Published in Lung Cancer on August 31, 2007
The Alzheimer's disease-associated amyloid beta-protein is an antimicrobial peptide. PLoS One (2010) 2.78
Alarmins: awaiting a clinical response. J Clin Invest (2012) 2.19
The pro-inflammatory peptide LL-37 promotes ovarian tumor progression through recruitment of multipotent mesenchymal stromal cells. Proc Natl Acad Sci U S A (2009) 2.07
Tumors sound the alarmin(s). Cancer Res (2008) 1.43
Understanding tumor-stroma interplays for targeted therapies by armed mesenchymal stromal progenitors: the Mesenkillers. Am J Cancer Res (2011) 1.18
Leucine leucine-37 uses formyl peptide receptor-like 1 to activate signal transduction pathways, stimulate oncogenic gene expression, and enhance the invasiveness of ovarian cancer cells. Mol Cancer Res (2009) 1.10
Human antimicrobial protein hCAP18/LL-37 promotes a metastatic phenotype in breast cancer. Breast Cancer Res (2009) 1.10
Identification of the cathelicidin peptide LL-37 as agonist for the type I insulin-like growth factor receptor. Oncogene (2011) 1.09
Emerging roles of the host defense peptide LL-37 in human cancer and its potential therapeutic applications. Int J Cancer (2010) 1.09
Host defense peptides as effector molecules of the innate immune response: a sledgehammer for drug resistance? Int J Mol Sci (2009) 1.08
Host immune defense peptide LL-37 activates caspase-independent apoptosis and suppresses colon cancer. Cancer Res (2012) 1.03
LL-37 as a therapeutic target for late stage prostate cancer. Prostate (2010) 0.95
Tumor-produced versican V1 enhances hCAP18/LL-37 expression in macrophages through activation of TLR2 and vitamin D3 signaling to promote ovarian cancer progression in vitro. PLoS One (2013) 0.94
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Effects of bacterial infection on airway antimicrobial peptides and proteins in COPD. Chest (2011) 0.94
Antimicrobial peptides in periodontal innate defense. Front Oral Biol (2011) 0.91
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Proteins and an inflammatory network expressed in colon tumors. J Proteome Res (2011) 0.81
Human antimicrobial proteins in ear wax. Eur J Clin Microbiol Infect Dis (2011) 0.81
CDA-2, a urinary preparation, inhibits lung cancer development through the suppression of NF-kappaB activation in myeloid cell. PLoS One (2012) 0.79
Cathelicidin, an antimicrobial peptide produced by macrophages, promotes colon cancer by activating the Wnt/β-catenin pathway. Oncotarget (2015) 0.79
Investigation of human cationic antimicrobial protein-18 (hCAP-18), lactoferrin and CD163 as potential biomarkers for ovarian cancer. J Ovarian Res (2013) 0.79
Cathelicidin a potential therapeutic peptide for gastrointestinal inflammation and cancer. World J Gastroenterol (2013) 0.78
Prioritization of cancer marker candidates based on the immunohistochemistry staining images deposited in the human protein atlas. PLoS One (2013) 0.78
The formylpeptide receptor 2 (Fpr2) and its endogenous ligand cathelin-related antimicrobial peptide (CRAMP) promote dendritic cell maturation. J Biol Chem (2014) 0.77
Upregulation of human β-defensin-3 and cathelicidin LL-37 in Kaposi's sarcoma. F1000Res (2012) 0.77
Activation of TRPV2 and BKCa channels by the LL-37 enantiomers stimulates calcium entry and migration of cancer cells. Oncotarget (2016) 0.76
Cathelicidin suppresses colon cancer development by inhibition of cancer associated fibroblasts. Clin Exp Gastroenterol (2014) 0.76
SPINK9 stimulates metalloprotease/EGFR-dependent keratinocyte migration via purinergic receptor activation. J Invest Dermatol (2014) 0.76
miR-663a regulates growth of colon cancer cells, after administration of antimicrobial peptides, by targeting CXCR4-p21 pathway. BMC Cancer (2017) 0.75
Antimicrobial peptide LL-37 promotes the proliferation and invasion of skin squamous cell carcinoma by upregulating DNA-binding protein A. Oncol Lett (2016) 0.75
Calcitriol stimulates gene expression of cathelicidin antimicrobial peptide in breast cancer cells with different phenotype. J Biomed Sci (2016) 0.75
Antimicrobial peptide LL-37 promotes YB-1 expression, and the viability, migration and invasion of malignant melanoma cells. Mol Med Rep (2016) 0.75
Antimicrobial peptide LL-37 promotes the viability and invasion of skin squamous cell carcinoma by upregulating YB-1. Exp Ther Med (2017) 0.75
Toll-like receptor triggering of a vitamin D-mediated human antimicrobial response. Science (2006) 18.74
Increased vascular smooth muscle contractility in TRPC6-/- mice. Mol Cell Biol (2005) 3.28
An angiogenic role for the human peptide antibiotic LL-37/hCAP-18. J Clin Invest (2003) 3.19
The long noncoding MALAT-1 RNA indicates a poor prognosis in non-small cell lung cancer and induces migration and tumor growth. J Thorac Oncol (2011) 2.79
A novel endocytic pathway induced by clustering endothelial ICAM-1 or PECAM-1. J Cell Sci (2003) 2.34
Pressure-induced and store-operated cation influx in vascular smooth muscle cells is independent of TRPC1. Pflugers Arch (2007) 2.17
Efficacy of the irreversible ErbB family blocker afatinib in epidermal growth factor receptor (EGFR) tyrosine kinase inhibitor (TKI)-pretreated non-small-cell lung cancer patients with brain metastases or leptomeningeal disease. J Thorac Oncol (2015) 1.92
Classical transient receptor potential channel 6 (TRPC6) is essential for hypoxic pulmonary vasoconstriction and alveolar gas exchange. Proc Natl Acad Sci U S A (2006) 1.89
MicroRNA replacement therapy for miR-145 and miR-33a is efficacious in a model of colon carcinoma. Cancer Res (2011) 1.79
PECAM-directed delivery of catalase to endothelium protects against pulmonary vascular oxidative stress. Am J Physiol Lung Cell Mol Physiol (2003) 1.74
The human airway epithelial basal cell transcriptome. PLoS One (2011) 1.69
RNA interference-mediated gene silencing of pleiotrophin through polyethylenimine-complexed small interfering RNAs in vivo exerts antitumoral effects in glioblastoma xenografts. Hum Gene Ther (2006) 1.65
The role of vitamin D in pulmonary disease: COPD, asthma, infection, and cancer. Respir Res (2011) 1.65
Lung adenocarcinoma subtypes based on expression of human airway basal cell genes. Eur Respir J (2013) 1.59
beta-Defensin 1 contributes to pulmonary innate immunity in mice. Infect Immun (2002) 1.57
Human endogenous antibiotic LL-37 stimulates airway epithelial cell proliferation and wound closure. Am J Physiol Lung Cell Mol Physiol (2005) 1.57
Antimicrobial peptides: current status and therapeutic potential. Drugs (2003) 1.55
Differential recognition of TLR-dependent microbial ligands in human bronchial epithelial cells. J Immunol (2007) 1.53
Superior vena cava syndrome in thoracic malignancies. Respir Care (2011) 1.52
Polyethylenimines for RNAi-mediated gene targeting in vivo and siRNA delivery to the lung. Eur J Pharm Biopharm (2010) 1.49
Comparison of two devices and two breathing patterns for exhaled breath condensate sampling. PLoS One (2011) 1.45
Liver fibrosis induced by hepatic overexpression of PDGF-B in transgenic mice. J Hepatol (2006) 1.45
Do airway epithelium air-liquid cultures represent the in vivo airway epithelium transcriptome? Am J Respir Cell Mol Biol (2010) 1.40
Increased levels of antimicrobial peptides in tracheal aspirates of newborn infants during infection. Am J Respir Crit Care Med (2002) 1.38
A low molecular weight fraction of polyethylenimine (PEI) displays increased transfection efficiency of DNA and siRNA in fresh or lyophilized complexes. J Control Release (2006) 1.37
Allergic airway inflammation inhibits pulmonary antibacterial host defense. J Immunol (2006) 1.31
The discovery of α1-antitrypsin and its role in health and disease. Respir Med (2011) 1.30
Beta-defensins and LL-37 in bronchoalveolar lavage fluid of patients with cystic fibrosis. J Cyst Fibros (2004) 1.29
RNA-Seq quantification of the human small airway epithelium transcriptome. BMC Genomics (2012) 1.28
Targeting BCL-2 family proteins to overcome drug resistance in non-small cell lung cancer. Int J Cancer (2007) 1.28
Pleiotrophin signaling through anaplastic lymphoma kinase is rate-limiting for glioblastoma growth. J Biol Chem (2002) 1.25
The transcription factor IFN regulatory factor-4 controls experimental colitis in mice via T cell-derived IL-6. J Clin Invest (2008) 1.24
Microbial patterns signaling via Toll-like receptors 2 and 5 contribute to epithelial repair, growth and survival. PLoS One (2008) 1.22
Poly(vinyl alcohol) nanofibers by electrospinning as a protein delivery system and the retardation of enzyme release by additional polymer coatings. Biomacromolecules (2005) 1.22
Potentiation of TRPC5 by protons. J Biol Chem (2007) 1.22
In vivo pharmacokinetics, tissue distribution and underlying mechanisms of various PEI(-PEG)/siRNA complexes. Toxicol Appl Pharmacol (2009) 1.21
Mcl-1 is an anti-apoptotic factor for human hepatocellular carcinoma. Int J Oncol (2006) 1.20
Serum glucose levels for predicting death in patients admitted to hospital for community acquired pneumonia: prospective cohort study. BMJ (2012) 1.20
Retracted Estradiol rapidly activates Akt via the ErbB2 signaling pathway. Mol Endocrinol (2003) 1.19
Interactions between epithelial cells and leukocytes in immunity and tissue homeostasis. J Leukoc Biol (2007) 1.18
Microbial DNA induces a host defense reaction of human respiratory epithelial cells. J Immunol (2004) 1.18
DNA methylation of TH1/TH2 cytokine genes affects sensitization and progress of experimental asthma. J Allergy Clin Immunol (2012) 1.14
The anti-microbial peptide LL-37 inhibits the activation of dendritic cells by TLR ligands. Int Immunol (2006) 1.13
HMGA2 gene is a promising target for ovarian cancer silencing therapy. Int J Cancer (2008) 1.13
In vitro MR imaging of regulated gene expression. Radiology (2003) 1.12
The antimicrobial peptide LL-37 modulates the inflammatory and host defense response of human neutrophils. Eur J Immunol (2010) 1.12
The antimicrobial peptide cathelicidin interacts with airway mucus. Peptides (2006) 1.12
Matrix metalloproteinases 2 and 9 mediate epidermal growth factor receptor transactivation by gonadotropin-releasing hormone. J Biol Chem (2003) 1.11
Gene expression profiling of malignant mesothelioma. Clin Cancer Res (2003) 1.10
Liposome-polyethylenimine complexes for enhanced DNA and siRNA delivery. Biomaterials (2010) 1.09
Treatment of non-small cell lung cancer patients with the trifunctional monoclonal antibody catumaxomab (anti-EpCAM x anti-CD3): a phase I study. Cancer Immunol Immunother (2007) 1.08
MicroRNA-449a levels increase by several orders of magnitude during mucociliary differentiation of airway epithelia. Cell Cycle (2010) 1.07
Differential sensitivity of differentiated epithelial cells to respiratory viruses reveals different viral strategies of host infection. J Virol (2008) 1.06
Association of polymorphisms of the transforming growth factor-beta1 gene with the rate of progression of HCV-induced liver fibrosis. Clin Chim Acta (2002) 1.06
Treatment of malignant pleural effusion with the trifunctional antibody catumaxomab (Removab) (anti-EpCAM x Anti-CD3): results of a phase 1/2 study. J Immunother (2009) 1.05
MDCT versus MRI assessment of tumor response after transarterial chemoembolization for the treatment of hepatocellular carcinoma. Cardiovasc Intervent Radiol (2009) 1.05
PEG grafting of polyethylenimine (PEI) exerts different effects on DNA transfection and siRNA-induced gene targeting efficacy. J Drug Target (2008) 1.04
Functions of antimicrobial peptides in host defense and immunity. Curr Protein Pept Sci (2005) 1.04
PDGFRalpha/beta expression correlates with the metastatic behavior of human colorectal cancer: a possible rationale for a molecular targeting strategy. Oncol Rep (2008) 1.04
Antimicrobial peptides in lung inflammation. Chem Immunol Allergy (2005) 1.04
FOXO transcription factors regulate innate immune mechanisms in respiratory epithelial cells. J Immunol (2013) 1.03
The fibroblast growth factor-binding protein FGF-BP. Int J Biochem Cell Biol (2005) 1.03
Chronic obstructive pulmonary disease and premature aging. Am J Respir Crit Care Med (2007) 1.02
Soluble triggering receptor expressed on myeloid cells 1 is released in patients with stable chronic obstructive pulmonary disease. Clin Dev Immunol (2007) 1.02
Strong expression of chemokine receptor CXCR4 by pancreatic cancer correlates with advanced disease. Oncol Rep (2006) 1.02
Polyethylenimine/small interfering RNA-mediated knockdown of vascular endothelial growth factor in vivo exerts anti-tumor effects synergistically with Bevacizumab. J Gene Med (2010) 1.01
The prognostic impact of blood group-related antigen Lewis Y and the ABH blood groups in resected non-small cell lung cancer. Tumour Biol (2008) 1.00
Exposure of differentiated airway epithelial cells to volatile smoke in vitro. Respiration (2004) 1.00
Analysis of the airway microbiota of healthy individuals and patients with chronic obstructive pulmonary disease by T-RFLP and clone sequencing. PLoS One (2013) 1.00
Platelet-endothelial cell adhesion molecule-1-directed immunotargeting to cardiopulmonary vasculature. J Pharmacol Exp Ther (2002) 1.00
RNA interference targeting survivin exerts antitumoral effects in vitro and in established glioma xenografts in vivo. Neuro Oncol (2011) 0.99
Streptavidin-biotin crosslinking of therapeutic enzymes with carrier antibodies: nanoconjugates for protection against endothelial oxidative stress. Methods Mol Biol (2004) 0.98
VEGF-D expression correlates with colorectal cancer aggressiveness and is downregulated by cetuximab. World J Gastroenterol (2008) 0.98
Enhanced antitumorigenic effects in glioblastoma on double targeting of pleiotrophin and its receptor ALK. Neoplasia (2009) 0.97
The cardiopulmonary continuum systemic inflammation as 'common soil' of heart and lung disease. Int J Cardiol (2010) 0.97
Tissue microarrays are reliable tools for the clinicopathological characterization of lung cancer tissue. Anticancer Res (2009) 0.96
Expression of chemokine receptor CXCR4 in esophageal squamous cell and adenocarcinoma. BMC Cancer (2006) 0.96
The role of cathelicidin and defensins in pulmonary inflammatory diseases. Expert Opin Biol Ther (2007) 0.95
Functional role and therapeutic potential of the pim-1 kinase in colon carcinoma. Neoplasia (2013) 0.94
Comparison of exhaled breath condensate pH using two commercially available devices in healthy controls, asthma and COPD patients. Respir Res (2009) 0.94