolic risk: MESA. Biomark Med (2013) 0.86
Aldose reductase gene polymorphisms and diabetic retinopathy susceptibility. Diabetes Care (2010) 0.83
Cathepsin inhibition-induced lysosomal dysfunction enhances pancreatic beta-cell apoptosis in high glucose. PLoS One (2015) 0.83
Epoxyeicosatrienoic acids and heme oxygenase-1 interaction attenuates diabetes and metabolic syndrome complications. Prostaglandins Other Lipid Mediat (2011) 0.83
p53 status as effect modifier of the association between pre-treatment fasting glucose and breast cancer outcomes in non diabetic, HER2 positive patients treated with trastuzumab. Oncotarget (2014) 0.82
Update on the protective molecular pathways improving pancreatic beta-cell dysfunction. Mediators Inflamm (2013) 0.81
Hydrogen peroxide mediates hyperglycemia-induced invasive activity via ERK and p38 MAPK in human pancreatic cancer. Oncotarget (2015) 0.80
Padina arborescens extract protects high glucose-induced apoptosis in pancreatic β cells by reducing oxidative stress. Nutr Res Pract (2014) 0.79
Apollo-NADP(+): a spectrally tunable family of genetically encoded sensors for NADP(.). Nat Methods (2016) 0.78
Sesamin Ameliorates Advanced Glycation End Products-Induced Pancreatic β-Cell Dysfunction and Apoptosis. Nutrients (2015) 0.78
Hypoglycemic effects of glycosaminoglycan from Urechis unicinctus in diabetic mice. J Med Food (2014) 0.77
A prescribed Chinese herbal medicine improves glucose profile and ameliorates oxidative stress in Goto-Kakisaki rats fed with high fat diet. PLoS One (2013) 0.77
H2O2-Activated Mitochondrial Phospholipase iPLA2γ Prevents Lipotoxic Oxidative Stress in Synergy with UCP2, Amplifies Signaling via G-Protein-Coupled Receptor GPR40, and Regulates Insulin Secretion in Pancreatic β-Cells. Antioxid Redox Signal (2015) 0.76
Matrix metalloproteinase 2 contributes to pancreatic Beta cell injury induced by oxidative stress. PLoS One (2014) 0.76
Group VIB Phospholipase A(2) promotes proliferation of INS-1 insulinoma cells and attenuates lipid peroxidation and apoptosis induced by inflammatory cytokines and oxidant agents. Oxid Med Cell Longev (2012) 0.75
Antidiabetic effect of green rooibos (Aspalathus linearis) extract in cultured cells and type 2 diabetic model KK-A(y) mice. Cytotechnology (2014) 0.75
Risk of skin cancer in patients with diabetes mellitus: A nationwide retrospective cohort study in Taiwan. Medicine (Baltimore) (2016) 0.75
CXCL12 protects pancreatic β-cells from oxidative stress by a Nrf2-induced increase in catalase expression and activity. Proc Jpn Acad Ser B Phys Biol Sci (2016) 0.75
N-Acetyl-L-Cysteine inhibits the development of glucose intolerance and hepatic steatosis in diabetes-prone mice. Am J Transl Res (2016) 0.75
The antioxidant N-Acetylcysteine does not improve glucose tolerance or β-cell function in type 2 diabetes. J Diabetes Complications (2016) 0.75
Metabolic Stress and Compromised Identity of Pancreatic Beta Cells. Front Genet (2017) 0.75
Protective efficacy of folic acid and vitamin B12 against nicotine-induced toxicity in pancreatic islets of the rat. Interdiscip Toxicol (2015) 0.75
A global map of p53 transcription-factor binding sites in the human genome. Cell (2006) 20.65
ChIP-seq accurately predicts tissue-specific activity of enhancers. Nature (2009) 18.38
Metagenomic discovery of biomass-degrading genes and genomes from cow rumen. Science (2011) 6.93
Aldehyde dehydrogenase 1 is a marker for normal and malignant human colonic stem cells (SC) and tracks SC overpopulation during colon tumorigenesis. Cancer Res (2009) 6.43
Comparative full-length genome sequence analysis of 14 SARS coronavirus isolates and common mutations associated with putative origins of infection. Lancet (2003) 5.99
Whole-genome cartography of estrogen receptor alpha binding sites. PLoS Genet (2007) 5.85
ChIP-Seq identification of weakly conserved heart enhancers. Nat Genet (2010) 4.32
Rnnotator: an automated de novo transcriptome assembly pipeline from stranded RNA-Seq reads. BMC Genomics (2010) 2.62
Beclin1 controls the levels of p53 by regulating the deubiquitination activity of USP10 and USP13. Cell (2011) 2.58
A prospective, randomized study comparing outcomes and toxicities of intensity-modulated radiotherapy vs. conventional two-dimensional radiotherapy for the treatment of nasopharyngeal carcinoma. Radiother Oncol (2012) 2.54
Effects of propofol and ketamine as combined anesthesia for electroconvulsive therapy in patients with depressive disorder. J ECT (2012) 2.43
Direct-method SAD phasing of proteins enhanced by the use of intrinsic bimodal phase distributions in the subsequent phase-improvement process. Acta Crystallogr D Biol Crystallogr (2009) 2.28
Inactivation of specific β cell transcription factors in type 2 diabetes. J Clin Invest (2013) 2.18
Elevation of highly up-regulated in liver cancer (HULC) by hepatitis B virus X protein promotes hepatoma cell proliferation via down-regulating p18. J Biol Chem (2012) 2.16
Single-atom catalysis of CO oxidation using Pt1/FeOx. Nat Chem (2011) 1.98
Sulforaphane, a dietary component of broccoli/broccoli sprouts, inhibits breast cancer stem cells. Clin Cancer Res (2010) 1.96
The airborne metagenome in an indoor urban environment. PLoS One (2008) 1.81
Comparative study of four time series methods in forecasting typhoid fever incidence in China. PLoS One (2013) 1.78
Diabetes, glucose toxicity, and oxidative stress: A case of double jeopardy for the pancreatic islet beta cell. Free Radic Biol Med (2006) 1.74
Identification of ancient remains through genomic sequencing. Genome Res (2008) 1.72
Withaferin A targets heat shock protein 90 in pancreatic cancer cells. Biochem Pharmacol (2010) 1.69
Interval between palliative care referral and death among patients treated at a comprehensive cancer center. J Palliat Med (2005) 1.67
A novel systematic error compensation algorithm based on least squares support vector regression for star sensor image centroid estimation. Sensors (Basel) (2011) 1.64
Sensitization to gamma-irradiation-induced cell cycle arrest and apoptosis by the histone deacetylase inhibitor trichostatin A in non-small cell lung cancer (NSCLC) cells. Cancer Biol Ther (2009) 1.61
A potent and orally active antagonist (SM-406/AT-406) of multiple inhibitor of apoptosis proteins (IAPs) in clinical development for cancer treatment. J Med Chem (2011) 1.58
Model-based segmentation of medical imagery by matching distributions. IEEE Trans Med Imaging (2005) 1.57
SOX9 is expressed in normal prostate basal cells and regulates androgen receptor expression in prostate cancer cells. Cancer Res (2007) 1.57
Impurity effect on weak antilocalization in the topological insulator Bi2Te3. Phys Rev Lett (2011) 1.53
Nebulized versus subcutaneous morphine for patients with cancer dyspnea: a preliminary study. J Pain Symptom Manage (2005) 1.52
Thirty-day in-vivo performance of a wearable artificial pump-lung for ambulatory respiratory support. Ann Thorac Surg (2011) 1.52
Control of basal autophagy by calpain1 mediated cleavage of ATG5. Autophagy (2010) 1.51
Fatigue-induced damage in Zr-based bulk metallic glasses. Sci Rep (2013) 1.49
Anterior versus posterior approach for treatment of thoracolumbar burst fractures: a meta-analysis. Eur Spine J (2013) 1.49
A novel combined SLAM based on RBPF-SLAM and EIF-SLAM for mobile system sensing in a large scale environment. Sensors (Basel) (2011) 1.46
Patient-controlled methylphenidate for cancer fatigue: a double-blind, randomized, placebo-controlled trial. J Clin Oncol (2006) 1.45
Highly efficient extraction of serum peptides by ordered mesoporous carbon. Angew Chem Int Ed Engl (2011) 1.43
Active contours for tracking distributions. IEEE Trans Image Process (2004) 1.42
A novel small-molecule inhibitor of mcl-1 blocks pancreatic cancer growth in vitro and in vivo. Mol Cancer Ther (2013) 1.42
Regulation of alpha-cell function by the beta-cell during hypoglycemia in Wistar rats: the "switch-off" hypothesis. Diabetes (2004) 1.41
Quercetin induces protective autophagy in gastric cancer cells: involvement of Akt-mTOR- and hypoxia-induced factor 1α-mediated signaling. Autophagy (2011) 1.40
Zinc, not insulin, regulates the rat alpha-cell response to hypoglycemia in vivo. Diabetes (2007) 1.39
Genome-wide identification of regulatory DNA elements and protein-binding footprints using signatures of open chromatin in Arabidopsis. Plant Cell (2012) 1.38
Laparoscopic treatment for small intestinal bleeding: a report of 77 cases. J Laparoendosc Adv Surg Tech A (2010) 1.38
Access to palliative care among patients treated at a comprehensive cancer center. Oncologist (2012) 1.34
Regulation of the insulin gene by glucose and fatty acids. J Nutr (2006) 1.34
Androgen receptor remains critical for cell-cycle progression in androgen-independent CWR22 prostate cancer cells. Am J Pathol (2006) 1.33
Colonic crypt changes during adenoma development in familial adenomatous polyposis: immunohistochemical evidence for expansion of the crypt base cell population. Am J Pathol (2004) 1.33
Redox homeostasis: the linchpin in stem cell self-renewal and differentiation. Cell Death Dis (2013) 1.31
New developments in Hsp90 inhibitors as anti-cancer therapeutics: mechanisms, clinical perspective and more potential. Drug Resist Updat (2009) 1.27
One family cluster of avian influenza A(H7N9) virus infection in Shandong, China. BMC Infect Dis (2014) 1.26
Snail is critical for tumor growth and metastasis of ovarian carcinoma. Int J Cancer (2010) 1.26
Single-atom catalysts: a new frontier in heterogeneous catalysis. Acc Chem Res (2013) 1.23
Targeted agent use in cancer patients at the end of life. J Pain Symptom Manage (2012) 1.22
Mutational dynamics of the SARS coronavirus in cell culture and human populations isolated in 2003. BMC Infect Dis (2004) 1.21
Endoscopic management of benign tracheobronchial tumors. J Thorac Dis (2011) 1.21
Hypophosphorylation of residue Y1045 leads to defective downregulation of EGFRvIII. Cancer Biol Ther (2006) 1.20
Synergistic antipancreatic tumor effect by simultaneously targeting hypoxic cancer cells with HSP90 inhibitor and glycolysis inhibitor. Clin Cancer Res (2008) 1.19
microRNA-150 inhibits human CD133-positive liver cancer stem cells through negative regulation of the transcription factor c-Myb. Int J Oncol (2011) 1.18
Pancreatic islet beta-cell and oxidative stress: the importance of glutathione peroxidase. FEBS Lett (2007) 1.16
ATP-sensitive K+ channel mediates the zinc switch-off signal for glucagon response during glucose deprivation. Diabetes (2009) 1.16
FGFR4 promotes stroma-induced epithelial-to-mesenchymal transition in colorectal cancer. Cancer Res (2013) 1.16
Regulation of centrosome separation in yeast and vertebrates: common threads. Trends Cell Biol (2009) 1.15
Autophagy is a protective response to ethanol neurotoxicity. Autophagy (2012) 1.15
Prognostic significance of circulating tumor cells in non-small-cell lung cancer patients: a meta-analysis. PLoS One (2013) 1.15
Oxidative stress and apoptosis induced by nanosized titanium dioxide in PC12 cells. Toxicology (2009) 1.15
Predictors of access to palliative care services among patients who died at a Comprehensive Cancer Center. J Palliat Med (2007) 1.14
One-hit effects in cancer: altered proteome of morphologically normal colon crypts in familial adenomatous polyposis. Cancer Res (2008) 1.14
Regulation of alpha-cell function by the beta-cell in isolated human and rat islets deprived of glucose: the "switch-off" hypothesis. Diabetes (2004) 1.14
pH-sensitive nanoparticles for improving the oral bioavailability of cyclosporine A. Int J Pharm (2004) 1.14
A quantitative comparison of mechanical blood damage parameters in rotary ventricular assist devices: shear stress, exposure time and hemolysis index. J Biomech Eng (2012) 1.12
Proteomics identification of ITGB3 as a key regulator in reactive oxygen species-induced migration and invasion of colorectal cancer cells. Mol Cell Proteomics (2011) 1.12
Multiple tumor types may originate from bone marrow-derived cells. Neoplasia (2006) 1.10
Generation of long insert pairs using a Cre-LoxP Inverse PCR approach. PLoS One (2012) 1.09
Remarkable performance of Ir1/FeO(x) single-atom catalyst in water gas shift reaction. J Am Chem Soc (2013) 1.09
Intrahepatic glucose flux as a mechanism for defective intrahepatic islet alpha-cell response to hypoglycemia. Diabetes (2008) 1.08
Repair of massive stent-induced tracheoesophageal fistula. J Thorac Cardiovasc Surg (2009) 1.07
The Edmonton Symptom Assessment System as a screening tool for depression and anxiety. J Palliat Med (2006) 1.06
The antidiabetic drug metformin inhibits the proliferation of bladder cancer cells in vitro and in vivo. Int J Mol Sci (2013) 1.05
Computational characterization of flow and hemolytic performance of the UltraMag blood pump for circulatory support. Artif Organs (2010) 1.05
PRMT5 regulates Golgi apparatus structure through methylation of the golgin GM130. Cell Res (2010) 1.05
International collaboration to assess the risk of Guillain Barré Syndrome following Influenza A (H1N1) 2009 monovalent vaccines. Vaccine (2013) 1.05
Hepatitis B virus X protein upregulates oncogene Rab18 to result in the dysregulation of lipogenesis and proliferation of hepatoma cells. Carcinogenesis (2013) 1.04
Action potential changes associated with the inhibitory effects on voltage-gated sodium current of hippocampal CA1 neurons by silver nanoparticles. Toxicology (2009) 1.04
(-)-Epigallocatechin-3-gallate inhibits Hsp90 function by impairing Hsp90 association with cochaperones in pancreatic cancer cell line Mia Paca-2. Mol Pharm (2009) 1.03
Condensin I associates with structural and gene regulatory regions in vertebrate chromosomes. Nat Commun (2013) 1.02
Primitive human hematopoietic cells give rise to differentially specified daughter cells upon their initial cell division. Blood (2005) 1.02
Human infection with influenza virus A(H10N8) from live poultry markets, China, 2014. Emerg Infect Dis (2014) 1.02
Characterization of D-tagatose-3-epimerase from Rhodobacter sphaeroides that converts D-fructose into D-psicose. Biotechnol Lett (2009) 1.02
Influences of nanoparticle zinc oxide on acutely isolated rat hippocampal CA3 pyramidal neurons. Neurotoxicology (2008) 1.01
Upregulation of a disintegrin and metalloproteinase with thrombospondin motifs-7 by miR-29 repression mediates vascular smooth muscle calcification. Arterioscler Thromb Vasc Biol (2012) 1.01
Theoretical studies on vicinal-tetrazine compounds: furoxano-1,2,3,4-tetrazine-1,3,5-trioxide (FTTO-α) and furoxano-1,2,3,4-tetrazine-1,3,7-trioxide (FTTO-β). J Mol Model (2014) 1.01
A natural small molecule harmine inhibits angiogenesis and suppresses tumour growth through activation of p53 in endothelial cells. PLoS One (2012) 1.00
Involvement of endoplasmic reticulum stress in myocardial apoptosis of streptozocin-induced diabetic rats. J Clin Biochem Nutr (2007) 0.99
Structurally designed synthesis of mechanically stable poly(benzoxazine-co-resol)-based porous carbon monoliths and their application as high-performance CO2 capture sorbents. J Am Chem Soc (2011) 0.99
Tibial lengthening over an intramedullary nail in patients with short stature or leg-length discrepancy: a comparative study. Int Orthop (2011) 0.99
Field test of wavelength-saving quantum key distribution network. Opt Lett (2010) 0.99
Interactive effects of nitrogen and phosphorus on soil microbial communities in a tropical forest. PLoS One (2013) 0.99
Correlation of intestinal microbiota with overweight and obesity in Kazakh school children. BMC Microbiol (2012) 0.99
Venous and arterial flow quantification are equally accurate and precise with parallel imaging compressed sensing 4D phase contrast MRI. J Magn Reson Imaging (2012) 0.98