Published in Proc Natl Acad Sci U S A on March 15, 2010
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Identification of amino acid residues in the insect sodium channel critical for pyrethroid binding. Mol Pharmacol (2004) 1.57
Knockdown of RCK/p54 expression by RNAi inhibits proliferation of human colorectal cancer cells in vitro and in vivo. Cancer Biol Ther (2008) 1.50
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Absence of small conductance K+ channel (SK) activity in apical membranes of thick ascending limb and cortical collecting duct in ROMK (Bartter's) knockout mice. J Biol Chem (2002) 1.49
Calcium-sensing receptor abrogates secretagogue- induced increases in intestinal net fluid secretion by enhancing cyclic nucleotide destruction. Proc Natl Acad Sci U S A (2006) 1.48
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Molecular evidence for dual pyrethroid-receptor sites on a mosquito sodium channel. Proc Natl Acad Sci U S A (2013) 1.44
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Regulation of the expression of the Cl-/anion exchanger pendrin in mouse kidney by acid-base status. Kidney Int (2002) 1.32
Inhibition of protein-tyrosine phosphatase stimulates the dynamin-dependent endocytosis of ROMK1. J Biol Chem (2001) 1.32
Abnormal trafficking and degradation of TLR4 underlie the elevated inflammatory response in cystic fibrosis. J Immunol (2011) 1.31
Characteristics of renal Rhbg as an NH4(+) transporter. Am J Physiol Renal Physiol (2004) 1.29
Inhibition of MAPK stimulates the Ca2+ -dependent big-conductance K channels in cortical collecting duct. Proc Natl Acad Sci U S A (2006) 1.25
A voltage-gated calcium-selective channel encoded by a sodium channel-like gene. Neuron (2004) 1.24
Inducing apoptosis and enhancing chemosensitivity to gemcitabine via RNA interference targeting Mcl-1 gene in pancreatic carcinoma cell. Cancer Chemother Pharmacol (2008) 1.24
Nucleotides and phospholipids compete for binding to the C terminus of KATP channels. Proc Natl Acad Sci U S A (2002) 1.23
A sodium channel mutation identified in Aedes aegypti selectively reduces cockroach sodium channel sensitivity to type I, but not type II pyrethroids. Insect Biochem Mol Biol (2010) 1.23
Drosophila as a model for epilepsy: bss is a gain-of-function mutation in the para sodium channel gene that leads to seizures. Genetics (2010) 1.23
The insecticidal potential of scorpion beta-toxins. Toxicon (2006) 1.23
WNK protein kinases modulate cellular Cl- flux by altering the phosphorylation state of the Na-K-Cl and K-Cl cotransporters. Physiology (Bethesda) (2006) 1.22
Identification of a cluster of residues in transmembrane segment 6 of domain III of the cockroach sodium channel essential for the action of pyrethroid insecticides. Biochem J (2009) 1.21
Protein tyrosine kinase is expressed and regulates ROMK1 location in the cortical collecting duct. Am J Physiol Renal Physiol (2004) 1.19
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Active K+ secretion through multiple KCa-type channels and regulation by IKCa channels in rat proximal colon. Am J Physiol Gastrointest Liver Physiol (2003) 1.17
The nicotinic acetylcholine receptor gene family of the silkworm, Bombyx mori. BMC Genomics (2007) 1.16
Assessment of cystic fibrosis transmembrane conductance regulator (CFTR) activity in CFTR-null mice after bone marrow transplantation. Proc Natl Acad Sci U S A (2006) 1.16
Phosphorylation-regulated endoplasmic reticulum retention signal in the renal outer-medullary K+ channel (ROMK). Proc Natl Acad Sci U S A (2005) 1.15
The differential preference of scorpion alpha-toxins for insect or mammalian sodium channels: implications for improved insect control. Toxicon (2006) 1.12
Persistent tetrodotoxin-sensitive sodium current resulting from U-to-C RNA editing of an insect sodium channel. Proc Natl Acad Sci U S A (2004) 1.08
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Phorbol ester stimulation of RasGRP1 regulates the sodium-chloride cotransporter by a PKC-independent pathway. Proc Natl Acad Sci U S A (2007) 1.06
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Activity of the renal Na+-K+-2Cl- cotransporter is reduced by mutagenesis of N-glycosylation sites: role for protein surface charge in Cl- transport. Am J Physiol Renal Physiol (2005) 1.05
The functions and roles of the extracellular Ca2+-sensing receptor along the gastrointestinal tract. Annu Rev Physiol (2009) 1.04
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Inhibiting proliferation and enhancing chemosensitivity to taxanes in osteosarcoma cells by RNA interference-mediated downregulation of stathmin expression. Mol Med (2007) 1.01
Subunit-subunit interactions are critical for proton sensitivity of ROMK: evidence in support of an intermolecular gating mechanism. Proc Natl Acad Sci U S A (2006) 1.01
Identification of new batrachotoxin-sensing residues in segment IIIS6 of the sodium channel. J Biol Chem (2011) 1.00
A rapid enzymatic method for the isolation of defined kidney tubule fragments from mouse. Pflugers Arch (2003) 1.00
Partial correction of cystic fibrosis defects with PLGA nanoparticles encapsulating curcumin. Mol Pharm (2010) 0.99
ROMK1 channel activity is regulated by monoubiquitination. Proc Natl Acad Sci U S A (2005) 0.98
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Molecular characterization of an arachnid sodium channel gene from the varroa mite (Varroa destructor). Insect Biochem Mol Biol (2003) 0.98
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CFTR is required for PKA-regulated ATP sensitivity of Kir1.1 potassium channels in mouse kidney. J Clin Invest (2006) 0.97
Mechanism of action of sodium channel blocker insecticides (SCBIs) on insect sodium channels. Pestic Biochem Physiol (2010) 0.97
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Molecular characterization and functional expression of the DSC1 channel. Insect Biochem Mol Biol (2011) 0.96
ROMK is required for expression of the 70-pS K channel in the thick ascending limb. Am J Physiol Renal Physiol (2003) 0.96
Mouse model of type II Bartter's syndrome. I. Upregulation of thiazide-sensitive Na-Cl cotransport activity. Am J Physiol Renal Physiol (2008) 0.94
Localization of the ATP/phosphatidylinositol 4,5 diphosphate-binding site to a 39-amino acid region of the carboxyl terminus of the ATP-regulated K+ channel Kir1.1. J Biol Chem (2002) 0.94
The calcium-sensing receptor acts as a modulator of gastric acid secretion in freshly isolated human gastric glands. Am J Physiol Gastrointest Liver Physiol (2005) 0.94
An alanine in segment 3 of domain III (IIIS3) of the cockroach sodium channel contributes to the low pyrethroid sensitivity of an alternative splice variant. Insect Biochem Mol Biol (2005) 0.93
Apoptosis induction effects of EGCG in laryngeal squamous cell carcinoma cells through telomerase repression. Arch Pharm Res (2009) 0.93
Role of the sixth transmembrane segment of domain IV of the cockroach sodium channel in the action of sodium channel blocker insecticides. Neurotoxicology (2009) 0.92
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Association between serum 25-hydroxyvitamin D level and pulmonary exacerbations in cystic fibrosis. Pediatr Pulmonol (2015) 0.91
The carboxyl termini of K(ATP) channels bind nucleotides. J Biol Chem (2002) 0.90
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A novel protein kinase signaling pathway essential for blood pressure regulation in humans. Trends Endocrinol Metab (2008) 0.90
New aspects of renal potassium transport. Pflugers Arch (2003) 0.90
Role of the DSC1 channel in regulating neuronal excitability in Drosophila melanogaster: extending nervous system stability under stress. PLoS Genet (2013) 0.90