Published in Environ Sci Technol on July 15, 2007
The TEAD/TEF family of transcription factor Scalloped mediates Hippo signaling in organ size control. Dev Cell (2008) 4.90
Mammalian Mst1 and Mst2 kinases play essential roles in organ size control and tumor suppression. Proc Natl Acad Sci U S A (2010) 4.17
The Drosophila Ste20 family kinase dMST functions as a tumor suppressor by restricting cell proliferation and promoting apoptosis. Genes Dev (2003) 3.53
Tissue damage-induced intestinal stem cell division in Drosophila. Cell Stem Cell (2009) 3.43
Role for Slimb in the degradation of Drosophila Period protein phosphorylated by Doubletime. Nature (2002) 2.99
Hedgehog-regulated Costal2-kinase complexes control phosphorylation and proteolytic processing of Cubitus interruptus. Dev Cell (2005) 2.50
Small-molecule inhibitors reveal multiple strategies for Hedgehog pathway blockade. Proc Natl Acad Sci U S A (2009) 2.41
Hedgehog signalling activity of Smoothened requires phosphorylation by protein kinase A and casein kinase I. Nature (2004) 2.39
Shaggy/GSK3 antagonizes Hedgehog signalling by regulating Cubitus interruptus. Nature (2002) 2.26
Hedgehog regulates smoothened activity by inducing a conformational switch. Nature (2007) 2.23
Hippo signaling regulates Drosophila intestine stem cell proliferation through multiple pathways. Proc Natl Acad Sci U S A (2010) 2.16
A hedgehog-induced BTB protein modulates hedgehog signaling by degrading Ci/Gli transcription factor. Dev Cell (2006) 2.13
Phosphorylation by double-time/CKIepsilon and CKIalpha targets cubitus interruptus for Slimb/beta-TRCP-mediated proteolytic processing. Dev Cell (2005) 1.62
Hippo signaling regulates Yorkie nuclear localization and activity through 14-3-3 dependent and independent mechanisms. Dev Biol (2009) 1.54
Drosophila WntD is a target and an inhibitor of the Dorsal/Twist/Snail network in the gastrulating embryo. Development (2005) 1.51
Multiple Ser/Thr-rich degrons mediate the degradation of Ci/Gli by the Cul3-HIB/SPOP E3 ubiquitin ligase. Proc Natl Acad Sci U S A (2009) 1.47
Smoothened transduces Hedgehog signal by physically interacting with Costal2/Fused complex through its C-terminal tail. Genes Dev (2003) 1.44
Oxidation of sulfoxides and arsenic(III) in corrosion of nanoscale zero valent iron by oxygen: evidence against ferryl ions (Fe(IV)) as active intermediates in Fenton reaction. Environ Sci Technol (2010) 1.42
Sonic Hedgehog dependent phosphorylation by CK1α and GRK2 is required for ciliary accumulation and activation of smoothened. PLoS Biol (2011) 1.36
Fused-Costal2 protein complex regulates Hedgehog-induced Smo phosphorylation and cell-surface accumulation. Genes Dev (2007) 1.24
Plexins are GTPase-activating proteins for Rap and are activated by induced dimerization. Sci Signal (2012) 1.23
Hippo signaling pathway and organ size control. Fly (Austin) (2009) 1.21
G protein-coupled receptor kinase 2 promotes high-level Hedgehog signaling by regulating the active state of Smo through kinase-dependent and kinase-independent mechanisms in Drosophila. Genes Dev (2010) 1.17
The cell adhesion molecule echinoid functions as a tumor suppressor and upstream regulator of the Hippo signaling pathway. Dev Cell (2012) 1.16
Vacuolar H+-ATPase binding to microfilaments: regulation in response to phosphatidylinositol 3-kinase activity and detailed characterization of the actin-binding site in subunit B. J Biol Chem (2003) 1.16
Tuberous sclerosis complex and Myc coordinate the growth and division of Drosophila intestinal stem cells. J Cell Biol (2011) 1.13
A novel mutation in the major intrinsic protein (MIP) associated with autosomal dominant congenital cataracts in a Chinese family. Mol Vis (2010) 1.13
Cytotoxicity evaluation of endosequence root repair material. Oral Surg Oral Med Oral Pathol Oral Radiol Endod (2010) 1.12
Smoothened transduces Hedgehog signal by forming a complex with Evc/Evc2. Cell Res (2012) 1.11
Hedgehog-regulated ubiquitination controls smoothened trafficking and cell surface expression in Drosophila. PLoS Biol (2012) 1.09
Novel FBN1 mutations associated with predominant ectopia lentis and marfanoid habitus in Chinese patients. Mol Vis (2007) 1.09
Casein kinase 2 promotes Hedgehog signaling by regulating both smoothened and Cubitus interruptus. J Biol Chem (2010) 1.07
Actin-related protein 2/3 complex is required for actin ring formation. J Bone Miner Res (2003) 1.07
Decoding the phosphorylation code in Hedgehog signal transduction. Cell Res (2013) 1.06
The confounding effects of dissolved humic acid on the oxidation of simple substituted phenols by permanganate: comment on "reinvestigation of the role of humic acid in the oxidation of phenols by permanganate". Environ Sci Technol (2014) 1.06
Regulation of wingless signaling by the CKI family in Drosophila limb development. Dev Biol (2006) 1.04
Global DNA hypomethylation is associated with NTD-affected pregnancy: A case-control study. Birth Defects Res A Clin Mol Teratol (2010) 1.02
Blockade of costimulation between T cells and antigen-presenting cells: an approach to suppress murine Graves' disease induced using thyrotropin receptor-expressing adenovirus. Thyroid (2006) 1.02
Multiple Cos2/Ci interactions regulate Ci subcellular localization through microtubule dependent and independent mechanisms. Dev Biol (2004) 1.01
Emdogain promotes osteoblast proliferation and differentiation and stimulates osteoprotegerin expression. Oral Surg Oral Med Oral Pathol Oral Radiol Endod (2004) 0.98
The Hedgehog-induced Smoothened conformational switch assembles a signaling complex that activates Fused by promoting its dimerization and phosphorylation. Development (2011) 0.98
Porphyromonas gingivalis lipids inhibit osteoblastic differentiation and function. Infect Immun (2010) 0.97
A nonsense mutation in CRYGC associated with autosomal dominant congenital nuclear cataract in a Chinese family. Mol Vis (2008) 0.96
Amperometric sensor based on ferrocene-modified multiwalled carbon nanotube nanocomposites as electron mediator for the determination of glucose. Anal Biochem (2008) 0.96
Intestinal epithelium-derived BMP controls stem cell self-renewal in Drosophila adult midgut. Elife (2014) 0.96
Altered expression of long non-coding RNAs during genotoxic stress-induced cell death in human glioma cells. J Neurooncol (2015) 0.95
Effect of selected accelerants on setting time and biocompatibility of mineral trioxide aggregate (MTA). Oral Surg Oral Med Oral Pathol Oral Radiol Endod (2011) 0.95
MicroRNA-21 and risk of severe acute kidney injury and poor outcomes after adult cardiac surgery. PLoS One (2013) 0.94
Structural insight into the mutual recognition and regulation between Suppressor of Fused and Gli/Ci. Nat Commun (2013) 0.94
Identification of domains responsible for ubiquitin-dependent degradation of dMyc by glycogen synthase kinase 3beta and casein kinase 1 kinases. Mol Cell Biol (2009) 0.94
Using immunoprecipitation to study protein-protein interactions in the Hedgehog-signaling pathway. Methods Mol Biol (2007) 0.94
Modes of failure of ProTaper nickel-titanium rotary instruments after clinical use. J Endod (2007) 0.93
Imaging port wine stains by fiber optical coherence tomography. J Biomed Opt (2010) 0.93
Actin binding activity of subunit B of vacuolar H+-ATPase is involved in its targeting to ruffled membranes of osteoclasts. J Bone Miner Res (2006) 0.93
Molecular genetic analysis of the glycosyltransferase Fringe in Drosophila. Proc Natl Acad Sci U S A (2003) 0.92
Selective Modulation of Paracortical Dendritic Cells and T-Lymphocytes in Breast Cancer Sentinel Lymph Nodes. Breast J (2000) 0.92
Par-1 regulates tissue growth by influencing hippo phosphorylation status and hippo-salvador association. PLoS Biol (2013) 0.92
Converse conformational control of smoothened activity by structurally related small molecules. J Biol Chem (2009) 0.90
Cytotoxicity evaluation of Gutta Flow and Endo Sequence BC sealers. Oral Surg Oral Med Oral Pathol Oral Radiol Endod (2011) 0.90
Suppression of Hedgehog signaling by Cul3 ligases in proliferation control of retinal precursors. Dev Biol (2007) 0.90
Intra-family phenotypic heterogeneity of 16p11.2 deletion carriers in a three-generation Chinese family. Am J Med Genet B Neuropsychiatr Genet (2010) 0.90
Role of dopamine D2 receptors in ischemia/reperfusion induced apoptosis of cultured neonatal rat cardiomyocytes. J Biomed Sci (2011) 0.89
Dimerization and cytoplasmic localization regulate Hippo kinase signaling activity in organ size control. J Biol Chem (2012) 0.89
[Relationship between ephemeral plants distribution and soil moisture on longitudinal dune surface in Gurbantonggut desert]. Ying Yong Sheng Tai Xue Bao (2004) 0.88
The calcium-sensing receptor mediates hypoxia-induced proliferation of rat pulmonary artery smooth muscle cells through MEK1/ERK1,2 and PI3K pathways. Basic Clin Pharmacol Toxicol (2010) 0.88
Detection of copy number variants reveals association of cilia genes with neural tube defects. PLoS One (2013) 0.87
Transducing the Hedgehog signal across the plasma membrane. Fly (Austin) (2007) 0.87
Apical infection spreading to adjacent teeth: a case report. Oral Surg Oral Med Oral Pathol Oral Radiol Endod (2011) 0.87
Fem1b promotes ubiquitylation and suppresses transcriptional activity of Gli1. Biochem Biophys Res Commun (2013) 0.87
Altered methylation of IGF2 DMR0 is associated with neural tube defects. Mol Cell Biochem (2013) 0.86
Drosophila Myc integrates multiple signaling pathways to regulate intestinal stem cell proliferation during midgut regeneration. Cell Res (2013) 0.86
Subvastus versus medial parapatellar approach in total knee arthroplasty: meta-analysis. Orthopedics (2012) 0.86
Cytotoxicity evaluation of Activ GP and Resilon cones in vitro. Oral Surg Oral Med Oral Pathol Oral Radiol Endod (2008) 0.86
Dual roles of Hh signaling in the regulation of somatic stem cell self-renewal and germline stem cell maintenance in Drosophila testis. Cell Res (2013) 0.86
A micro-computed tomography study of canal configuration of multiple-canalled mesiobuccal root of maxillary first molar. Clin Oral Investig (2012) 0.86
Thyroglobulin-thyroperoxidase autoantibodies are polyreactive, not bispecific: analysis using human monoclonal autoantibodies. J Clin Endocrinol Metab (2003) 0.86
Effects of basic fibroblast growth factor on osteoclasts and osteoclast-like cells. Biochem Biophys Res Commun (2004) 0.84
Directed mutagenesis in region 713-720 of human thyroperoxidase assigns 713KFPED717 residues as being involved in the B domain of the discontinuous immunodominant region recognized by human autoantibodies. J Biol Chem (2004) 0.84
Cytotoxicity evaluation of Activ GP and Resilon sealers in vitro. Oral Surg Oral Med Oral Pathol Oral Radiol Endod (2009) 0.84
Evaluation of cytotoxicity of MTA employing various additives. Oral Surg Oral Med Oral Pathol Oral Radiol Endod (2009) 0.84
Circulation times of prostate cancer and hepatocellular carcinoma cells by in vivo flow cytometry. Cytometry A (2011) 0.83
The functional expression of extracellular calcium-sensing receptor in rat pulmonary artery smooth muscle cells. J Biomed Sci (2011) 0.83
A novel GJA3 mutation associated with congenital nuclear pulverulent and posterior polar cataract in a Chinese family. Hum Mutat (2011) 0.83
Involvement of calcium-sensing receptor in oxLDL-induced MMP-2 production in vascular smooth muscle cells via PI3K/Akt pathway. Mol Cell Biochem (2011) 0.83
Gamma-secretase-regulated proteolysis of the Notch receptor by mitochondrial intermediate peptidase. J Biol Chem (2011) 0.83
[Neuroanatomical characteristics of acupoint "Chengshan" (BL 57) in the rat: a cholera toxin subunit B conjugated with Alexa Fluor 488 method study]. Zhen Ci Yan Jiu (2010) 0.82
Interactions between vacuolar H+-ATPases and microfilaments in osteoclasts. J Bioenerg Biomembr (2005) 0.82
Contribution of D4-F to ABCA1 expression and cholesterol efflux in THP-1 macrophage-derived foam cells. J Cardiovasc Pharmacol (2010) 0.82
Ocular leech infestation initially misdiagnosed as conjunctival pigmented nevus. Int J Ophthalmol (2013) 0.81
Phase analysis by gated F-18 FDG PET/CT for left ventricular dyssynchrony assessment: a comparison with gated Tc-99m sestamibi SPECT. Ann Nucl Med (2013) 0.81
Ibrolipim increases ABCA1/G1 expression by the LXRα signaling pathway in THP-1 macrophage-derived foam cells. Acta Pharmacol Sin (2010) 0.81
Dynamic changes of ocular biometric parameters: a modified form-deprivation myopia model of young guinea pigs. Int J Ophthalmol (2011) 0.81
Human autoantibodies modulate the T cell epitope repertoire but fail to unmask a pathogenic cryptic epitope. J Immunol (2005) 0.81
Production of transgenic dairy goat expressing human α-lactalbumin by somatic cell nuclear transfer. Transgenic Res (2014) 0.80
A rapid nondestructive method for root dentin moisture measurements: in vitro pilot study. Oral Surg Oral Med Oral Pathol Oral Radiol Endod (2009) 0.80
Altered methylation of the DNA repair gene MGMT is associated with neural tube defects. J Mol Neurosci (2011) 0.80
The efficacy of steroid injection in total knee or hip arthroplasty. Knee Surg Sports Traumatol Arthrosc (2014) 0.79
Establishment of an immortalized GABAergic neuronal progenitor cell line from embryonic ventral mesencephalon in the rat. Brain Res (2008) 0.79