Published in Dev Cell on January 25, 2012
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Polarity-dependent distribution of angiomotin localizes Hippo signaling in preimplantation embryos. Curr Biol (2013) 1.86
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Growth control by committee: intercellular junctions, cell polarity, and the cytoskeleton regulate Hippo signaling. Dev Cell (2012) 1.26
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The Hippo signalling pathway maintains quiescence in Drosophila neural stem cells. Nat Commun (2016) 0.88
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The palmitoyltransferase Approximated promotes growth via the Hippo pathway by palmitoylation of Fat. J Cell Biol (2016) 0.84
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SCF(Slmb) E3 ligase-mediated degradation of Expanded is inhibited by the Hippo pathway in Drosophila. Cell Res (2014) 0.82
Localization of Hippo signalling complexes and Warts activation in vivo. Nat Commun (2015) 0.81
A Drosophila RNAi library modulates Hippo pathway-dependent tissue growth. Nat Commun (2016) 0.79
The Hippo signaling pathway provides novel anti-cancer drug targets. Oncotarget (2016) 0.79
Overlapping functions of the MAP4K family kinases Hppy and Msn in Hippo signaling. Cell Discov (2015) 0.77
Bazooka/PAR3 is dispensable for polarity in Drosophila follicular epithelial cells. Biol Open (2015) 0.77
Hippo Stabilises Its Adaptor Salvador by Antagonising the HECT Ubiquitin Ligase Herc4. PLoS One (2015) 0.76
Drosophila casein kinase 2 (CK2) promotes warts protein to suppress Yorkie protein activity for growth control. J Biol Chem (2014) 0.76
BMP9 Crosstalk with the Hippo Pathway Regulates Endothelial Cell Matricellular and Chemokine Responses. PLoS One (2015) 0.75
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Connections between cadherin-catenin proteins, spindle misorientation, and cancer. Tissue Barriers (2015) 0.75
Kibra and Merlin Activate the Hippo Pathway Spatially Distinct from and Independent of Expanded. Dev Cell (2017) 0.75
Drosophila ste-20 family protein kinase, hippo, modulates fat cell proliferation. PLoS One (2013) 0.75
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The Hippo signaling pathway coordinately regulates cell proliferation and apoptosis by inactivating Yorkie, the Drosophila Homolog of YAP. Cell (2005) 10.61
The hippo signaling pathway in development and cancer. Dev Cell (2010) 10.54
hippo encodes a Ste-20 family protein kinase that restricts cell proliferation and promotes apoptosis in conjunction with salvador and warts. Cell (2003) 7.43
salvador Promotes both cell cycle exit and apoptosis in Drosophila and is mutated in human cancer cell lines. Cell (2002) 7.15
The tumour-suppressor genes NF2/Merlin and Expanded act through Hippo signalling to regulate cell proliferation and apoptosis. Nat Cell Biol (2005) 6.74
The Drosophila Mst ortholog, hippo, restricts growth and cell proliferation and promotes apoptosis. Cell (2003) 6.48
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The TEAD/TEF family protein Scalloped mediates transcriptional output of the Hippo growth-regulatory pathway. Dev Cell (2008) 5.58
Hippo promotes proliferation arrest and apoptosis in the Salvador/Warts pathway. Nat Cell Biol (2003) 5.50
The Drosophila tumor suppressor gene warts encodes a homolog of human myotonic dystrophy kinase and is required for the control of cell shape and proliferation. Genes Dev (1995) 5.27
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Identifying tumor suppressors in genetic mosaics: the Drosophila lats gene encodes a putative protein kinase. Development (1995) 5.18
Control of cell proliferation and apoptosis by mob as tumor suppressor, mats. Cell (2005) 5.10
Delineation of a Fat tumor suppressor pathway. Nat Genet (2006) 5.06
The TEAD/TEF family of transcription factor Scalloped mediates Hippo signaling in organ size control. Dev Cell (2008) 4.90
The Salvador partner Hippo promotes apoptosis and cell-cycle exit in Drosophila. Nat Cell Biol (2003) 4.84
The fat cadherin acts through the hippo tumor-suppressor pathway to regulate tissue size. Curr Biol (2006) 3.90
The tumor-suppressor gene fat controls tissue growth upstream of expanded in the hippo signaling pathway. Curr Biol (2006) 3.83
The Hippo pathway regulates the bantam microRNA to control cell proliferation and apoptosis in Drosophila. Cell (2006) 3.81
Fat cadherin modulates organ size in Drosophila via the Salvador/Warts/Hippo signaling pathway. Curr Biol (2006) 3.72
The Drosophila Ste20 family kinase dMST functions as a tumor suppressor by restricting cell proliferation and promoting apoptosis. Genes Dev (2003) 3.53
In vivo regulation of Yorkie phosphorylation and localization. Development (2008) 3.51
SCALLOPED interacts with YORKIE, the nuclear effector of the hippo tumor-suppressor pathway in Drosophila. Curr Biol (2008) 3.39
Crumbs regulates Salvador/Warts/Hippo signaling in Drosophila via the FERM-domain protein Expanded. Curr Biol (2010) 3.08
Lgl, aPKC, and Crumbs regulate the Salvador/Warts/Hippo pathway through two distinct mechanisms. Curr Biol (2010) 2.97
Kibra functions as a tumor suppressor protein that regulates Hippo signaling in conjunction with Merlin and Expanded. Dev Cell (2010) 2.96
Shar-pei mediates cell proliferation arrest during imaginal disc growth in Drosophila. Development (2002) 2.82
Kibra is a regulator of the Salvador/Warts/Hippo signaling network. Dev Cell (2010) 2.73
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The FERM-domain protein Expanded regulates Hippo pathway activity via direct interactions with the transcriptional activator Yorkie. Dev Cell (2009) 2.53
Mob as tumor suppressor is activated by Hippo kinase for growth inhibition in Drosophila. EMBO J (2007) 2.46
The apical transmembrane protein Crumbs functions as a tumor suppressor that regulates Hippo signaling by binding to Expanded. Proc Natl Acad Sci U S A (2010) 2.43
TSLC1 is a tumor-suppressor gene in human non-small-cell lung cancer. Nat Genet (2001) 2.37
The tumor suppressors Merlin and Expanded function cooperatively to modulate receptor endocytosis and signaling. Curr Biol (2006) 2.37
The WW domain protein Kibra acts upstream of Hippo in Drosophila. Dev Cell (2010) 2.34
Separating the adhesive and signaling functions of the Fat and Dachsous protocadherins. Development (2006) 2.30
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The apical-basal cell polarity determinant Crumbs regulates Hippo signaling in Drosophila. Proc Natl Acad Sci U S A (2010) 2.19
The Drosophila tumor suppressors Expanded and Merlin differentially regulate cell cycle exit, apoptosis, and Wingless signaling. Dev Biol (2006) 1.85
Salvador-warts-hippo signaling promotes Drosophila posterior follicle cell maturation downstream of notch. Curr Biol (2007) 1.75
Echinoid is a component of adherens junctions that cooperates with DE-Cadherin to mediate cell adhesion. Dev Cell (2005) 1.73
Direct association of TSLC1 and DAL-1, two distinct tumor suppressor proteins in lung cancer. Cancer Res (2002) 1.59
The salvador-warts-hippo pathway is required for epithelial proliferation and axis specification in Drosophila. Curr Biol (2007) 1.59
Hippo signaling regulates Yorkie nuclear localization and activity through 14-3-3 dependent and independent mechanisms. Dev Biol (2009) 1.54
The hippo pathway promotes Notch signaling in regulation of cell differentiation, proliferation, and oocyte polarity. PLoS One (2008) 1.53
Involvement of a cell adhesion molecule, TSLC1/IGSF4, in human oncogenesis. Cancer Sci (2005) 1.51
Multiple Ser/Thr-rich degrons mediate the degradation of Ci/Gli by the Cul3-HIB/SPOP E3 ubiquitin ligase. Proc Natl Acad Sci U S A (2009) 1.47
The Hippo pathway and apico-basal cell polarity. Biochem J (2011) 1.45
Human NDR kinases are rapidly activated by MOB proteins through recruitment to the plasma membrane and phosphorylation. Mol Cell Biol (2005) 1.43
The tumor suppressor protein TSLC1 is involved in cell-cell adhesion. J Biol Chem (2002) 1.33
Echinoid is essential for regulation of Egfr signaling and R8 formation during Drosophila eye development. Development (2003) 1.25
Association of a lung tumor suppressor TSLC1 with MPP3, a human homologue of Drosophila tumor suppressor Dlg. Oncogene (2003) 1.25
Hippo signaling pathway and organ size control. Fly (Austin) (2009) 1.21
Neuroglian activates Echinoid to antagonize the Drosophila EGF receptor signaling pathway. Development (2003) 1.05
The cell adhesion molecule Echinoid defines a new pathway that antagonizes the Drosophila EGF receptor signaling pathway. Development (2001) 1.00
The cell adhesion molecules Echinoid and Friend of Echinoid coordinate cell adhesion and cell signaling to regulate the fidelity of ommatidial rotation in the Drosophila eye. Development (2009) 0.82
The TEAD/TEF family of transcription factor Scalloped mediates Hippo signaling in organ size control. Dev Cell (2008) 4.90
Mammalian Mst1 and Mst2 kinases play essential roles in organ size control and tumor suppression. Proc Natl Acad Sci U S A (2010) 4.17
The Drosophila Ste20 family kinase dMST functions as a tumor suppressor by restricting cell proliferation and promoting apoptosis. Genes Dev (2003) 3.53
Tissue damage-induced intestinal stem cell division in Drosophila. Cell Stem Cell (2009) 3.43
Role for Slimb in the degradation of Drosophila Period protein phosphorylated by Doubletime. Nature (2002) 2.99
Hedgehog-regulated Costal2-kinase complexes control phosphorylation and proteolytic processing of Cubitus interruptus. Dev Cell (2005) 2.50
Small-molecule inhibitors reveal multiple strategies for Hedgehog pathway blockade. Proc Natl Acad Sci U S A (2009) 2.41
Hedgehog signalling activity of Smoothened requires phosphorylation by protein kinase A and casein kinase I. Nature (2004) 2.39
Shaggy/GSK3 antagonizes Hedgehog signalling by regulating Cubitus interruptus. Nature (2002) 2.26
Hedgehog regulates smoothened activity by inducing a conformational switch. Nature (2007) 2.23
Hippo signaling regulates Drosophila intestine stem cell proliferation through multiple pathways. Proc Natl Acad Sci U S A (2010) 2.16
A hedgehog-induced BTB protein modulates hedgehog signaling by degrading Ci/Gli transcription factor. Dev Cell (2006) 2.13
Phosphorylation by double-time/CKIepsilon and CKIalpha targets cubitus interruptus for Slimb/beta-TRCP-mediated proteolytic processing. Dev Cell (2005) 1.62
Hippo signaling regulates Yorkie nuclear localization and activity through 14-3-3 dependent and independent mechanisms. Dev Biol (2009) 1.54
Drosophila WntD is a target and an inhibitor of the Dorsal/Twist/Snail network in the gastrulating embryo. Development (2005) 1.51
Multiple Ser/Thr-rich degrons mediate the degradation of Ci/Gli by the Cul3-HIB/SPOP E3 ubiquitin ligase. Proc Natl Acad Sci U S A (2009) 1.47
Smoothened transduces Hedgehog signal by physically interacting with Costal2/Fused complex through its C-terminal tail. Genes Dev (2003) 1.44
Oxidation of sulfoxides and arsenic(III) in corrosion of nanoscale zero valent iron by oxygen: evidence against ferryl ions (Fe(IV)) as active intermediates in Fenton reaction. Environ Sci Technol (2010) 1.42
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Fused-Costal2 protein complex regulates Hedgehog-induced Smo phosphorylation and cell-surface accumulation. Genes Dev (2007) 1.24
Plexins are GTPase-activating proteins for Rap and are activated by induced dimerization. Sci Signal (2012) 1.23
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G protein-coupled receptor kinase 2 promotes high-level Hedgehog signaling by regulating the active state of Smo through kinase-dependent and kinase-independent mechanisms in Drosophila. Genes Dev (2010) 1.17
Vacuolar H+-ATPase binding to microfilaments: regulation in response to phosphatidylinositol 3-kinase activity and detailed characterization of the actin-binding site in subunit B. J Biol Chem (2003) 1.16
Tuberous sclerosis complex and Myc coordinate the growth and division of Drosophila intestinal stem cells. J Cell Biol (2011) 1.13
A novel mutation in the major intrinsic protein (MIP) associated with autosomal dominant congenital cataracts in a Chinese family. Mol Vis (2010) 1.13
Cytotoxicity evaluation of endosequence root repair material. Oral Surg Oral Med Oral Pathol Oral Radiol Endod (2010) 1.12
Smoothened transduces Hedgehog signal by forming a complex with Evc/Evc2. Cell Res (2012) 1.11
Hedgehog-regulated ubiquitination controls smoothened trafficking and cell surface expression in Drosophila. PLoS Biol (2012) 1.09
Novel FBN1 mutations associated with predominant ectopia lentis and marfanoid habitus in Chinese patients. Mol Vis (2007) 1.09
Casein kinase 2 promotes Hedgehog signaling by regulating both smoothened and Cubitus interruptus. J Biol Chem (2010) 1.07
Actin-related protein 2/3 complex is required for actin ring formation. J Bone Miner Res (2003) 1.07
Decoding the phosphorylation code in Hedgehog signal transduction. Cell Res (2013) 1.06
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The Hedgehog-induced Smoothened conformational switch assembles a signaling complex that activates Fused by promoting its dimerization and phosphorylation. Development (2011) 0.98
Porphyromonas gingivalis lipids inhibit osteoblastic differentiation and function. Infect Immun (2010) 0.97
A nonsense mutation in CRYGC associated with autosomal dominant congenital nuclear cataract in a Chinese family. Mol Vis (2008) 0.96
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Identification of domains responsible for ubiquitin-dependent degradation of dMyc by glycogen synthase kinase 3beta and casein kinase 1 kinases. Mol Cell Biol (2009) 0.94
Structural insight into the mutual recognition and regulation between Suppressor of Fused and Gli/Ci. Nat Commun (2013) 0.94
Using immunoprecipitation to study protein-protein interactions in the Hedgehog-signaling pathway. Methods Mol Biol (2007) 0.94
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Actin binding activity of subunit B of vacuolar H+-ATPase is involved in its targeting to ruffled membranes of osteoclasts. J Bone Miner Res (2006) 0.93
Par-1 regulates tissue growth by influencing hippo phosphorylation status and hippo-salvador association. PLoS Biol (2013) 0.92
Molecular genetic analysis of the glycosyltransferase Fringe in Drosophila. Proc Natl Acad Sci U S A (2003) 0.92
Suppression of Hedgehog signaling by Cul3 ligases in proliferation control of retinal precursors. Dev Biol (2007) 0.90
Converse conformational control of smoothened activity by structurally related small molecules. J Biol Chem (2009) 0.90
Cytotoxicity evaluation of Gutta Flow and Endo Sequence BC sealers. Oral Surg Oral Med Oral Pathol Oral Radiol Endod (2011) 0.90
Dimerization and cytoplasmic localization regulate Hippo kinase signaling activity in organ size control. J Biol Chem (2012) 0.89
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Drosophila Myc integrates multiple signaling pathways to regulate intestinal stem cell proliferation during midgut regeneration. Cell Res (2013) 0.86
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Direct contact between enamel matrix derivative (EMD) and osteoblasts is not required for EMD-induced cell proliferation. Oral Surg Oral Med Oral Pathol Oral Radiol Endod (2004) 0.76
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SCYL1BP1 has tumor-suppressive functions in human lung squamous carcinoma cells by regulating degradation of MDM2. Asian Pac J Cancer Prev (2014) 0.76
New insight into the oxidation of arsenite by the reaction of zerovalent iron and oxygen. Comment on "pH dependence of Fenton reagent generation and As(III) oxidation and removal by corrosion of zero valent iron in aerated water". Environ Sci Technol (2009) 0.75
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trans-Tris(4-bromo-phen-yl)dichlorido-antimony(V). Acta Crystallogr Sect E Struct Rep Online (2012) 0.75
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