The nicotinic acetylcholine receptor gene family of the silkworm, Bombyx mori.

De novo characterization of a whitefly transcriptome and analysis of its gene expression during development. BMC Genomics (2010) 5.17

Mis-spliced transcripts of nicotinic acetylcholine receptor alpha6 are associated with field evolved spinosad resistance in Plutella xylostella (L.). PLoS Genet (2010) 1.22

Discovery of genes related to insecticide resistance in Bactrocera dorsalis by functional genomic analysis of a de novo assembled transcriptome. PLoS One (2012) 1.02

The Drosophila nicotinic acetylcholine receptor subunits Dα5 and Dα7 form functional homomeric and heteromeric ion channels. BMC Neurosci (2012) 0.89

Transcripts of the nicotinic acetylcholine receptor subunit gene Pxylα6 with premature stop codons are associated with spinosad resistance in diamondback moth, Plutella xylostella. Invert Neurosci (2010) 0.88

A fungal metabolite asperparaline a strongly and selectively blocks insect nicotinic acetylcholine receptors: the first report on the mode of action. PLoS One (2011) 0.83

Insect nicotinic acetylcholine receptor agonists as flea adulticides in small animals. J Vet Pharmacol Ther (2010) 0.81

De novo transcriptome and expression profile analyses of the Asian corn borer (Ostrinia furnacalis) reveals relevant flubendiamide response genes. BMC Genomics (2017) 0.81

Mining genes involved in insecticide resistance of Liposcelis bostrychophila Badonnel by transcriptome and expression profile analysis. PLoS One (2013) 0.80

Acetylcholine-binding protein in the hemolymph of the planorbid snail Biomphalaria glabrata is a pentagonal dodecahedron (60 subunits). PLoS One (2012) 0.79

Larval Helicoverpa zea Transcriptional, Growth and Behavioral Responses to Nicotine and Nicotiana tabacum. Insects (2014) 0.77

A CRISPR/Cas9 mediated point mutation in the alpha 6 subunit of the nicotinic acetylcholine receptor confers resistance to spinosad in Drosophila melanogaster. Insect Biochem Mol Biol (2016) 0.77

De novo assembly and characterization of central nervous system transcriptome reveals neurotransmitter signaling systems in the rice striped stem borer, Chilo suppressalis. BMC Genomics (2015) 0.76

Transcription analysis of neonicotinoid resistance in Mediterranean (MED) populations of B. tabaci reveal novel cytochrome P450s, but no nAChR mutations associated with the phenotype. BMC Genomics (2015) 0.76

Transcriptome analysis of neonatal larvae after hyperthermia-induced seizures in the contractile silkworm, Bombyx mori. PLoS One (2014) 0.76

Alternative splicing of the Anopheles gambiae nicotinic acetylcholine receptor, Agamalphabeta9, generates both alpha and beta subunits. Invert Neurosci (2009) 0.76

Insecticide resistance mediated by an exon skipping event. Mol Ecol (2016) 0.75

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A draft sequence for the genome of the domesticated silkworm (Bombyx mori). Science (2004) 6.62

Production of human beta interferon in insect cells infected with a baculovirus expression vector. Mol Cell Biol (1983) 5.00

The genome sequence of silkworm, Bombyx mori. DNA Res (2004) 4.27

Nicotinic receptors at the amino acid level. Annu Rev Pharmacol Toxicol (2000) 4.04

Neonicotinoid insecticide toxicology: mechanisms of selective action. Annu Rev Pharmacol Toxicol (2005) 3.57

Neonicotinoids: insecticides acting on insect nicotinic acetylcholine receptors. Trends Pharmacol Sci (2001) 2.35

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Assembly and subunit diversity of nicotinic acetylcholine receptors. Biochem Soc Trans (2003) 1.62

Functional modulation of the nicotinic acetylcholine receptor by tyrosine phosphorylation. Nature (1988) 1.57

The nicotinic acetylcholine receptor gene family of the honey bee, Apis mellifera. Genome Res (2006) 1.36

Nicotinic acetylcholine receptors: targets for commercially important insecticides. Invert Neurosci (2007) 1.28

Fast excitatory synaptic transmission mediated by nicotinic acetylcholine receptors in Drosophila neurons. J Neurosci (1999) 1.14

The nicotinic acetylcholine receptor gene family of the malaria mosquito, Anopheles gambiae. Genomics (2005) 1.06

RNA editing and alternative splicing of the insect nAChR subunit alpha6 transcript: evolutionary conservation, divergence and regulation. BMC Evol Biol (2007) 1.02

Edit, cut and paste in the nicotinic acetylcholine receptor gene family of Drosophila melanogaster. Bioessays (2005) 1.01

Exploring the pharmacological properties of insect nicotinic acetylcholine receptors. Trends Pharmacol Sci (2006) 0.99

Diverse actions of neonicotinoids on chicken alpha7, alpha4beta2 and Drosophila-chicken SADbeta2 and ALSbeta2 hybrid nicotinic acetylcholine receptors expressed in Xenopus laevis oocytes. Neuropharmacology (2003) 0.96

Structure and function of AChBP, homologue of the ligand-binding domain of the nicotinic acetylcholine receptor. Ann N Y Acad Sci (2003) 0.94

Cloning and heterologous expression of Dalpha4, a Drosophila neuronal nicotinic acetylcholine receptor subunit: identification of an alternative exon influencing the efficiency of subunit assembly. Neuropharmacology (2000) 0.93

Identification of an alternatively processed nicotinic receptor alpha7 subunit RNA in mouse brain. Brain Res Mol Brain Res (2003) 0.90

N-glycosylation sites on the nicotinic ACh receptor subunits regulate receptor channel desensitization and conductance. Brain Res Mol Brain Res (2003) 0.89

De novo characterization of a whitefly transcriptome and analysis of its gene expression during development. BMC Genomics (2010) 5.17

WNK4 regulates the balance between renal NaCl reabsorption and K+ secretion. Nat Genet (2003) 4.08

Data Processing System (DPS) software with experimental design, statistical analysis and data mining developed for use in entomological research. Insect Sci (2012) 3.56

Transcriptome analysis of the brown planthopper Nilaparvata lugens. PLoS One (2010) 2.00

Alternative splicing of an insect sodium channel gene generates pharmacologically distinct sodium channels. J Neurosci (2002) 1.80

Altered trafficking and stability of polycystins underlie polycystic kidney disease. J Clin Invest (2014) 1.71

Identification of amino acid residues in the insect sodium channel critical for pyrethroid binding. Mol Pharmacol (2004) 1.57

Global analysis of the transcriptional response of whitefly to tomato yellow leaf curl China virus reveals the relationship of coevolved adaptations. J Virol (2011) 1.54

Knockdown of RCK/p54 expression by RNAi inhibits proliferation of human colorectal cancer cells in vitro and in vivo. Cancer Biol Ther (2008) 1.50

RNA editing generates tissue-specific sodium channels with distinct gating properties. J Biol Chem (2004) 1.50

Absence of small conductance K+ channel (SK) activity in apical membranes of thick ascending limb and cortical collecting duct in ROMK (Bartter's) knockout mice. J Biol Chem (2002) 1.49

Molecular evidence for dual pyrethroid-receptor sites on a mosquito sodium channel. Proc Natl Acad Sci U S A (2013) 1.44

Diversity and Convergence of Sodium Channel Mutations Involved in Resistance to Pyrethroids. Pestic Biochem Physiol (2013) 1.38

Genomes of the rice pest brown planthopper and its endosymbionts reveal complex complementary contributions for host adaptation. Genome Biol (2014) 1.34

Inhibition of protein-tyrosine phosphatase stimulates the dynamin-dependent endocytosis of ROMK1. J Biol Chem (2001) 1.32

Inducing apoptosis and enhancing chemosensitivity to gemcitabine via RNA interference targeting Mcl-1 gene in pancreatic carcinoma cell. Cancer Chemother Pharmacol (2008) 1.24

A voltage-gated calcium-selective channel encoded by a sodium channel-like gene. Neuron (2004) 1.24

Nucleotides and phospholipids compete for binding to the C terminus of KATP channels. Proc Natl Acad Sci U S A (2002) 1.23

A sodium channel mutation identified in Aedes aegypti selectively reduces cockroach sodium channel sensitivity to type I, but not type II pyrethroids. Insect Biochem Mol Biol (2010) 1.23

Drosophila as a model for epilepsy: bss is a gain-of-function mutation in the para sodium channel gene that leads to seizures. Genetics (2010) 1.23

The insecticidal potential of scorpion beta-toxins. Toxicon (2006) 1.23

Identification of a cluster of residues in transmembrane segment 6 of domain III of the cockroach sodium channel essential for the action of pyrethroid insecticides. Biochem J (2009) 1.21

Comparative analysis of the genomes of Bombyx mandarina and Bombyx mori nucleopolyhedroviruses. J Microbiol (2010) 1.19

Use of non-mammalian alternative models for neurotoxicological study. Neurotoxicology (2008) 1.17

Phosphorylation-regulated endoplasmic reticulum retention signal in the renal outer-medullary K+ channel (ROMK). Proc Natl Acad Sci U S A (2005) 1.15

The differential preference of scorpion alpha-toxins for insect or mammalian sodium channels: implications for improved insect control. Toxicon (2006) 1.12

Persistent tetrodotoxin-sensitive sodium current resulting from U-to-C RNA editing of an insect sodium channel. Proc Natl Acad Sci U S A (2004) 1.08

Molecular and functional characterization of voltage-gated sodium channel variants from Drosophila melanogaster. Insect Biochem Mol Biol (2008) 1.06

Induction of HIV neutralizing antibodies against the MPER of the HIV envelope protein by HA/gp41 chimeric protein-based DNA and VLP vaccines. PLoS One (2011) 1.06

Gene expression profiling of resistant and susceptible Bombyx mori strains reveals nucleopolyhedrovirus-associated variations in host gene transcript levels. Genomics (2009) 1.05

Chitin synthase 1 gene and its two alternative splicing variants from two sap-sucking insects, Nilaparvata lugens and Laodelphax striatellus (Hemiptera: Delphacidae). Insect Biochem Mol Biol (2012) 1.03

Dynamic interactions between Bombyx mori nucleopolyhedrovirus and its host cells revealed by transcriptome analysis. J Virol (2012) 1.01

Inhibiting proliferation and enhancing chemosensitivity to taxanes in osteosarcoma cells by RNA interference-mediated downregulation of stathmin expression. Mol Med (2007) 1.01

Subunit-subunit interactions are critical for proton sensitivity of ROMK: evidence in support of an intermolecular gating mechanism. Proc Natl Acad Sci U S A (2006) 1.01

Identification of new batrachotoxin-sensing residues in segment IIIS6 of the sodium channel. J Biol Chem (2011) 1.00

ROMK1 channel activity is regulated by monoubiquitination. Proc Natl Acad Sci U S A (2005) 0.98

Molecular determinants on the insect sodium channel for the specific action of type II pyrethroid insecticides. Toxicol Appl Pharmacol (2008) 0.98

Genome sequence of a Bombyx mori nucleopolyhedrovirus strain with cubic occlusion bodies. J Virol (2012) 0.98

Immunization by influenza virus-like particles protects aged mice against lethal influenza virus challenge. Antiviral Res (2009) 0.98

Molecular characterization of an arachnid sodium channel gene from the varroa mite (Varroa destructor). Insect Biochem Mol Biol (2003) 0.98

Mechanism of action of sodium channel blocker insecticides (SCBIs) on insect sodium channels. Pestic Biochem Physiol (2010) 0.97

Genome sequence and organization of a nucleopolyhedrovirus that infects the tea looper caterpillar, Ectropis obliqua. Virology (2006) 0.97

Molecular basis of differential sensitivity of insect sodium channels to DCJW, a bioactive metabolite of the oxadiazine insecticide indoxacarb. Neurotoxicology (2005) 0.97

Molecular characterization and functional expression of the DSC1 channel. Insect Biochem Mol Biol (2011) 0.96

De novo intestine-specific transcriptome of the brown planthopper Nilaparvata lugens revealed potential functions in digestion, detoxification and immune response. Genomics (2012) 0.96

ODV-associated proteins of the Pieris rapae granulovirus. J Proteome Res (2011) 0.93

Apoptosis induction effects of EGCG in laryngeal squamous cell carcinoma cells through telomerase repression. Arch Pharm Res (2009) 0.93

An alanine in segment 3 of domain III (IIIS3) of the cockroach sodium channel contributes to the low pyrethroid sensitivity of an alternative splice variant. Insect Biochem Mol Biol (2005) 0.93

Genomic insights into the glutathione S-transferase gene family of two rice planthoppers, Nilaparvata lugens (Stål) and Sogatella furcifera (Horváth) (Hemiptera: Delphacidae). PLoS One (2013) 0.92

Role of the sixth transmembrane segment of domain IV of the cockroach sodium channel in the action of sodium channel blocker insecticides. Neurotoxicology (2009) 0.92

Synergistic interaction between two cockroach sodium channel mutations and a tobacco budworm sodium channel mutation in reducing channel sensitivity to a pyrethroid insecticide. Insect Biochem Mol Biol (2002) 0.92

Antibiotic resistance of probiotic strains of lactic acid bacteria isolated from marketed foods and drugs. Biomed Environ Sci (2009) 0.91

Molecular characterization of the flightin gene in the wing-dimorphic planthopper, Nilaparvata lugens, and its evolution in Pancrustacea. Insect Biochem Mol Biol (2013) 0.91

Morphological, phylogenetic and biological characteristics of Ectropis obliqua single-nucleocapsid nucleopolyhedrovirus. J Microbiol (2006) 0.91

Characterization of a Baculovirus newly isolated from the tea slug moth, Iragoidae fasciata. J Microbiol (2009) 0.91

RNA interference of NADPH-cytochrome P450 reductase of the rice brown planthopper, Nilaparvata lugens, increases susceptibility to insecticides. Pest Manag Sci (2014) 0.91

The genome- and transcriptome-wide analysis of innate immunity in the brown planthopper, Nilaparvata lugens. BMC Genomics (2013) 0.91

The carboxyl termini of K(ATP) channels bind nucleotides. J Biol Chem (2002) 0.90

Differentially expressed genes in resistant and susceptible Bombyx mori strains infected with a densonucleosis virus. Insect Biochem Mol Biol (2008) 0.90

Label-free classification of cultured cells through diffraction imaging. Biomed Opt Express (2011) 0.90

Role of the DSC1 channel in regulating neuronal excitability in Drosophila melanogaster: extending nervous system stability under stress. PLoS Genet (2013) 0.90

Direct interactions between bidensovirus BmDNV-Z proteins and midgut proteins from the virus target Bombyx mori. FEBS J (2013) 0.88

Effect of a fluvalinate-resistance-associated sodium channel mutation from varroa mites on cockroach sodium channel sensitivity to fluvalinate, a pyrethroid insecticide. Insect Biochem Mol Biol (2006) 0.88

microRNA-34a sensitizes lung cancer cell lines to DDP treatment independent of p53 status. Cancer Biother Radiopharm (2012) 0.87

Evolutionary adaptation of the amino acid and codon usage of the mosquito sodium channel following insecticide selection in the field mosquitoes. PLoS One (2012) 0.87

Mouse cystic fibrosis transmembrane conductance regulator forms cAMP-PKA-regulated apical chloride channels in cortical collecting duct. Proc Natl Acad Sci U S A (2010) 0.87

Bombyx mori nucleopolyhedrovirus ORF9 is a gene involved in the budded virus production and infectivity. J Gen Virol (2009) 0.87

A negative charge in transmembrane segment 1 of domain II of the cockroach sodium channel is critical for channel gating and action of pyrethroid insecticides. Toxicol Appl Pharmacol (2010) 0.86

Overexpression of astrocyte-elevated gene-1 is associated with cervical carcinoma progression and angiogenesis. Oncol Rep (2013) 0.86

Molecular characterization of DSC1 orthologs in invertebrate species. Insect Biochem Mol Biol (2012) 0.86

Serum anti-AEG-1 auto-antibody is a potential novel biomarker for malignant tumors. Oncol Lett (2012) 0.85

Tumor-specific adenovirus-mediated PUMA gene transfer using the survivin promoter enhances radiosensitivity of breast cancer cells in vitro and in vivo. Breast Cancer Res Treat (2008) 0.84

Adhesion and immunomodulatory effects of Bifidobacterium lactis HN019 on intestinal epithelial cells INT-407. World J Gastroenterol (2010) 0.84

Molecular characterization of a sodium channel gene from the Silkworm Bombyx mori. Insect Biochem Mol Biol (2008) 0.84

Triazophos up-regulated gene expression in the female brown planthopper, Nilaparvata lugens. J Insect Physiol (2010) 0.84

Functional expression of an arachnid sodium channel reveals residues responsible for tetrodotoxin resistance in invertebrate sodium channels. J Biol Chem (2009) 0.84

Involvement of Bombyx mori nucleopolyhedrovirus ORF41 (Bm41) in BV production and ODV envelopment. Virology (2009) 0.83

The BH3-only protein PUMA is involved in green tea polyphenol-induced apoptosis in colorectal cancer cell lines. Cancer Biol Ther (2008) 0.83

Analysis of the action of lidocaine on insect sodium channels. Insect Biochem Mol Biol (2010) 0.83

An immune-induced reeler protein is involved in the Bombyx mori melanization cascade. Insect Biochem Mol Biol (2011) 0.83

A new continuous cell line from larval ovaries of silkworm, Bombyx mori. In Vitro Cell Dev Biol Anim (2009) 0.83

Characterization of Bombyx mori nucleopolyhedrovirus with a deletion of bm118. Virus Res (2008) 0.83

Open reading frame 60 of the Bombyx mori nucleopolyhedrovirus plays a role in budded virus production. Virus Res (2010) 0.82

Immunization with a Mixture of HIV Env DNA and VLP Vaccines Augments Induction of CD8 T Cell Responses. J Biomed Biotechnol (2010) 0.82

Hypoxia-inducible enhancer/alpha-fetoprotein promoter-driven RNA interference targeting STK15 suppresses proliferation and induces apoptosis in human hepatocellular carcinoma cells. Cancer Sci (2008) 0.82

The therapeutic potential of survivin promoter-driven siRNA on suppressing tumor growth and enhancing radiosensitivity of human cervical carcinoma cells via downregulating hTERT gene expression. Cancer Biol Ther (2007) 0.82

A baculovirus isolated from wild silkworm encompasses the host ranges of Bombyx mori nucleopolyhedrosis virus and Autographa californica multiple nucleopolyhedrovirus in cultured cells. J Gen Virol (2012) 0.82

Isolated polycystic liver disease genes define effectors of polycystin-1 function. J Clin Invest (2017) 0.82

Bactericidal activity against meticillin-resistant Staphylococcus aureus of a novel eukaryotic therapeutic recombinant antimicrobial peptide. Int J Antimicrob Agents (2012) 0.82

Bombyx mori nucleopolyhedrovirus ORF56 encodes an occlusion-derived virus protein and is not essential for budded virus production. J Gen Virol (2008) 0.81

The ionotropic γ-aminobutyric acid receptor gene family of the silkworm, Bombyx mori. Genome (2010) 0.81

Identification of a novel functional nuclear localization signal in the protein encoded by open reading frame 47 of Bombyx mori nucleopolyhedrovirus. Arch Virol (2010) 0.81

Suppression of Bcl-xL expression by a novel tumor-specific RNA interference system inhibits proliferation and enhances radiosensitivity in prostatic carcinoma cells. Cancer Chemother Pharmacol (2007) 0.81

Reduced expression of 14-3-3 gamma in uterine leiomyoma as identified by proteomics. Fertil Steril (2007) 0.81

AEG-1 overexpression is essential for maintenance of malignant state in human AML cells via up-regulation of Akt1 mediated by AURKA activation. Cell Signal (2013) 0.81

Wilms' tumour suppressor gene 1 (WT1) is involved in the carcinogenesis of Lung cancer through interaction with PI3K/Akt pathway. Cancer Cell Int (2013) 0.81

Expression and regulation of the yggG gene of Escherichia coli. Curr Microbiol (2007) 0.81

The Genome of Pieris rapae Granulovirus. J Virol (2012) 0.81