Published in Structure on September 01, 2007
Fragile X mental retardation protein regulates translation by binding directly to the ribosome. Mol Cell (2014) 1.83
ZBP1 recognition of beta-actin zipcode induces RNA looping. Genes Dev (2010) 1.63
Discrimination of common and unique RNA-binding activities among Fragile X mental retardation protein paralogs. Hum Mol Genet (2009) 1.53
New perspectives on the biology of fragile X syndrome. Curr Opin Genet Dev (2012) 1.23
Structure of a construct of a human poly(C)-binding protein containing the first and second KH domains reveals insights into its regulatory mechanisms. J Biol Chem (2008) 1.20
Phosphorylation-mediated unfolding of a KH domain regulates KSRP localization via 14-3-3 binding. Nat Struct Mol Biol (2009) 1.14
SpliceAid-F: a database of human splicing factors and their RNA-binding sites. Nucleic Acids Res (2012) 1.06
Protein-RNA and protein-protein recognition by dual KH1/2 domains of the neuronal splicing factor Nova-1. Structure (2011) 1.01
Roles of Dim2 in ribosome assembly. J Biol Chem (2010) 0.98
Multi-disciplinary methods to define RNA-protein interactions and regulatory networks. Curr Opin Genet Dev (2013) 0.97
FMR1 transcript isoforms: association with polyribosomes; regional and developmental expression in mouse brain. PLoS One (2013) 0.91
Fragile X syndrome due to a missense mutation. Eur J Hum Genet (2014) 0.90
Orientation of the central domains of KSRP and its implications for the interaction with the RNA targets. Nucleic Acids Res (2010) 0.90
FMRP interacts with G-quadruplex structures in the 3'-UTR of its dendritic target Shank1 mRNA. RNA Biol (2014) 0.89
A study of the ultrastructure of fragile-X-related proteins. Biochem J (2009) 0.88
A presynaptic role for FMRP during protein synthesis-dependent long-term plasticity in Aplysia. Learn Mem (2010) 0.86
Human FMRP contains an integral tandem Agenet (Tudor) and KH motif in the amino terminal domain. Hum Mol Genet (2014) 0.85
Recombinant bacterial expression and purification of human fragile X mental retardation protein isoform 1. Protein Expr Purif (2010) 0.85
Crystal structure of human polynucleotide phosphorylase: insights into its domain function in RNA binding and degradation. Nucleic Acids Res (2011) 0.85
Nuclear Fragile X Mental Retardation Protein is localized to Cajal bodies. PLoS Genet (2013) 0.83
Fragile X mental retardation protein: A paradigm for translational control by RNA-binding proteins. Biochimie (2015) 0.81
Differential increases of specific FMR1 mRNA isoforms in premutation carriers. J Med Genet (2014) 0.78
The N-terminus of FILIA forms an atypical KH domain with a unique extension involved in interaction with RNA. PLoS One (2012) 0.78
Crystal structure of a dimerization domain of human Caprin-1: insights into the assembly of an evolutionarily conserved ribonucleoprotein complex consisting of Caprin-1, FMRP and G3BP1. Acta Crystallogr D Struct Biol (2016) 0.76
TPR proteins: the versatile helix. Trends Biochem Sci (2003) 7.37
Design of stable alpha-helical arrays from an idealized TPR motif. Structure (2003) 3.17
Detecting protein-protein interactions with a green fluorescent protein fragment reassembly trap: scope and mechanism. J Am Chem Soc (2005) 2.95
Structure and function of KH domains. FEBS J (2008) 2.48
Identification of differentially expressed proteins in ovarian cancer using high-density protein microarrays. Proc Natl Acad Sci U S A (2007) 2.22
A recurring theme in protein engineering: the design, stability and folding of repeat proteins. Curr Opin Struct Biol (2005) 1.58
A new folding paradigm for repeat proteins. J Am Chem Soc (2005) 1.57
The interface of protein structure, protein biophysics, and molecular evolution. Protein Sci (2012) 1.54
Detecting protein-protein interactions with GFP-fragment reassembly. Nat Methods (2004) 1.45
The folding and design of repeat proteins: reaching a consensus. Curr Opin Struct Biol (2003) 1.43
Liquid-liquid phase transition in supercooled yttria-alumina. Phys Rev Lett (2009) 1.42
Sequence variation in ligand binding sites in proteins. BMC Bioinformatics (2005) 1.37
Structure and stability of designed TPR protein superhelices: unusual crystal packing and implications for natural TPR proteins. Acta Crystallogr D Biol Crystallogr (2007) 1.33
A direct interaction between the Utp6 half-a-tetratricopeptide repeat domain and a specific peptide in Utp21 is essential for efficient pre-rRNA processing. Mol Cell Biol (2008) 1.30
Protein design to understand peptide ligand recognition by tetratricopeptide repeat proteins. Protein Eng Des Sel (2004) 1.28
Designed TPR modules as novel anticancer agents. ACS Chem Biol (2008) 1.28
Local and long-range stability in tandemly arrayed tetratricopeptide repeats. Proc Natl Acad Sci U S A (2005) 1.28
Ligand binding by TPR domains. Protein Sci (2006) 1.25
Protein-protein interactions: general trends in the relationship between binding affinity and interfacial buried surface area. Protein Sci (2013) 1.20
A novel class of small molecule inhibitors of Hsp90. ACS Chem Biol (2008) 1.19
Ligand binding by repeat proteins: natural and designed. Curr Opin Struct Biol (2008) 1.19
Balance between folding and degradation for Hsp90-dependent client proteins: a key role for CHIP. Biochemistry (2010) 1.17
Integrin alpha v beta 6 is an RGD-dependent receptor for coxsackievirus A9. J Virol (2004) 1.16
The structure and catalytic cycle of a sodium-pumping pyrophosphatase. Science (2012) 1.16
Beyond consensus: statistical free energies reveal hidden interactions in the design of a TPR motif. J Mol Biol (2004) 1.14
Identification of residues on Hsp70 and Hsp90 ubiquitinated by the cochaperone CHIP. J Mol Biol (2009) 1.11
A new bright green-emitting fluorescent protein--engineered monomeric and dimeric forms. FEBS J (2010) 1.04
Consensus design as a tool for engineering repeat proteins. Methods Mol Biol (2006) 1.01
NMR and crystal structures of the Pyrococcus horikoshii RadA intein guide a strategy for engineering a highly efficient and promiscuous intein. J Mol Biol (2012) 1.01
Revisiting the Ramachandran plot from a new angle. Protein Sci (2011) 1.00
Combinatorial approaches to protein stability and structure. Eur J Biochem (2004) 0.99
Covariation of backbone motion throughout a small protein domain. Nat Struct Biol (2003) 0.98
The crystal structure of NlpI. A prokaryotic tetratricopeptide repeat protein with a globular fold. FEBS J (2005) 0.97
Redesign of a protein-peptide interaction: characterization and applications. Protein Sci (2009) 0.96
Crystal structure of a designed tetratricopeptide repeat module in complex with its peptide ligand. FEBS J (2010) 0.96
Electrostatic interactions of Hsp-organizing protein tetratricopeptide domains with Hsp70 and Hsp90: computational analysis and protein engineering. J Biol Chem (2009) 0.95
A compound that inhibits the HOP-Hsp90 complex formation and has unique killing effects in breast cancer cell lines. Mol Pharm (2011) 0.95
Mutations in the B1 domain of protein G that delay the onset of amyloid fibril formation in vitro. Protein Sci (2003) 0.94
Mapping the energy landscape of repeat proteins using NMR-detected hydrogen exchange. J Mol Biol (2008) 0.94
Screening libraries to identify proteins with desired binding activities using a split-GFP reassembly assay. ACS Chem Biol (2010) 0.93
Both domain 19 and domain 20 of factor H are involved in binding to complement C3b and C3d. Mol Immunol (2010) 0.93
A cell-based screen for function of the four-helix bundle protein Rop: a new tool for combinatorial experiments in biophysics. Protein Eng Des Sel (2004) 0.92
Structural and functional analysis of coxsackievirus A9 integrin αvβ6 binding and uncoating. J Virol (2013) 0.92
Non-random-coil behavior as a consequence of extensive PPII structure in the denatured state. J Mol Biol (2008) 0.92
HOP is a monomer: investigation of the oligomeric state of the co-chaperone HOP. Protein Sci (2010) 0.92
Intermolecular domain swapping induces intein-mediated protein alternative splicing. Nat Chem Biol (2013) 0.91
Kinetics and thermodynamics of phenotype: unwinding and rewinding the nucleosome. J Mol Biol (2012) 0.90
Calorimetric study of a series of designed repeat proteins: modular structure and modular folding. Protein Sci (2011) 0.90
An AlphaScreen-based high-throughput screen to identify inhibitors of Hsp90-cochaperone interaction. J Biomol Screen (2009) 0.90
Stimuli-responsive smart gels realized via modular protein design. J Am Chem Soc (2010) 0.89
A new method for the covalent attachment of DNA to a surface for single-molecule studies. Colloids Surf B Biointerfaces (2010) 0.89
Designed proteins to modulate cellular networks. ACS Chem Biol (2010) 0.89
Methyl-thiazoles: a novel mode of inhibition with the potential to develop novel inhibitors targeting InhA in Mycobacterium tuberculosis. J Med Chem (2013) 0.88
A twisted four-sheeted model for an amyloid fibril. Structure (2005) 0.88
Creating novel proteins by combining design and selection. Protein Eng Des Sel (2010) 0.87
Structural basis for complement evasion by Lyme disease pathogen Borrelia burgdorferi. J Biol Chem (2013) 0.86
Methionine-121 coordination determines metal specificity in unfolded Pseudomonas aeruginosa azurin. J Biol Inorg Chem (2004) 0.86
Reassembled GFP: detecting protein-protein interactions and protein expression patterns. Methods Biochem Anal (2006) 0.85
The PA4204 gene encodes a periplasmic gluconolactonase (PpgL) which is important for fitness of Pseudomonas aeruginosa. Microbiology (2008) 0.85
Analysis of side chain mobility among protein G B1 domain mutants with widely varying stabilities. Protein Sci (2004) 0.85
A modular approach to the design of protein-based smart gels. Biopolymers (2012) 0.85
Repeat motions and backbone flexibility in designed proteins with different numbers of identical consensus tetratricopeptide repeats. Biochemistry (2006) 0.84
A structural model for the HAT domain of Utp6 incorporating bioinformatics and genetics. Protein Eng Des Sel (2009) 0.84
Does the location of a mutation determine the ability to form amyloid fibrils? J Mol Biol (2002) 0.83
New insights into Fragile X syndrome. Relating genotype to phenotype at the molecular level. FEBS J (2005) 0.82
The structure of the NTPase that powers DNA packaging into Sulfolobus turreted icosahedral virus 2. J Virol (2013) 0.82
LC-MS based assay to measure intracellular compound levels in Mycobacterium smegmatis: linking compound levels to cellular potency. J Microbiol Methods (2013) 0.82
The power of hard-sphere models: explaining side-chain dihedral angle distributions of Thr and Val. Biophys J (2012) 0.82
Characterization of folding the four-helix bundle protein Rop by real-time NMR. Protein Eng Des Sel (2008) 0.82
Designed phosphoprotein recognition in Escherichia coli. ACS Chem Biol (2014) 0.81
Predicting the side-chain dihedral angle distributions of nonpolar, aromatic, and polar amino acids using hard sphere models. Proteins (2014) 0.81
Cloning, expression, purification, crystallization and preliminary X-ray diffraction data of the Pyrococcus horikoshii RadA intein. Acta Crystallogr Sect F Struct Biol Cryst Commun (2011) 0.81
Modulating repeat protein stability: the effect of individual helix stability on the collective behavior of the ensemble. Protein Sci (2011) 0.79
Conservation of mechanism, variation of rate: folding kinetics of three homologous four-helix bundle proteins. Protein Eng Des Sel (2008) 0.79
Chemical short-range order in liquid Al-Ni alloys. J Chem Phys (2008) 0.78
Crystallization and preliminary X-ray analysis of membrane-bound pyrophosphatases. Mol Membr Biol (2012) 0.78
New materials from proteins and peptides. Curr Opin Struct Biol (2012) 0.78
Structure guided lead generation for M. tuberculosis thymidylate kinase (Mtb TMK): discovery of 3-cyanopyridone and 1,6-naphthyridin-2-one as potent inhibitors. J Med Chem (2014) 0.78
Nanostructured functional films from engineered repeat proteins. J R Soc Interface (2013) 0.78
Structure of Plasmodium falciparum TRAP (thrombospondin-related anonymous protein) A domain highlights distinct features in apicomplexan von Willebrand factor A homologues. Biochem J (2013) 0.77
New insights into the interdependence between amino acid stereochemistry and protein structure. Biophys J (2013) 0.77
Comparison of the backbone dynamics of a natural and a consensus designed 3-TPR domain. J Biomol NMR (2008) 0.76
Structure-based engineering and comparison of novel split inteins for protein ligation. Mol Biosyst (2014) 0.76
Probing the Molecular Origin of Native-State Flexibility in Repeat Proteins. J Am Chem Soc (2015) 0.76
White and green screening with circular polymerase extension cloning for easy and reliable cloning. Protein Sci (2013) 0.75
Site-specific protein double labeling by expressed protein ligation: applications to repeat proteins. Org Biomol Chem (2011) 0.75
Crystallization and preliminary crystallographic analysis of mouse peroxiredoxin II with significant pseudosymmetry. Acta Crystallogr Sect F Struct Biol Cryst Commun (2010) 0.75
Intrinsic α-helical and β-sheet conformational preferences: a computational case study of alanine. Protein Sci (2014) 0.75
Protein engineering and design: from first principles to new technologies. Curr Opin Struct Biol (2010) 0.75
Flat Drops, Elastic Sheets and Microcapsules by Interfacial Assembly of a Bacterial Biofilm Protein, BslA. Langmuir (2017) 0.75
Fully connected Bayesian belief networks: a modeling procedure with a case study of the Ganges river basin. Integr Environ Assess Manag (2011) 0.75
Editorial overview: Mechanistic biology: Dynamic interactions in biology-sensing change. Curr Opin Chem Biol (2015) 0.75
Protein folding and design: from simple models to complex systems. Curr Opin Struct Biol (2008) 0.75
Library approaches to biophysical problems. Eur J Biochem (2004) 0.75
3-Carboxy-cis,cis-muconate lactonizing enzyme from Neurospora crassa: MAD phasing with 80 selenomethionines. Acta Crystallogr D Biol Crystallogr (2002) 0.75