Published in Science on October 26, 1962
Streptococcal M protein: alpha-helical coiled-coil structure and arrangement on the cell surface. Proc Natl Acad Sci U S A (1981) 5.56
Use of hospital services by homeless families in an inner London health district. BMJ (1989) 4.71
Randomised placebo-controlled trial of ritonavir in advanced HIV-1 disease. The Advanced HIV Disease Ritonavir Study Group. Lancet (1998) 4.54
American Cancer Society guidelines for the early detection of cancer: update of early detection guidelines for prostate, colorectal, and endometrial cancers. Also: update 2001--testing for early lung cancer detection. CA Cancer J Clin (2001) 4.41
The calcium and magnesium binding sites on troponin and their role in the regulation of myofibrillar adenosine triphosphatase. J Biol Chem (1975) 4.37
Cyclopiazonic acid is a specific inhibitor of the Ca2+-ATPase of sarcoplasmic reticulum. J Biol Chem (1989) 4.15
Reconstitution of troponin activity from three protein components. J Biol Chem (1971) 3.13
Three conformational states of scallop myosin S1. Proc Natl Acad Sci U S A (2000) 3.06
Atomic structure of scallop myosin subfragment S1 complexed with MgADP: a novel conformation of the myosin head. Cell (1999) 2.99
Submillisecond rotational dynamics of spin-labeled myosin heads in myofibrils. Biophys J (1980) 2.88
Structure of the regulatory domain of scallop myosin at 2.8 A resolution. Nature (1994) 2.78
A tropomyosin-like protein from human platelets. J Mol Biol (1972) 2.65
Tropomyosin crystal structure and muscle regulation. J Mol Biol (1986) 2.65
Zero-length crosslinking procedure with the use of active esters. Anal Biochem (1990) 2.63
Interim report on pandemic H1N1 influenza virus infections in South Africa, April to October 2009: epidemiology and factors associated with fatal cases. Euro Surveill (2009) 2.47
Cooperative effects of INK4a and ras in melanoma susceptibility in vivo. Genes Dev (1997) 2.47
Structure of the regulatory domain of scallop myosin at 2 A resolution: implications for regulation. Structure (1996) 2.45
Paramyosin and the filaments of molluscan "catch" muscles. II. Native filaments: isolation and characterization. J Mol Biol (1971) 2.42
Heptad breaks in alpha-helical coiled coils: stutters and stammers. Proteins (1996) 2.30
Sarcoplasmic reticulum. IV. Solubilization of microsomal adenosine triphosphatase. J Biol Chem (1968) 2.27
The binding of arsenazo III to cell components. Biochim Biophys Acta (1980) 2.26
Crystal structure and molecular interactions of tropomyosin. Nature (1979) 2.16
Deciphering the design of the tropomyosin molecule. Proc Natl Acad Sci U S A (2001) 2.14
Laparoscopic live donor nephrectomy: the recipient. Transplantation (2000) 2.11
Photoaffinity labelling with an ATP analog of the N-terminal peptide of myosin. Biochem Biophys Res Commun (1979) 2.08
Classes and subclasses of rat immunoglobulins: interaction with the complement system and with staphylococcal protein A. Immunochemistry (1978) 2.06
Sarcoplasmic reticulum. IX. The permeability of sarcoplasmic reticulum membranes. J Gen Physiol (1970) 2.03
Rotational dynamics of spin-labeled F-actin in the sub-millisecond time range. J Mol Biol (1979) 1.99
Sarcoplasmic reticulum. 3. The role of phospholipids in the adenosine triphosphatase activity and Ca++ transport. J Biol Chem (1968) 1.97
Leishmaniasis acquired in Belgium. Lancet (1991) 1.93
Thin filament proteins and thin filament-linked regulation of vertebrate muscle contraction. CRC Crit Rev Biochem (1984) 1.91
Light chains of myosins from white, red, and cardiac muscles. Proc Natl Acad Sci U S A (1971) 1.91
Myosin alkali light chain and heavy chain variations correlate with altered shortening velocity of isolated skeletal muscle fibers. J Biol Chem (1988) 1.90
The substructure of heavy meromyosin. The effect of Ca2+ and Mg2+ on the tryptic fragmentation of heavy meromyosin. J Biol Chem (1975) 1.90
Expression profiling of renal epithelial neoplasms: a method for tumor classification and discovery of diagnostic molecular markers. Am J Pathol (2001) 1.89
X-ray diffraction from microtubules. J Mol Biol (1971) 1.84
Crystallographic findings on the internally uncoupled and near-rigor states of myosin: further insights into the mechanics of the motor. Proc Natl Acad Sci U S A (2002) 1.81
Motion of subfragment-1 in myosin and its supramolecular complexes: saturation transfer electron paramagnetic resonance. Proc Natl Acad Sci U S A (1975) 1.81
Tumor progression in four mammary epithelial cell lines derived from the same patient. Cancer Res (1990) 1.80
Tropomyosin: crystal structure, polymorphism and molecular interactions. J Mol Biol (1969) 1.79
Fluorescence energy transfer between Ca2+ transport ATPase molecules in artificial membranes. Biochemistry (1977) 1.78
A general method for the introduction of enzymes, by means of immunoglobulin-coated liposomes, into lysosomes of deficient cells. Proc Natl Acad Sci U S A (1975) 1.76
Tropomyosin paracrystals formed by divalent cations. Science (1966) 1.73
Purification and properties of the components from troponin. J Biol Chem (1973) 1.72
The Test for Severe Impairment: an instrument for the assessment of patients with severe cognitive dysfunction. J Am Geriatr Soc (1992) 1.72
Incidence and natural history of phrenic neuropathy occurring during open heart surgery. Chest (1993) 1.68
The crystal structure of modified bovine fibrinogen. Proc Natl Acad Sci U S A (2000) 1.67
Electron microscopy of thin filaments decorated with a Ca2+-regulated myosin. J Mol Biol (1980) 1.64
The action of phospholipase C on muscle microsomes: a correlation of electron microscope and biochemical data. Biochim Biophys Acta (1965) 1.63
Cooperative binding to the Ca2+-specific sites of troponin C in regulated actin and actomyosin. J Biol Chem (1983) 1.61
Troponin, tropomyosin, and actin interactions in the Ca2+ regulation of muscle contraction. Biochemistry (1974) 1.60
Structural and functional changes of myosin during development: comparison with adult fast, slow and cardiac myosin. Dev Biol (1975) 1.59
Underestimation of chronic hepatitis B virus infection in the United States of America. J Viral Hepat (2008) 1.58
Ritonavir and saquinavir combination therapy for the treatment of HIV infection. AIDS (1999) 1.58
Association of an HLA-DQ allele with clinical tuberculosis. JAMA (1998) 1.58
Microtubule structure at 18 A resolution. J Mol Biol (1987) 1.56
Social and community resources and long-term recovery from treated and untreated alcoholism. J Stud Alcohol (1997) 1.55
A model for fibrinogen: domains and sequence. Science (1985) 1.53
A 29 residue region of the sarcomeric myosin rod is necessary for filament formation. J Mol Biol (1997) 1.52
Shedding and reappearance of Fc, C3 and SRBC receptors on peripheral lymphocytes from normal donors and chronic lymphatic leukaemia (CLL) patients. Immunology (1978) 1.51
Comparative studies of the MG activated ATPase activity and Ca uptake of fractions of white and red muscle homogenates. Biochem Biophys Res Commun (1964) 1.50
Cross-bridge arrangements in Limulus muscle. J Mol Biol (1974) 1.48
A model of Ca(2+)-free calmodulin binding to unconventional myosins reveals how calmodulin acts as a regulatory switch. Structure (1996) 1.48
Troponin and its interactions with tropomyosin. An electron microscope study. J Mol Biol (1982) 1.48
Paramyosin and the filaments of molluscan "catch" muscles. I. Paramyosin: structure and assembly. J Mol Biol (1971) 1.47
Structure of co-crystals of tropomyosin and troponin. Nature (1987) 1.47
Disabled-2 inactivation is an early step in ovarian tumorigenicity. Oncogene (1999) 1.46
Pitch diversity in alpha-helical coiled coils. Proteins (1993) 1.44
Sexual and physical abuse histories and psychiatric symptoms among male psychiatric outpatients. Am J Psychiatry (1990) 1.43
Studies on myosin from red and white skeletal muscles of the rabbit. I. Adenosine triphosphatase activity. J Biol Chem (1966) 1.42
Sarcoplasmic reticulum. 8. Use of 8-anilino-1-naphthalene sulfonate as conformational probe on biological membranes. Arch Biochem Biophys (1969) 1.42
Molecular mechanism of troponin-C function. J Muscle Res Cell Motil (1992) 1.42
Inhibition of mutant troponin C activity by an intra-domain disulphide bond. Nature (1990) 1.42
Synthesis by fast muscle of myosin light chains characteristic of slow muscle in response to long-term stimulation. Nat New Biol (1973) 1.41
What transplantation can teach us about health care reform. The Ethics and Social Impact Committee. N Engl J Med (1994) 1.40
Studies on a metal-binding protein of the sarcoplasmic reticulum. J Biol Chem (1974) 1.40
DNA ploidy of ameloblastoma and ameloblastic carcinoma of the jaws. Analysis by image and flow cytometry. Arch Pathol Lab Med (1993) 1.39
Determinants of prolonged length of hospital stay after coronary bypass surgery. Circulation (1989) 1.39
Interaction of divalent cations with the 55,000-dalton protein component of the sarcoplasmic reticulum. Studies of fluorescence and circular dichroism. J Biol Chem (1972) 1.37
Effect of nucleotides and pyrophosphate on spin labels bound to S1 thiol groups of myosin. Biochemistry (1970) 1.35
Factors associated with long-term institutionalization of older people with dementia: data from the Canadian Study of Health and Aging. J Gerontol A Biol Sci Med Sci (2001) 1.35
Motions of tropomyosin. Crystal as metaphor. Biophys J (1980) 1.35
Isolation of mouse stromal cells associated with a human tumor using differential diphtheria toxin sensitivity. Am J Pathol (1999) 1.33
Sarcolipin, the "proteolipid" of skeletal muscle sarcoplasmic reticulum, is a unique, amphipathic, 31-residue peptide. Arch Biochem Biophys (1992) 1.33
Structure and modulation of neural cell adhesion molecules in early and late embryogenesis. Cold Spring Harb Symp Quant Biol (1983) 1.32
Pyrophosphate binding to and adenosine triphosphatase activity of myosin and its proteolytic fragments. Implications for the substructure of myosin. J Biol Chem (1969) 1.31
Domains, motions and regulation in the myosin head. J Muscle Res Cell Motil (1988) 1.31
Location of SH-1 and SH-2 in the heavy chain segment of heavy meromyosin. Arch Biochem Biophys (1978) 1.30
Granulomatous mastitis. A review of 5 cases. S Afr Med J (1977) 1.29
Selective stimulation of the synthesis of an 80,000-dalton protein by calcium ionophores. J Biol Chem (1981) 1.29
A model from electron microscopy for the molecular structure of fibrinogen and fibrin. Nature (1981) 1.29
Sarcoplasmic reticulum. X. The protein composition of sarcoplasmic reticulum membranes. Arch Biochem Biophys (1971) 1.29
The recognition, assessment and management of dementing disorders: conclusions from the Canadian Consensus Conference on Dementia. Can J Neurol Sci (2001) 1.27
[Ca2+]i in muscles of malignant hyperthermia susceptible pigs determined in vivo with Ca2+ selective microelectrodes. Muscle Nerve (1986) 1.26
The role of C3 in the immune response. Immunol Today (1991) 1.25
Differential expression of active mitogen-activated protein kinase in cutaneous endothelial neoplasms: implications for biologic behavior and response to therapy. J Am Acad Dermatol (2001) 1.25
Tumor angiogenesis as a prognostic factor in oral cavity tumors. Am J Surg (1994) 1.24
Structures of four Ca2+-bound troponin C at 2.0 A resolution: further insights into the Ca2+-switch in the calmodulin superfamily. Structure (1997) 1.23
Diversity of cross-bridge configurations in invertebrate muscles. Nature (1975) 1.23