1
|
Specific microbiota direct the differentiation of IL-17-producing T-helper cells in the mucosa of the small intestine.
|
Cell Host Microbe
|
2008
|
11.08
|
2
|
Losartan, an AT1 antagonist, prevents aortic aneurysm in a mouse model of Marfan syndrome.
|
Science
|
2006
|
10.25
|
3
|
A syndrome of altered cardiovascular, craniofacial, neurocognitive and skeletal development caused by mutations in TGFBR1 or TGFBR2.
|
Nat Genet
|
2005
|
9.62
|
4
|
Making sense of latent TGFbeta activation.
|
J Cell Sci
|
2003
|
8.90
|
5
|
Myofibroblast contraction activates latent TGF-beta1 from the extracellular matrix.
|
J Cell Biol
|
2007
|
5.60
|
6
|
Latent transforming growth factor beta-binding protein 1 interacts with fibrillin and is a microfibril-associated protein.
|
J Biol Chem
|
2002
|
3.92
|
7
|
Integrin alphaVbeta6-mediated activation of latent TGF-beta requires the latent TGF-beta binding protein-1.
|
J Cell Biol
|
2004
|
2.90
|
8
|
Extracellular microfibrils: contextual platforms for TGFbeta and BMP signaling.
|
Curr Opin Cell Biol
|
2009
|
1.96
|
9
|
In vitro and in vivo evidence for shear-induced activation of latent transforming growth factor-beta1.
|
Blood
|
2008
|
1.94
|
10
|
Latent transforming growth factor beta-binding proteins and fibulins compete for fibrillin-1 and exhibit exquisite specificities in binding sites.
|
J Biol Chem
|
2009
|
1.73
|
11
|
The integrin alphaVbeta6 binds and activates latent TGFbeta3.
|
FEBS Lett
|
2002
|
1.64
|
12
|
Fibronectin is required for integrin alphavbeta6-mediated activation of latent TGF-beta complexes containing LTBP-1.
|
FASEB J
|
2005
|
1.61
|
13
|
GPR15-mediated homing controls immune homeostasis in the large intestine mucosa.
|
Science
|
2013
|
1.58
|
14
|
Isoform-specific activation of latent transforming growth factor beta (LTGF-beta) by reactive oxygen species.
|
Radiat Res
|
2006
|
1.47
|
15
|
A rapid and sensitive bioassay to measure bone morphogenetic protein activity.
|
BMC Cell Biol
|
2007
|
1.45
|
16
|
Fibrillin microfibrils: multipurpose extracellular networks in organismal physiology.
|
Physiol Genomics
|
2004
|
1.45
|
17
|
Perturbation of transforming growth factor (TGF)-beta1 association with latent TGF-beta binding protein yields inflammation and tumors.
|
Proc Natl Acad Sci U S A
|
2008
|
1.40
|
18
|
Matrix control of transforming growth factor-β function.
|
J Biochem
|
2012
|
1.39
|
19
|
LTBPs, more than just an escort service.
|
J Cell Biochem
|
2012
|
1.37
|
20
|
Bone abnormalities in latent TGF-[beta] binding protein (Ltbp)-3-null mice indicate a role for Ltbp-3 in modulating TGF-[beta] bioavailability.
|
J Cell Biol
|
2002
|
1.37
|
21
|
Mutations in LTBP4 cause a syndrome of impaired pulmonary, gastrointestinal, genitourinary, musculoskeletal, and dermal development.
|
Am J Hum Genet
|
2009
|
1.34
|
22
|
p38 MAPK is an early determinant of promiscuous Smad2/3 signaling in the aortas of fibrillin-1 (Fbn1)-null mice.
|
J Biol Chem
|
2008
|
1.32
|
23
|
Cell signaling events: a view from the matrix.
|
Matrix Biol
|
2003
|
1.26
|
24
|
Long form of latent TGF-beta binding protein 1 (Ltbp1L) is essential for cardiac outflow tract septation and remodeling.
|
Development
|
2007
|
1.22
|
25
|
Specificity of latent TGF-β binding protein (LTBP) incorporation into matrix: role of fibrillins and fibronectin.
|
J Cell Physiol
|
2012
|
1.22
|
26
|
Dual functions for LTBP in lung development: LTBP-4 independently modulates elastogenesis and TGF-beta activity.
|
J Cell Physiol
|
2009
|
1.14
|
27
|
Unchaining the beast; insights from structural and evolutionary studies on TGFβ secretion, sequestration, and activation.
|
Cytokine Growth Factor Rev
|
2013
|
1.08
|
28
|
Lung alveolar septation defects in Ltbp-3-null mice.
|
Am J Pathol
|
2005
|
1.08
|
29
|
E-selectin ligand-1 regulates growth plate homeostasis in mice by inhibiting the intracellular processing and secretion of mature TGF-beta.
|
J Clin Invest
|
2010
|
1.05
|
30
|
Latent TGF-β binding protein 4 promotes elastic fiber assembly by interacting with fibulin-5.
|
Proc Natl Acad Sci U S A
|
2013
|
1.04
|
31
|
Differential effects of alendronate and losartan therapy on osteopenia and aortic aneurysm in mice with severe Marfan syndrome.
|
Hum Mol Genet
|
2010
|
1.03
|
32
|
Microfibril structure masks fibrillin-2 in postnatal tissues.
|
J Biol Chem
|
2010
|
1.03
|
33
|
Mechanisms of tendon injury and repair.
|
J Orthop Res
|
2015
|
1.02
|
34
|
Expression of truncated latent TGF-beta-binding protein modulates TGF-beta signaling.
|
J Cell Sci
|
2005
|
1.02
|
35
|
Solution structure of the third TB domain from LTBP1 provides insight into assembly of the large latent complex that sequesters latent TGF-beta.
|
J Mol Biol
|
2003
|
0.99
|
36
|
Amino acid requirements for formation of the TGF-beta-latent TGF-beta binding protein complexes.
|
J Mol Biol
|
2005
|
0.98
|
37
|
An osteoblast-derived proteinase controls tumor cell survival via TGF-beta activation in the bone microenvironment.
|
PLoS One
|
2012
|
0.95
|
38
|
Latent transforming growth factor-beta-binding protein-4 regulates transforming growth factor-beta1 bioavailability for activation by fibrogenic lung fibroblasts in response to bleomycin.
|
Am J Pathol
|
2008
|
0.95
|
39
|
Latent TGF-beta binding protein-3 (LTBP-3) requires binding to TGF-beta for secretion.
|
FEBS Lett
|
2002
|
0.95
|
40
|
Methods for measuring TGF-b using antibodies, cells, and mice.
|
Methods Mol Med
|
2005
|
0.93
|
41
|
F-spondin, a neuroregulatory protein, is up-regulated in osteoarthritis and regulates cartilage metabolism via TGF-beta activation.
|
FASEB J
|
2008
|
0.93
|
42
|
Annexin II-mediated plasmin generation activates TGF-beta3 during epithelial-mesenchymal transformation in the developing avian heart.
|
Dev Biol
|
2004
|
0.90
|
43
|
Thrombospondin-1 (TSP-1) analogs ABT-510 and ABT-898 inhibit prolactinoma growth and recover active pituitary transforming growth factor-β1 (TGF-β1).
|
Endocrinology
|
2012
|
0.88
|
44
|
Active and total transforming growth factor-β1 are differentially regulated by dopamine and estradiol in the pituitary.
|
Endocrinology
|
2011
|
0.88
|
45
|
Long form of latent TGF-β binding protein 1 (Ltbp1L) regulates cardiac valve development.
|
Dev Dyn
|
2011
|
0.88
|
46
|
Control of lung development by latent TGF-β binding proteins.
|
J Cell Physiol
|
2011
|
0.87
|
47
|
Function of latent TGFβ binding protein 4 and fibulin 5 in elastogenesis and lung development.
|
J Cell Physiol
|
2015
|
0.87
|
48
|
Growth retardation as well as spleen and thymus involution in latent TGF-beta binding protein (Ltbp)-3 null mice.
|
J Cell Physiol
|
2003
|
0.86
|
49
|
The latent-TGFbeta-binding-protein-1 (LTBP-1) is expressed in the organizer and regulates nodal and activin signaling.
|
Dev Biol
|
2002
|
0.84
|
50
|
Production of gastrointestinal tumors in mice by modulating latent TGF-β1 activation.
|
Cancer Res
|
2012
|
0.83
|
51
|
Molecular cloning of the mouse Ltbp-1 gene reveals tissue specific expression of alternatively spliced forms.
|
Gene
|
2003
|
0.82
|
52
|
A genetic screen to identify latent transforming growth factor beta activators.
|
Anal Biochem
|
2004
|
0.81
|
53
|
Overexpression of the 18 kDa and 22/24 kDa FGF-2 isoforms results in differential drug resistance and amplification potential.
|
J Cell Physiol
|
2002
|
0.79
|
54
|
Sex differences in the pituitary transforming growth factor-β1 system: studies in a model of resistant prolactinomas.
|
Endocrinology
|
2013
|
0.78
|
55
|
Genetic suppression of inflammation blocks the tumor-promoting effects of TGF-β in gastric tissue.
|
Cancer Res
|
2014
|
0.77
|
56
|
Is losartan the drug for all seasons?
|
Curr Opin Pharmacol
|
2012
|
0.76
|