Published in Cell Cycle on August 17, 2007
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Cellular and genetic diversity in the progression of in situ human breast carcinomas to an invasive phenotype. J Clin Invest (2010) 4.22
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Targeting prostate cancer based on signal transduction and cell cycle pathways. Cell Cycle (2008) 1.25
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Targeting Aggressive Cancer Stem Cells in Glioblastoma. Front Oncol (2015) 1.05
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The cancer stem cell concept in progression of head and neck cancer. J Oncol (2009) 0.96
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CD24(+) cells fuel rapid tumor growth and display high metastatic capacity. Breast Cancer Res (2015) 0.92
The Role of Cancer Stem Cells in the Organ Tropism of Breast Cancer Metastasis: A Mechanistic Balance between the "Seed" and the "Soil"? Int J Breast Cancer (2011) 0.89
Heterogeneous kinetics of AKT signaling in individual cells are accounted for by variable protein concentration. Front Physiol (2012) 0.89
Primary breast cancer stem-like cells metastasise to bone, switch phenotype and acquire a bone tropism signature. Br J Cancer (2013) 0.88
Loss of histone H4K20 trimethylation predicts poor prognosis in breast cancer and is associated with invasive activity. Breast Cancer Res (2014) 0.88
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Landscape of somatic allelic imbalances and copy number alterations in HER2-amplified breast cancer. Breast Cancer Res (2011) 0.87
Urothelial carcinoma: stem cells on the edge. Cancer Metastasis Rev (2009) 0.86
Cancer immunoediting from immunosurveillance to tumor escape in microvillus-formed niche: a study of syngeneic orthotopic rat bladder cancer model in comparison with human bladder cancer. Neoplasia (2010) 0.85
Population genetics of cancer cell clones: possible implications of cancer stem cells. Theor Biol Med Model (2010) 0.84
ERBB2 in cat mammary neoplasias disclosed a positive correlation between RNA and protein low expression levels: a model for erbB-2 negative human breast cancer. PLoS One (2013) 0.84
Single-cell protein secretomic signatures as potential correlates to tumor cell lineage evolution and cell-cell interaction. Front Oncol (2013) 0.83
Expression distribution of cancer stem cells, epithelial to mesenchymal transition, and telomerase activity in breast cancer and their association with clinicopathologic characteristics. Clin Med Insights Pathol (2015) 0.83
Benign breast tissue composition in breast cancer patients: association with risk factors, clinical variables, and gene expression. Cancer Epidemiol Biomarkers Prev (2014) 0.83
MMP-1 is a (pre-)invasive factor in Barrett-associated esophageal adenocarcinomas and is associated with positive lymph node status. J Transl Med (2010) 0.82
Vitamin A/retinol and maintenance of pluripotency of stem cells. Nutrients (2014) 0.82
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SCNVSim: somatic copy number variation and structure variation simulator. BMC Bioinformatics (2015) 0.81
Genetic and epigenetic heterogeneity of epithelial ovarian cancer and the clinical implications for molecular targeted therapy. J Cell Mol Med (2016) 0.81
Heterogeneity of chemokine cell-surface receptor expression in triple-negative breast cancer. Am J Cancer Res (2015) 0.80
Dissecting cancer heterogeneity. Nat Biotechnol (2011) 0.80
Lung cancer stem cell: new insights on experimental models and preclinical data. J Oncol (2010) 0.80
Intra-tumor heterogeneity from a cancer stem cell perspective. Mol Cancer (2017) 0.80
A microfluidic device to select for cells based on chemotactic phenotype. Technology (Singap World Sci) (2014) 0.79
Cancer Stem and Progenitor-Like Cells as Pharmacological Targets in Breast Cancer Treatment. Breast Cancer (Auckl) (2015) 0.78
Developmental Insights into Breast Cancer Intratumoral Heterogeneity. Trends Cancer (2015) 0.78
The controversial clinicobiological role of breast cancer stem cells. J Oncol (2009) 0.78
Breast cancer stem-like cells: clinical implications and therapeutic strategies. Clujul Med (2016) 0.78
Classical pathology and mutational load of breast cancer - integration of two worlds. J Pathol Clin Res (2015) 0.78
Identification and Characterization of CXCR4-Positive Gastric Cancer Stem Cells. PLoS One (2015) 0.78
Pathology to enhance precision medicine in oncology: lessons from landscape ecology. Adv Anat Pathol (2015) 0.77
Wavelength-modulated differential photoacoustic radar imager (WM-DPARI): accurate monitoring of absolute hemoglobin oxygen saturation. Biomed Opt Express (2016) 0.77
Comprehensive prognostic analysis in breast cancer integrating clinical, tumoral, micro-environmental and immunohistochemical criteria. Springerplus (2015) 0.77
Prognostic and Predictive Significance of Stromal Fibroblasts and Macrophages in Colon Cancer. Biomark Cancer (2015) 0.77
Long-term cultures of stem/progenitor cells from lobular and ductal breast carcinomas under non-adherent conditions. Cytotechnology (2010) 0.77
Breast Cancer Cell Invasion into a Three Dimensional Tumor-Stroma Microenvironment. Sci Rep (2016) 0.77
Culture of low passage colorectal cancer cells and demonstration of variation in selected tumour marker expression. Cytotechnology (2013) 0.76
Integrating Enzymatic Self-Assembly and Mitochondria Targeting for Selectively Killing Cancer Cells without Acquired Drug Resistance. J Am Chem Soc (2016) 0.76
Serum vitamin D levels of patients with oral squamous cell carcinoma (OSCC) and expression of vitamin D receptor in oral precancerous lesions and OSCC. Med Oral Patol Oral Cir Bucal (2015) 0.76
Notch1 signaling contributes to stemness in head and neck squamous cell carcinoma. Lab Invest (2016) 0.76
Melatonin antiproliferative effects require active mitochondrial function in embryonal carcinoma cells. Oncotarget (2015) 0.76
Glutaminolysis and carcinogenesis of oral squamous cell carcinoma. Eur Arch Otorhinolaryngol (2015) 0.76
Stem cell technology in breast cancer: current status and potential applications. Stem Cells Cloning (2016) 0.76
Microcirculatory fraction (MCF(I)) as a potential imaging marker for tumor heterogeneity in breast cancer. Magn Reson Imaging (2012) 0.75
Cancer Stem Cells: Plasticity Works against Therapy. Acta Naturae (2016) 0.75
Circulating and disseminated tumor cells: diagnostic tools and therapeutic targets in motion. Oncotarget (2016) 0.75
NF-kappaΒ-inducing kinase regulates stem cell phenotype in breast cancer. Sci Rep (2016) 0.75
Hepatocyte Growth Factor, a Key Tumor-Promoting Factor in the Tumor Microenvironment. Cancers (Basel) (2017) 0.75
Cancer Stem Cells: Formidable Allies of Cancer. Indian J Surg Oncol (2015) 0.75
Hedgehog Pathway Inhibition Hampers Sphere and Holoclone Formation in Rhabdomyosarcoma. Stem Cells Int (2017) 0.75
Effect of surgical wound fluids after intraoperative electron radiotherapy on the cancer stem cell phenotype in a panel of human breast cancer cell lines. Oncol Lett (2016) 0.75
Biomarkers to Target Heterogeneous Breast Cancer Stem Cells. J Mol Biomark Diagn (2012) 0.75
Alternative therapies for metastatic breast cancer: multimodal approach targeting tumor cell heterogeneity. Breast Cancer (Dove Med Press) (2017) 0.75
One microenvironment does not fit all: heterogeneity beyond cancer cells. Cancer Metastasis Rev (2016) 0.75
The epithelial-mesenchymal transition generates cells with properties of stem cells. Cell (2008) 46.08
The genomic landscapes of human breast and colorectal cancers. Science (2007) 38.12
Mesenchymal stem cells within tumour stroma promote breast cancer metastasis. Nature (2007) 15.20
Molecular definition of breast tumor heterogeneity. Cancer Cell (2007) 12.67
Molecular characterization of the tumor microenvironment in breast cancer. Cancer Cell (2004) 9.41
Sequence analysis of mutations and translocations across breast cancer subtypes. Nature (2012) 7.76
Integrative genomic approaches identify IKBKE as a breast cancer oncogene. Cell (2007) 7.60
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Ductal carcinoma in situ of the breast. N Engl J Med (2004) 6.63
Tumor heterogeneity: causes and consequences. Biochim Biophys Acta (2009) 5.90
Profiling critical cancer gene mutations in clinical tumor samples. PLoS One (2009) 5.63
Normal and neoplastic nonstem cells can spontaneously convert to a stem-like state. Proc Natl Acad Sci U S A (2011) 5.53
Regulation of in situ to invasive breast carcinoma transition. Cancer Cell (2008) 4.46
An anatomy of normal and malignant gene expression. Proc Natl Acad Sci U S A (2002) 4.45
The JAK2/STAT3 signaling pathway is required for growth of CD44⁺CD24⁻ stem cell-like breast cancer cells in human tumors. J Clin Invest (2011) 4.41
Distinct epigenetic changes in the stromal cells of breast cancers. Nat Genet (2005) 4.33
Cellular and genetic diversity in the progression of in situ human breast carcinomas to an invasive phenotype. J Clin Invest (2010) 4.22
No evidence of clonal somatic genetic alterations in cancer-associated fibroblasts from human breast and ovarian carcinomas. Nat Genet (2008) 3.32
Heterogeneity for stem cell-related markers according to tumor subtype and histologic stage in breast cancer. Clin Cancer Res (2010) 3.19
Contribution of bone marrow-derived endothelial cells to human tumor vasculature. Nat Med (2005) 3.19
Cell type-specific DNA methylation patterns in the human breast. Proc Natl Acad Sci U S A (2008) 2.99
Cellular heterogeneity and molecular evolution in cancer. Annu Rev Pathol (2012) 2.56
Molecular markers in ductal carcinoma in situ of the breast. Mol Cancer Res (2003) 2.55
An intraductal human-in-mouse transplantation model mimics the subtypes of ductal carcinoma in situ. Breast Cancer Res (2009) 2.37
Microenvironmental regulation of cancer development. Curr Opin Genet Dev (2008) 2.25
The microenvironment in breast cancer progression: biology and implications for treatment. Breast Cancer Res (2011) 2.22
DNA methylation of RASSF1A, HIN-1, RAR-beta, Cyclin D2 and Twist in in situ and invasive lobular breast carcinoma. Int J Cancer (2003) 2.18
Control of cyclin D1 and breast tumorigenesis by the EglN2 prolyl hydroxylase. Cancer Cell (2009) 2.15
Evolutionary pathways in BRCA1-associated breast tumors. Cancer Discov (2012) 2.01
Genetic and phenotypic diversity in breast tumor metastases. Cancer Res (2014) 1.96
Genome-wide functional synergy between amplified and mutated genes in human breast cancer. Cancer Res (2008) 1.82
Role of COX-2 in epithelial-stromal cell interactions and progression of ductal carcinoma in situ of the breast. Proc Natl Acad Sci U S A (2009) 1.81
Identifying tumor origin using a gene expression-based classification map. Cancer Res (2003) 1.78
The RasGAP gene, RASAL2, is a tumor and metastasis suppressor. Cancer Cell (2013) 1.75
Combined cDNA array comparative genomic hybridization and serial analysis of gene expression analysis of breast tumor progression. Cancer Res (2006) 1.74
Glutamine sensitivity analysis identifies the xCT antiporter as a common triple-negative breast tumor therapeutic target. Cancer Cell (2013) 1.73
RNA sequencing of cancer reveals novel splicing alterations. Sci Rep (2013) 1.57
The origins and implications of intratumor heterogeneity. Cancer Prev Res (Phila) (2010) 1.55
PIK3CA mutations in in situ and invasive breast carcinomas. Cancer Res (2010) 1.49
Cancer stem cells: a model in the making. Curr Opin Genet Dev (2009) 1.48
The cancer stem cell hypothesis: in search of definitions, markers, and relevance. Lab Invest (2008) 1.47
Gene expression profiling of human breast tissue samples using SAGE-Seq. Genome Res (2010) 1.41
A neural survival factor is a candidate oncogene in breast cancer. Proc Natl Acad Sci U S A (2003) 1.41
Molecular characterisation of the tumour microenvironment in breast cancer. Eur J Cancer (2008) 1.39
Cellular and molecular targets of estrogen in normal human breast tissue. Cancer Res (2002) 1.35
Very high frequency of hypermethylated genes in breast cancer metastasis to the bone, brain, and lung. Clin Cancer Res (2004) 1.35
Stem cells in the human breast. Cold Spring Harb Perspect Biol (2010) 1.33
Epithelial and stromal cathepsin K and CXCL14 expression in breast tumor progression. Clin Cancer Res (2008) 1.31
Cancer chromosomes in crisis. Nat Genet (2004) 1.30
Psoriasin expression in mammary epithelial cells in vitro and in vivo. Cancer Res (2002) 1.29
Novel estrogen and tamoxifen induced genes identified by SAGE (Serial Analysis of Gene Expression). Oncogene (2002) 1.27
Origin of carcinoma associated fibroblasts. Cell Cycle (2009) 1.22
Clonal mutations in the cancer-associated fibroblasts: the case against genetic coevolution. Cancer Res (2009) 1.21
A putative role for psoriasin in breast tumor progression. Cancer Res (2005) 1.19
Epigenetic regulation of cell type-specific expression patterns in the human mammary epithelium. PLoS Genet (2011) 1.15
PTK6 regulates IGF-1-induced anchorage-independent survival. PLoS One (2010) 1.15
Molecular profiling of human mammary gland links breast cancer risk to a p27(+) cell population with progenitor characteristics. Cell Stem Cell (2013) 1.14
HIN-1, an inhibitor of cell growth, invasion, and AKT activation. Cancer Res (2005) 1.13
Epigenetic patterns of embryonic and adult stem cells. Cell Cycle (2009) 1.13
Breast-cancer stromal cells with TP53 mutations. N Engl J Med (2008) 1.10
Frequent HIN-1 promoter methylation and lack of expression in multiple human tumor types. Mol Cancer Res (2004) 1.10
Estrogen receptor/progesterone receptor-negative breast cancers of young African-American women have a higher frequency of methylation of multiple genes than those of Caucasian women. Clin Cancer Res (2004) 1.10
Altered antisense-to-sense transcript ratios in breast cancer. Proc Natl Acad Sci U S A (2010) 1.08
Somatic mutations in the Notch, NF-KB, PIK3CA, and Hedgehog pathways in human breast cancers. Genes Chromosomes Cancer (2012) 1.06
Targeting Akt3 signaling in triple-negative breast cancer. Cancer Res (2013) 1.06
The challenges posed by cancer heterogeneity. Nat Biotechnol (2012) 1.05
Cancer. Cancer cell phenotypes, in fifty shades of grey. Science (2013) 1.02
The receptor tyrosine kinase ErbB3 maintains the balance between luminal and basal breast epithelium. Proc Natl Acad Sci U S A (2011) 1.02
Targeting the missing links for cancer therapy. Nat Med (2011) 0.99
Psoriasin (S100A7) and calgranulin-B (S100A9) induction is dependent on reactive oxygen species and is downregulated by Bcl-2 and antioxidants. Cancer Biol Ther (2005) 0.98
Identification of CD44v6(+)/CD24- breast carcinoma cells in primary human tumors by quantum dot-conjugated antibodies. Lab Invest (2009) 0.98
S100A7-downregulation inhibits epidermal growth factor-induced signaling in breast cancer cells and blocks osteoclast formation. PLoS One (2008) 0.97
Expression of high in normal-1 (HIN-1) and uteroglobin related protein-1 (UGRP-1) in adult and developing tissues. Mech Dev (2002) 0.97
Lack of HIN-1 methylation in BRCA1-linked and "BRCA1-like" breast tumors. Cancer Res (2003) 0.91
Methylation-specific digital karyotyping of HPV16E6E7-expressing human keratinocytes identifies novel methylation events in cervical carcinogenesis. J Pathol (2013) 0.90
Serial analysis of gene expression. Nat Protoc (2006) 0.88
Cyclooxygenase-2 expression during immortalization and breast cancer progression. Cancer Res (2008) 0.88
Serial analysis of gene expression of lobular carcinoma in situ identifies down regulation of claudin 4 and overexpression of matrix metalloproteinase 9. Breast Cancer Res (2008) 0.87
Deconvoluting complex tissues for expression quantitative trait locus-based analyses. Philos Trans R Soc Lond B Biol Sci (2013) 0.87
A blueprint for an international cancer epigenome consortium. A report from the AACR Cancer Epigenome Task Force. Cancer Res (2012) 0.87
SAGE and related approaches for cancer target identification. Drug Discov Today (2006) 0.86
Methylation-specific digital karyotyping. Nat Protoc (2006) 0.84
Functional synergies yet distinct modulators affected by genetic alterations in common human cancers. Cancer Res (2011) 0.83
Tracking tumor resistance using 'liquid biopsies'. Nat Med (2013) 0.82
Cancer target discovery using SAGE. Expert Opin Ther Targets (2003) 0.81
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The expression of Psoriasin (S100A7) and CD24 is linked and related to the differentiation of mammary epithelial cells. PLoS One (2012) 0.80
EMSY links breast cancer gene 2 to the 'Royal Family'. Breast Cancer Res (2004) 0.79
Unraveling the complexity of basal-like breast cancer. Oncotarget (2011) 0.79
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